• Title/Summary/Keyword: W126

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Forsythiae Fructus Extract Inhibits RANKL-Induced Osteoclast Differentiation and Prevent Bone Loss in OVX-Induced Osteoporosis Rat (연교의 파골세포 분화 및 골 흡수 억제 기전 연구)

  • Eom, Ji-Whan;Kim, Jae-Hyun;Kim, Minsun;Kim, Sangwoo;Shin, Hwajeong;Jung, Hyuk-Sang;Sohn, Youngjoo
    • Korean Journal of Acupuncture
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    • v.36 no.2
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    • pp.115-126
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    • 2019
  • Objectives : Osteoporosis is a condition characterized by low bone mass and increased bone fragility. It has become a major problem of senior citizens. The purpose of this study is to experiment the effect of water extract of Forsythiae Fructus (wFF) on osteoclast differentiation; and the other purpose is to examine the effect of wFF on osteoporosis in ovariectomized rat. Methods : To investigate the effect of wFF on osteoclast differentiation and activity, RAW 264.7 cells were used. The number of TRAP positive cell, TRAP activity, pit area, mRNA expression of makers (RANK, TRAP, CA II, CTK, MMP-9, NFATc1, c-Fos), protein expression of makers (NFATc1, c-Fos) were investigated. For in vivo study, 40 female Sprague-Dawley (SD) rats were induced osteoporosis by ovariectomy (OVX) and then tested for anti-osteoporosis effect by administration of wFF. Results : wFF suppressed osteoclatogenesis, TRAP activity and pit area formation. Moreover, wFF decreased the expression of master differentiation factors (NFATc1, c-Fos) and also reduced the osteoclastogenesis-related markers (TRAP, CA II, CTK, MMP-9). These suggest that wFF inhibit osteoclasts differentiation and bone resorption. In the OVX rat model, wFF inhibited decreasing of BMD and trabecular area. Conclusions : Forsythiae Fructus should be effective for osteoporosis prevention and treatment.

Study on the Reproduction and Growth of Iksookimia koreensis Kim (Pisces: Cobitidae) in the Namdae Stream, Cheorwon-gun, Gangwon-do Korea (강원도 철원군 남대천에 서식하는 참종개의 성장과 번식에 관한 연구)

  • Kim, Dohong;Cho, Hae-Young;Lee, Ho-Sa
    • Korean Journal of Ichthyology
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    • v.20 no.1
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    • pp.21-27
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    • 2008
  • A total sample of 215 specimens of the Iksookimia koreensis was collected monthly from June 2004 to June 2005 in the Namdae stream, Cheorwon-gun, Gangwon-do, Korea. The age of every individual sample was estimated by the number of annual rings on the scales. A significant decrease of gonadosomatic index was noted between May and June reflecting the reproduction during this period. I. koreensis exhibited a strong bias to female (female : male, 1 : 0.56). The maximum age observed was 3 years old for male & female, both. The von Bertalanffy growth curves were expressed as $L_t=126.30[1-\exp\{-0.576(t+0.940)\}]$ for females and $L_t=100.19[1-\exp\{-1.119(t+0.695)\}]$ for males.Growth curve of weight was expressed as $W_t=11.567[1-\exp\{-0.576(t+0.940)\}]^{3.199}$ for females, $W_t=5.514[1-\exp\{-1.119(t+0.695)\}]^{3.199}$ for males. On the other hand, a significant difference in the growth rate between both sexes was found(i.e. females grew faster than males).

Heritabilities and Genetic Correlations on Economic Traits in Layers (난용계의 주요경제형질에 대한 유전력 및 유전상관)

  • 상병찬;한성욱;정선부
    • Korean Journal of Poultry Science
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    • v.16 no.2
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    • pp.73-81
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    • 1989
  • This study was conducted to estimate heritabilities, genetic and phenotypic correlations on economic traits in layers. The data analysis were the records of 351 pullets in S. C. W. Leghorn and 326 pullets in R. I. Red from March 1, 1980 to July 31.1981. The results obtained are summarized as follows:1 The average body weights at the first egg, 300 and 500 days of age were 1, 409, 1, 602 and 1, 709g S. C. W. Leghorn, and 1, 965, 2, 305, and 2, 479g in the R. I. Red, respectively. The age at first egg of the S. C. W, Leghorn and R. I. Red were 156 days and 163 days, respectively. The number of egg produced by the S. C. W. Leghorn and R. I. Red to 300 days and 500 days of age were 101.18, 214.39, and 101.05, 214.93, respectively. The egg weight at first egg, 300 and 500 days of age were 41.93, 57.65 and 60.33g in the S. C. W. Leghorn and 41.52, 57.62 and 60.57g in the R. I. Red, respectively. 2. The heritability estimates based on the variance of sire and dam components were 0.402-0.612 and 0.275-0.458 in the S. C. W. Leghorn, 0.309-0.523 and 0.134-0.380 in R. I. Red for body weight; 0.167 and 0.139 in the 5. C. W. Leghorn, 0.169 and 0.095 in the R.1. Red for age at first egg:0.214-0.139 and 0.336-0.341 in S. C. W Leghorn, 0.137-0.259 and 0.024-0.102 in the R. I. Red for number of egg production; 0.537-0.769 and 0.374-0.686 in the S. C. W. Leghorn, 0.519-0.631 and 0.116-0.365 in the R. I. Red for egg weight, respectively. 3. The genetic correlation coefficients of economic traits were as follows: In the S. C. W. Leghorn and R. I. Red , the coefficients between body weights and age at the first egg, 0.328-0.426 and 0.186-0.244:between body weights and number of egg production, -0.666--0.498 and -0.452--0.073:between body weight and egg weight, 0.384-0.774 and 0.126-0.612; between age at first egg and number of egg production, -0.639--0.452 and -0.754--0.320; between age at first egg and egg weight, 0.475-0.705 and 0.021-0.605; between number of egg production and egg weight, -0.623--0.355 and -0.861--0.327, respectively.

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A Study on Wear Mechanism of CBN Ball Endmills (CBN 볼엔드밀의 마모메카니즘에 관한 연구)

  • Park, S.W.;Lee, K.W.;Lee, J.C.
    • Journal of the Korean Society for Precision Engineering
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    • v.14 no.12
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    • pp.121-126
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    • 1997
  • The use of CBN tool material has been greatly increased because of the superior metal cutting performance for the machining of hardened steel. This paper presents some experimental results on the ball endmiling of harened steels. Three different hardnesses of STD11 workpieces were machined using CBN ball endimills, and the machining characteristics including cutting forces tool wear, and surface roughness of machined surface were compared. It has been found that the CBN ball endmill works better in the machining of harder workpieces. The microscopic examination explains that this unusual phenomenon is caused by the difference of microstructure of each workpieces.

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Anti-oxidant Effect of Wasabia Japonica Extracts (고추냉이 추출액의 항산화 효과)

  • Lee, Young-Sun
    • Journal of Society of Preventive Korean Medicine
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    • v.12 no.1
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    • pp.119-126
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    • 2008
  • This study was carried out to investigate the anti-oxidant effect of Wasabia japonica(WJ). The anti-oxidant activities of various extracts from WJ were investigated. The water and ethanol extracts of WJ leaf were found to cause significant free radical scavenging effects on DPPH and nitric oxide(NO). Sprague-Dawley male rats were randomly assigned to one normal diet and three high cholesterol diet groups which contained 1%(w/w) cholesterol. After 4weeks cholesterol diet, the groups of high cholesterol diet were classified to control(normal diet only), WJR5(normal diet and 5% WJ root) and WJL5(normal diet and 5% WJ leaf). Liver xanthine oxidase(XO) activity in the rats of high cholesterol diet was decreased up to the levels of normal diet group according to WJ diet. The results indicated that WJ possesses antioxidant effects through free radical scavenging effects on DPPH, NO and the decreasing of XO activity. In view of these results, WJ is expected to be an effective material for the anti-oxidant.

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Consideration of The back side reflector for LED Lighting Fixture (LED 조명기구의 후면 반사판 부착에 대한 고찰)

  • Shin, S.W.;Lim, J.M.;Hwang, M.K.;Yi, C.W.
    • Proceedings of the Korean Institute of IIIuminating and Electrical Installation Engineers Conference
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    • 2008.05a
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    • pp.126-129
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    • 2008
  • 최근 들어 기존 조명기구를 대신하여 LED 조명기구가 크게 각광을 받고 있다. 이는 LED의 장점인 낮은 소비전력과 긴 수명 때문인 것으로 생각된다. 하지만, 빛을 확산시켜야 하는 조명관점에서 본다면 LED 조명기구에도 개선해야 할 부분도 많아지는 것도 사실이다. 본 논문에서는 LED 조명기구에서 빛의 확산을 위해 사용되어지는 고가의 반사판에 대해 실제 개발된 조명기구의 배광곡선 분석과 시뮬레이션을 통해 확산효과를 면밀히 분석함으로써 향후 LED 조명기구의 설계에 있어서 기술 및 경제적 관점에서 도움을 주고자 한다.

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Two-Dimensional Phase Retrieval Using Window Functions (윈도우 함수를 이용한 2차원 신호의 위상복원)

  • Kim, Woo-Shik
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.35S no.10
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    • pp.126-134
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    • 1998
  • In this paper, we consider the problem of reconstructing a two-dimensional signal from its Fourier intensity and the Fourier intensities of two windowed signals: one by a window w(m,n) and the other by its complementary window [1-w(m,n)]. We develop several conditions under which a signal can be uniquely specified to within several trivial ambiguities such as sign, translation,and time-reversal from the given conditions. We present two possible reconstruction algorithms derived from the Gerchberg-Saxton algorithm.

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Rack Power Solutions for Green Data Centers (그린 데이터센터를 위한 랙전원 솔루션)

  • Kwon, W.O.;Kim, S.W.
    • Electronics and Telecommunications Trends
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    • v.24 no.4
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    • pp.126-134
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    • 2009
  • 기존의 AC 전력전달 기반의 데이터센터를 고효율의 DC 데이터센터로 변경에 관한 연구가 활발히 진행중이다. 그 중 랙 준위 DC 전원공급장치는 기존 데이터센터의 전력구조 변화 없이 랙 레벨에서 DC 전원을 서버에 공급하는 방식으로 기존 AC 데이터센터에 적용 가능한 최적의 기술이다. 본 논문은 ETRI가 개발한 데이터센터의 랙 준위 DC 전원공급장치 특징에 관한 내용을 담고 있다. 본 장치는 부하에 따라 효율을 최적으로 제어하는 지능적 제어 기법을 사용하며, 랙 준위 N+ 1 전력 이중화로 높은 안정성을 제공하고 있다. 또한 랙 준위 전력 및 랙 주위 온/습도정보의 실시간 웹 모니터링 기능을 제공하고 있다.

Comparison of Measurement and Calculation Model of Solar Luminous Efficacy for All Sky Conditions in Seoul (천공구분에 따른 서울지역 일사의 발광효율 측정 및 예측모델과의 비교 연구)

  • Yoon, Kap-Chun;Yun, Gyeong;Kim, Kang-Soo
    • Journal of the Korean Solar Energy Society
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    • v.31 no.6
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    • pp.86-94
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    • 2011
  • For accurate dayligh tsimulation, accurate exterior illuminance is necessary. But, Korea Meteorological Agency provides only the solar irradiance data. Thus, there is a need for the research on luminous efficacy. In this study, global horizontal irradiance, diffuse horizontal irradiance, global horizontal illuminance, and diffuse horizontal illuminance were measured to calculate the luminous efficacy in SEOUL. And, we evaluated the applicability of the Perez's model by comparing the measured data and calculated data. As a result, measured global luminous efficacy is 126(110~129)lm/W and diffuse luminous efficacy is 127(115~133)lm/W in Seoul. Perez's model was relatively accurate with 5% difference in the diffuse luminous efficacy. But, it can be predicted about 15% lower in the global luminous efficacy.

Performance Analysis of mobile Relay Broadcasting with FPU system for Video Transmission (동영상 전송을 위한 이동형 방송중계용 FPU 전송시스템의 분석 및 성능 평가)

  • 조송백;김지웅;강희조;오창헌
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2004.05b
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    • pp.123-126
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    • 2004
  • 현재 방송중계용으로 쓰이는 주파수대는 3~30GHz의 M/W 대역이다. 그러나 갈수록 늘어나는 서비스와 전송용량의 증대로 인해 주파수 부족현상이 일어나는 추세이다. 이에 대안 방안으로 주파수 재배치에 관하여 대두가 되고 있다. 이동방송 중계용 링크인 FPU 링크는 차후 다른 주파수 대역으로 이전시 이러한 링크에서 사용되었던 시스템 제원을 토대로 필요한 대역에 대한 다양한 변조방식으로 먼저 시뮬레이션 평가 후 이용채널 개수 및 이전 가능 여부 둥과 같은 조치가 수행되어져야 한다. 본 논문에서는 M/W대역의 주파수를 이용한 서비스 중의 하나인 이동전송용 중계방송시스템인 FPU(Field Pick Up)시스템을 구현하고 무선채널에서 영상을 전송하였을 때의 성능을 PSNR, BER의 특성을 통하여 평가하였다. 전송되는 데이터는 실제 동영상(320$\times$240 61frame)을 동영상 압축방식 중 하나인 MPEG을 이용하여 압축하고, 압축된 영상 정보를 무선 채널상에 전송하였을 때 복원된 영상을 분석하였다.

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