• Title/Summary/Keyword: Vero cell model

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Evaluation of the Antioxidant Efficacy of Padina boryana Extract from Maldivian Seaweed from Laccadive Sea Area (라카디브 해역 몰디브 자생 해조류 Padina boryana 추출물의 항산화 효능 평가)

  • Kim, Hyun-Soo;Wang, Lei;Jayawardena, Thilina U.;Lee, Jeong Min;Yim, Mi-Jin;Ko, Seok-Chun;Lee, Hyo-Geun;Je, Jun-Geon;Jeon, You-Jin;Lee, Dae-Sung
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.54 no.2
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    • pp.162-169
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    • 2021
  • Global warming has affected the distribution of organisms for decades and has displayed rapid ascent recently. Research into the effects on tropical organisms are vital. Padina boryana is a resourceful marine microalgae in the Maldives Sea in the Laccadive region. A 70% ethanol extraction (PBE) of this seaweed was used to investigate its antioxidant potential. Both in vitro and in vivo models were implemented. PBE exhibited protective potential against H2O2 induced apoptosis. ROS levels were suppressed due to PBE. PBE expressed a cytoprotective nature. In vivo experiments involving the zebra fish model conformed its validity. The antioxidant efficacy of PBE was dose dependent. Study outcomes suggest PBE has potential as a novel and valuable marine resource to aid the functional food and cosmeceutical industries.