• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제35권4호
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• pp.199-204
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• 2009

Purpose: The purpose of this study is to investigate the epithelial-mesenchymal transition (EMT) induced by Snail transcription factor and Snail-transfected in vivo tumors with histopathological features. Materials and methods: We induced in vivo xenografted tumorigenesis in the oral vestibules of nude mice by a Snail transfected HaCaT cell line and investigated morphological and immunohistochemical features in Snail expressive tumors. Results: We identified tumor masses in 14 out of 15 nude mice in the HaCaT-Snail cell inoculation group, but no tumors were present in any of the HaCaT cell inoculation group. Induced tumors showed features of poorly differentiated carcinoma with invasion to neighboring muscles and bones. The HaCaT-Snail tumors showed decreased expressions of E-cadherin and cytokeratin, but showed increased expressions of vimentin and N-cadherin. Discussion: The Snail transfected xenograft can improve productivity of malignant tumors, show various histopathological features including invasive growth, and aid in the investigation of tumor progression and the interaction with surrounding tissues.

• 설비공학논문집
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• 제17권9호
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• pp.863-872
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• 2005

It is important to control indoor environment for influence on health and comfort of occupants in large-sized discount stores. On the other hand large-sized discount stores have a large number of visitors, vestibules, open spaces, high energy consumption and increasing of outside air intake. This study aims to offer the design data of building services system that can save energy and control environment through field measurement selecting two large-sized discount stores. Indoor environment factors such as temperature, relative humidity, air velocity and concentrations of $CO_2$, CO gas and TSP were measured and evaluated. In each case of $CO_2$, and CO gas, its maximum values were 2,800 ppm and 20 ppm. So proper strategy for the indoor air quality is indispensable in this type of building. Dry bulb temperature varies from $18^{\circ}C$ to $28^{\circ}C$ according to a measuring point and time. From this results, it is inferred these buildings had excessive equipment capacity. In terms of economical and environmental points, these data will be utilized to the design of HVAC system of retail facilities.

• 대한치과보철학회지
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• 제39권3호
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• pp.282-296
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• 2001

The accuracy of master cast reproduction by a polyvinylsiloxane impression material using two visible-light curing resin and autopolymerizing polymethyl methacrylate resin custom tray material was investigated. Custom trays were fabricated from a master cast that had three index points marked on both inner and outer vestibules and then poured in yellow stone. The distance between the reproduced index points were measured to be ${\pm}0.001mm$ with a measuring microscope and the algebraic norms calculated for each tray material. No differences were found in the algebraic norms of inner and outer dimensions for upper tray impressions by ANOVA(p>0.05). However, T-test revealed that there were differences between upper and lower impressions and Tukey's hsd test revealed that in lower tray impressions, the Palatray in inner, the Lightplast in outer dimensions respectively were different from other materials. The index points reproduced on the casts compared with the master cast, were closer together for upper tray impressions. All four tray materials produced acceptable casts, 1. Algebraic norms of inner and outer dimensions of the test casts for upper trays were not statistically different irrespective of materials.(P>0.05) 2. T-test showed that there were differences between means with upper and lower trays especially in outer dimension.(P>0.05) 3. But, algebraic norms of inner and outer dimensions of the test casts for lower trays were statistically different between materials. 4. Palatray XL in inner, Lightplast-platten in outer dimensions respectively for lower trays were different from other materials, but, the nearest to the original model.

• 대한치과보철학회지
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• 제60권4호
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• pp.404-411
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• 2022

본 증례의 환자는 80세 여성으로 #16, 13, 26, 37, 36, 35, 44, 45, 46, 47 치아가 상실되었으며, 하악 구치부의 결손으로 상실된 구치부 지지와 감소한 수직교합고경 및 전치부의 심한 수직피개를 보였다. 심미 및 기능상의 불편을 호소하였고, 보철치료를 통한 정상적인 안모 및 저작기능 회복을 주소로 내원하였다. 임상 소견, 방사선 검사, 안모 및 구내 분석 등을 시행하였다. 교합안정공극은 평균보다 과도하였고 상하악 전치 치은연 사이 거리 및 상하악 순측 전정 사이 거리, 하안면의 비율은 부족하여 수직고경 증가가 필요한 경우로 판단하였다. 소구치부 기준 약 4 mm의 수직고경 거상을 통한 교합 회복을 결정하였다. 본 증례에서는 구치부를 상실하여 전치부의 deep bite 및 수복공간의 부족을 보이는 환자에서 수직고경 거상 및 고정성, 가철성 보철물을 이용한 수복으로 안정된 교합관계 및 전방, 측방유도를 형성하여 환자의 심미적, 기능적인 수복 결과를 이끌어냈기에 이를 보고하는 바이다.