• The Journal of Korean Medical History
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• v.24 no.2
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• pp.25-55
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• 2011

The currently existing "Bonchojeonghwa (本草精華)" is a manuscript without the preface and the epilogue, composed of 2 books in 2 volumes. This book is a quintessence of knowledge on science of medicinal ingredients (medicinal phytology I herbal science) as well as an trial of new development in Chosun medical science. I.e. this book includes surprising change representing medical science in Chosun dynasty as a single publication on science of medicinal ingredients. It holds a value essential to clinician as a specialized book in medicinal ingredients, and Includes richer content on medicinal ingredients than any other books published before. In addition, it is away from boring list-up of superfluous knowledge as seen in "Bonchokangmok(本草綱目)" published in China, and well summarizes essential knowledge which can be used within a range of medicines available in Korea. This book has an outstanding structure that can be even used in today's textbook on science of medicinal ingredients, as it has clear theory, system and classification. Because it handles essential learning points prior to prescription to disease, it is possible to configure new prescription and adjustment of medicinal materials. Moreover, this book can play a good role for linguistic study at the time of publication, because it describes many drugs in Hangul in many parts of the book. "Bonchojeonghwa" includes a variety of animals, plants and mineral resources in Korea, like "Bonchokangmok" which was recently listed in UNESCO. As such, it has a significance in natural history as well as pharmacy in Korean Medicine. It has various academic relationships all in biologic & abiologic aspects. It has importance in sharing future biological resources, building up international potential, setting up the standard for biologic species under IMF system, and becoming a base for resource diplomacy. We should not only see it as a book on medicinal ingredients in terms of Oriental Medicine, but also make an prudent approach to it in terms of study strengthening Korea's national competitiveness. After bibliographical reviewing on the features & characteristics of the only existing copy of "Bonchojeonghwa" housed in Kyujanggak(奎章閣) of Seoul National University, the followings are noted. First, "Bonchojeonghwa" is a specialized book on medicinal ingredients voluntarily made by private hands to distribute knowledge on drugs in the desolate situation after Imjinoeran (Japanese Invasion in 1592), without waiting for governmental help. Second, it raised accessibility and practicality by new editing. Third, it classified 990 different kinds of drugs into plant, animal, and mineral at large, and dassified more in detail into 15 'Bu' and 48 'Ryu' at 258 pages. Fourth, the publication of this book is estimated to be around 1625~1633, at the time of Injo's reign in 17th century. Fifth, it contains the existing & up-to-date knowledge at the time of publication, and it is possible to see the supply-demand situation by Hangul descriptions in 149 places in the book. By the fact that there are many linguistic evidences of 17th century, explains well when the book was published.

• Journal of the korean academy of Pediatric Dentistry
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• v.28 no.4
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• pp.661-667
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• 2001

Though a consensus seems to exist about the regulation of the use of sugar-containing food, however. an unrecognized and significant supply of cariogenic carbohydrate remains in the form of sugar-containing liquid oral medicine to prevent dental caries. children who are taking long-term sugar-containing liquid medicine have an increased risk of developing dental caries. The aim of this study is to get the information about the sugars in liquid medicines prescribed for the children. To get the information, the number and date of all prescriptions of liquid medicines for one month at pediatric hospital of Seoul National University Hospital were investigated. From that data, the most frequently used pediatric oral liquid medicine is presented. Then, for the information of the type and contents of sweeteners in that preferred medicines, the manufacturers of each medicines were asked for the data of sugar types and contents, and the informations about the medicine contents were collected via facsimile. The most frequently used pediatric oral liquid medicine were followed as expectorant, purge, antibiotic, drug for iron deficiency anemia, sedative, antihistamine, anticonvulsant, NSAIDs in order. The mean value of sweetener content in liquid medicines was $52.3{\pm}22.4g/100ml$ and most frequently used sweetener is sucrose.

• Journal of Radiation Protection and Research
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• v.45 no.2
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• pp.76-80
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• 2020

Background: To improve the measurement accuracy of liquid-scintillation counting for activity standardization, it is necessary to significantly reduce the background caused by thermal noise or after-pulses. We have therefore improved a movable 3 photomultiplier (3PM)-γ coincidence-counting method using the logical sum of three double coincidences for β events. Materials and Methods: We designed a new data-acquisition system in which β events are obtained by counting the logical sum of three double coincidences. The change in β-detection efficiency can be derived by moving three photomultiplier tubes sequentially from the liquid-scintillation vial. The validity of the method was investigated by activity measurement of ¹³⁴Cs calibrated at the Korea Research Institute of Standards and Science (KRISS) with 4π(PC)β-γ(NaI(Tl)) coincidence counting using a proportional counter (PC) for the β detector. Results and Discussion: Measurements were taken over 14 counting intervals for each liquidscintillation sample by displacing three photomultiplier tubes up to 45 mm from the sample. The dead time in each β- and γ-counting channel was adjusted to be a non-extending type of 20 ㎲. The background ranged about 1.2-3.3 s^-1, such that the contributions of thermal noise or after-pulses were negligible. As the β-detection unit was moved away from the sample, the β-detection efficiencies varied between 0.54 and 0.81. The result obtained by the method at the reference date was 396.3 ± 1.7 kBq/g. This is consistent with the KRISS-certified value of 396.0 ± 2.0 kBq/g within the uncertainty range. Conclusion: The movable 3PM-γ method developed in the present work not only succeeded in reducing background counts to negligible levels but enabled β-detection efficiency to be varied by a geometrical method to apply the efficiency extrapolation method. Compared with our earlier work shown in the study of Hwang et al. [2], the measurement accuracy has much improved. Consequently, the method developed in this study is an improved method suitable for activity standardization of β-γ emitters.

• Korean Journal of Agricultural and Forest Meteorology
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• v.21 no.2
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• pp.75-84
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• 2019

In this study, the random forest approach was used to predict the national mean rice yield of South Korea by using mean climatic factors at a national scale. A random forest model that used monthly climate variable and year as an important predictor in predicting crop yield. Annual yield change would be affected by technical improvement for crop management as well as climate. Year as prediction factor represent technical improvement. Thus, it is likely that the variables of importance identified for the random forest model could result in a large error in prediction of rice yield in practice. It was also found that elimination of the trend of yield data resulted in reasonable accuracy in prediction of yield using the random forest model. For example, yield prediction using the training set (data obtained from 1991 to 2005) had a relatively high degree of agreement statistics. Although the degree of agreement statistics for yield prediction for the test set (2006-2015) was not as good as those for the training set, the value of relative root mean square error (RRMSE) was less than 5%. In the variable importance plot, significant difference was noted in the importance of climate factors between the training and test sets. This difference could be attributed to the shifting of the transplanting date, which might have affected the growing season. This suggested that acceptable yield prediction could be achieved using random forest, when the data set included consistent planting or transplanting dates in the predicted area.

• Journal of Distribution Science
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• v.13 no.9
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• pp.103-112
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• 2015

Purpose - This paper aims to provide a step-by-step approach to factor analytic procedures, such as principal component analysis (PCA) and exploratory factor analysis (EFA), and to offer a guideline for factor analysis. Authors have argued that the results of PCA and EFA are substantially similar. Additionally, they assert that PCA is a more appropriate technique for factor analysis because PCA produces easily interpreted results that are likely to be the basis of better decisions. For these reasons, many researchers have used PCA as a technique instead of EFA. However, these techniques are clearly different. PCA should be used for data reduction. On the other hand, EFA has been tailored to identify any underlying factor structure, a set of measured variables that cause the manifest variables to covary. Thus, it is needed for a guideline and for procedures to use in factor analysis. To date, however, these two techniques have been indiscriminately misused. Research design, data, and methodology - This research conducted a literature review. For this, we summarized the meaningful and consistent arguments and drew up guidelines and suggested procedures for rigorous EFA. Results - PCA can be used instead of common factor analysis when all measured variables have high communality. However, common factor analysis is recommended for EFA. First, researchers should evaluate the sample size and check for sampling adequacy before conducting factor analysis. If these conditions are not satisfied, then the next steps cannot be followed. Sample size must be at least 100 with communality above 0.5 and a minimum subject to item ratio of at least 5:1, with a minimum of five items in EFA. Next, Bartlett's sphericity test and the Kaiser-Mayer-Olkin (KMO) measure should be assessed for sampling adequacy. The chi-square value for Bartlett's test should be significant. In addition, a KMO of more than 0.8 is recommended. The next step is to conduct a factor analysis. The analysis is composed of three stages. The first stage determines a rotation technique. Generally, ML or PAF will suggest to researchers the best results. Selection of one of the two techniques heavily hinges on data normality. ML requires normally distributed data; on the other hand, PAF does not. The second step is associated with determining the number of factors to retain in the EFA. The best way to determine the number of factors to retain is to apply three methods including eigenvalues greater than 1.0, the scree plot test, and the variance extracted. The last step is to select one of two rotation methods: orthogonal or oblique. If the research suggests some variables that are correlated to each other, then the oblique method should be selected for factor rotation because the method assumes all factors are correlated in the research. If not, the orthogonal method is possible for factor rotation. Conclusions - Recommendations are offered for the best factor analytic practice for empirical research.

• Journal of Korean Home Economics Education Association
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• v.17 no.1 s.35
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• pp.15-27
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• 2005

This study is purposed to investigate the high school students' family strengths by interests and usefulness of technology$\cdot$home economics. The subject of this study were 533 high school students in Kyungsangnamdo region, three high schools were selected in urban Jinju and three other schools were selected in countryside of Hapchun. The collected data was processed by SAS program, a social. scientific and statistical processing program, and analyzed the date using the statistical methods of frequency, t-test, one-way ANOVA, Duncan Multiple Range Test and Regression Analysis. The results and conclusions of this study are summarized as follow: 1. The degree of family strengths among high school students was 3.23, when the maximal family strengths value was set to 5.0. The significant variables to the family strengths of high school students were type of school. domestic financial status, average score of term, self-respect. 2. The higher a student recognized of the interests of technology$\cdot$home economics, the healthier their family strengths was. 3. The higher a student recognized of the usefulness of technology . home economics. the healthier their family strengths was. 4. The influential variables to the family strengths in high school students were their self-respect, recognition of the usefulness of technology . home economics, grades, domestic financial status, recognition of the interests of technology$\cdot$home economics.

• International Journal of Highway Engineering
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• v.10 no.4
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• pp.151-159
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• 2008

Performances of retroreflectivity vary place to place, according to traffic volumes and time lengths after striping, depending on pavement marking materials and colors. The present paper uses the nation wide data of retroreflectivity, which has been collected from freeways and then tries to develop the regression curve setting traffic volume and service life as independent variables and retroreflectivities as dependent variables. The DB system includes two year's measurement in $2005{\sim}2006$ over Korean freeway pavement marking at an interval of three months for the period. The mobile measurement system, a laserlux, was employed for the purpose. The DB has provided a lot of information about materials and performance of the specific pavement marking such as geometric features, traffic volumes, material characteristics and the installation date. This study provides the comparison of pavement marking performances under diversified conditions. Based on accumulated pavement marking performances, this study provides performance curves based on the diversified factors. The goal of the retroreflectivity modeling is to develop equations that can be used to estimate an average retroreflectivity of pavement markings as a function time since application and traffic volume. After representing the variation of retroreflectivities and estimating regression curves by linear, exponential, logarithmic and power function, the regression curve which had the highest coefficient of determination and the value similar to the last field measurement was regarded as the retroreflectivity decay model. As a result of verification, the decay model showed the signification within the 90% confidence level and especially showed the clear relation with field data according to increase of cumulative vehicle exposure. Accordingly, these models can be used to determine service lives, retroreflectivity degradation rates, and retroreflectivity of new markings.

• Journal of Korean Academy of Nursing Administration
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• v.7 no.1
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• pp.5-14
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• 2001

To estimate total burden of hospital admission over patient of gamily, we need to know the unofficial private expenses in addition to explicit hospital admission fees. This study was conducted from June 29, 2,000 to August 10, 2,000. Subjects were 104 patient at university hospital located at chungnam province. After thorough explanation of purpose and procedures, notebooks are given to each patient or guardian. They are requested to recorded all relevant expenditures occurred during hospital stay. Incomplete records were filled-up by direct personal contact or phones. Datas were summarized and analyzed using SAS statistical package. P-value less than 0.05 was considered significant. The results of the study are as follows: 1. In 96.1% of the patient, guardians stayed at hospital to take care of patients. In 38,8% one of the family members get work-leave or temporary resting from job. Average date of leave was 7.5days. 2. Average informal cost burden per patient was 204,467 won (14,330 won${\sim}$1,594,870 won). Average hospital cost paid by the patient was 1,061,807 won. The ratio of informal cost burden to hospital cost paid by the patient was 0.327. 3. According to the regression analysis, the relevant factors affection informal cost burdens were distance from home to hospital(p=0.018), and duration of hospitalization(p=0.0001). 4. Informal cost burden was composed of expenses for personal expense of care giver (126, 720 won/patient), meal (86,924 won/patient), transportation (77,648 won/patient), necessaries of life (18,789 won/patient), tests and treatments not covered by insurance (17,289 won/patient), medical supplies not covered by insurance (15,280 won/patient), treat for visitors (14,757 won/patient), TV coin (8,247 won/patient), and others (7,582 won/patient). In addition to the hospital cost paid by the patient for hospital admission, the informal cost burdens should be recognised explicitly because it is not small. Significant proportion of informal cost burden is composed of care-giver's personal expense, transportation, meal. It is suggested that some polices are to be devised and implemented enabling that this portion of informal expenses be directed to formal professional nursing care. Thus we can improve the quality of care and decrease discomfort of patient's relatives.

• Tuberculosis and Respiratory Diseases
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• v.68 no.3
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• pp.162-167
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• 2010

Background: To date, there are few data on the risk factors for severe cases and deaths associated with the 2009 pandemic H1N1 influenza A. Here, we describe the clinical and epidemiologic characteristics of patients hospitalized for pneumonia and identify those factors associated with the development of major complications (MC). Methods: We reviewed the medical records of 41 cases of pneumonia admitted to a university-affiliated tertiary hospital between Aug 26 and Dec 10, 2009, and who had confirmed H1N1 influenza A based on real-time reverse transcriptase-polymerase-chain-reaction assay. There were 7,962 patients that fit these criteria. We compared the clinical features and demographic characteristics of patients who developed MC to with those who did not develop MC. Results: During the study period, 10 patients developed MC (required admission to the intensive care unit, n=10; required ventilator therapy, n=6; death, n=4). Patients with MC were significantly older than those without MC and more frequently had underlying medical conditions (90.0% vs 41.9%, p-value <0.01). In the patients with developed MC, the median $PaO_2/FiO_2$ ratio of 230.0 (145.0~347.3) at admission and pneumonia severity index (PSI) score of 141.5 (88.3~158.5) were higher than patients without MC. However, no differences were observed in laboratory findings or in viral shedding between the 2 groups. Conclusion: In hospitalized pneumonia patients of 2009 H1N1 influenza, old age, a history of malignancy, initial hypoxemia, $PaO_2/FiO_2$ ratio, and PSI score appear to be risk factor significantly related to developing MC. These findings might be the basis to influence strategies for admitting patients to an intensive or intermediate care unit and for pre-emptive antiviral therapy.

• Korean Journal of Agricultural and Forest Meteorology
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• v.25 no.4
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• pp.284-301
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• 2023

The changes in rice climatic yield potential (CYP) across the Korean Peninsula are evaluated based on the new climate change scenario produced by the National Institute of Agricultural Sciences with 18 ensemble members at 1 km resolution under a Shared Socioeconomic Pathway (SSP) and Representative Concentration Pathways (RCP) emission scenarios. To overcome the data availability, we utilize solar radiation f or CYP instead of sunshine duration which is relatively uncommon in the climate prediction f ield. The result show that maximum CYP(CYPmax) decreased, and the optimal heading date is progressively delayed under warmer temperature conditions compared to the current climate. This trend is particularly pronounced in the SSP5-85 scenario, indicating faster warming, except for the northeastern mountainous regions of North Korea. This shows the benef its of lower emission scenarios and pursuing more efforts to limit greenhouse gas emissions. On the other hand, the CYPmax shows a wide range of feasible futures, which shows inherent uncertainties in f uture climate projections and the risks when analyzing a single model or a small number of model results, highlighting the importance of the ensemble approach. The f indings of this study on changes in rice productivity and uncertainties in temperature and solar radiation during the 21st century, based on climate change scenarios, hold value as f undamental information for climate change adaptation efforts.