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Anti-obesity effects of Tenebrio molitor larvae powder in high-fat diet-induced obese mice

  • Park, Bo Mi;Lim, Hyung Ju;Lee, Bong Joo
    • Journal of Nutrition and Health
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    • v.54 no.4
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    • pp.342-354
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    • 2021
  • Purpose: Obesity is a serious public health issue for the modern society and is considered a chronic health hazard. There are many surgical and pharmacological approaches to treat obesity. However, various potentially hazardous side effects remain the biggest challenge. Therefore, diets based on foods derived from natural products have gained increasing attention compared to anti-obesity drugs. Recently, research on edible insects as a food source has been a topic of considerable interest in the scientific communities. This study examined the anti-obesity effects of ingesting an edible insect by feeding a high-fat diet (HFD)-induced obese mouse models with a diet containing Tenebrio molitor larvae powder (TMLP). Methods: Six-week-old female C57BL/6J mice were divided into 4 groups according to treatment: 100% normal diet (ND), 100% HFD (HFD), HFD 99% + TMLP 1% (TMLP), and HFD 97% + TMLP 3% (TMLP 3%). TMLP was added to the HFD for 6 weeks for the latter two groups. Results: Compared to the HFD group, mice in the TMLP group showed weight loss, and micro-computed tomographic imaging revealed that the volume of the adipose tissue in the abdominal area also showed significant reduction. After an autopsy, the fat weight was found to be significantly reduced in the TMLP group compared to the HFD group. In addition, the degree of fat cell deposition in the liver tissue and the size of the adipocytes significantly decreased in the TMLP group. Reverse transcription polymerase chain reaction analysis for the mRNA expression of adipogenesis-related genes namely CCAAT-enhancer-binding proteins (C/EBP-β, C/EBP-δ), and fatty acid-binding protein 4 (FABP4) showed that the expression levels of these genes were significantly reduced in the TMLP group compared to the HFD group. Serum leptin level also decreased significantly in the TMLP group in the comparison with the HFD group. In addition, total cholesterol, triglyceride, and glucose levels in mouse serum also decreased in the TMLP group. Conclusion: Taken together, our results showed that TMLP effectively inhibited adipocyte growth and reduced body weight in obese mice.

FAST Design for Large-Scale Satellite Image Processing (대용량 위성영상 처리를 위한 FAST 시스템 설계)

  • Lee, Youngrim;Park, Wanyong;Park, Hyunchun;Shin, Daesik
    • Journal of the Korea Institute of Military Science and Technology
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    • v.25 no.4
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    • pp.372-380
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    • 2022
  • This study proposes a distributed parallel processing system, called the Fast Analysis System for remote sensing daTa(FAST), for large-scale satellite image processing and analysis. FAST is a system that designs jobs in vertices and sequences, and distributes and processes them simultaneously. FAST manages data based on the Hadoop Distributed File System, controls entire jobs based on Apache Spark, and performs tasks in parallel in multiple slave nodes based on a docker container design. FAST enables the high-performance processing of progressively accumulated large-volume satellite images. Because the unit task is performed based on Docker, it is possible to reuse existing source codes for designing and implementing unit tasks. Additionally, the system is robust against software/hardware faults. To prove the capability of the proposed system, we performed an experiment to generate the original satellite images as ortho-images, which is a pre-processing step for all image analyses. In the experiment, when FAST was configured with eight slave nodes, it was found that the processing of a satellite image took less than 30 sec. Through these results, we proved the suitability and practical applicability of the FAST design.

The Effects of Governance on Remittances: Evidence from Cross-Country Panel Data

  • Cho, Jung-Hwan
    • Journal of Korea Trade
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    • v.24 no.7
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    • pp.29-37
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    • 2020
  • Purpose - This paper empirically investigates the relationship between country governance quality and worker remittances from foreign countries. Because remittances can be a source of funds for economic development and smoothing economic crises in developing countries, the related topic has been a concern for policy-makers and academic researchers. This paper divides the motives of remittances into altruistic and investment motives through existing papers, and then considers the governance quality the remittance receiving country as one of the determinants of remittances. Design/methodology - Our empirical model considers whether governance quality can affect the volume of remittances, and uses altruistic and investment factors studied in the literature. To do this, a two-step approach is taken. First, the panel data are examined via pooled OLS, random effects, and Tobit estimation. Second, the paper reduces six governance indicators into one variable, Governance, using the principal component technique (PCA) for a robustness check. Findings - The main findings can be summarized as follows. The negative governance variable in the estimation results shows a lower governance quality that induces workers to send savings to their home countries. This means that a country with poor governance quality seems to have more remittance inflows from abroad. It also reveals that poor governance quality is more relevant to an altruistic motive rather than an investment motive, in general. The positive per capita GDP variable shows the investment motive for developed countries. Originality/value - Existing papers have focused on various factors related to the motives of remittances. However, governance quality effects on remittance inflows have not been fully studied so far. This paper considers governance quality in an estimation equation explicitly as one of the determinants of remittances. This area of study is needed, in theory and empirically, in order to fully understand the relationship between governance and remittances.

Secondary Neutron Dose in Carbon-ion Radiotherapy: Investigations in QST-NIRS

  • Yonai, Shunsuke;Matsumoto, Shinnosuke
    • Journal of Radiation Protection and Research
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    • v.46 no.2
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    • pp.39-47
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    • 2021
  • Background: The National Institutes for Quantum and Radiological Science and Technology-National Institute of Radiological Sciences (QST-NIRS) has continuously investigated the undesired radiation exposure in ion beam radiotherapy mainly in carbon-ion radiotherapy (CIRT). This review introduces our investigations on the secondary neutron dose in CIRT with the broad and scanning beam methods. Materials and Methods: The neutron ambient dose equivalents in CIRT are evaluated based on rem meter (WENDI-II) measurements. The out-of-field organ doses assuming prostate cancer and pediatric brain tumor treatments are also evaluated through the Monte Carlo simulation. This evaluation of the out-of-field dose includes contributions from secondary neutrons and secondary charged particles. Results and Discussion: The measurements of the neutron ambient dose equivalents at a 90#x00B0; angle to the beam axis in CIRT with the broad beam method show that the neutron dose per treatment dose in CIRT is lower than that in proton radiotherapy (PRT). For the scanning beam with the energy scanning technique, the neutron dose per treatment dose in CIRT is lower than that in PRT. Moreover, the out-of-field organ doses in CIRT decreased with distance to the target and are less than the lower bound in intensity-modulated radiotherapy (IMRT) shown in AAPM TG-158 (American Association of Physicists in Medicine Task Group). Conclusion: The evaluation of the out-of-field doses is important from the viewpoint of secondary cancer risk after radiotherapy. Secondary neutrons are the major source in CIRT, especially in the distant area from the target volume. However, the dose level in CIRT is similar or lower than that in PRT and IMRT, even if the contributions from all radiation species are included in the evaluation.

Electrochemical Properties of Tin-Antimony Sulfide Nanocomposites Synthesized by Hydrothermal Method as Anode Materials for Sodium Ion Batteries (수열 합성법에 의해 제조된 주석-안티몬 황화물계 나노복합체 기반 나트륨이온전지용 음극의 전기화학적 특성)

  • So Hyeon Park;Su Hwan Jeong;Suyoon Eom;Sang Jun Lee;Joo-Hyung Kim
    • Korean Journal of Materials Research
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    • v.32 no.12
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    • pp.545-552
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    • 2022
  • Tin-antimony sulfide nanocomposites were prepared via hydrothermal synthesis and a N2 reduction process for use as a negative electrode in a sodium ion battery. The electrochemical energy storage performance of the battery was analyzed according to the tin-antimony composition. The optimized sulfides exhibited superior charge/discharge capacity (770 mAh g-1 at a current density of 100 mA g-1) and stable lifespan characteristics (71.2 % after 200 cycles at a current density of 500 mA g-1). It exhibited a reversible characteristic, continuously participating in the charge-discharge process. The improved electrochemical energy storage performance and cycle stability was attributed to the small particle size, by controlling the composition of the tin-antimony sulfide. By optimizing the tin-antimony ratio during the synthesis process, it did not deviate from the solubility limit. Graphene oxide also acts to suppress volume expansion during reversible electrochemical reaction. Based on these results, tin-antimony sulfide is considered a promising anode material for a sodium ion battery used as a medium-to-large energy storage source.

A ramus cortical bone harvesting technique without bone marrow invasion

  • Jeong-Kui Ku;Min-Soo Ghim;Jung Ho Park;Dae Ho Leem
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.49 no.2
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    • pp.100-104
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    • 2023
  • Autogenous bone grafts from the mandibular ramus are a known source of inadequate bone volume scenarios of the residual alveolar ridge. However, the conventional block-type harvesting technique cannot prevent bone marrow invasion, which can cause postoperative complications such as pain, swelling, and inferior alveolar nerve injury. This study aims to suggest a complication-free harvesting technique and present the results of bone grafting and donor sites. One patient received two dental implants with a complication-free harvesting technique that involves creation of ditching holes with a 1 mm round bur. Sagittal, coronal, and axial osteotomies produced grid-type cortical squares using a micro-saw and a round bur to confirm the cortical thickness. The grid-type cortical bone was harvested from the occlusal aspect, and the harvesting was extended through an additional osteotomy on the exposed and remaining cortical bone to prevent bone marrow invasion. The patient did not suffer postoperative severe pain, swelling, or numbness. After 15 months, the harvested site exhibited new cortical bone lining, and the grafted area had healed to a cortico-cancellous complex with functional loading of the implants. Our technique, grid-type cortical bone harvesting without bone marrow invasion, allowed application of autogenous bone without bone marrow invasion to achieve acceptable bone healing of the dental implants and to regenerate the harvested cortical bone.

A Study on Acquisition of Overhead Line Location Information of Pantograph for E-Highway (E-Highway를 위한 팬터그래프의 가공선 위치정보 취득에 관한 연구)

  • Gwang-Cheol Song;Jun-Jae An;Tuan-Vu Le;Seong-Mi Park;Sung-Jun Park
    • Journal of the Korean Society of Industry Convergence
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    • v.26 no.5
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    • pp.915-923
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    • 2023
  • As environmental regulations on carbon emissions are strengthened worldwide, the existing internal combustion engine-centered automobile industry is being reformed. In particular, large buses and large cargo trucks are pointed out as one of the main causes of environmental destruction due to excessive carbon emissions. The E-Highway power collection system, which has recently been proposed as a solution, uses the vehicle's battery as a backup power source or regenerative braking, depending on whether the pan head of the pentograph installed in the vehicle is in contact with the overhead line. It is used to store the excess energy generated. However, wear through contact due to continuous contact reduces the current collection effect and causes failure. In this paper, by using the current difference, the horizontal position information of the panhead in contact with the overhead line is acquired, thereby reducing the abrasion of the conductor and the panhead Make it possible to follow the overhead line. The position estimation method proposed in this paper simply configures a device that can detect the position of the overhead line of the pantograph by the difference in resistance. It is economical and has the advantage of reducing the volume. The characteristics of the pantograph estimating the location of overhead lines were analyzed using the difference between the two currents of the current collector, the feasibility of the positioning estimation system was verified through simulations and experiments.

Study of injection molded pattern transferability of double-sided micro-patterned automotive thick light guides (양면 마이크로 패턴 차량용 후육 라이트 가이드의 사출성형 패턴 전사성에 관한 연구)

  • Dong-won Lee;Sang-Yoon Kim;Ji-Woo Kim;Jong-Su Kim;Sung-Hee Lee
    • Design & Manufacturing
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    • v.17 no.4
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    • pp.42-51
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    • 2023
  • In this study, we investigated the injection molding technology of thick-walled light guides, which are parts that control the light source of automotive lamps. Through injection molding analysis, the gate position that can minimize product shrinkage and deformation was selected, and a mold reflecting the analysis results was manufactured to evaluate the effect of injection speed and holding pressure on transferability during micro-pattern molding through experiments. When designing an injection mold for products with varying thicknesses, it was found that installing the gate on the side of the thicker part was advantageous for reducing volume shrinkage and deformation. It was found that the effect of shrinkage due to thickness may be greater than the position of the gate on pattern transferability. The pattern transfer error decreased as the injection speed and holding pressure increased, and it was found that increasing the injection speed was relatively effective.

A Study of Cesium Removal Using Prussian Blue-Alginate Beads (프러시안 블루-알지네이트 비드를 이용한 세슘 제거 연구)

  • So-on Park;Su-jung Min;Bum-kyoung Seo;Chang-hyun Roh;Sang-bum Hong
    • Journal of Radiation Industry
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    • v.18 no.1
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    • pp.89-93
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    • 2024
  • Accidents at nuclear facilities and nuclear power plants led to leaks of large amounts of radioactive substances. Of the various radioactive nuclides released, 137Cs are radioactive substances generated during the fission of uranium. Therefore, due to the high fission yield (6.09%), strong gamma rays, and a relatively long half-life (30 years), a rapid and efficient removal method and a study of adsorbents are needed. Accordingly, an adsorbent was prepared using Prussian blue (PB), a material that selectively adsorbs radioactive cesium. As a result of evaluating the adsorption performance with the prepared adsorbent, it was confirmed that 82% of the removal efficiency was obtained, and most of the cesium was rapidly adsorbed within 10 to 15 minutes. The purpose of this study was to adsorb cesium using the Prussian blue alginate bead and to compare the change in detection efficiency according to the amount of adsorbent added for quantitative evaluation. However, in this case, it is difficult to determine the detection efficiency using a standard source with the same conditions as the measurement sample, so the efficiency change of the HPGe detector according to the different heights of Prussian blue was calculated through MCNP simulation using certified standard materials (1 L, Marinelli beaker) for radioactivity measurement. It is expected to derive a relational equation that can calculate detection efficiency through an efficiency curve according to the volume of Prussian blue, quantitatively evaluate the activity at the same time as the adsorption of radioactive nuclides in actual contaminated water and use it in the field of nuclear facility operation and dismantling in the future.

Investigation of dry dog food market trends and valuation of carbohydrate sources for dog diets

  • Hyun-Woo Cho;Kangmin Seo;Min Young Lee;Ki Hyun Kim;Ju Lan Chun
    • Korean Journal of Agricultural Science
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    • v.50 no.3
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    • pp.449-458
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    • 2023
  • Plant-based, grain-free, and gluten-free diets have been the focus of recent research, as part of the premiumization trend in dog food. However, the lack of comprehensive information regarding carbohydrates in dog food makes it difficult to produce nutritionally balanced meals. Therefore, we aimed to evaluate the nutritional value of carbohydrate ingredients commonly used in commercial dog foods. First, using data from Euromonitor, we investigated the trends in the dry dog food industry and analyzed the annual volume of dry dog food sales, as well as the dog population from 2010 to 2021 in Korea. The growth of the market was greatest in 2021, when the total value of sales of premium dry dog food was 254.3 billion KRW (Korean won) more than in 2010. In addition, sales of dry dog food by age category were marked by a significant increase (404.8%) in the market for dry food for senior dogs. Second, we examined the frequency of carbohydrate ingredients used in dry dog food and conducted a proximate analysis of the top 10 most frequently used ingredients. Subsequently, we analyzed the crude protein, crude fat, and nitrogen-free extract in the carbohydrate ingredients based on dry matter (DM) and calculated the ratio of metabolic energy content supplied from each nutrient in the carbohydrate ingredients. The ratio of metabolic energy content in the carbohydrate ingredients indicated that mung beans had the highest crude protein content (31.3%), whereas oats exhibited the highest crude fat content (23.3%). Sweet potatoes had the highest nitrogen-free extract content, measuring at 93.6%. The results of this study are expected to provide a valuable foundation for the growth and development of the domestic dog food industry, while also contributing to a deeper understanding of the specific role of each ingredient as a carbohydrate source.