• Title/Summary/Keyword: Variant

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Current Status and Future Challenges of the National Population Projection in South Korea Concerning Super-Low Fertility Patterns (국제비교를 통해 바라본 한국의 장래인구추계 현황과 전망)

  • Jun, Kwang-Hee;Choi, Seul-Ki
    • Korea journal of population studies
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    • v.33 no.2
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    • pp.85-111
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    • 2010
  • South Korea has experienced a rapid fertility decline and notable mortality improvement. As the drop in TFR was quicker and greater in terms of tempo and magnitude, it cast a new challenge of population projection - how to improve the forecasting accuracy in the country with a super-low fertility pattern. This study begin with the current status of the national population projection as implemented by Statistics Korea by comparing the 2009 interim projection with the 2006 official national population projection. Secondly, this study compare the population projection system including projection agencies, projection horizons, projection intervals, the number of projection scenarios, and the number of assumptions on fertility, mortality and international migration among super-low fertility countries. Thirdly we illustrate a stochastic population projection for Korea by transforming the population rates into one parameter series. Finally we describe the future challenges of the national population projection, and propose the projection scenarios for the 2011 official population projection. To enhance the accuracy, we suggest that Statistics Korea should update population projections more frequently or distinguish them into short-term and long-term projections. Adding more than four projection scenarios including additional types of "low-variant"fertility could show a variety of future changes. We also expect Statistics Korea topay more attention to the determination of a base population that should include both national and non-national populations. Finally we hope that Statistics Korea will find a wise way to incorporate the ideas underlying the system of stochastic population projection as part of the official national population projection.

Molecular epidemiological study of norovirus gastroenteritis outbreaks in Gyeonggi-Do from 2014 to 2015 (2014-2015년 경기지역 노로바이러스성 식중독의 분자역학적 특성분석)

  • Nam, Soo-Jung;Park, Po-Hyun;Bang, Sun-Jae;Huh, Jeong-Weon;Yun, Hee-Jeong;Park, Kwang-Hee;Yoon, Mi-Hye
    • Korean Journal of Microbiology
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    • v.54 no.1
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    • pp.24-30
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    • 2018
  • Norovirus infection is a leading cause of nonbacterial gastroenteritis outbreaks. New variants of GII.4 have emerged approximately every 2~3 years and have caused norovirus gastroenteritis pandemics globally. In this study, analysis and molecular genetic characteristics of the norovirus gastroenteritis outbreaks 2,917 samples in Gyeonggi-Do from 2014 to 2015. As a result, 247 samples out of 2,917 samples are positive for norovirus. Norovirus molecular genetic characteristics of the GI 8 types (GI-1, 2, 3, 4, 5, 6, 12, 14), GII 10 types (GII - 2, 3, 4, 5, 6, 11, 12, 14, 16, 17). Genome sequences of isolated noroviruses were similar to those of new GII.17 Kawasaki 2014 variants with 96.6 identity, suggesting that these viruses were imported from overseas. 44% of virus incidence was originated from school meal service. Therefore, a continuous monitoring and school sanitation should be required for preventing a massive virus outbreak.

Diversity of Anther-derived Plants in Hot pepper (Capsicum annuum L.) (고추 약배양 후대식물체의 다양성)

  • 권오열;김용권;윤화모
    • Korean Journal of Plant Tissue Culture
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    • v.25 no.3
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    • pp.165-169
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    • 1998
  • Anthers of three cross combinations of hot-pepper(Capsicum annuum L.) were cultured on Dumas De Vaulx medium supplemented with some growth regulators. The embryo production efficiency and the diversity for agronomic traits in $A_2$ lines were investigated. The embryo production frequencies of hybrid combinations were ranged from 16.4% to 43.4%, the highest embryo induction combination was DGSH $\times$ C-NH with 43.4% embryogenic efficiency. Among total 275 $A_2$ lines, phenotypic variants were found in six lines, 2.1% variant frequency. The diversity of $A_2$ lines derived from anther culture was different according to the cross combinations. Fruit color was within parental range, no transgressive variation was observed. However leaf color showed transgressive variation. In fruit length, fruit width and fruit weight, one C-HC $\times$ DGSH and DGSH $\times$ C-NH showed great diversity compared with doner parents while Cheokjo 1 $\times$ C-NH crossed with Cheokjo 1 with big fruit shape showed small diversity. Stem length to 1st branch was relatively similer to or longer than donor parents. Stem thick exhibited remarkable diversity. Node number to 1st branch distributed alomost within the range of donor parents in C-HC $\times$ DGSH combination, however great transgressive variations were observed in DGSH $\times$ C-NH and Cheokjo 1 $\times$ C-NH combinations.

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A Study on Food Intake of a Rural Community Housewives with the Related Factors and Nutrition Education-Index (일부 농촌 지역사회 주부의 식품섭취상태와 그 관련된 요인 및 영양교육지표에 관한 연구 - 경기도 남양주군 수동면 중심으로 -)

  • Kang, Ji-Yong;Wie, Ja-Hyung;Park, Jeong-Sun;Ha, Eun-Hee;Kwak, Jeong-Ok
    • Journal of Preventive Medicine and Public Health
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    • v.22 no.3 s.27
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    • pp.406-422
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    • 1989
  • This study is aimed at developing a nutritional task of a community' as a public health activities of Su-Dong Myun, Demonstration Project area of Ewha Womans University. The content of this study is the points of nutritional diagnosis for the residents nutritional evaluation, the analysis of the related factors and the educational material with Nutrition Education-Index. Two hundreds housewives were examined during the period of Jan. 20 to Jan. 30 in 1989. 1. In terms of the housewives' age, those aged 30 to 39 were 32.5% which was the highest and educational level, graduation of primary school was 31.5% which was the highest. The housewives who had no job were 60.0% and those who participated in community activities were 56.5%. 2. In terms of the points of nutritional diagnosis, 50 to 74 points were 51.5% which was the highest and total average was $65.1{\pm}15.0$. 3. As for the points of nutritional knowledge, the average was 54.9 points, attitude was 77.4 points and eating practice was 70.8points. 4. The number of clinical symptoms of nutritional deficiency was 16.1 ones per person. 5. As for the relation which nutritional knowledge, attitude, eating practice exert on one another, nutritional knowledge has negative correlation with eating practice(-0.04) and attitude has some correlation with eating practice(0.17). 6. The variable having to do with the points of nutritional diagnosis showed the highest correlation coefficient(0.55) as the points of nutritional knowledge. 7 As for the variable having to do with the number of the symptoms of nutritional deficiency, the higher points of knowledge(-0.05) is, the higher the totai averse points of nutritional diagnisis(-0.09) is, negative correlation was appeared. 8. The result in which the variant having to do with the number of clinical symptoms of nutritional deficiency was analyzed by multiple regression analysis showed that the lack of time for preparing meals in non agricultural households made the greatest contribution (9% explained) and the households having vegetable garden made the second greatest contribution(3% explained).

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Test turnaround Time for Complete Blood Cell Count using Delta and Panic Value Checks and the Q-flag Limit

  • Koo, Bon-Kyung;Ryu, Kwang-Hyun;Lim, Dae-Jin;Cho, Young-Kuk;Kim, Hee-Jin
    • Korean Journal of Clinical Laboratory Science
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    • v.44 no.2
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    • pp.66-74
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    • 2012
  • Test turnaround time (TAT) is the lead time from reception to reporting. In the complete blood cell count (CBC), 4 units of the XE-2100 (Sysmex Corp., Japan) processed around 80% of quantity, 1 unit of the LH-780 (Beckman-Coulter Incorp., USA) processed around 10% and 1 unit of ADVIA-2120 (Siemens AG, Munich, Germany) processed around 10%. We analyzed the change in the TAT for the CBC for over 7 years, from January of 2005 to December of 2011. The delta check made alterations of delta to WBC, hemoglobin, hematocrit, platelet and metamyelocyte, however, did not made them to band neutrophil, eosinophil, basophil and monocyte. The panic value check made alterations of panic value to hemoglobin, hematocrit, platelet and monocyte. In the criteria of currently slide review, LH-780 and ADVI-2120 analyzers prepared suspect flags of "Blast, Imm NE2, Immature granulocyte, Imm NE1, Left shift, Variant lymphocyte, Atypical lymphocyte, Platelet clumps and NRBC". The New slide review in the XE-2100 analyzer altered the preparations of a smear slide more than a "Platelet clumps flag(${\geq}200unit$), a single flag excluding the "Platelet clumps flag (${\geq}250unit$) and a multiple flag (${\geq}200unit$)". Also, below the 240 unit, medical technologists prepared manual slides selectively according to their evaluations. The automatic reporting rate was 33.4% without alterations, whereas it was 41.0% without alterations, and was thus improved by 7.6%. The slide review rate was 15.2% before using the Q-flag limit, whereas it was 12.1% for a reduce 3.1%. TAT was 45 minutes without the creation alterations of the delta and panic value checks, whereas it was 35 minutes after making alterations of the delta and panic value checks and thus was shortened by 10 minutes. We came to the conclusion that the establishment and operation of delta and panic value checks and slide review criteria suitable for laboratory environment can reduce unnecessary smear slides, re-checking, re-sampling, re-testing, telephone inquiries and concentrated workloads during specific times of the day.

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Estimation of Forest Biomass based upon Satellite Data and National Forest Inventory Data (위성영상자료 및 국가 산림자원조사 자료를 이용한 산림 바이오매스 추정)

  • Yim, Jong-Su;Han, Won-Sung;Hwang, Joo-Ho;Chung, Sang-Young;Cho, Hyun-Kook;Shin, Man-Yong
    • Korean Journal of Remote Sensing
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    • v.25 no.4
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    • pp.311-320
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    • 2009
  • This study was carried out to estimate forest biomass and to produce forest biomass thematic map for Muju county by combining field data from the 5$^{th}$ National Forest Inventory (2006-2007) and satellite data. For estimating forest biomass, two methods were examined using a Landsat TM-5(taken on April 28th, 2005) and field data: multi-variant regression modeling and t-Nearest Neighbor (k-NN) technique. Estimates of forest biomass by the two methods were compared by a cross-validation technique. The results showed that the two methods provide comparatively accurate estimation with similar RMSE (63.75$\sim$67.26ton/ha) and mean bias ($\pm$1ton/ha). However, it is concluded that the k-NN method for estimating forest biomass is superior in terms of estimation efficiency to the regression model. The total forest biomass of the study site is estimated 8.4 million ton, or 149 ton/ha by the k-NN technique.

Fermentation and Quality Characteristics of Cheongkookjang Prepared with Germinated Soybean (발아콩으로 제조한 청국장의 발효 및 품질특성)

  • Beak, Lag-Min;Kang, Kyoung-Myoung;Park, La-Young;Lee, Shin-Ho
    • Food Science and Preservation
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    • v.19 no.4
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    • pp.547-553
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    • 2012
  • Cheongkookjang that was prepared with three kinds of soybeans [non-germinated soybean (NG), soybeans germinated for 12 hr (GS12), and soybeans germinated for 24 hr (GS24)] were investigated. The changes in the pH, total aerobes, and slime content of Cheongkookjangs that were prepared with NG, GS12 and GS24 did not significantly differ during their fermentation for 48 hr at $40^{\circ}C$. The total aerobes of the Cheongkookjang variants reached $10^8{\sim}10^9$ CFU/mL after theirfermentation for 48 hr. The total polyphenol content and DPPH-radical-scavenging activities the germionated and non-germinated soybeans did not significantly differ, but increased significantly according to the germination degree during the fermentation. The isoflavone content of the Cheongkookjang with the germinated soybean increased. The isoflavone content of Cheongkookjang variant were 0.141 mg/g (NG), 0.369 mg/g (GS12) and 0.569 mg/g (GS24); their free amino acid contents were 254.26 mg% (NG), 337.49 mg% (GS12) and 528.78 mg% (GS24); and their sensory characteristics such as their taste, color, flavor, bitter taste, texture, and overall acceptability did not significantly differ.

Construction of fluorescent red silk using fibroin H-chain expression system (누에 형질전환에 의한 견사선에서의 적색형광단백질 발현)

  • Kim, Sung Wan;Yun, Eun Young;Choi, Kwang-Ho;Kim, Seong Ryul;Park, Seung Won;Kang, Seok Woo;Kwon, O-Yu;Goo, Tae Won
    • Journal of Sericultural and Entomological Science
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    • v.50 no.2
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    • pp.87-92
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    • 2012
  • We constructed the fibroin H-chain expression system to produce Discosoma sp. red fluorescent protein variant2 (DsRed2) in transgenic silkworm cocoon. Fluorescent cocoon could be made by fusing DsRed2 cDNA to the heavy chain gene and injecting it into a silkworm. The DsRed2 fusion protein, each with N- and C-terminal sequences of the fibroin H-chain, was designed to be secreted into the lumen of the posterior silk glands. The expression of the DsRed2/H-chain fusion gene was regulated by the fibroin H-chain promoter. The use of the 3xP3-driven EGFP cDNA as a marker allowed us to rapidly distinguish transgenic silkworms. The EGFP fluorescence became visible in the ocelli and in the central and peripheral nervous system on the seventh day of embryonic development. A mixture of the donor and helper vector was micro-injected into 1,020 Kumokjam, bivoltin silkworm eggs. We obtained 6 broods. The cocoon was displayed strong red fluorescence, proving that the fusion protein was present in the cocoon. Accordingly, we suggest that the DsRed2 fluorescence silk will enable the production of novel biomaterial based on the transgenic silk.

Feline adipose tissue-derived mesenchymal stem cells pretreated with IFN-γ enhance immunomodulatory effects through the PGE2 pathway

  • Park, Seol-Gi;An, Ju-Hyun;Li, Qiang;Chae, Hyung-Kyu;Park, Su-Min;Lee, Jeong-Hwa;Ahn, Jin-Ok;Song, Woo-Jin;Youn, Hwa-Young
    • Journal of Veterinary Science
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    • v.22 no.2
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    • pp.16.1-16.13
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    • 2021
  • Background: Preconditioning with inflammatory stimuli is used to improve the secretion of anti-inflammatory agents in stem cells from variant species such as mouse, human, and dog. However, there are only few studies on feline stem cells. Objectives: This study aimed to evaluate the immune regulatory capacity of feline adipose tissue-derived (fAT) mesenchymal stem cells (MSCs) pretreated with interferon-gamma (IFN-γ). Methods: To assess the interaction of lymphocytes and macrophages with IFN-γ-pretreated fAT-MSCs, mouse splenocytes and RAW 264.7 cells were cultured with the conditioned media from IFN-γ-pretreated MSCs. Results: Pretreatment with IFN-γ increased the gene expression levels of cyclooxygenase-2, indoleamine 2,3-dioxygenase, hepatocyte growth factor, and transforming growth factor-beta 1 in the MSCs. The conditioned media from IFN-γ-pretreated MSCs increased the expression levels of M2 macrophage markers and regulatory T-cell markers compared to those in the conditioned media from naive MSCs. Further, prostaglandin E2 (PGE2) inhibitor NS-398 attenuated the immunoregulatory potential of MSCs, suggesting that the increased PGE2 levels induced by IFN-γ stimulation is a crucial factor in the immune regulatory capacity of MSCs pretreated with IFN-γ. Conclusions: IFN-γ pretreatment improves the immune regulatory profile of fAT-MSCs mainly via the secretion of PGE2, which induces macrophage polarization and increases regulatory T-cell numbers.

Effects Of Collective Art Therapy on The Depression, Communication, Self-Efficacy, and the Subjective Happiness of the Elderly with Dementia (회상요법을 적용한 집단미술치료가 치매노인의 우울, 의사소통, 자기효능감, 주관적 행복감에 미치는 영향)

  • Kim, Gyoung-Hwa
    • Industry Promotion Research
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    • v.6 no.4
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    • pp.59-68
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    • 2021
  • This study has identified the effect of reminiscence-based collective art therapy on the depression, interpersonal relationships, and the subjective sense of happiness among the elderly with dementia. The study was conducted on 30 volunteers with dementia aged 65 or older attending the S Weekly Care Center located in S-gun as subjects during the period between November 7, 2020 and January 2, 2021 with one session week for a total of 12 sessions. The SPSS 24.0 statistics program has been used for various data analyses, including confidence verification, cross tabulation analysis independent sample T-test, 3×2 multi-variant analysis, and the intergroup independent sample T-test between the groups. The study findings are as follows, First, the collective art therapy based on reminiscence therapy is effective in reducing the depression among the elderly with dementia. Second, the collective art therapy based on reminiscence therapy is effective in promoting interpersonal relationships among the elderly with dementia. Third, the collective art therapy based on reminiscence therapy is effective in improving the subjective sense of happiness among the elderly with dementia. These study findings are meaningful in that they have provided an informative basic data on the reminiscence-based collective art therapy.