• Korean Journal of Cognitive Science
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• v.2 no.1
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• pp.109-142
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• 1990

The present pater aims to review Barriers framework proposed by chomsky(1986b) to point out some potential problems and to give an alternative definition of barriers.Chomsky assumes that adjunction to non-argument is possible for syntactic movement But this assumption results in overgeneration of ungrammatical sentences.We do not allow any adjunction in syntax,and abandin the Empty Category Princile,instead we propose Head Licensing Cindition and Antecedent Condition.HLC requires empty non-proneminals to be marked by head either lexical or functional and AC states that traces should be 0-subjacent to their antecedents.

• Journal of radiological science and technology
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• v.10 no.1
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• pp.31-35
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• 1987

Authors have investigated actual conditions of 22 hospitals throughout the Seoul district to evaluate of chest radiographic systems. The results are as followed: 1. Concerning exposure factors, most hospitals have used low tube voltage, merely two hospitals high tube voltage, that is, over 120 kVp. Roughly halves of intensifying screens have been used in hospitals were medium speed screens, and the rests were high speed screens. 2, Surface doses existed within wide range of $10{\sim}63.5mR$, and image quality value were $5.60{\sim}7.49$. 3. The minimum perceptibility of Burger Phantom have been increased with contrast improvement.

• The Korean Journal of Applied Statistics
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• v.13 no.2
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• pp.447-455
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• 2000

We propose a weighted kernel pattern recognition method using the K -means clustering algorithm to reduce computation and storage required for the full kernel classifier. This technique finds a set of reference vectors and weights which are used to approximate the kernel classifier. Since the hierarchical clustering method implemented in the 'Weighted Parzen Window (WP\V) classifier is not able to rearrange the proper clusters, we adopt the K -means algorithm to find reference vectors and weights from the more properly rearranged clusters \Ve find that the proposed method outperforms the \VP\V method for the repre~entativeness of the reference vectors and the data reduction.

• Journal of the Institute of Electronics Engineers of Korea CI
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• v.38 no.5
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• pp.86-92
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• 2001

The Genetic algorithm is well known as an efficient algorithm which can solve a difficult optimization problems. Recently, there has been increasing interest in applying genetic algorithm to problems related to network design. In this paper, we propose a two step genetic algorithm for designing an optimum virtual path network(VPN) for a given physical network and traffic demand. The first step is to span route between every node pair in the network. The second step assigns VPs to minimize the total number of VPs, the number of VPs carried by a link, and the VPs hopcount. The propose algorithm is evaluated using computer simulation. The result shows that the VPN generated by the proposed algorithm is good in minimizing the number of VPs, the load on a link, and the VPs hopcount.

• Speech Sciences
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• v.8 no.2
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• pp.133-148
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• 2001

Focus and information structure are closely related with the distribution of pitch accents. A focused word conveys new information and bears a pitch accent. A content word can usually get a pitch accent, but it can be deaccented if it is mentioned earlier in the discourse. In this paper, we test how English native speakers and Korean learners of English realize pitch accents according to focus and information structure of a sentence. The production experiment shows that English native speakers give a pitch accent to narrow-focused items, deaccenting all the other items of the sentence. For VP broad focus, native speakers give a pitch accent either to both the verb and its complement or to the complement only. On the other hand, it is found that Koreans give pitch accents to most content words regardless of focus and information structure. Moreover, the perception experiment confirms that Koreans' intonation patterns, which are not appropriate in terms of focus and information structure, may jeopardize listeners' comprehension. This paper shows that Korean speakers have little knowledge about focus and information structure for intonational realization, and that such notions should be applied to teaching of English intonation.

• Proceedings of the Korean Society of Applied Pharmacology
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• 2003.11a
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• pp.70-70
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• 2003

Estrogen receptor is a ligand-activated transcription factor. Its action depends on the receptor, its ligand, and its coactivator proteins. As a consequence, the concentration of the receptor is a major component that governs the magnitude of the estrogen response. Despite the extensive knowledge on mechanism of estrogen receptor action, regulation of estrogen receptor itself is not very well understood. Estrogen receptor is known to be downregulated under hypoxia leading to inhibition of estrogen receptor mediated transcription activation. We have studied mechanism of loss of estrogen responsiveness under hypoxia. We found that Hif-l${\alpha}$, a major transcription factor regulating hypoxic response, inhibited transcription of estrogen response element driven luciferase gene by expression of HIF-l${\alpha}$/vp16 construct designed to contain transcription activity under normoxia. This loss of estrogen responsiveness appears to be the result of ER${\alpha}$ downregulation. ER${\alpha}$was downregulated at the levels of ligand-biding and protein within l2-24h, and the response was blocked by the proteasome inhibitor MG132, protein synthesis inhibitor cyclohexamide, and tyrosine kinase inhibitor Genistein. These results demonstrate that Hif-l${\alpha}$ downregulates ER${\alpha}$ by proteasome dependent pathway.

• Biomolecules & Therapeutics
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• v.24 no.5
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• pp.552-558
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• 2016

Severe complications associated with EV71 infections are a common cause of neonatal death. Lack of effective therapeutic agents for these infections underlines the importance of research for the development of new antiviral compounds. In the present study, the anti-EV71 activity of norwogonin, oroxylin A, and mosloflavone from Scutellaria baicalensis Georgi was evaluated using a cytopathic effect (CPE) reduction method, which demonstrated that all three compounds possessed strong anti-EV71 activity and decreased the formation of visible CPEs. Norwogonin, oroxylin A, and mosloflavone also inhibited virus replication during the initial stage of virus infection, and they inhibited viral VP2 protein expression, thereby inhibiting viral capsid protein synthesis. However, ribavirin has a relatively weaker efficacy compared to the other drugs. Therefore, these findings provide important information that will aid in the utilization of norwogonin, oroxylin A, and mosloflavone for EV71 treatment.

• Korean Journal of Computational Design and Engineering
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• v.21 no.2
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• pp.159-169
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• 2016

In order to realize the virtual prototyping (VP) of digital products, it is important to provide the people involved in product development with the appropriate visualization and interaction of the products, and the vivid simulation of user interface (UI) behaviors in an interactive 3D virtual environment. In this paper, we propose an approach to web-based 3D virtual experience using Unity and Leap Motion. We adopt Unity as an implementation platform which easily and rapidly implements the visualization of the products and the design and simulation of their UI behaviors, and allows remote users to get an easy access to the virtual environment. Additionally, we combine Leap Motion with Unity to embody natural and immersive interaction using the user's hand gesture. Based on the proposed approach, we have developed a testbed system for web-based 3D virtual experience and applied it for the design evaluation of various digital products. Button selection test was done to investigate the quality of the interaction using Leap Motion, and a preliminary user study was also performed to show the usefulness of the proposed approach.

• Proceedings of the KSPS conference
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• 1996.10a
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• pp.198-206
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• 1996

Using eighteen text materials from various goners of present-day Japanese, we collected phonologically reduced forms frequently observed in conversational Japanese, and classified them in search of unified explanation of phonological reduction phenomena. We found 7,516 cases of reduced forms which we divided into 43 categories according to the types of phonological changes they have undergone. The general tendencies ale that deletion and fusion of a phoneme or an entire syllable takes place frequently, resulting in the decrease in the number of syllable. Typical examples frequently observed throughout the materials are : $~/noda/{\rightarrow}~/nda/,{\;}-/teiru/{\rightarrow}~/teru/,{\;}~/dewa/{\rightarrow}~/zja/,{\;}~/tesimau/{\rightarrow}~/cjau/$. From morphosyntactic point of view phonological reduction often occurs at the NP and VP morpheme boundaries. The following findings are drawn from phonological observations of reduction. (1) Vowels are more easily deleted than consonants. (2) Bilabials(/m/, /b/, and /w/ are the most likely candidates for deletion. (3) In a concatenation of vowels, closed vowels are absorbed into open vowels, or two adjacent vowels come to create another vowel, in which case reconstruction of the original sequence is not always predictable. (4) Alveolars are palatalized under the influence of front vowels. (5) Regressive assimilation takes place in a syllable starting with ill, changing the entire syllable into phonological choked sound or a syllabic nasal, depending on the voicing of following phoneme.

• Korean Journal of Computational Design and Engineering
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• v.18 no.5
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• pp.359-366
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• 2013

In the lower arm design process, a tolerance optimization of the variance of design variables should be preceded before manufacturing process, since it is very cost-effective compared to a strict management of tolerance of products. In this study, a design of experiment (DOE) based on response surface model (RSM) was carried out to find optimized design variables of the lower arm, which can meet a given requirement of probability constraint for the process capability index (Cpk) of the weight and maximum stress. Then, the design space was explored by using the central composite design method, in which the 2nd order Taylor expansion was applied to predict a standard deviation of the responses. The optimal solutions satisfying the probability constraint of the Cpk were found by considering both of the mean value and the standard deviation of the design variables.