• Applied Biological Chemistry
• /
• v.50 no.2
• /
• pp.127-131
• /
• 2007

The molecular design and holographic (H) quantitative structure-activity relationships (HQSARs) on the binding affinity constants between new 3-benzylidenemyosmine analogues and nicotin acetylcholine receptors (nAChRs) of American cockroach (Periplaneta. americana L.) were studied quantitatively. The optimized HQSAR model (IV-2) for the binding affinity constants was derived from fragment distinction of hydrogene atoms in fragment size, 5${\sim}$8 bin. The statistical results of the HQSAR model (IVI-2) exhibited the best predictability and fitness for the binding affinity constants based on the cross-validated value (q$^2$=0.507) and non cross-validated value (r$^2_{nev.}$=0.944). From the graphical analyses of atomic contribution maps, it was revealed that the binding affinity constants depends upon the anabaseine ring in molecule and the most active compounds were designed by optimized HQSAR model (VI-2).

• Journal of the Korea Institute of Information Security & Cryptology
• /
• v.16 no.1
• /
• pp.71-77
• /
• 2006

Several network attacks, such as distributed denial of service (DDoS) attack, present a very serious threat to the stability of the internet. The threat posed by network attacks on large networks, such as the internet, demands effective detection method. Therefore, a simple intrusion detection system on large-scale backbone network is needed for the sake of real-time detection, preemption and detection efficiency. In this paper, in order to discriminate attack traffic from legitimate traffic on backbone links, we suggest a relatively simple statistical measure, entropy, which can track value frequency. Den is conspicuous distinction of entropy values between attack traffic and legitimate traffic. Therefore, we can identify what kind of attack it is as well as detecting the attack traffic using entropy value.

• Journal of Gastric Cancer
• /
• v.21 no.1
• /
• pp.49-62
• /
• 2021

Purpose: This study aimed to investigate the prognostic value of lymph node ratio (LNR) in patients with locally advanced gastric cancer who received neoadjuvant chemotherapy. Materials and Methods: We retrospectively enrolled gastric cancer patients treated with neoadjuvant chemotherapy and curative surgery at the First Affiliated Hospital of Zhejiang University from 2004 to 2015 as the study cohort. Patients with the same inclusion criteria treated in 2016-2017 were enrolled as the validation cohort. Kaplan-Meier curves were assessed using the log-rank test to analyze the differences in overall survival (OS). Multivariate survival analysis was performed using the Cox proportional hazards model. The areas under the receiver operating characteristic curve of ypN and LNR categories for predicting the actual 3-year OS were compared. Results: A total of 265 patients were included in the proposal cohort. The median number of retrieved lymph nodes (rLNs) was 32. The number of positive lymph nodes (pLNs) increased as rLN increased (P=0.037), but the LNR remained relatively constant (P=0.462). The LNR was categorized into 4 groups according to the prognosis: ypNr0, node-negative with rLN>25; ypNr1, node-negative with rLN≤25 or 00.3. In the validation cohort of 43 enrolled patients, there was a clear distinction in OS that significantly (P<0.001) varied depending on the LNR values and LNR was the only independent prognostic factor in multivariate analysis (P<0.001). Conclusions: LNR was an independent prognostic factor for survival of patients with gastric cancer after preoperative chemotherapy and might be an alternative predictor for ypN stage.

• Journal of Fashion Business
• /
• v.26 no.2
• /
• pp.95-109
• /
• 2022

This study was aimed at developing a new textile design based on the authentic and cultural resources of the Gangneung Subo pattern and applying the textile design to knitted fashion products. Gangneung has been recognized for its outstanding artistry in the field of Gyubang art. Gangneung Subo is an embroidered wrapping cloth. The discovered and preserved Subo at this time was from the Kwandong region centered in Gangeung, and is regarded as the product of the indigenous native culture in Kwandong. Therefore, as a representative cultural resource of Gangneung, the Gangneung Subo has sufficient value as a material for the development of cultural products with uniqueness, distinctiveness, and historicality. As a research method, the background of Gangneung Subo was investigated. A total of 12 motifs were created while preserving the authentic originality of the Gangneung Subo pattern and minimizing unwanted deformations of the pattern during the developing process. The created motifs were repeatedly applied to the pattern and new textile designs were created. Eighteen knit fashion products, including narrow and wide-width mufflers and neck warmers, were developed by applying the new textile designs. As a significant cultural resource for cultural goods development, this study ascertained the value of Gangneung Subo, preserving its unique distinction and history. This study was especially significant since the Gangneung cultural goods developed used knitted material and extended the development to producing real products.

• Journal of Fashion Business
• /
• v.28 no.2
• /
• pp.125-138
• /
• 2024

The purpose of this study is to develop and implement a step-by-step upcycling fashion education program that can be utilized within the local community. This program aims to provide basic data by analyzing the current state of community-based upcycling projects and upcycling center programs. To achieve this, the study first examined the meaning and value of upcycling in fashion through literature research and explored upcycling projects and programs in connection with local communities. Subsequently, an upcycling fashion education program platform was developed and applied using the design thinking process. The program involved students from nine high schools in Gwangju Metropolitan City. Depending on the school's circumstances, the time and difficulty level of the upcycling education program were adjusted accordingly. A unique eco-bag making kit, using jeans developed in this study, was employed. Following the completion of the program, a satisfaction survey was conducted among 167 participating students from the high school community class. The findings indicated that the majority of students experienced an increased appreciation, attraction, and interest in upcycling products. They also demonstrated an understanding of the environmental impact of upcycling products and the distinction between upcycling and recycling. It is believed that the educational program developed in this study can promote ethical fashion and foster a sense of value-based consumption. This program can be customized and flexibly adapted to different educational levels and institutional characteristics, making it accessible to a wide range of learners.

• Journal of Distribution Science
• /
• v.15 no.3
• /
• pp.61-72
• /
• 2017

Purpose - The ICT development is affecting the consumer behaviors in selecting channel or distribution system. This study aims to advance the theory on the influence and interaction with omni-channel behaviors. Specifically, analyzing moderating variable is category knowledge that effect between propensity of brand loyalty and its precedence factor which is perceived difference, perceived value, authenticity and consumer-brand relationship. Research design, data, and methodology - The subject of this research is consumers who purchase goods in omni-channel situation. The hypothesis of this research is derived from the literature of the preceding research analysis on brand loyalty, omni-channel and consumer behaviors. This study have constructs that were defined operationally with reference to previous studies, and the research model was designed to figure out the structural relationship among perceived difference, perceived value, authenticity, consumer-brand relationship and brand loyalty. From 2016 Sept. 1 to Dec. 31, a questionnaire survey was performed targeting customers using omni-channel. 327 questionnaire survey had conducted. 316 survey data were used for empirical analysis except data that had missing and wrong value. AMOS(structural equation) was used to confirm the hypothesis which developed by researcher. Results - The results of this study are as follows. First, an authenticity has significant effect on brand loyalty. Second, in the omni-channel situation, but perceived differentiation, perceived value, consumer-brand relationship does not affect brand loyalty. According to this result, it is judged that it is easy to search for information in the situation of omni-channel and integrated decision making is done without distinction between channels. Third, category knowledge has moderating effect between brand loyalty and precedence factors. When the category knowledge level is low, preceding factors have a significant effect on brand loyalty. when the category knowledge level is high, the preceding factors did not have a significant effect on brand loyalty except the authenticity. Conclusions - This study finds out omni-channel's phenomenon is different from other distribution channel phenomenon. In the situation of omni-channel, it is suggested that brand loyalty may be relatively low for a certain brand because it raises the knowledge level of the category. Then this study provides a managerial implications based on the role of the moderate effect on category knowledge, brand loyalty and omni-channel.

• Journal of the Korean Institute of Traditional Landscape Architecture
• /
• v.30 no.4
• /
• pp.81-92
• /
• 2012

The purpose of this study is to compare values, characteristics and the world heritage listed tendency of walls in East Asia. Walls in East Asia are similar by the geographically adjacent, type, form and materials, etc. Thus to demonstrate the differentiation is not easy, but walls heritage of a tentative list or listed on the UNESCO World Heritage were discriminated by the evaluation criteria of world heritage. Hidden problems are not to be described the differences by the consistent manner. So we need efforts to separate the distinction and originality of walls according to the characteristics of each heritage. As the method of this study, we reviewed the terminology associated with the wall and then have examined the following four aspects as the characteristics of each heritage category. 1) Classification according to the function and purpose, 2) Classification according to the type and size of the walls(the length of wall), 3) Classification according to the location and topography, 4) Classification according to materials and technology(construction method). And we have analyzed the tendency of OUV(Outstanding Universal Value) of the world heritage listed wall. Also we examined the value basis of the differences and similarities presented by each heritage. In the future, we should complement the following two aspects of the wall heritage in East Asia for comparing the exact value. first, we ought to come up with a system that we can easily compare the similarities and differences of similar walls heritage. Second, we have to make every effort to describe the walls heritage by considering OUV evaluation criteria to be able to share with people all around the world.

• Korean Journal of Materials Research
• /
• v.22 no.1
• /
• pp.46-53
• /
• 2012

In this study, mechanical tests and microstructural analyses including TEM analyses with EDX of precipitates in modified 9Cr-1Mo steel were carried out to determine the cause of embrittlement observed after heat-treatment, which limits the usage of the alloy for power plants. Mod. 9Cr-1Mo steel specimens at austenite temperature were quenched to the molten salt baths at $760^{\circ}C$ and $700^{\circ}C$, in which the specimens were kept for 10 min ~ 10 hr with subsequent air-cooling. Impact tests showed that the impact value dropped abruptly when the specimens were kept longer than 30 min at $\sim760^{\circ}C$ reaching to minima in about 1 hr, and then increasing at further retention. The tensile strength of the specimens reached the minimum value without much change afterward, whereas the values of elongation showed the same trend as that of the impact value. The isothermally heat-treated steel at $700^{\circ}C$ also showed a minimum impact value in about 1 hr. These results suggest that the isothermal heattreatment at 760 and $700^{\circ}C$ for about 1 hr induces temporal embrittlement in Mod. 9Cr-1Mo steel. The microstructural examination of all the specimens with extraction replica of the carbides revealed that the specimens with temporal embrittlement had $Cr_2C$, indicating that the cause of the embrittlement was the precipitation of the $Cr_2C$. In addition, TEM/EDX results showed that the Fe/Cr ratio was 0.033 to 0.055 for $Cr_2C$, whereas it was 0.48 to 0.75 for $Cr_{23}C_6$, making the distinction of the $Cr_2C$ and $Cr_{23}C_6$ possible even without direct electron diffraction analyses.

• Asia pacific journal of information systems
• /
• v.19 no.1
• /
• pp.83-111
• /
• 2009

Despite the growing emphasis on the importance of knowledge exchange among supply chain participants, few companies have fully exploited the knowledge resources held by their supply chain partners. Among many reasons for this phenomenon, recent literature on inter-firm knowledge exchange identifies knowledge complementarities between the supply channel partners as an important determinant of knowledge exchange. Firms participating in a supply chain are likely to exchange partners' complementary knowledge. In order to extract value from them, it is important to recognize the difference between the potential value and the implementation of this potential value. However, the literature fails to distinguish between potential knowledge complementarities and implemented knowledge complementarities. In order to realize the value of potential knowledge complementarities, knowledge should be exchanged and effectively integrated in the supply channel. Further, investigating inter-firm knowledge exchange from both partners' perspectives is important especially when there are interdependencies between the channel partners. The purpose of this research is to investigate the impact of potential knowledge complementarities on knowledge exchange in buyer-supplier relationships by looking at both partners' perspectives. This research also includes trust in partner's competence and inter-organizational information systems (IOIS) as they are relevant when the complementary knowledge flows between organizations. The data required for this field study was collected from 70 buyers and their suppliers in three multinational enterprises in two different industries (Automobile manufacturing and Telecommunication services) headquartered in Korea. The results indicate that potential knowledge complementarities between buyer and supplier do not directly influence knowledge exchange, but indirectly through trust in partner's competence. And the results indicate that competence-based trust and IOIS have direct effects on knowledge exchange. Empirical results also show that IOIS moderates the relationship between potential knowledge complementarities and knowledge exchange. This study is a first attempt to empirically verify the theoretical model about potential knowledge complementarities and to investigate the impact of potential knowledge complementarities on interfirm knowledge exchange. From a theoretical perspective, this study not only clarifies the distinction between potential knowledge complementarities and implemented knowledge complementarities, but also develops an instrument to measure the concept of potential knowledge complementarities in the context of operational and planning knowledge in a supply chain. Further, we develop a theoretical framework suggesting that potential knowledge complementarities of partners in a supply chain affect knowledge exchange directly and indirectly through competence-based trust. The findings from this study have some managerial implications for practicing managers as well. First, buyers should search for suppliers that have potential complementary knowledge, which can be integrated to create synergy through interfirm knowledge exchange. Furthermore, firms must develop mechanisms to identify potential complementary knowledge of partners. Second, firms should continue their endeavor to develop their own unique knowledge so that their knowledge can benefit the entire supply channel. Finally, trust among supply chain partners turns out to be an important factor for interfirm knowledge exchange. Therefore, effective management for engendering trustworthy buyer-supplier relationships should receive appropriate attention from managers.

• Proceedings of the Plant Resources Society of Korea Conference
• /
• 2020.08a
• /
• pp.101-101
• /
• 2020

Soybean is known as to have a several healthy ingredients. Among them, isoflavones are effective in reducing obesity, menopausal symptom. Isoflavones consist of 12 isomers, including Aglycon, Glucoside, Malonyl glucoside, Acetyl glucoside, and are usually found in soybean seeds. The content is determined by the sum of 12 isomers, and the content value difference between the varieties is huge. In this study, we investigated the agronomic traits, 12 isomer of isoflavone content and composition for 49 soybean germplasms. This germplasms were selected from the 23,000 germplasms with the highest total content of isoflavones possessed by the National Agrobiodiversity Center. Seed samples were cultivated in experimental field located in Jeonju City on April 04, 2019. Matured seeds were harvested and portions of each seed samples were oven-dried, pulverized, and analyzed for their isoflavone compositions using HPLC-DAD. The soybean samples showed distinction in their agronomic traits, isoflavone compositions and contents. The days to flowering ranged between 38 and 69 days while the days to maturity ranged between 103 and 156 days. The seed coat color of soybean germplasms was 24 in black, 10 in yellow, 2 in green, 5 in yellowish green, 4 in green with black spot, 4 in pale yellow. The germplasm with the highest total content of isoflavones was the IT178054(1257.61±7.98 ㎍/g), but the germplasms containing the largest number of isoflavone isomers were IT274592, IT275005, both germplasms had 11 isoflavone isomers excluding Malonyl glycitin. The largest source of Aglycon, the most easily absorbed isoflavone form in the human body, was IT274592(DZ: 8.83±0.30 ㎍/g, GL: 11.14±0.81 ㎍/g, GE: 8.16±0.26 ㎍/g), while only IT274592, IT275005, IT308619 contained all three components of Aglycon. In Principal Component Analysis(PCA), the first two principal components showed more than 3.5 Eigen value and accounted for 58.2% of variability. The total content value had strong relationship with Malonyl genistin content value. Acetyl isomers had strong relationship, but Malonyl isomers were only related to isomers except Malonyl glycitin. These results will help in research on soybean varieties to enhance isoflavone ingredients.