• Proceedings of the KSME Conference
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• 2004.11a
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• pp.166-171
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• 2004

Since early 1950's fracture mechanics has brought significant impact on structural integrity assessment in a wide range of industries such as power, transportation, civil and petrochemical industries, especially in nuclear power plant industries. For the last two decades, significant efforts have been devoted in developing defect assessment procedures, from which various fitness-for-purpose or fitness-for-service codes have been developed. From another aspect, recent advances in IT (Information Technologies) bring rapid changes in various engineering fields. IT enables people to share information through network and thus provides concurrent working environment without limitations of working places. For this reason, a network system based on internet or intranet bas been appeared in various fields of business. Evaluating the integrity of structures is one of the most critical issues in nuclear industry. In order to evaluate the integrity of structures, a complicated and collaborative procedure is required including regular in-service inspection, fracture mechanics analysis, etc. And thus, experts in different fields have to cooperate to resolve the integrity problem. In this paper, an internet-based cooperative system for integrity evaluation system which adapts IT into a structural integrity evaluation procedure for reactor pressure vessel is introduced. The proposed system uses Virtual Reality (VR) technique, Virtual Network Computing (VNC) and agent programs. This system is able to support 3-dimensional virtual reality environment and to provide experts to cooperate by accessing related data through internet.

• Proceedings of the KIEE Conference
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• 1999.07b
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• pp.883-886
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• 1999

Recently, with the development of computer technology, field instrument and control system using in industrial fields have changed from mechanical, electrical systems to digital electronic systems. Distributed control system(DCS), control functions are dispersed for grading up reliability and informations are combined fur effective management has been developed and sold. As this system has been enlarged and complicated, it is difficult to testing the system and very important to verifing functions systematically. In this report, function test procedure which is performed spontaneously by domestic or foreign DCS manufacturer was searched and analyzed. As its results, the test procedure of DCS functions were proposed. The proposed procedure was applied to DCS being used for a thermal power plant. The function test for DCS requires continuous and dynamic input/output signals, therefore we proposed the method to compose virtual plant which simulate the DCS functions with. And we suggested the test procedure of each DCS function.

• Proceedings of the Korea Society for Simulation Conference
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• 2005.11a
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• pp.102-107
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• 2005

PMS(Plant Monitoring System) for simulation is the program for training that users such as instructor, operator, and supervisor can operate the plant virtually. Presented in this paper, are some lessons learned from implementation of PMS for simulation. First, this PMS fer simulation is based on LINUX instead of UNIX. These two OS(Operating System) have different platform and compiler version on it, so debugging needs to be done about variable defining part. Second, In LINUX system, the size of shared memory and message queue is already designated as a default value that user has to set up and use the RTAP DB. Third, to decrease the dummy data size, it has to be changed into binary formation. Lastly, PMS software for simulation provides several environments according to the command, so considered should be status monitoring, alarm, system organization, point and group monitoring, history storage and searching function.

• Journal of the Korean Society of Safety
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• v.31 no.3
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• pp.162-167
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• 2016

As the simple empirical and phenomenological model applied to the analysis of leakage and explosion of chemical substances does not regard numerous variables, such as positional density of installations and equipment, turbulence, atmospheric conditions, obstacles, and wind effects, there is a significant gap between actual accident consequence and computation. Therefore, the risk management of a chemical plant based on such a computation surely has low reliability. Since a process plant is required to have outcomes more similar to the actual outcomes to secure highly reliable safety, this study was designed to apply the CFD (computational fluid dynamics) simulation technique to analyze a virtual prediction under numerous variables of leakages and explosions very similarly to reality, in order to review the computation technique of the practical safety distance at a process plant.

• Bulletin of the Korean Chemical Society
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• v.30 no.5
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• pp.1152-1156
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• 2009

Silent information regulator 2 (Sir2) or sirtuins are NAD(+)-dependent deacetylases, which hydrolyze the acetyllysine residues. In mammals, sirtuins are classified into seven different classes (SIRT1-7). SIRT1 was reported to be involved in age related disorders like obesity, metabolic syndrome, type II diabetes mellitus and Parkinson’s disease. Activation of SIRT1 is one of the promising approaches to treat these age related diseases. In this study, we have used HipHop module of CATALYST to identify a series of pharmacophore models to screen SIRT1 enhancing molecules. Three molecules from Sirtris Pharmaceuticals were selected as training set and 607 sirtuin activator molecules were used as test set. Five different hypotheses were developed and then validated using the training set and the test set. The results showed that the best pharmacophore model has four features, ring aromatic, positive ionization and two hydrogen-bond acceptors. The best hypothesis from our study, Hypo2, screened high number of active molecules from the test set. Thus, we suggest that this four feature pharmacophore model could be helpful to screen novel SIRT1 activator molecules. Hypo2-virtual screening against Maybridge database reveals seven molecules, which contains all the critical features. Moreover, two new scaffolds were identified from this study. These scaffolds may be a potent lead for the SIRT1 activation.

• Journal of the Ergonomics Society of Korea
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• v.24 no.2
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• pp.71-77
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• 2005

In spite of the importance of nuclear power as one of major electric energies in Korea, the nuclear safety has become the most serious social issue in the operation of the nuclear power plant. In this paper, a virtual work simulation program was developed to predict exposure dose during radiation work in radwaste storage. The work simulation program was developed. using $Java ^{TM}$applet and VRML-virtual reality modeling language. A numerical algorithm to find the optimal work path which minimize exposure dose during the given work, was developed and exposure dose on the optimal work path was compared with that on the shortest path. Comparing with the shortest path for the given work, the predicted optimal path consumed longer work time by II% but reduced total exposure dose by 46%. The simulation result showed that the exposure dose depended on not only work time, but also the distance between the worker and the radiation source. The developed simulation program could be a useful tool for the planning of radioactive waste work to increase the radiation safety of workers.

• Bulletin of the Korean Chemical Society
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• v.33 no.3
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• pp.869-880
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• 2012

Identification of the selective chemical features for Aurora-B inhibitors gained much attraction in drug discovery for the treatment of cancer. Hence to identify the Aurora-B critical features various techniques were utilized such as pharmacophore generation, virtual screening, homology modeling, molecular dynamics, and docking. Top ten hypotheses were generated for Aurora-B and Aurora-A. Among ten hypotheses, HypoB1 and HypoA1 were selected as a best hypothesis for Aurora-B and Aurora-A based on cluster analysis and ranking score, respectively. Test set result revealed that ring aromatic (RA) group in HypoB1 plays an essential role in differentiates Aurora-B from Aurora-A inhibitors. Hence, HypoB1 used as 3D query in virtual screening of databases and the hits were sorted out by applying drug-like properties and molecular docking. The molecular docking result revealed that 15 hits have shown strong hydrogen bond interactions with Ala157, Glu155, and Lys106. Hence, we proposed that HypoB1 might be a reasonable hypothesis to retrieve the structurally diverse and selective leads from various databases to inhibit Aurora-B.

• Journal of the Korean Institute of Gas
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• v.21 no.5
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• pp.89-94
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• 2017

The VR(Virtuality Reality) technology provides very close experience to reality by stimulating humans' external recognition with artificial technologies. In order to overcome the limitation of real-environment training, VR is being applied in industry field as a key technology to prevent safety accident and its control procedure training. However, it is difficult to build VR-based training system because 3D modeling and software coding are necessary for materialization of VR environment demands of many development resource. In this research referring to VR based training content implementation, a method to utilizing VRDC(VR-based Dynamic visualization Component) is suggested and by applying it to plant safety training system, it was confirmed its practicality.

• Journal of the Korea Society for Simulation
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• v.17 no.4
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• pp.1-9
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• 2008

Proposed in the paper is an automated procedure to construct a plant model for PLC simulation. Since PLC programs only contain the control logic without the information on the plant model, it is necessary to build the corresponding plant model to perform simulation. Conventionally, a plant model for PLC simulation has been constructed manually, and it requires much efforts as well as the in-depth knowledge of simulation. As a remedy for the problem, we propose an automated procedure to generate a plant model from the symbol table of a PLC program. To do so, we propose a naming rule for PLC symbols so that the symbol names include enough information on the plant model. By analyzing such symbol names, we extract a plant model automatically. The proposed methodology has been implemented, and test runs were made.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1995.10a
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• pp.947-951
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• 1995

Cim realization for the machinery manufacturing plant has several problems such as a lack of the adaptibity for system integration of the production machines, a lack of the flexibility for the information flow and a lack of the interchangeability fot the variety of the interchange information. In the paper the development of VMD for the object oriented machine tool in Cim enviroment is accomplised. FOr this purpose VMD is constructed in PC with NT 3.51/OS enviroment by using the exculsive comunication board and PLC for the conventional CNC machine tool that VMD support is not available. And also RS232 interface between VMD and CNC's and DNC 2 comunication board supplied by FANUC for two types of CNC are used. This developed VMD is very useful for CIM construction in the shop floor having the multi-vendor CNC controllers.