• 제목/요약/키워드: Value-point effects

검색결과 491건 처리시간 0.027초

소수성화학물질의 생물축적과 기저독성: 분자크기, 반응속도, 화학적 활성도에 따른 제약 (Bioaccumulation and Baseline Toxicity of Hydrophobic Chemicals: Molecular Size Cutoff, Kinetic Limitations, and Chemical Activity Cut-off)

  • 권정환
    • Environmental Analysis Health and Toxicology
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    • 제23권2호
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    • pp.67-77
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    • 2008
  • It has been observed that the linear relationship between the logarithm of bioconcentration factor (log BCF) of highly hydrophobic chemicals and their log $K_{ow}$ breaks when log $K_{ow}$ becomes greater than 6.0. Consequently, super hydrophobic chemicals were not thought to cause baseline toxicity as a single compound. Researchers often call this phenomenon as "hydrophobicity cutoff" meaning that bioconcentration or corresponding baseline toxicity has a certain cutoff at high log $K_{ow}$ value of hydrophobic organic pollutants. The underlying assumption is that the increased molecular size with increasing hydrophobicity prohibits highly hydrophobic compounds from crossing biological membranes. However, there are debates among scientists about mechanisms and at which log $K_{ow}$ this phenomenon occurs. This paper reviews three hypotheses to explain observed "cutoff": steric effects, kinetic or physiological limitations, and chemical activity cutoff. Although the critical molecular size that makes biological membranes not permeable to hydrophobic organic chemicals is uncertain, size effects in combination with kinetic limitation would explain observed non-linearity between log BCF and log $K_{ow}$. Chemical activity of hydrophobic chemicals generally decreases with increasing melting point at their aqueous solubility. Thus, there may be a chemical activity cutoff of baseline toxicity if there is a critical chemical activity over which baseline effects can be observed.

물방울 무늬의 크기와 배색 변화가 원피스 드레스 이미지에 미치는 영향 - 명도 대비 배색을 중심으로 - (The Effect of Dot Pattern Size and the Variation of Coloration on Dress Wearers' Image Formation - Focused on Coloration of Value Contrast -)

  • 김선미;정수진
    • 복식문화연구
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    • 제16권5호
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    • pp.863-877
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    • 2008
  • The purpose of this study is to investigate the effect of dot pattern size(0.8, 1.8, 2.5, 5, 8), color combination (BG/R, Y/B), value tone(lt/dk, p/g), area-ratio on image information. Sets of stimulus and response scales(7 point semantic) were used as experimental materials. The stimuli were 20 color pictures manipulated with the combination of dot pattern size, color combination, value tone and area-ratio using computer simulation. The subjects were 240 female undergraduates living in Gyeongsangnam-do. Image factor of the stimulus was composed of 4 different components, visibility, chastity.feminity, cuteness and attractiveness. In the visibility, color combination, value tone, area-ratio, dot pattern size showed independent effect. In the chastity feminity, color combination, value tone, showed independent effect. In the cuteness, value tone, area-ratio, dot pattern size showed independent effect. Significant interaction effects of color and area-ratio combination on visibility and cuteness were found. Interaction efforts of color and value tone combination, value tone and area-ratio was significant on cuteness. For visibility image, BG/R combination of color and yellow background/blue dots were effective. For cuteness image, pale/grayish tone and background/dots area-ratio were effective.

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The optimum conversion efficiency in nile blue arabinose system by photogalvanic cell

  • Lal, Mohan;Gangotri, K.M.
    • Advances in Energy Research
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    • 제3권3호
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    • pp.143-155
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    • 2015
  • The Nile blue has been used as a photosensitizer with Arabinose as a reductant in photogalvanic cell for optimum conversion efficiency and storage capacity. Reduction cost of the photogalvanic cell for commercial utility. The generated photopotential and photocurrent are 816.0 mV and $330.0{\mu}A$ respectively. The maximum power of the cell is $269.30{\mu}W$ where as the observed power at power point is $91.28{\mu}W$. The observed conversion efficiency is 0.6095% and the fill factor 0.2566 has been experimentally found out at the power point of the photogalvanic cell, whereas the absolute value is 1.00. The photogalvanic cell so developed can work for 120.0 minutes in dark if it is irradiated for 200.0 minutes that is the storage capacity of photogalvanic cell is 60.00%. The effects of different parameters on the electrical output of the photogalvanic cell have been observed. A mechanism has also been proposed for the photogeneration of electrical energy.

SAVITZKY-GOLAY DERIVATIVES : A SYSTEMATIC APPROACH TO REMOVING VARIABILITY BEFORE APPLYING CHEMOMETRICS

  • Hopkins, David W.
    • 한국근적외분광분석학회:학술대회논문집
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    • 한국근적외분광분석학회 2001년도 NIR-2001
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    • pp.1041-1041
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    • 2001
  • Removal of variability in spectra data before the application of chemometric modeling will generally result in simpler (and presumably more robust) models. Particularly for sparsely sampled data, such as typically encountered in diode array instruments, the use of Savitzky-Golay (S-G) derivatives offers an effective method to remove effects of shifting baselines and sloping or curving apparent baselines often observed with scattering samples. The application of these convolution functions is equivalent to fitting a selected polynomial to a number of points in the spectrum, usually 5 to 25 points. The value of the polynomial evaluated at its mid-point, or its derivative, is taken as the (smoothed) spectrum or its derivative at the mid-point of the wavelength window. The process is continued for successive windows along the spectrum. The original paper, published in 1964 [1] presented these convolution functions as integers to be used as multipliers for the spectral values at equal intervals in the window, with a normalization integer to divide the sum of the products, to determine the result for each point. Steinier et al. [2] published corrections to errors in the original presentation [1], and a vector formulation for obtaining the coefficients. The actual selection of the degree of polynomial and number of points in the window determines whether closely situated bands and shoulders are resolved in the derivatives. Furthermore, the actual noise reduction in the derivatives may be estimated from the square root of the sums of the coefficients, divided by the NORM value. A simple technique to evaluate the actual convolution factors employed in the calculation by the software will be presented. It has been found that some software packages do not properly account for the sampling interval of the spectral data (Equation Ⅶ in [1]). While this is not a problem in the construction and implementation of chemometric models, it may be noticed in comparing models at differing spectral resolutions. Also, the effects on parameters of PLS models of choosing various polynomials and numbers of points in the window will be presented.

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2015년부터 2017년까지 시행한 이압요법을 통한 남자 고등학생 금연효과 관찰 (Observation of the Effects of Auricular Acupressure on Smoking Cessation in Male High School Students from 2015 to 2017)

  • 이기향;전상우;강세영
    • 대한한방내과학회지
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    • 제40권6호
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    • pp.1202-1209
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    • 2019
  • Objectives: The purpose of this study was to confirm the effects of an auricular acupressure (AA) program for smoking cessation in high school students from 2015 to 2017. Methods: The study investigated 12 high school students who had been smokers. Subjects were treated for three years. Each program was composed of five AA treatments. Average daily smoking and adverse reactions were checked for one week before each procedure. The AA was administered weekly at the endocrine point, lung point, throat point, nasal fossae point, bronchial tube point, and mouth point. Results: The mean number of cigarettes smoked per day after each year of treatment significantly decreased from 5.33±3.58 to 3.54±2.08 in 2015 (p=0.046). However, it increased from 5.75±2.30 to 6.00±3.61 in 2017 (p=0.80). The number of cigarettes smoked before treatment was found to be higher than the number of cigarettes after treatment in the previous year. No significant results were obtained from analysis of the change in the amount of smoking within each year. Conclusion: Social influence, such as the subject's academic stress and peer relationships, may have been a major factor in the change in the amount of smoking. Although the AA did not show a strong effect in smoking cessation, it appears to have value as a supplementary means of stopping smoking.

Modeling the Relationship between Expected Gain and Expected Value

  • Won, Eugene J.S.
    • Asia Marketing Journal
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    • 제18권3호
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    • pp.47-63
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    • 2016
  • Rational choice theory holds that the alternative with largest expected utility in the choice set should always be chosen. However, it is often observed that an alternative with the largest expected utility is not always chosen while the choice task itself being avoided. Such a choice phenomenon cannot be explained by the traditional expected utility maximization principle. The current study posits shows that such a phenomenon can be attributed to the gap between the expected perceived gain (or loss) and the expected perceived value. This study mathematically analyses the relationship between the expectation of an alternative's gains or losses over the reference point and its expected value, when the perceived gains or losses follow continuous probability distributions. The proposed expected value (EV) function can explain the effects of loss aversion and uncertainty on the evaluation of an alternative based on the prospect theory value function. The proposed function reveals why the expected gain of an alternative should exceed some positive threshold in order for the alternative to be chosen. The model also explains why none of the two equally or similarly attractive options is chosen when they are presented together, but either of them is chosen when presented alone. The EV function and EG-EV curve can extract and visualize the core tenets of the prospect theory more clearly than the value function itself.

전기저항 측정기법을 이용한 오염물질 누출감지시스템의 개발: II. 현장모형시험을 통한 매립지에의 적용성 평가 (Development of Contaminant Leakage Detection System Using Electrical Resistance Measurement: ll. Evaluation of Applicability for Landfill Site by Field Model Tests)

  • 오명학;이주형;박준범;김형석;강우식
    • 한국지반공학회논문집
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    • 제17권6호
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    • pp.225-233
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    • 2001
  • 본 논문에서는 격자망식 전선배치에 의한 침출수 누출감지시스템을 개발하기 위하여 현장모형시험을 통하여 적용성을 평가하였으며, 전기회로시험을 통하여 격자망 전선 배치에서 발생하는 전기회로적 효과를 파악하고자 하였다. 침출수는 전기저항을 감소시키기 때문에 누출지점에서는 다른 지점에 비해 낮은 전기저항값을 나타내었다. 따라서, 전기저항을 측정하는 본 누출감지시스템에 의하여 임의 지점에서 발생하는 침출수의 누출 감지가 가능하였으며, 평면적 분포도를 통하여 누출위치의 파악이 가능하였다. 전기저항이 감소된 지점과 동일한 전선상에 위치한 다른 센서에 서의 측정값도 약간 감소하는 경향을 나타내었으나, 이는 저항이 작은 곳으로 전류의 흐름이 발생하는 전기회로적 효과로 설명할 수 있었다.

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형질전환 비만모델 수컷 hGHTg rats에서 경신해지환(輕身解脂丸)(GGT1)이 체중 및 사료섭취량에 미치는 영향 (The effects GyeongshinhaeGihwan 1 (GGT1) has on the hGHTg (human growth hormone transgenic) obese male rats' body weight and their amount of feed intake)

  • 정양삼;최승배;김훈;신순식
    • 대한본초학회지
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    • 제21권1호
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    • pp.1-7
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    • 2006
  • Objectives: To find out the effects GGT1, an antiobestic drug widely used clinics, has on the amount of feed intake, the amount of change in the body weight and the food efficiency ratio using the data from the hGHTg obese male rats. Also, to evaluate in terms of antiobestic effects, the difference between GGT1 and reductil (sibutramine), which has been approved by the FDA of the United States. Methods: We measured the change in body weight and the amount of feed intake for 8 weeks by categorizing the hGHTg obese male rats into three groups: the control group, the GGT1 group, and the reductil (RD) group. We also evaluated the antiobestic effect by calculating the food efficiency ratio, which is the increase of bodyweight divided by the amount of feed intake. Results: In case of body weight, moderate slope of the curve in the graph of GGT1 group could mean that the weight is decreasing as time flows. In case of food efficiency ratio, the p-value was 0.745 in a test for determining if an interaction exists between the group and the point of measurement, meaning that it does not exist; also, the p-value in a test for the effect of level of repetition in food efficiency ratio according to the point of measurement equaled 0.002. Conclusion: The drug-treated groups had a greater inhibitory effect in feed intake than the control group. The results showed the food efficiency ratio had a tendency to decrease. The GGT1 group in particular was under a greater effect than the RD group.

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치매환자의 증상정도가 주부양자의 우울에 미치는 영향 : 가족지지의 보호효과를 중심으로 (The effects of symptoms of dementia elderly on the primary caregiver's depression : moderating effects of family support)

  • 박선원;곽주연
    • 한국가족관계학회지
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    • 제21권3호
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    • pp.3-23
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    • 2016
  • Objectives: The purpose of this study is to examine the effects of symptoms of dementia elderly on the primary caregiver's depression. In addition, moderating effect of family support was examined. Based on the results, the necessity for intervention in the level of social welfare as a way to mitigate primary caregiver's depression was suggested. Method: In order to accomplish these purposes, a total of 197 who are spouse and adult-children of dementia elderly using day care facilities or services in Seoul, Gyeonggi, Busan province, South Korea were utilized. Data were analyzed by frequency analysis and descriptive statistics, regression model analysis with SPSS 18.0. Results: In case of analysis results, the mean value was reported 0.9 out of four point about primary caregiver's depression and the mean value of family support was reported 3.34 out of five point. And besides, the analysis result of dementia elderly's symptoms showed that prevalence of depression/dysphoria were 62.2%, prevalence of aberrant motor were 61.3%, prevalence of apathy/indifference were 56.6%. Crucial findings are as follows: the symptoms of dementia elderly was significantly associated with the primary caregiver's depression. At the same time, family support significantly influenced lower level of the primary caregiver's depression. While, in the relationship between the symptoms of dementia elderly and the primary caregiver's depression, family support has a moderation effect by important protection factor. Conclusions: From these findings, the necessities to provide the care service for dementia elderly to help improve symptoms of dementia as well as the policy and service to manage the mental health of the family as primary caregiver were suggested. Also, the necessities to provide the family therapy program to improve the relationship with family members were suggested.

쌀당화액을 활용한 호상요구르트 제조의 최적화 (Optimization of Curd Yogurt Production Using Saccharified Rice Solution by Response Surface Methodology)

  • 김옥선;성정민
    • 한국식품조리과학회지
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    • 제31권4호
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    • pp.485-496
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    • 2015
  • This study was carried out to establish the optimal conditions for curd yogurt using saccharified rice solution. A central composite design was applied to investigate the effects of pectin (2.8~8.4 g), skim milk (14~70 g) and oligosaccharide (28~84 g) ratio on the physicochemical and sensory characteristics of curd yogurt using saccharified rice solution. pH, total acidity, and color value, were analyzed and sensory evaluation was performed. The pH of curd yogurt decreased with decreasing pectin and oligosaccharide ratio. The addition of pectin had a significant effect on the viscosity while skim milk had a significant effect on the color value (a and b value). The results of sensory evaluation showed that, oligosaccharide and skim milk had significant effects on sweetness and sour taste. Oligosaccharide and skim milk masked the sour taste of curd yogurt. The optimum range of ingredients for curd yogurt using saccharified rice solution was predicted to be 4.27~4.90 g of pectin, 30.80~41.30 g of skim milk, and 28.00~36.10 g of oligosaccharide. Based on the overlapped results of physicochemical and sensory evaluation, the optimal amounts of pectin, skim milk and oligosaccharide were 4.59 g, 36.50 g and 32.05 g, respectively.