• Korean Journal of Radiology
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• 제25권8호
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• pp.767-768
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• 2024

• Korean Journal of Radiology
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• 제21권9호
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• pp.1045-1054
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• 2020

Objective: This study aimed to evaluate the diagnostic value of combining the quantitative parameters of shear wave elastography (SWE) and superb microvascular imaging (SMI) to breast ultrasound (US) to differentiate between benign and malignant breast masses. Materials and Methods: A total of 200 pathologically confirmed breast lesions in 192 patients were retrospectively reviewed using breast US with B-mode imaging, SWE, and SMI. Breast masses were assessed based on the breast imaging reporting and data system (BI-RADS) and quantitative parameters using the maximum elasticity (Emax) and ratio (Eratio) in SWE and the vascular index in SMI (SMI_VI). The area under the receiver operating characteristic curve (AUC) value, sensitivity, specificity, accuracy, negative predictive value, and positive predictive value of B-mode alone versus the combination of B-mode US with SWE or SMI of both parameters in differentiating between benign and malignant breast masses was compared, respectively. Hypothetical performances of selective downgrading of BI-RADS category 4a (set 1) and both upgrading of category 3 and downgrading of category 4a (set 2) were calculated. Results: Emax with a cutoff value of 86.45 kPa had the highest AUC value compared to Eratio of 3.57 or SMI_VI of 3.35%. In set 1, the combination of B-mode with Emax or SMI_VI had a significantly higher AUC value (0.829 and 0.778, respectively) than B-mode alone (0.719) (p < 0.001 and p = 0.047, respectively). B-mode US with the addition of Emax, Eratio, and SMI_VI had the best diagnostic performance of AUC value (0.849). The accuracy and specificity increased significantly from 68.0% to 84.0% (p < 0.001) and from 46.1% to 79.1% (p < 0.001), respectively, and the sensitivity decreased from 97.6% to 90.6% without statistical loss (p = 0.199). Conclusion: Combining all quantitative values of SWE and SMI with B-mode US improved the diagnostic performance in differentiating between benign and malignant breast lesions.

• Journal of Plant Biology
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• 제6권3호
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• pp.6-14
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• 1963

삼배체 및 사배체 호맥종자를 중성자 및 감마선에 조사해서 파종하고 발아과정, 지상부와 지하부의 성장, 건중량의 배가 등을 조사하였다. 특히 종자함수량이 방사선감수성에 대한 역할을 관찰하였다. 사배체호맥은 이배체의 그것 보다 속중성자의 조사에 대해서 지항성이 더 강했다. 지하부는 이부체호맥에 있어서는 1120 rads, 사배체에 있어서는 1400 rads 이하인데 지하부 보다 중성자조사에 대한 감수성이 높았다. 조사량이 낮을 때는 건중량성장이 촉진되는 효과가 있었다. 종자함수량이 낮을수록 방사선감수성이 배가했으나 함수량이 28%에 달했을 때 다시 회복되어서 높아졌다. 조사시 종자함수량이 23%를 초과하였을 때에는 6 K rads의 조사량에 있어서 지하부의 신장성장이 촉진되는 현상이 나타났고 지하부의 건중량성장과 조사시의 종자함수량과의 관계는 사배체 호맥 보다는 이배체호맥이 더 큰 영향을 받는다는 사질을 보았다. 지하부의 신장량의 반감을 초래하는 조사량단위를 기준으로 할 때 N/X의 effectiveness ratio는 이배체호맥에 있어서는 약 20.0 이였고 사배체호맥은 약 18.2 였다.

• 대한화학회지
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• 제16권2호
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• pp.80-83
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• 1972

The activity change of lysozyme resulted from its exposure to $Ti-H_2O_2$system in aqueous liquid at room temperature and to ${\gamma}$-irradiation in ice at $195^{\circ}K$ has been measured at room temperature with a Cary-14 spectrophotometer. The enzymatic activity of lysozyme which had been added to a previously flow-mixed solution of $TiCl_3$ and $H_2O_2$ (System I) was compared with the activity of a lysozyme-$H_2O_2$ solution after flow-mixing with $TiCl_3$ (System II), considering the differences between these two activity changes as the extent of the enzymatic inactivation by the involvement of OH radical reaction. The fraction of lysozyme inactivated by OH radical in the system containing 0.0025 M $TiCl_3-0.1M$ $H_2O_2$ (ph 3.5) was 13%, When the $TiCl_3$ concentration is double (pH 3.0), the fraction of enzyme inactivated increases to 36%. The activity of the system containing 0.025 M $TiCl_3-0.1$ M $H_2O_2$ (pH 1.5) was essentially zero. The results seem to support the previos view that the production of OH radical should be proportional to $TiCl_3$ concentration when $H_2O_2$ is present in excess. Increase in the extent of inactivation found in system I with increasing $TiCl_3$ concentration may be due to a pH effect. $H_2O_2$ seems to be less effective than $TiCl_3$ in the inactivation. 1% lysozyme solution, when ${\gamma}$-irradiated with a total dose of 3M rads, loses about 20% of its activity. Lowering of temperature also was found to yield a reduction in enzymatic activity.