• Title/Summary/Keyword: Value Improvement

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Effects of the Oriental Medicinal Prescriptions, Jahyulyangeuntang and Yanghyuljangeunkeonbohwan, on Calcium Absorption in the Human Colon Carcinoma Cell Line (Caco-2 Cells) (자혈양근탕 및 양혈장근건보환이 인체 소장 상피세포주 (Caco-2) 모델에서 칼슘 흡수에 미치는 영향)

  • 박태선;임현정;황귀서
    • Journal of Nutrition and Health
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    • v.35 no.4
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    • pp.446-453
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    • 2002
  • Effects of the two oriental medicinal prescriptions, Jahyulyangeuntang (JH) and Yanghyuljangeunkeonbohwan (YH), on intestinal calcium absorption were examined in the human colon carcinoma tell line, Caco-2 cells. Intestinal calcium absorption was evaluated at the level of Ca uptake into the cells across the brush border membranes, as well as at the level of net Ca transport (implying the amount of intestinal Ca transported into the blood stream). When the Caco-2 cells were incubated for 4, 8, 16 and 24 days post seeding, the cells were differentiated continuously, and showed progressively increased activities of Ca uptake (1.13 $\pm$ 0.04, 1.19 $\pm$ 0.02, 1.94 $\pm$ 0.03, and 2.40 $\pm$ 0.12 nmole.mg protein$^{-1}$ .30 min$^{-1}$ , respectively). Pretreatment of confluent Caco-2 cells with 50 $\mu\textrm{g}$/ml of YH for 24 hours resulted in a 30% increase in Ca uptake (p < 0.07), while pretreatment of the cells with the same concentration of JH for 6 hours resulted in a 24% increase (p < 0.05) in Ca uptake, compared to the value for the control cells (2.34 $\pm$ 0.10 nmole.mg protein$^{-1}$ .30 min$^{-1}$ ). When the cells were pretreated with varied concentrations (5-100 $\mu\textrm{g}$/ml) of the test samples for 6 hours, maximal increases in Ca uptake were observed in the cells pretreated with 100 $\mu\textrm{g}$/ml of YH (a 23% increase), and 50 $\mu\textrm{g}$/ml of JH (a 28% increase), respectively : however, no influence was seen on the net Ca transport activity. These results show that pretreatment with JH or YH, the two oriental medicinal prescriptions commonly used for improvement of bone metabolism, could possibly increase Ca accumulation inside the cells. but not the intestinal Ca net transport in vitro.

Serum Carbohydrate Antigen 19-9 as an Indicator of Liver Metastasis in Colorectal Carcinoma Cases

  • Dong, Hang;Tang, Jie;Li, Long-Hao;Ge, Jun;Chen, Xin;Ding, Jing;Men, Hai-Tao;Luo, Wu-Xia;Du, Yang;Li, Cong;Zhao, Feng;Chen, Ye;Cheng, Ke;Liu, Ji-Yan
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.2
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    • pp.909-913
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    • 2013
  • Purpose: The liver is the organ to which colorectal carcinomas (CRCs) most commonly metastasize, and surgical resection has been established as the most effective and potentially curative treatment for CRC with liver metastasis (LM). Therefore, surveillance of LM is vital for improvement of prognosis of CRC patients. In this study, we aimed to explore the potential value of carbohydrate antigen 19-9 (CA 19-9), carcinoembryonic antigen (CEA), and marker enzymes in indicating LM with CRC. Methods: Three groups of eligible patients with metastatic cancers were retrospectively included: CRC patients with LM (CRC-LM) or without LM (CRC-NLM), and non-CRC patients with LM (NCRC-LM). All metastatic lesions were identified by CT or MRI. Data on characteristics of the patients, the primary site, the locations of metastasis, CA 19-9, CEA, and biochemical parameters were collected for analysis. Results: A total of 493 patients were retrospectively included. More alcohol consumption was found in CRC-LM than CRC-NLM. Some biochemical enzymes were found to be significantly higher in groups with LM than without (CRC-LM or NCRC-LM v.s CRC-NLM). Both CEA and CA 19-9 were much higher in CRC-LM than CRC-NLM or NCRC-LM. For CRC patients, CA 19-9, ${\gamma}$-glutamyl transpeptidase, CEA and alcohol consumption were identified as independent factors associated with LM. Conclusion: Our analysis suggested the CA 19-9 might be a potential valuable indicator for LM of CRC in the clinic.

Analysis of the Regional Effectiveness of Urban Wall-Planting Applied by a Biotope Area Ratio - Case of Jung-gu District in Seoul - (생태면적률 적용을 통한 도시 내 벽면녹화의 지역적 효과 분석 - 서울시 중구를 사례로 -)

  • Kang, Tae-Sun;Lee, Myung-Woo
    • Journal of the Korean Institute of Landscape Architecture
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    • v.42 no.5
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    • pp.88-100
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    • 2014
  • The purpose of the study is to analyze the regional effectiveness of wall-plantings by applying a biotope area ratio when wall-plantings are constructed in high density areas. For this, this study required a sample of the wall-planting's regional plan. Therefore, types of wall-planting were determined and applied to a sample site. Four types of wall-plantings were developed by formative features and functional features. Type "A" had simple and functional features, Type "B" had both mixed and functional features, Type "C" had both simple and landscape features and Type "D" had mixed and landscape features. Jung-gu District in Seoul was chosen as the sample site. Total investigations were performed three times for three months from June to August, 2011. Total green-able walls were located in 498 places with a total length of 8,449m and gross vertical area of $23,754.90m^2$. The classification results of total green-able walls by the four types were Type "A" at $1,936.65m^2$, Type "B" at $5,875.30m^2$, Type "C" at $12,487.85m^2$ and Type "D" at $3,455.10m^2$. This study analyzed how all facade areas of the green-able walls impacted the biotope area ratio at the site. First, the biotope area ratio regarding all the zones in Jung-gu District was defined as the gross biotope area ratio while the biotope area ratio regarding all of the artificial zones was defined as the net biotope area ratio. In the case of the gross biotope area ratio, 17.97% is current ration with a projected increase to 0.10% after wall-planting. In the case of the net biotope area ratio, 4.73% is the current ration with a projected increase to 0.11% after wall-planting. This 0.11% is about 2.28% of 4.73%. This study looks at all wall-plantings that have been constructed throughout a high density area to observe their impact on the improvement of ecological function therein. With consideration of the landscape value of the facade, the regional effectiveness of wall-planting is expected to increase even more.

Effect of Die Temperature and Dimension on Extract Characteristics of Extruded White Ginseng (사출구 온도와 구조에 따른 압출성형 백삼의 추출 특성)

  • Kim, Bong-Su;Ryu, Gi-Hyung
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.34 no.4
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    • pp.544-548
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    • 2005
  • The objective of this study was to determine the effect of die temperature and dimension on extraction pattern, extract yield, and crude saponin content of extruded white ginseng. The extrusion variables were die temperature $(110\;and\;120^{\circ}C)$ and die dimension (3 holes with 1.0 mm, 2 holes with 2.0 mm, and 1 hole with 3.0 mm diameter). The browness and redness were indicator of active components in ginseng extract. Both were used to evaluate the effect of die temperature and die dimension on release pattern and release rate constant. Browness and redness of extract achieved its lowest value at die temperature $110^{\circ}C$ and 2 holes with 2.0 mm diameter, indicating the lowest extraction rate constant. Extract yield highly increased by extrusion treatment. Extract yield and crude saponin content were the highest at die temperature $120^{\circ}C$ and 1 hole with 3.0 mm diameter. In conclusion, extrusion process has contributed significantly in improvement of release rate of its active components.

The Effect on Rats Serum Lipid of Treadmill Exercise and Green Tea Extracts Intake with High Fat Diet (고지방식이에 Treadmill운동과 녹차추출물 섭취가 흰쥐의 혈청지질에 미치는 영향)

  • 정원훈;신미경
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.4
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    • pp.683-690
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    • 2000
  • In this research high-fat-diet, which amounts to 40% out of the total calories, is prepared and taken to SD-lined rats for four weeks, and the exercise is taken using treadmill so that two groups are formed; one is for exercise group (E, EG) and the other for non-exercise group (CO,G). In addition the diet-intake-amount and body weight are measured for momparing a green tea extract intake group (EG,G) with a non-intake group (CO,E) and then serum lipid components can be analyzed after four weeks. Considering the total diet amounts for four weeks, Co group has the largest while the EG group does the smallest for the diet-intake-amounts; there is, however, no significant difference among all groups. Both body weight gain and the feed efficiency ratio of the CO group are larger than those of the EG and G group with significant differences (p<0.05). Taking into account the serum lipid components analysis, all of serum total cholesterol, LDL-cholesterol, and triglyceride of EG group have smaller values than those of non-exercise groups (CO,G) with significant differences (p<0.05) respectively, while HDL/LDL-cholesterol of EG group does a larger value than that of non-exercise groups with significant difference (p<0.05); these, hence, show efficient results. For the HDL-cholesterol level, there are no significant differences among each group and the ratio TC/HDL-cholesterol of EG group is smaller than that of Co group with a significant difference (p<0.05). Therefore, we can draw conclusions that exercise and green tea extract intake group (EG) has relatively better results than non-exercise groups (CO, G) through serum lipid components results and furthermore the effects of the green tea extracts intake is considered to play a supplementary role for the improvement of the serum lipid components.

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Evaluation of Spatial and Temporal Variations of Water Quality in Lake Shihwa and Outer Sea by Using Water Quality Index in Korea: A Case Study of Influence of Tidal Power Plant Operation (수질평가지수를 이용한 시화호 내측 및 외측 해역의 시·공간적 수질 변화 평가: 조력발전소 가동에 따른 영향 연구)

  • Ra, Kongtae;Kim, Joung-Keun;Kim, Eun-Soo;Kim, Kyung-Tae;Lee, Jung-Moo;Kim, Sung-Keun;Kim, Eu-Yeol;Lee, Seung-Yong;Park, Eun-Ju
    • Journal of the Korean Society for Marine Environment & Energy
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    • v.16 no.2
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    • pp.102-114
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    • 2013
  • The basin of Lake Shihwa is one of highly industrialized region of Korea and a current environmental issue of study area is the operation of tidal power plant (TPP) to improve water quality. The application of water quality index (WQI) which integrates five physiochemical parameters (transparency, DO, DIN, DIP and chlorophyll-a) of water quality in Lake Shihwa and outer sea during 2011~2012 were performed not only to evaluate the spatial and temporal distribution of the water quality but also to assess the effect of water quality improvement by the operation of tidal power plant. The higher WQI values were observed in monitored sites near the industrial complexes in Lake Shihwa and the outfall of wastewater treatment plants (WWTPs) in outer sea. This indicates that the quality of seawater is influenced by diffuse non-point sources from industrial, municipal and agricultural areas in Lake Shihwa and by point sources from the effluence of municipal and industrial wastewater throughout WWTPs in outer sea. Mean WQI value decreased from 53.0 in 2011 to 42.8 in 2012 of Lake Shihwa. Water quality has improved significantly after TPP operation because enhancement of seawater exchange between Lake Shihwa and outer sea leads to improve a hypoxic condition which is primarily a problem in Lake Shihwa. Mean WQI of outer sea showed similar values between 2011 and 2012. However, the results of hierarchical cluster analysis and the deterioration of water quality in summer season indicate that the operation of tidal power plant was not improved the water quality in the upper most area of Lake Shihwa. To successfully improve overall water quality of Lake Shihwa, it is urgently necessary to manage and reduce of non-point pollution sources of the basin of Lake Shihwa.

A Survey for Source Reduction and Recycling of Household Waste in Seoul Metropolitan area (도시생활쓰레기의 발생억제 및 재활용에 대한 수도권주민의식 조사분석)

  • Namkoong, Wan;Sohn, Tai-Ik
    • Journal of the Korea Organic Resources Recycling Association
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    • v.2 no.2
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    • pp.89-98
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    • 1994
  • A survey was carried out in Seoul Metropolitan area during December of 1993 and January of 1994. The objective of the survey was to provide a useful information for the development and improvement of recycling policies, regulations and systems in Korea. Of the 782 individuals contacted, 473 individuals completed and retured surveys, of which 437 were usable. The results were analyzed using a statistical package SAS(Statistical Analysis System). The results indicated that 86% of apartment area has recycling bins, while only 33% of individual house(detached dwelling) area has those. About half of the respondents felt that food waste is the major source of household waste. The most serious problem to recycle more household waste is to provide space to store recyclables at the source. The majority of Seoul Metropolitans(78.5%) are willing to participate in recycling programs, while 14.4% want to participate only when there are economic incentives or benefits. Respondents who want economic incentives appeared to be low income people. 66.1% of total respondents said that they do not use disposables. However, only 53,0% among respondents under 30 years old answered they do not use disposables. People who graduated from middle high school only and are under 30 years old have tendency to dispose of used milk cartons without rincing and drying, while those who are over 40 years old and graduated from university prefered to rinse and dry used milk cartons before disposal. Regarding disposal of newspapers, only 43.9% of the total respondents separated newspaper from other types of used paper. In the case of alumium cans, 22.5% of the total respondents answered that used aluminum cans are not recyclables. Much higher portion (30. 4%) of the respondents who graduated from middle high school only felt that aluminum cans have no value to recycle. The results indicated that education and information regarding recycling are highly desirable.

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Current Status and Future Prospect of Plant Disease Forecasting System in Korea (우리 나라 식물병 발생예찰의 현황과 전망)

  • Kim, Choong-Hoe
    • Research in Plant Disease
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    • v.8 no.2
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    • pp.84-91
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    • 2002
  • Disease forecasting in Korea was first studied in the Department of Fundamental Research, in the Central Agricultural Technology Institute in Suwon in 1947, where the dispersal of air-borne conidia of blast and brown spot pathogens in rice was examined. Disease forecasting system in Korea is operated based on information obtained from 200 main forecasting plots scattered around country (rice 150, economic crops 50) and 1,403 supplementary observational plots (rice 1,050, others 353) maintained by Korean government. Total number of target crops and diseases in both forecasting plots amount to 30 crops and 104 diseases. Disease development in the forecasting plots is examined by two extension agents specialized in disease forecasting, working in the national Agricul-tural Technology Service Center(ATSC) founded in each city and prefecture. The data obtained by the extension agents are transferred to a central organization, Rural Development Administration (RDA) through an internet-web system for analysis in a nation-wide forecasting program, and forwarded far the Central Forecasting Council consisted of 12 members from administration, university, research institution, meteorology station, and mass media to discuss present situation of disease development and subsequent progress. The council issues a forecasting information message, as a result of analysis, that is announced in public via mass media to 245 agencies including ATSC, who informs to local administration, the related agencies and farmers for implementation of disease control activity. However, in future successful performance of plant disease forecasting system is thought to be securing of excellent extension agents specialized in disease forecasting, elevation of their forecasting ability through continuous trainings, and furnishing of prominent forecasting equipments. Researches in plant disease forecasting in Korea have been concentrated on rice blast, where much information is available, but are substan-tially limited in other diseases. Most of the forecasting researches failed to achieve the continuity of researches on specialized topic, ignoring steady improvement towards practical use. Since disease forecasting loses its value without practicality, more efforts are needed to improve the practicality of the forecasting method in both spatial and temporal aspects. Since significance of disease forecasting is directly related to economic profit, further fore-casting researches should be planned and propelled in relation to fungicide spray scheduling or decision-making of control activities.

Study on Dry Matter Yields and Persistence of Forage Plants Using Cattle Feedlot Manure in Fallow Paddy Land Located in the Mid-mountain Area (퇴구비를 시용한 중산간지 휴경답에서 초종별 영속성 및 건물생산성에 관한 연구)

  • Yoon, Sei-Hyung;Ji, Hee-Chung;Lee, Sang-Hoon;Choi, Eun-Min;Jeong, Min-Woong
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.30 no.4
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    • pp.317-324
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    • 2010
  • Recently, fallow paddy land located in the mid-mountain area (FPL) due to a decrease in rice consumption has increased in some regions of our country. So, grasses and forage crops available for years in once sowing should be introduced in FPL. This study was conducted to develop the technique for cultivation of grasses and forage crops using animal manure in FPL The field experiments were carried out from 2007 to 2009 on FPL at Kumsan, Chungbuk province in Korea. Cattle feedlot manure (CFM) was prepared by mixing feces and urine of cattle with rice straw in cattle feedlot for 6 months. The experimental plots were consisted of four treatments; tall fescue-based mixed pasture applied with chemical fertilizer (Control), mono-tall fescue pasture (MTFP), tall fescue-based mixed pasture (TFBMP), mono-Perennial ryegrass (MPR-FCM), mono-Italian ryegrass (MIR-FCM), mono-Red clover (MRC-FCM) and mono-Reed canarygrass (MRCG-FCM) applied with FCM. The field of tall fescue-based pasture had been sown with a grasses mixture containing 'Fawn' tall fescue, 'potomac' orchardgrass, 'Reveille' Perennial ryegrass, and 'kenblue' Kentuky bluegrass, 'Kenland' Red clover. Seeding rates were 16, 6, 4, 2 and $2\;ha^{-1}$, respectively. DM yields of forages and rates of grass coverage was higher in MTFP, TFBMP and MRCG-FCM as compated with control treatment. This result means that FPL has contained with favorable conditions for growing grass, because forage productivity is more than 15 tons per ha per year in fallow paddy land. In addition, the farmer can save the trouble of repeated plowing and sowing every year, due to the introduction of perennial grasses. The farmer must conduct the re-seeding and induce the improvement of management methods for the elevation of the persistence of red clover and perennial ryegrass, because both red clover and perennial ryegrass having high nutritive value and palatability was less persistent. Therefore, we suggest that FPL may be the good land for forage production utilizing FCM and FCM can be applied on FPL without any negative effects on DM production and the property of soil. FPL of Korea can be better utilized by applying FCM to the mono and/or mixed swards.

Aggregate Effects on γ-ray Shielding Characteristic and Compressive Strength of Concrete (콘크리트의 감마선 차폐특성 및 압축강도에 대한 골재의 영향)

  • Oh, Jeong-Hwan;Mun, Young-Bum;Lee, Jae-Hyung;Choi, Hyun-Kook;Choi, Sooseok
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.14 no.4
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    • pp.357-365
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    • 2016
  • We observed the ${\gamma}-ray$ shielding characteristics and compressive strength of five types of concrete using general aggregates and high-weight aggregates. The aggregates were classified into fine aggregate and coarse aggregate according to the average size. The experimental results obtained an attenuation coefficient of $0.371cm^{-1}$ from a concrete with the oxidizing slag sand (OSS) and oxidizing slag gravel (OSG) for a ${\gamma}-ray$ of $^{137}Cs$, which is improved by 2% compared with a concrete with typical aggregates of sand and gravel. In the unit weight measurement, a concrete prepared by iron ore sand (IOS) and OSG had the highest value of $3,175kg{\cdot}m^{-3}$. Although the unit weight of the concrete with OSS and OSG was $3,052kg{\cdot}m^{-3}$, which was lower than the maximum unit weight condition by $123kg{\cdot}m^{-3}$, its attenuation coefficient was improved by $0.012cm^{-1}$. The results of chemical analysis of aggregates revealed that the magnesium content in oxidizing slag was lower than that in iron ore, while the calcium content was higher. The concrete with oxidizing slag aggregates demonstrated enhanced ${\gamma}-ray$ shielding performance due to a relatively high calcium content compared with the concrete with OSS and OSG in spite of a low unit weight. All sample concretes mixed with high-weight aggregates had higher compressive strength than the concrete with typical sand and gravel. When OSS and IOS were used, the highest compressive strength was 50.2 MPa, which was an improvement by 45% over general concrete, which was achieved after four weeks of curing.