• Title/Summary/Keyword: Vomiting

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Nausea/Vomiting and Self-care in Patients with Cancer on Chemotherapy (항암화학요법환자의 오심.구토 및 자가간호 실태)

  • Kim Hye-Jin;Kim Hee-Seung
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.12 no.2
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    • pp.180-185
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    • 2005
  • Purpose: The purpose of this study was to investigate the incidence and self care practice for nausea/vomiting in patients with cancer during chemotherapy. Method: The participants were 100 patients with cancer over 20 years of age who visited the outpatient department or were hospitalized for chemotherapy Self care in the case of nausea and vomiting was measured by the Dodd's scale. Data were analyzed using the SAS program and the following statistics were used frequency, percentage, unpaired t test, and Pearson correlation coefficient. Results: The ratio of the occurrence of nausea/ vomiting in the participants was 70.0%. The incidence of nausea/ vomiting was significantly higher for women than for men. The incidence of nausea/ vomiting was also higher for patients with cancer not in the gastro-intestinal system (GIS) compared to that for patients with GIS cancer. The incidence of nausea/ vomiting positively correlated with anorexia, skin injury, and fatigue. Conclusion: The ratio of occurrence of nausea/ vomiting for the participants was 70.0%. The incidence of nausea/ vomiting was higher fur women and patients with cancer not in the GIS. The incidence of nausea/ vomiting positively correlated with anorexia, skin injury, and fatigue. The results indicate that nausea/vomiting is a frequent symptom, particularly in women and there is a need to provide interventions to decrease the effects of this symptom.

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A Case of Metastatic Brain Tumor Patient with Nausea and Vomiting Treated with Gamibokryungbanha-tang (전이성 뇌종양 환자에게 발생한 오심(惡心), 구토(嘔吐)에 대해 가미복령반하탕으로 호전된 치험 1례)

  • Jeong, Jong-Soo;Park, Jae-Woo;Yoon, Seong-Woo
    • The Journal of Internal Korean Medicine
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    • v.28 no.4
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    • pp.956-962
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    • 2007
  • In cancer patients showing nausea and vomiting, a number of factors can be considered as the cause including brain tumor, electrolyte imbalance, gastrointestinal diseases or types of chemotherapy agents and dose of the drugs. Though nausea and vomiting can be minimized through the use of various anti-emetic drugs, many people still suffer from severe nausea and vomiting with poor quality of life compared with patients who do not show significant nausea and vomiting. In this report, we introduce a case of a cancer patient who suffered from severe nausea and vomiting. The patient was female and 59 years old with NSCLC (non small cell lung cancer) with metastatic brain tumor. Though western conventional medical treatment was used to reduce the symptoms, persistent nausea and vomiting were noted during the admission period. Herbal decoction Gamibokryungbanha-tang was used for nausea and vomiting which were uncontrolled under conventional western medicine; the patient showed remarkable improvement in terms of frequency and severity of nausea and vomiting. Further study will be needed in order to determine the long-term effectiveness of oriental medical treatment on cancer patient with nausea and vomiting.

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Psychiatric Treatment of Ruminative Vomiting and the Associated Weight Loss in an Adolescent Boy with Autism : A Case Report (자폐증 청소년에서 체중감소와 연관된 반추적 구토의 정신과적 치료)

  • Shin, Yun-O;Rhee, Moon-Sung
    • Journal of the Korean Academy of Child and Adolescent Psychiatry
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    • v.20 no.1
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    • pp.39-43
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    • 2009
  • We treated the persistent ruminative vomiting of a 13-year-old autistic boy by using a behavioral and psychopharmacological approach in a closed ward. Before the interventions, the patient had lost about 10kg of body weight due to very high-frequency ruminative vomiting. Together with psychopharmacological trials, the psychiatric treatment included a combination of a behavioral approach and food regulation that emphasized food restrictions, and we provided regular light meals. There was a considerable reduction of the ruminative vomiting and 2kg weight gain was achieved during the admission. These therapeutic gains were maintained at the 4-month follow-up assessment and the vomiting symptom reached a near-zero level and the weight loss were recovered by about 8kg. The issues related to the treatment approaches for ruminative vomiting with autism are discussed.

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The Study on 5 cases of Patient with Vomiting and Nausea (이침요법을 시행한 오심구토 환자 5례의 임상고찰)

  • Han Seung-Hea;Kim Yong-Ho;Seo Ho-Seok;Hwang Gyu-Dong;Jung Hyo-Chang;Son Ji-Hyung;Lee Seung-Hyun
    • The Journal of Internal Korean Medicine
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    • v.24 no.4_2
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    • pp.1023-1029
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    • 2003
  • Objective: The purpose of this study is to inspect recovery state of patients suffering from nausea and vomiting, who received auricular acupuncture. On the other hand, we are going to examine effects of auricular acupuncture through the study of treatises on nausea and vomiting. Nausea and vomiting are ordinary symptoms of dispositional or functional disease. The symptoms often appear without obvious disorders that can be detected on various inspection. Methods: Auricular acupuncture needling was given to the patients who had reported the symptoms of nausea and vomiting. They were hospitalized at the korean oriental internal medicine of National Medical Center from Dec. 2002 to Aug. 2003. Result: Relatively quick response of treatment was acquired after auricular acupuncture on nausea and vomiting. Conclusion: This study shows that auricular acupuncture is effective in reducing nausea and vomiting without regard to causal disease.

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Aprepitant in the Prevention of Vomiting Induced by Moderately and Highly Emetogenic Chemotherapy

  • Wang, Shi-Yong;Yang, Zhen-Jun;Zhang, Zhe;Zhang, Hui
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.23
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    • pp.10045-10051
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    • 2015
  • Chemotherapy is a major therapeutic approach for malignant neoplasms; however, due to the most common adverse events of nausea and vomiting, scheduled chemotherapeutic programs may be impeded or even interrupted, which severely impairs the efficacy. Aprepitants, 5-HT3 antagonists and dexamethasone are primary drugs used to prevent chemotherapy-induced nausea and vomiting (CINV). These drugs have excellent efficacy for control of acute vomiting but are relatively ineffective for delayed vomiting. Aprepitant may remedy this deficiency. Substance P was discovered in the 1930s and its association with vomiting was confirmed in the 1950s. This was followed by a period of non-peptide neurokinin-1 (NK-1) receptor antagonist synthesis and investigation in preclinical studies and clinical trials (phases I, II and III). The FDA granted permission for the clinical chemotherapeutic use of aprepitant in 2003. At present, the combined use of aprepitant, 5-HT3 antagonists and dexamethasone satisfactorily controls vomiting but not nausea. Therefore, new therapeutic approaches and drugs are still needed.

Effects of the Nei-Guan (P6) Acupressure on Nausea, Vomiting, and Pain in Geriatric Patients after Total Knee Replacement Arthroplasty (내관지압이 슬관절 전치환술 받은 노인 환자의 오심, 구토 및 통증에 미치는 효과)

  • Yoo, Je-Bog;Jang, Hee-Jung;Na, Eun-Hee;Kim, Sun-Young;Shin, Dong-Soo
    • Journal of East-West Nursing Research
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    • v.17 no.2
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    • pp.96-102
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    • 2011
  • Purpose: Patient-controlled epidural analgesia (PCEA) is an effective method for controlling post surgical pain. However, it is associated with adverse drug reactions such as nausea and vomiting. In this, study we tested the effects of Nei-Guan (P6) acupressure on PCEA-associated nausea, vomiting, and pain in geriatric patients after total knee replacement arthroplasty (TKRA). Methods: Ninety-nine patients who had TKRA for the first time were randomly assigned to either, experiment group (n=50) or control groups (n=49). All patients received PCEA immediately after surgery, but acupressure on Nei-Guan (P6) point was applied to experiment group only. Ten minutes of finger acupressure on Nei-Guan (P6) acupressure point was applied twice with 15 minute-interval in the experiment group. The incidence of nausea, vomiting, and retching as well as pain intensity were assessed at 12 and 24 hours after surgery. Nausea, and vomiting were assessed by Index of Nausea, Vomiting and Retching (INVR) questionnaire. Pain intensity was measured with frequency of analgesics. Results: Vomiting both was significantly different between two groups at 12 hours (t=-2.18, p=0.03) and 24 hours (t=-2.64, p=0.01) after surgery. Total scores of nausea, vomiting and retching in experimental group was significantly lower than control group 24hours after surgery (t=-2.18, p=0.03). However, pain was not different between two groups. Conclusion: Nei-Guan (P6) acupressure may be considered as an effective nursing intervention to decrease PCEA-associated nausea and vomiting in older patients after TKRA.

Evaluation of Antiemetic Therapy for Breakthrough Nausea and Vomiting in Patients with Hematopoietic Stem Cell Transplantation (조혈모세포 이식 환자의 돌발성 구역·구토에 대한 항구토제 사용 현황)

  • Kim, Jiyoon;Hong, So Yeon;Jeon, Su Jeong;Namgung, Hyung Wook;Lee, Eun Sook;Lee, Euni;Bang, Soo-Mee
    • Korean Journal of Clinical Pharmacy
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    • v.28 no.3
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    • pp.224-229
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    • 2018
  • Background: The patients receiving hematopoietic stem cell transplantation (HSCT) are known to have a high incidence of breakthrough nausea and vomiting due to the conditioning regimen. The purpose of this study was to evaluate the adequacy of antiemetic therapy for breakthrough nausea and vomiting in patients receiving HSCT and to propose an effective treatment regimen. Methods: We retrospectively reviewed the electronic medical records of 109 adult patients. The collected data were used to identify (1) antiemetic and dosing regimens prescribed for controlling breakthrough nausea and vomiting, (2) the rate of patients who developed breakthrough nausea and vomiting, and (3) the percent of antiemetics prescribed on the day of symptom onset. Based on the National Comprehensive Cancer Network guideline, we assessed the suitability of antiemetics for breakthrough nausea and vomiting, and prescription timing. Results: All patients were prescribed pro re nata antiemetics. About 40.0%, 41.4%, and 18.6% of patients were using one, two, and three or more additional drugs for breakthrough nausea and vomiting, respectively. The most frequently administered drugs were intravenous metoclopramide (43.8%) and granisetron patch (36.2%). Breakthrough nausea and vomiting occurred in 87 patients (79.1%) and they developed symptoms 320 cases. About 220 cases (68.8%) were treated with additional antiemetics on the day of symptom onset and the rate of symptom resolution was only 10.3% (9 patients). Conclusion: The breakthrough nausea and vomiting in patients receiving HSCT occurred very frequently and was hard to control, thus requiring more rapid and aggressive treatments.

Comparison of Effects of Different Acupressure Methods on Nausea, Vomiting, and Anorexia for Breast Cancer Patients: Among Patients Undergoing Chemotherapy (항암화학요법을 받고 있는 유방암 환자에서 내관지압 방법에 따른 오심, 구토, 식욕부진의 효과 비교)

  • Park, Hyo-Sun;Shin, Na-Yeon
    • Journal of Korean Biological Nursing Science
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    • v.22 no.2
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    • pp.102-110
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    • 2020
  • Purpose: The purpose of the study was to identify the comparison with the different methods of acupressure treatment in breast cancer patients undergoing chemotherapy. Methods: This study was a single group pretest-posttest design. Thirty patients age 30-65 scheduled for chemotherapy were included. The data were collected through self- reported questionnaires on nausea, vomiting, and anorexia and analyzed using descriptive statistics and the Wilcoxon signed ranked test. Results: The relieving effect of nausea and vomiting (Z= -2.54, p= .011) was significant in P6 acupressure by wrist bands. Conclusion: Patients undergoing chemotherapy have relieving effects on nausea and vomiting after P6 acupressure by wrist band. This study demonstrates the stimulation of the P6 acupressure by wrist band for reducing nausea and vomiting for breast cancer patients undergoing chemotherapy.

A Case Report of Cyclic Vomiting Syndrome in childhood by Sasang Constitution (주기성 구토 증후군 환아에 대한 증례보고)

  • Lee, Ji-Young;Jeong, Min-Jeong;Lee, Seung-Yeon
    • The Journal of Pediatrics of Korean Medicine
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    • v.20 no.1
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    • pp.85-91
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    • 2006
  • Objectives : The objectives of this study is a case report of Cyclic Vomiting Syndrome in childhood Methods : We experienced a child who ha diagnosed as Cyclic Vomiting Syndrome. We treated the patient with herb medicine, acupuncture and alimentotherapy of Sasang Constitution. Results : After the treatment of oriental medicine, the patient recovered from Cyclic Vomiting. Conclusions : We report one case of Cyclic Vomiting Syndrome in childhood the recovered after the treatment of Sasang Constitution. We think that the more follow-up is needed.

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A Case Report of 1 Patient Complaining of Hyperemesis Gravidarium (임신오조(姙娠惡阻) 1例에 대한 임상보고)

  • Park, Jun-Sik;Lim, Eun-Mee
    • The Journal of Korean Obstetrics and Gynecology
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    • v.18 no.1
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    • pp.234-241
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    • 2005
  • Hyperemesis gravidarum is a severe and intractable form of nausea and vomiting in pregnancy. It is a diagnosis of exclusion and may result in weight loss; nutritional deficiencies; and abnormalities in fluids, electrolyte levels, and acid-base balance. The peak incidence is at 8-12 weeks of pregnancy, and symptoms usually resolve by week 16. Interestingly, nausea and vomiting of pregnancy is generally associated with a lower rate of miscarriage. The cause of severe nausea and vomiting in pregnancy has not been identified. Extreme nausea and vomiting may be related to elevated levels of estrogens or human chorionic gonadotropin. Once the diagnosis is made, treatment consists of mainly supportive care. Until vomiting is controlled, these patients should be maintained as NPO. We treated 1 patient who had hyperemesis gravidarum and visited Kyung-Won Incheon Oriental Hospital by Herbal medication, acupuncture, moxa and nega therapy and got good result from them.

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