• 제목/요약/키워드: Volume of distribution

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The Effects of Information Volume and Distribution on Cognitive Load and Recall: Implications for the Design of Mobile Marker-less Augmented Reality

  • LIM, Taehyeong;BONG, Jiyae;KANG, Ji Hei;DENNEN, Vanessa
    • Educational Technology International
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    • v.20 no.2
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    • pp.137-168
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    • 2019
  • This study examined the effects of information volume and distribution on learners' cognitive load and recall in a mobile augmented reality (AR) environment. Information volume refers to the degree of information users are provided in a learning task, while information distribution indicates the way in which information is distributed, either in a virtual or real format. Sixteen undergraduate students participated in the study, which employed a 2 × 3 randomized block factorial design with repeated measures. Information volume and distribution were independent variables, and factors in learners' cognitive load (mental effort, perceived ease of use, and perceived task difficulty) and recall test scores were the dependent variables. Information volume had significant main effects on perceived ease of use and task difficulty, and recall test scores, while information distribution had significant main effects on perceived task difficulty and test scores. A detailed discussion and implications are provided.

Determination of Dosing Weight on Aminoglycosides (Aminoglycosides계 약물의 투약 체중 결정)

  • Lee, Rae Young;Kim, Ho Soon;Shin, Wan Gyoon;Cho, Nam Chun
    • Korean Journal of Clinical Pharmacy
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    • v.9 no.1
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    • pp.15-18
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    • 1999
  • Ascertainment of accurate pharmacokinetic parameters for aminoglycoside dosing remains critical, as the serum drug concentration relates directly to both the therapeutic response and toxic effect. In the initial dosing of aminoglycosides, the volume of distribution is especially important because the dosage is calculated by multiplying the volume of distribution by the desired serum concentration. Aminoglycosides distribute into mainly the extracellular fluid and it has been reported that the volume of distribution is 0.25 L/kg. Penetration of polar aminoglycosides into adipose tissue occurs to some extent, but varies according to the degree of obesity. Therefore, dosages may be overestimated or underestimated according to the type of the dosing weight in overweight or underweight patients. Prior investigations have suggested various dosing weights which are multiplied by the popular volume of distribution to calculate the total volume of distribution. Based on other investigations, we calculated a new dosing weight which was applicable to all patients regardless of obesity in order to use the popular volume of distribution. We estimated IBW+$0.414^{\ast}$(TBW-IBW) as a new dosing weight with the SAS program. A new dosing weight is similar to those of other studies which examined in morbidly obese patients. Consequently we suggests that the dosing weight reported in morbidly obese patients can be extended to a broader patients population. But we found that the volume of distribution per kilogram from our patients was significantly larger than that for foreign patients(0.343L/kg vs 0.25 L/kg)(Kor. J. Clin. Pharm. 1999; 9(1): 15-18)

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Material distribution optimization of 2D heterogeneous cylinder under thermo-mechanical loading

  • Asgari, Masoud
    • Structural Engineering and Mechanics
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    • v.53 no.4
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    • pp.703-723
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    • 2015
  • In this paper optimization of volume fraction distribution in a thick hollow cylinder with finite length made of two-dimensional functionally graded material (2D-FGM) and subjected to steady state thermal and mechanical loadings is considered. The finite element method with graded material properties within each element (graded finite elements) is used to model the structure. Volume fractions of constituent materials on a finite number of design points are taken as design variables and the volume fractions at any arbitrary point in the cylinder are obtained via cubic spline interpolation functions. The objective function selected as having the normalized effective stress equal to one at all points that leads to a uniform stress distribution in the structure. Genetic Algorithm jointed with interior penalty-function method for implementing constraints is effectively employed to find the global solution of the optimization problem. Obtained results indicates that by using the uniform distribution of normalized effective stress as objective function, considerably more efficient usage of materials can be achieved compared with the power law volume fraction distribution. Also considering uniform distribution of safety factor as design criteria instead of minimizing peak effective stress affects remarkably the optimum volume fractions.

Fundamental Study on The Heat Input Model of Hybrid Welding for The Finite Element Analysis (유한요소해석을 위한 하이브리드용접 입열모델 선정에 관한 기초적 연구)

  • 방한서;김영표
    • Proceedings of the KWS Conference
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    • 2003.11a
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    • pp.36-38
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    • 2003
  • In order to understand the basic knowledge on the model of heat source in hybrid welding, authors have conducted finite element analysis to calculate heat distribution using three heat source models of non-split type and split type(Volume, Volume-Volume, Volume-Surface). From the research result, we can confirm that Volume-Volume heat source of split type is suitable for the analysis of heat distribution.

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Developing a Method for Detecting the Asian dust event Among High $PM_{10}$ events Using Aerodynamic Particle Sizer (APS) (Aerodynamic Particle Sizer (APS)를 이용한 고농도 $PM_{10}$ 사례 중 황사 판별기법 개발)

  • Lee, Young-Gon;Cho, Chun-Ho;Kim, Myoung-Soo
    • Atmosphere
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    • v.18 no.1
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    • pp.25-32
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    • 2008
  • Log normalized volume size distribution (dV/dlog$D_p$) with 52 size ranges from 0.5 to $20.0{\mu}m$ was measured for the cases of high $PM_{10}$ mass concentration (> $200{\mu}gm^{-3}$) using the Aerodynamic Particle Sizer (APS) at the Korea Global Atmosphere Watch Center (KGAWC) from 6 April, 2006 to 5 April, 2007. Black Carbon (BC), gaseous pollutants of $NO_X$ and $SO_2$ and ${\AA}ngstr\ddot{o}m$ exponent were also measured to examine the properties of the volume size distribution. From distinct difference of the high volume concentration (> $100{\mu}m^3cm^{-3}$), the volume size distribution for each event day was clasified into four types: (1) Type 1 had the high volume concentration for supermicron particles from 2.3 to $6.0{\mu}m$ and maximum average volume concentration was $160.7{\mu}m^3cm^{-3}$ at $3.5{\mu}m$. (2) Type 2 represented the high volume concentration in the both size range of submicron ($0.7-1.0{\mu}m$) and supermicron particles ($2.1-4.1{\mu}m^3cm^{-3}$ and $136.2{\mu}m^3cm^{-3}$ were found at 0.8 and $3.3{\mu}m$ respectively. (3) Type 3 showed the high volume concentration in the size range of $0.5-3.5{\mu}m$ and highest volume concentration of $201.1{\mu}m^3cm^{-3}$ at the particle size bin of $0.8{\mu}m$. (4) Type 4 was characterized by the high volume concentration for the fine particles less than $1.2{\mu}m$ and very high concentration of $446.8{\mu}m^3cm^{-3}$. ${\AA}ngstr\ddot{o}m$ exponent, concentration of gaseous ($NO_X$ and $SO_2$), and particle (BC) pollutants suggested that Type 1 was a typical volume size distribution for the Asian dust and Type 3 provided transportation of air pollutants. The distribution in Type 2 found to have both characteristics of the Asian dust and air pollutants, and Type 4 was took place during the foggy atmosphere containing high density of local pollutants. Based on the properties of volume size distribution, we can identify the three major events contributing the increase of $PM_{10}$ mass concentration, and hope to provide a guideline for discriminating the Asian dust from high $PM_{10}$ events. More case studies and longeto advance this determination method.

A Study on Reversals after Stock Price Shock in the Korean Distribution Industry

  • Jeong-Hwan, LEE;Su-Kyu, PARK;Sam-Ho, SON
    • Journal of Distribution Science
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    • v.21 no.3
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    • pp.93-100
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    • 2023
  • Purpose: The purpose of this paper is to confirm whether stocks belonging to the distribution industry in Korea have reversals, following large daily stock price changes accompanied by large trading volumes. Research design, data, and methodology: We examined whether there were reversals after the event date when large-scale stock price changes appeared for the entire sample of distribution-related companies listed on the Korea Composite Stock Price Index from January 2004 to July 2022. In addition, we reviewed whether the reversals differed depending on abnormal trading volume on the event date. Using multiple regression analysis, we tested whether high trading volume had a significant effect on the cumulative rate of return after the event date. Results: Reversals were confirmed after the stock price shock in the Korean distribution industry and the return after the event date varied depending on the size of the trading volume on the event day. In addition, even after considering both company-specific and event-specific factors, the trading volume on the event day was found to have significant explanatory power on the cumulative rate of return after the event date. Conclusions: Reversals identified in this paper can be used as a useful tool for establishing a trading strategy.

In vitro Estimation of The Hounsfield Units and The Volume and Void of Canine Struvite Stones as Predictors of Fragility in Extracorporeal Shock Wave Lithotripsy

  • Wang, Ji-hwan;Hwang, Tae-sung;Jung, Dong-in;Yeon, Seong-chan;Lee, Hee-chun
    • Journal of Veterinary Clinics
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    • v.34 no.3
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    • pp.178-184
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    • 2017
  • The aim of this study was to determine whether Hounsfield units (HUs), volume, and various void parameters can predict stone fragility in extracorporeal shock wave lithotripsy (ESWL). HU, volume, porosity, number of voids/stone volume, and void distribution of 30 struvite stones were estimated using helical computed tomography (CT) and micro-CT. The number of shock waves necessary for full fragmentation was accepted as a measure of the stone fragility in ESWL. The correlations between the number of shock waves and the HU, volume, porosity, and number of voids/stone volume were examined. The number of shock waves of the two groups according to the void distribution was also compared. Stone volume correlated with the number of shock waves. Shell-patterned struvite stones were significantly less susceptible to fragmentation in ESWL than non-shell-patterned struvite stones. Stone volume and void distribution may be predictors of the outcome of ESWL treatment.

Critical buckling analyses of nonlinear FG-CNT reinforced nano-composite beam

  • Zerrouki, Rachid;Karas, Abdelkader;Zidour, Mohamed
    • Advances in nano research
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    • v.9 no.3
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    • pp.211-220
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    • 2020
  • This paper investigates the effect of linear and non-linear distribution of carbon nanotube volume fraction in the FG-CNTRC beams on the critical buckling by using higher-order shear deformation theories. Here, the material properties of the CNTRC beams are assumed to be graded in the thickness direction according to a new exponential power law distribution in terms of the carbon nanotube volume fractions. The single-walled carbon nanotube is aligned and distributed in the polymeric matrix with different patterns of reinforcement; the material properties of the CNTRC beams are described by using the rule of mixture. The governing equations are derived through using Hamilton's principle. The Navier solution method is used under the specified boundary conditions for simply supported CNTRC beams. The mathematical models provided in this work are numerically validated by comparison with some available results. New results of critical buckling with the non-linear distribution of CNT volume fraction in different patterns are presented and discussed in detail, and compared with the linear distribution. Several aspects of beam types, CNT volume fraction, exponent degree (n), aspect ratio, etc., are taken into this investigation. It is revealed that the influences of non-linearity distribution in the beam play an important role to improve the mechanical properties, especially in buckling behavior. The results show that the X-Beam configuration is the strongest among all different types of CNTRC beams in supporting the buckling loads.

Robust Ultrasound Multigate Blood Volume Flow Estimation

  • Zhang, Yi;Li, Jinkai;Liu, Xin;Liu, Dong Chyuan
    • Journal of Information Processing Systems
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    • v.15 no.4
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    • pp.820-832
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    • 2019
  • Estimation of accurate blood volume flow in ultrasound Doppler blood flow spectrograms is extremely important for clinical diagnostic purposes. Blood volume flow measurements require the assessment of both the velocity distribution and the cross-sectional area of the vessel. Unfortunately, the existing volume flow estimation algorithms by ultrasound lack the velocity space distribution information in cross-sections of a vessel and have the problems of low accuracy and poor stability. In this paper, a new robust ultrasound volume flow estimation method based on multigate (RMG) is proposed and the multigate technology provides detail information on the local velocity distribution. In this method, an accurate double iterative flow velocity estimation algorithm (DIV) is used to estimate the mean velocity and it has been tested on in vivo data from carotid. The results from experiments indicate a mean standard deviation of less than 6% in flow velocities when estimated for a range of SNR levels. The RMG method is validated in a custom-designed experimental setup, Doppler phantom and imitation blood flow control system. In vitro experimental results show that the mean error of the RMG algorithm is 4.81%. Low errors in blood volume flow estimation make the prospect of using the RMG algorithm for real-time blood volume flow estimation possible.

Monte Carlo Simulation of the Molecular Properties of Poly(vinyl chloride) and Poly(vinyl alcohol) Melts

  • Moon, Sung-Doo;Kang, Young-Soo;Lee, Dong-J.
    • Macromolecular Research
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    • v.15 no.6
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    • pp.491-497
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    • 2007
  • NPT Monte Carlo simulations were performed to calculate the molecular properties of syndiotactic poly(vinyl chloride) (PVC) and syndiotactic poly(vinyl alcohol) (PVA) melts using the configurational bias Monte Carlo move, concerted rotation, reptation, and volume fluctuation. The density, mean square backbone end-to-end distance, mean square radius of gyration, fractional free-volume distribution, distribution of torsional angles, small molecule solubility constant, and radial distribution function of PVC at 0.1 MPa and above the glass transition temperature were calculated/measured, and those of PVA were calculated. The calculated results were compared with the corresponding experimental data and discussed. The calculated densities of PVC and PVA were smaller than the experimental values, probably due to the very low molecular weight of the model polymer used in the simulation. The fractional free-volume distribution and radial distribution function for PVC and PVA were nearly independent of temperature.