• Title/Summary/Keyword: WDP

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Single-dose Intravenous Injection Toxicity of Water-soluble Danggui Pharmacopuncture (WDP) in Sprague-Dawley Rats

  • Park, Sunju;Park, Hae-Mo;Sun, Seung-Ho
    • Journal of Pharmacopuncture
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    • v.21 no.2
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    • pp.104-111
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    • 2018
  • Objective:This study is to evaluate both the single-dose intravenous injection toxicity and the approximate lethal dose of Water-soluble Danggui Pharmacopuncture (WDP) in Sprague-Dawley (SD) rats. Methods: Toxicity experiments were conducted at Good Laboratory Practice (GLP) laboratory in Biotoxtech Co., according to the regulations of GLP. WDP injection of dose 0.125, 0.25, and 0.5 mL/animal were experimental groups and normal saline injection group was control group. WDP and normal saline were injected once to 6- week old 5 male and 5 female SD rats at the tail veins at approximately 2 mL/min. During 14 days after the injection, general symptoms were observed and weight were measured. After the observation period, hematological and blood biochemical examination, macroscopic autopsy, topical resistance test at the injection area were performed. Results: RThe WDP 0.5 mL/animal injection group in 4 cases of male rats and all cases of female rats showed hematuria 30 minutes after the administration. However, after 1 hour, no more abnormal general symptoms were observed. The WDP did not affect weight, hematological and blood biochemical examination, macroscopic autopsy, and topical resistance test at the injection area. Conclusion: WDP single dose intravenous injection results showed that WDP have no toxic effects and a lethal dose of WDP should be over 0.5 mL/animal in male and female rats under the study condition. So WDP may be safe.

Scalability Analysis of MANET IPv6 Address Auto-configuration Protocols based on Link Error Modeling (링크 에러 모델링을 이용한 MANET 환경에서의 IPv6 자동주소 설정 방식의 확장성 분석)

  • Kim, Sang-Chul
    • Journal of KIISE:Information Networking
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    • v.35 no.4
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    • pp.282-291
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    • 2008
  • This paper focuses on message complexity performance analysis of MANET AAPs in reference to link errors generated by the mobile wireless nodes. To obtain the message complexity performance of AAPs in reference to the link error probability ($P_e$), an enhancement was made by proposing the retransmission limit (S) to be computed for error recovery (based on the link error probability), and then for each of the AAPs the control procedures for the retransmission limit have been properly included. The O-notation has been applied in analyzing the upper bound of the number of messages generated by a MANET group of N nodes. Based on a link error probability range of $P_e=0$ to 0.8, the AAPs investigated in this paper are Strong DAD, Weak DAD with proactive routing protocol (WDP), Weak DAD with on-demand routing protocol (WDO), and MANETconf. Based on the simulation results and analysis of the message complexity, for nominal situations, the message complexity of WDP was lowest, closely followed by WDO. The message complexity of MANETconf is higher than that of WDO, and Strong DAD results to be most complex among the four AAPs.

Experimental Study on the Spray Behavior of Non-Esterification Biodiesel Fuel (비에스테르화 바이오디젤유의 분무거동에 대한 실험적 연구)

  • Choi, S.H.;Oh, Y.T.
    • Journal of ILASS-Korea
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    • v.14 no.3
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    • pp.117-121
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    • 2009
  • Biodiesel fuel has different spray patterns, because viscosity and surface tension of biodiesel fuel are higher than that of diesel fuel. The diesel combustion is strongly controlled by the fuel spray behavior in combustion chamber. So, it was needed to understand the spay characteristics of non-esterification biodiesel fuel. In this study, the spray characteristics of non-esterification biodiesel fuel was investigated to confirm of an effect of WDP. The characteristics of fuel atomization was analyzed with SMD and span factor through laser diffraction particle analyzer (LDPA), and the process of spray injection was visualized through the visualization system composed of a halogen lamp and high speed camera. It was found that injection delay time and SMD of blended fuel with WDP get shoter and smaller than that of non-esterification biodiesel fuel.

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Analysis of Link Error Effects in MANET Address Autoconfiguration Protocols

  • Kim, Sang-Chul;Chung, Jong-Moon
    • Journal of Communications and Networks
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    • v.11 no.1
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    • pp.84-93
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    • 2009
  • This paper focuses on message complexity performance analysis of mobile ad hoc network (MANET) address autoconfiguration protocols (AAPs) in reference to link errors generated by mobile wireless nodes. An enhancement was made using a proposed retransmission limit, S, to be computed for error recovery (based on the link error probability), to measure message complexity of AAPs in reference to the link error probability, $P_e$. The control procedures for the retransmission limit have been included for each of the AAPs. Retransmission limit control is critical for efficient energy consumption of MANET nodes operating on limited portable energy. O-notation has been applied to analyze the upper bound of the number of messages generated by a MANET group of nodes. The AAPs investigated in this paper are strong duplicate address detection (DAD), weak DAD with proactive routing protocol (WDP), weak DAD with on-demand routing protocol (WDO), and MANETConf. Each AAP reacts different to link errors, as each AAP has different operational procedures. The required number of broadcasting, unicasting, relaying, and received messages of the nodes participating in a single-node joining procedure is investigated to asymptotically calculate the message complexity of each AAP. Computer simulation was conducted and the results have been analyzed to verify the theoretical message complexity bounds derived. The message complexity of WDP was lowest, closely followed byWDO, based on the simulation results and analysis of the message complexity under nominal situations. The message complexity of MANETConf was higher than WDO, and strong DAD resulted to be most complex among the four AAPs.

Population Dynamics of Zacco platypus in Gap-Stream and Its Relation with Water Quality

  • Shin, Young-Eun; Choi, Ji-Woon;An, Kwang-Guk
    • Korean Journal of Ecology and Environment
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    • v.42 no.4
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    • pp.422-431
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    • 2009
  • This study was to provide basic data for aquatic ecosystem research using fishes. Field sampling was carried out at five selected sites of Gap Stream, and fish samples, especially for a selection of sentinel species were collected three times in June, September, and October 2007. We analyzed total length distribution of Zacco platypus in relation with the season and the sampling sites, and then compared with total body weight, condition factor (K), and age distribution of the fish. The fish population data were compared with physico-chemical water quality, obtained from the Ministry of Environment, Korea. Water quality analysis showed a significant nutrient enrichment, based on total nitrogen (TN) and total phosphorus (TP), and organic matter pollution, based on biological oxygen demand (BOD) and chemical oxygen demand (COD) in the Site 5, which is directly influenced by wastewater disposal plant (WDP). Population analysis of the sentinel species showed that the total number of individuals, age distribution, and the population size-structure were influenced by the effluents from the WDP, and that reproductive failure of young-age population were evident in Site 5. According to the relation analysis of total weight to K, the disturbed population was mainly attributed to combined effects of habitat modifications and chemical degradations. Regression analysis of K values against water quality parameters showed significant (p<0.05) positive relations with nutrient and organic matter contents. Our data suggest that the population structure using a sentinel fish species reflected the ambient water quality in the stream and that diagnosis of aquatic ecosystem health using Z. platypus population may be practical for water resource and ecosystem conservations.

Design of WAP Gateway for Multi-Users (다중 사용자를 위한 WAP GATEWAY 설계)

  • Bae, Sung-Bum;Myong, Sang-Tae;Jung, Hwan-Ik;Lee, Kwang-Hyung
    • Proceedings of the Korea Information Processing Society Conference
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    • 2001.04a
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    • pp.469-472
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    • 2001
  • 본 논문은 WAP 스펙 1.1에 기반 하였으며 WAP 서비스 구조는 마이크로 브라우저, 클라이언트 그리고 게이트웨이로 나누어 질 수 있다. 브라우저는 사용자 인터페이스 부분이고 클라이언트는 사용자 단말기에서 WAP 게이트웨이와 상호 통신할 수 있는 프로토콜 층이다. 게이트웨이는 WAP 서비스에서 가장 중요한 역할을 하는 서버부분이다. 이 같은 구성 요소를 가지고 WAP 시스템을 구성하였으며 또한 서비스를 할 수 있는 시뮬레이션을 구현하였다. 클라이언트 부분과 게이트웨이 부분은 리눅스 OS 기반으로 WAP 스펙 1.1에서 정의된 모든 이벤트를 함수로 모듈화 하였고 각 프로토콜 층과의 인터페이스는 사용자 임의의 정의로 구현하였다. 그 외 보안을 담당해주는 WTLS층은 고려하지 않아도 WAP 서비스를 할 수 있으므로 시스템에서는 생략하였으며 또한 WDP층도 단지 데이터만을 전송해주는 의미밖에 없으므로 TCP/IP 상에서 소켓통신으로 구현하였다.

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FDG-PET and MDP scan findings in chronic osteomyelitis of the left femur (좌측 대퇴골에 발생한 만성골수염의 PET와 MDP scan 영상)

  • Park, Chan-H.;Lee, Myoung-Hoon
    • The Korean Journal of Nuclear Medicine
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    • v.36 no.2
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    • pp.143-145
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    • 2002
  • A 49-year-old male patient with a carcinoma of the right pyriform sinus had a whole-body bone scan and gamma camera based F-18 FDG-PET for staging. Tc-99m MDP bone scan depicted diffuse increased uptake in the left femur due to chronic osteomyelitis but no skeletal metastasis. F-18-FDG-PET revealed increased focal bone uptake and uptake in the draining sinus due to chronic osteomyelitis in addition to visualization of the right pyriform sinus carcinoma and right neck nodal uptake. Fluorine-18 fluorodeoxyglucose-positron emission tomography is significantly more accurate than the bone scan in pinpointing chronic osteomyelitis focus and draining soft tissue infection.

Preliminary Studies on the Necropsy-Based Health Assessment Index (HAI) Using a Ecological Indicator Species (생태 지표종을 이용한 해부학적 건강성 평가지수(HAI) 적용을 위한 예비실험)

  • Kim, Ja-Hyun;Bae, Dae-Yeul;Lee, Jae-Yon;An, Kwang-Guk
    • Korean Journal of Ecology and Environment
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    • v.39 no.1 s.115
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    • pp.62-72
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    • 2006
  • Biological health in aquatic environments has been assessed by several approaches using various bio-taxa. Especially, fish has been identified as one of the best ecological indicators for an integrative health assessments in aquatic environments. In this preliminary study, the necropsy-based approach using the Health Assessment Index (Adams et al., 1993; HAI, Blazer, 2000), was employed for the assessments of aquatic environments influenced by effluent water from wastewater disposal plants (WDP) near a urban stream (i.e., Cap-Stream). For the impact analysis from the effluents, we developed 10 metric necropsy-based model including $M_l\;skin,\;M_2\;fin,\;M_3\;thymus,\;M_4\;spleen,\;M_5\;hindgut,\;M_6\;kidney,\;M_7\;liver.\;M_8\;eyes,\;M_9\;gill,\;and\;M_{10}$ pseudobranch. We set up duplicate controls (natural upstream water plus 5 fishes in each control tank) and duplicate treatments (effluent water from the WDP plus 5 fishes in each treatment tank) in the laboratory. Preliminary results showed that HAI values in the controls were zero, indicating an excellent condition by the criteria of HAI, while the HAI values in the treatments ranged between 40 and 150, indicating a poor condition. Also, various health conditions, based on the index of biological integrity (IBI), species richness, tolerance guilds, and trophic guilds supported the HAI approach. The HAI approach, not applied in Korea, not may be used as an surrogate fer ecological health assessment in lotic ecosystems.

Crop Water Stress Index (CWSI) Mapping for Evaluation of Abnormal Growth of Spring Chinese Cabbage Using Drone-based Thermal Infrared Image (봄배추 생육이상 평가를 위한 드론 열적외 영상 기반 작물 수분 스트레스 지수(CWSI) 분포도 작성)

  • Na, Sang-il;Ahn, Ho-yong;Park, Chan-won;Hong, Suk-young;So, Kyu-ho;Lee, Kyung-do
    • Korean Journal of Remote Sensing
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    • v.36 no.5_1
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    • pp.667-677
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    • 2020
  • Crop water stress can be detected based on soil moisture content, crop physiological characteristics and remote-sensing technology. The detection of crop water stress is an important issue for the accurate assessment of yield decline. The crop water stress index (CWSI) has been introduced based on the difference between leaf and air temperature. In this paper, drone-based thermal infrared image was used to map of crop water stress in water control plot (WCP) and water deficit plot (WDP) over spring chinese cabbage fields. The spatial distribution map of CWSI was in strong agreement with the abnormal growth response factors (plant height, plant diameter, and measured value by chlorophyll meter). From these results, CWSI can be used as a good method for evaluation of crop abnormal growth monitoring.

A study on the wire reduction design and effect analysis for the train vehicle line (화물열차 분산제어시스템 개발에 관한 연구)

  • Lee, Kangmi;Lee, Jaeho;Yoon, Yong-Ki
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.12
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    • pp.778-784
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    • 2017
  • In this paper, we propose wired and wireless distributed control systems designed to improve the freight logistics efficiency and verify wired distributed control systems. The verification condition required that 50 cargo vehicles be connected and operated to travel 21 km from Busan Sinhang station to Jinlye Station at an average speed of about 100km/h. The verification results show that the traction output and braking output of the control and controlled cars are dispersed by the wired distributed control system. The application is expected to more than double the efficiency of the logistics compared to the existing freight transportation system. However, in the case of the wired distributed control system, cable installation and maintenance are difficult, and it is impossible to change the combination of freight vehicles. Through the verification of the wired distributed control system, the applicability of distributed control systems to freight vehicles in Korea was confirmed and the system was further developed to produce a wireless distributed control system. In order to apply the wireless distributed control system, a propagation environment analysis for the ISM band was performed in the testbed and, as a result, it was confirmed that Wifi technology using the ISM band could be utilized. In order to use the WDP (Wireless Distributed Power) devices newly installed in the target vehicles, the transmission / reception control signals associated with the propulsion / braking / total control devices are defined. In the case of wireless distributed control systems, the convenience of their application and operation is guaranteed, but reliability and emergency safety measures should because of the dependence of the control of the vehicle on radio signals.