• Journal of Animal Science and Technology
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• v.48 no.3
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• pp.337-344
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• 2006

The objective of this study was to compare of genetic parameter estimates on carcass traits of Hanwoo(Korean Cattle) according to modeling with Gibbs sampler and MTDFREML. The data set consisted of 1,941 cattle records with 23,058 animals in pedigree files at Hanwoo Improvement Center. The variance and covariance among carcass traits were estimated via Gibbs sampler and MTDFREML algorithms. The carcass traits considered in this study were longissimus dorsi area, backfat thickness, and marbling score. Genetic parameter estimates using Gibbs sampler and MTDFREML from single-trait analysis were similar with those from multiple-trait analysis. The estimated heritabilities using Gibbs sampler were .52～.54, .54 ～.59, and .42～.44 for carcass traits. The estimated heritabilities using MTDFREML were .41, .52～.53, and .31～.32 for carcass traits. The estimated genetic correlation using Gibbs sampler and MTDFREML of LDA between BF and MS were negatively correlated as .34～.36, .23～.37. Otherwise, genetic correlation between BF and MS was positive genetic correlation as .36～.44. The correlations of breeding value for marbling score between via MTDFREML and via Gibbs sampler were 0.989, 0.996 and 0.985 for LDA, BF and MS respectively.

• The Korean Journal of Applied Statistics
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• v.22 no.3
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• pp.617-626
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• 2009

A series of recent papers reported that the inter-gene correlations in Affymetrix microarray data sets were strong and long-ranged, and the assumption of independence or weak dependence among gene expression signals which was often employed without justification was in conflict with actual data. Qui et al. (2005) indicated that applying the nonparametric empirical Bayes method in which test statistics were pooled across genes for performing the statistical inference resulted in the large variance of the number of differentially expressed genes. Qui et al. (2005) attributed this effect to strong and long-ranged inter-gene correlations. Klebanov and Yakovlev (2007) demonstrated that the inter-gene correlations provided a rich source of information rather than being a nuisance in the statistical analysis and they developed, by transforming the original gene expression sequence, a sequence of independent random variables which they referred to as a ${\delta}$-sequence. We note in this report using two cDNA microarray data sets experimented in this country that the strong and long-ranged inter-gene correlations were still valid in cDNA microarray data and also the ${\delta}$-sequence of independence could be derived from the cDNA microarray data. This note suggests that the inter-gene correlations be considered in the future analysis of the cDNA microarray data sets.

• Korean Parent-Child Health Journal
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• v.8 no.1
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• pp.75-88
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• 2005

Purpose: This study was to examine the relationship between perceived the past parent-child relationship(caring and overprotection), present parent-child attachment (communication, confidence, alienation) and self-concept of woman college students. Method: The data was collected from March 15 through 26, 2004. The subjects in this study were 395 students who attended universities located in N and T city. The data analyzed using with SAS program, and analysis of variance, Pearson correlation analysis, multiple regression. Results: Concerning the connection of demographic variables to the past parent-child relations(caring and overprotection), current parent-child attachment(communication, confidence, alienation) made a Significant difference in economic family standard (p<.05), educational level of their fathers(p<.01), birth of order(p<.05) and whether or not they lived with their parents under the same roof(p<.05), past experience of living with their parents under the same roof(p<.01). The relationship of the past parent-child relations(caring and overprotection), and current parent-child attachment(communication, confidence, alienation) made a significant difference to communication(p<.001), confidence(p<.001), alienation(P<.001). The correlation among the past parent-child relations(caring and overprotection), current parent-child attachment(communication, confidence, alienation) and self-concept, caring had significantly positive correlation(p<.001) with communication(r=0.631), confidence(r=0.669) and self-concept(r=0.520), and had significantly negative correlation(p<.001) with overprotection(r=-0.369), alienation(r=-0.531). The overprotection had Significantly negative correlation(p<.001) with communication(r=-0.303) confidence(r=-0.369) and self-concept(r=-0.292), and that had significantly positive correlation(p<.001) with alienation (r=0.275). Overall, the past parent child relations(caring and overprotection) made a 28.2% prediction of self-concept, and the current parent-child attachment(communication, confidence and a sense or alienation) made a 46.1% prediction or self-concept, and their predictability was all significant. Conclusion: This study suggests that perceived the past parent-child relationship(caring and overprotection) is significant influencing factors on present parent-child attachment(communication, confidence, alienation), self-concept. Therefore, nursing strategy is needed to manage these revealed factors.

• Journal of Korea Water Resources Association
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• v.32 no.4
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• pp.403-415
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• 1999

This study is to derive the rainfall intensity formula based on the representative probability distribution in Korea. The 11 probability distributions which has been widely used in hydrologic frequency analysis are applied to the annual maximum rainfall. The parameters of each probability distribution are estimated by method of moments, maximum likelihood method and method of probability weighted moments. Four tests such as $x^2$-test, Kolmogorv-Smirnov test, difference test and modified difference test are used to determine the goodness of fit of the distributions. The homogeneous tests (Mann-Whitney U test, Kruskal-Wallis one-way analysis of variance of nonparametric test) are applied to find the stations with rainfall homogeneity. The results of homogeneous tests show that there is no representative appropriate distribution for the whole duration in Korea. The whole region could be divided into five zones for 12-durations. The representative probability distribution of each divided zone for 12-durations was determined. The GEV distribution for I,II,V zones and the 3-parameter Weibull distribution for III,IV zones were determined as the representative probability distribution. The rainfall were obtained from representative probability distribution for the selected return periods. Rainfall intensity formula was determined by linearization technique for the rainfall.

• Journal of Life Science
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• v.31 no.10
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• pp.922-928
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• 2021

To profile the microbial compositions of Korean traditional fermented paste made from whole soybeans, Doenjang and Cheonggukjang, and compare their taxonomic differences, we analyzed the V3-V4 region of 16S rRNA of naturally fermented foods by using next generation sequencing. α-Diversity results showed that values indicating bacterial community abundances (OTUs) and richness (ACE, Chao1) were statistically significant (p=0.0001) in Doenjang and Cheonggukjang. Firmicutes was the most common phylum in both groups, representing 97.02% and 99.67% in the Doenjang and Cheonggukjang groups, respectively. Bacillus was the most dominant genus, accounting for 71.70% and 59.87% in both groups. Linear discriminant (LDA) effect size (LEfSe) analysis was performed to reveal the significant ranking of abundant taxa in different fermented foods. A size-effect threshold of 2.0 on the logarithmic LDA score was used for discriminative functional biomarkers. On the species level, Bacillus subtilis, Tetragenococcus halophilus, and Clostridium arbusti were significantly more abundant in Doenjang than in Cheonggukjang, whereas Bacillus thermoamylovorans, Enterococcus faecium, and Lactobacillus sakei were significantly more abundant in Cheonggukjang than in Doenjang. Permutational multivariate analysis of variance (PERMANOVA) showed that the statistical difference in microbial clusters between the two groups was significant at the confidence level of p=0.001. This research could be used as basic research to identify the correlation between the biochemical characteristics of Korean fermented foods and the distribution of microbial communities.

• Journal of Digital Convergence
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• v.17 no.3
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• pp.291-304
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• 2019

The purpose of this study was to identify factors influencing family caregivers' reaction of persons with cancer. The study participants were 130 cancer patients and their family caregivers. Data on participant characteristics, caregiver reaction, perceived social support, and cancer related health literacy were collected from July 17 to November 7, 2018 using a structured questionnaire. Data were analyzed with the SPSS/WIN 23.0 program for descriptive statistics, using independent t-test, one-way analysis of variance, Pearson's correlation coefficient and enter multiple regression analysis. The determining factors affecting caregivers' reaction were in case of spouse of patient(${\beta}=.252$, p=.002), subjective health status(${\beta}=-.207$ p=.012), and health literacy (self-care, patient's needs and preference) (${\beta}=-.411$, p<.001; ${\beta}=.247$, p=.037 respectively), and their explanation power was about 37.9%. This finding underscores the need for developing and application of the individualized education program with health literacy improvement strategies for family caregivers of cancer patients.

• Journal of The Korean Association For Science Education
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• v.38 no.6
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• pp.781-792
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• 2018

In modern society, as technology develops and industry diversifies, students can choose from a variety of career paths. Since science, technology, engineering, and mathematics require a longer education and experience than other fields, it is important to design science education policies based on the competencies required for science, technology, engineering, and mathematics (STEM) occupations. This study explores the definition of science and technology manpower and STEM occupations and identifies core competencies of STEM occupations using standard job information operated and maintained by the US Department of Labor ($O^*NET$). We specially analyzed ratings of the importance of skills (35 ratings), knowledge (33 ratings), and work activities (41 ratings) conducting descriptive analysis and principal component analysis (PCA). As a result, core competencies of STEM occupations consist of STEM problem-solving competency, Management competency, Technical competency, Social service competency, Teaching competency, Design competency, Bio-chemistry competency, and Public service competency, which accounts for 70% of the total variance. This study can be a reference for setting the curriculum and educational goals in secondary and college education by showing the diversity of science and technology occupations and the competencies required for STEM occupations.

• Korean Journal of Food Science and Technology
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• v.54 no.3
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• pp.362-368
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• 2022

The sensory characteristics of nine rice-based distilled soju were determined using check-all-that-apply (CATA) profiling. A total of 53 consumers evaluated the soju for two appearance attributes, nine aroma attributes, nine flavor/taste attributes, four mouth-feel related sensory attributes, and overall desirability. The total sum of CATA terms indicated that 14 characteristics showed frequency differences of over 10 and that there were significant differences among nine samples for eleven sensory attributes as determined using Cochran's q test (p<0.05). Based on correspondence analysis of CATA data, the samples were primarily separated by the first dimension, which accounted for 89% of the total variance among samples. The "brown color," "fruit taste," and "grain aroma" characteristics had higher frequencies than those for the "white color," "acetone aroma," and 'alcohol taste" characteristics. Overall, there was a higher preference for oak-aged samples than for samples aged in other containers. "sweet aroma', 'fruit aroma," and "sweet taste" seemed to positively affect consumer preferences, while "bitter taste," "alcohol taste," and "acetone aroma" appeared to negatively affect consumer preferences as determined by principal coordinate analysis.

• The Journal of the Convergence on Culture Technology
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• v.9 no.6
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• pp.595-604
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• 2023

This study attempted to provide basic data for developing strategies to improve the psychosocial well-being on nursing university students by identifying the mediating effect of resilience on the relationship between clinic practice stress and psychosocial well-being of nursing university students. The subjects of the study were 175 nursing students in their 3^rd and 4^th year who had clinic practice experience at two universities in J province and G city. The SPSS/23.0 program was used to analyze the data with descriptive statistics; an independent t-test, analysis of variance ANOVA, Pearson's correlation coefficient, and mediating effect analysis were performed using Process Macro 4.0. The psychosocial well-being of nursing university students showed a positive correlation with clinical practice stress (r=.472, p<.001), and a negative correlation with resilience (r=-.860, p<.001). Resilience showed a mediating effect on the relationship between clinical practice stress and psychosocial well-being. Based on the results of this study, it is necessary to development and apply systematic programs to reduce clinical practice stress and increase resilience for improving the psychosocial well-being of nursing university students.

• Korean Journal of Clinical Pharmacy
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• v.22 no.1
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• pp.9-12
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• 2012

Background: Cefcapene pivoxil hydrochloride, is an ester-type oral cephem antibiotic. This study was performed to compare the pharmacokinetics and evaluate the bioequivalence of two cefcapene pivoxil hydrochloride 75 mg formulations. Method: In a randomized $2{\times}2$ crossover study, sixty healthy male volunteers were randomly assigned into two groups. After a single dose of 75 mg cefcapene pivoxil hydrochloride oral administration, blood samples were collected at specific time intervals from 0-12 hours. The plasma concentrations of cefcapene pivoxil hydrochloride were determined by LC-MS/MS. The pharmacokinetic parameters were determined from the plasma concentration-time profiles of both formulations. The pharmacokinetic parameters such as $AUC_{last}$, $AUC_{inf}$ and $C_{max}$, were calculated and the 90% confidence intervals for test/reference ratio for pharmacokinetic parameters were obtained by analysis of variance on logarithmically transformed data. Results: The mean value for $AUC_{last}$ in test and reference drug was $4053.1{\pm}876.5\;ng{\cdot}hr/mL$ and $3595.7{\pm}1029.1\;ng{\cdot}h/mL$, respectively. The mean value for $C_{max}$ in test and reference drug was $1324.9{\pm}321.4$ ng/mL and $1159.1{\pm}335.9$ ng/mL, respectively. The 90% confidence intervals of the $AUC_{last}$ and $C_{max}$ ratio for test drug and reference drug were log 1.09-log1.22 and log 1.09-log1.24, respectively. No adverse events were reported by subjects or found on analysis of vital signs or laboratory tests. Conclusion: This single dose study found that the test and reference products met the regulatory criteria for bioequivalence in these health volunteers. Both formulations were safe and well tolerated in 75 mg of cefcapene pivoxil hydrochloride.