• Korean Journal of Food Science and Technology
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• v.35 no.4
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• pp.713-719
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• 2003

The effects of butanol (BuOH) fraction of Alisma canaliculatum (Ac) with vitamin E in streptozotocin (STZ)-induced diabetic rats were determined. Sprague-Dawley rats were divided into 5 groups: normal, STZ-control, and 3 diabetic-experimental groups. Diabetes mellitus was induced by injection of STZ (45 mg/kg) into the tail vein. The BuOH fraction of Ac and vitamin E were administrated orally in experimental rats for 21 days: Ac group (400 mg/kg), Ac-VE group (Ac 400 mg/kg & vitamin E 10 mg/kg), and VE group (vitamin E 10 mg/kg). The body weight losses were seen in all groups except normal, and the decrements in experimental groups were less than that in diabetic-control group. The plasma glucose levels were significantly lower in Ac group compared to STZ-control group on 21 day (p<0.05). The plasma level of insulin was slightly higher in AC-VE group than other diabetic groups. The plasma cholesterol levels of diabetic-experimental groups were significantly lower than those of STZ-control group on 14 day (p<0.05). ALT and AST activities of diabetic-experimental groups were significantly lower than that of STZ-control group (p<0.05). The results suggested that the BuOH fraction of Ac might possess hypoglycemic properties in STZ-induced diabetic rats and no synergistic effect of vitamin E was seen during the experimental period.

• Journal of Korean Society for Quality Management
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• v.19 no.2
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• pp.108-116
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• 1991

Value Engineering has been recognized by many companies as a powerful and innovative techniques approach for cost down and improvement in function of product and service. Functional evaluation is the most important progress in VE activities. But it is often difficult to evaluate the function of a certain subject because the evaluation of function is very vague. This paper presents a new functional evaluation method using fuzzy theory. The purpose of this proposed method is the improvement in the precision of functional evaluation.

• Journal of the Korean Institute of Landscape Architecture
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• v.30 no.6
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• pp.79-97
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• 2003

The purpose of this paper is to analyze a causal model determining social carrying capacity(SCC) in natural parks, to answer the research question: What is the mechanism for determining SCC in natural parks (NP)\ulcorner After reviewing the literature on SCC and recreation activities in Korean natural parks, we constructed a conceptual framework and formulated the hypothesis of this research. We obtained data through a questionnaire which surveyed 487 visitors at 6 of the 73 NP in Korea during 2001, based on a stratified sampling method. We analyzed the data using descriptive statistical methods, the mean difference test, Pearson's correlation analysis, and path analysis method. We found that 1) The direct effect of resources, activity space(AS), visitor's expectation(VE), encounter, crowding, damage of resources(DR), maintenance condition of resources and facility(MCRF) to SCC are 3.45, 3.62, 2.75, 2.72, 1.32, and 4.77 times more important than that of crowding, respectively, while the indirect effect of resources, AS, VE, encounter, and DR to SCC is 13.03, 11.19, 3.34, 1.3, 2.05, 1.10, 0.05 and 2.30 times more important then that of crowding, respectively, 2) Causal effects of resources, facility, AS, VE, number of visitors(NV), encounter, crowding, VM, DR, and MCRF to SCC turned out to have 0.3523, 0.3321, 0.1751, 0.1465, 0.0307, 0.0762, 0.0604, -0.0510, -0.1177 and 0.2165, respectively, and 3) The causal effect of activity base(AB) and activity atmosphere(AA) to SCC turned out to have 2.57 and 1.1 times higher than that of MCRF, respectively. The research results suggest that 1) this conceptual framework is highly useful for the development of substantive theory and methodology; 2) management issues of AA and MCRF turned out to have 0.81 times in SCC that of AB, i.e, SCC can be significantly improved from control of AA and MCRF; and 3) supply of excellent resources and convenient facilities is needed to increase social carrying capacity. It is recommended that more empirical studies be performed in the future according to the season, visitor characteristics, and AS by NP.

• International conference on construction engineering and project management
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• 2009.05a
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• pp.1625-1629
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• 2009

The new paradigm called 'Low Carbon Green Growth' involved in reducing greenhouse gas is on the rise as a critical issue worldwide. The essential of Kyoto protocol issued in 1997 is to achieve the sustainable economic growth environments by converting existing production system to eco-friendly one. The protocol imposes the liability to reduce greenhouse gas to the countries joined to it. The paradigm is directly involved in the energy consumption and environmental pollution caused by construction activities. Value Engineering which are mainly applied in the design phase in practice is a measure to improve the value of a constructed facility by analyzing and/or appraising the functions and costs of it. However, an appropriate method which assesses eco-friendliness of constructed facility has not been propose by researchers. This paper proposes a method which assesses the performance involved in eco-friendliness of constructed facility using Value Engineering (VE) in the design phase. The method estimates the environmental cost relative to the amounts of energy consumption and environmental pollution occurred over the entire project life cycle. The database called "Life Cycle Inventory DB", which stores information about the amounts of environmental pollution, is used. The algorithm which retrieves the amounts of environmental pollutions from the DB and converts them into environmental costs is developed. The algorithm is implemented into a system which quantifies the eco-friendliness of constructed facility in the design phase using VE.

• Korean Journal of Cognitive Science
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• v.17 no.4
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• pp.357-373
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• 2006

Virtual reality (VR) provides a virtual experiment (VE) context consisting of information presented to the senses of the user. The user perceiver and interprets the VE context, and then naturally recognizes a level of realism in the VE. Presence is often thought of as the sense of 'being there' in the n. Presence includes overall feelings about the information conveyed from a virtual avatar to the user. Therefore, there must be brain mechanisms for integrating sensory information about presence.'Feeling of presence' is related with the user's cognition and perception about information on communication through medium. Thus 'feeling of presence' may characterize perceptual mechanisms in the brain. We studied these mechanisms by presenting a VR that consisted of an avatar telling a story about a social conversation. We performed covariance analysis on subjective brain activity (fMRI) during the story presentation with a presence score. The data analysis revealed that activity in several brain areas was correlated with the presence store. A positive correlation was shown in the right lingual gyrus, right cuneus, left lingual gyrus, right fusiform gyrus, left inferior temporal gyrus, anterior cingulate cortex and right posterior cingulate cortex of the brain. This study showed the brain mechanism to be related the feeling of presence and brain activities in our subjects, using VR to communicate information.

• Sijohaknonchong
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• v.24
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• pp.259-278
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• 2006

In this study, I've researched the sijo written by Yukdang, Choi, Nam Sun, and Manhae. Han, Yong Woon who were the leading intellectual and the pioneers experiencing the time of flowering and the colonial period. Their lives had the common things in various way. They were involved in Independence movement as the intellectual at that time. They also showed the various activities such as modern poem. sijo, and even Chinese poetry. In this thesis, 1 compared their sijo and considered them. Especially, I've researched the two divided parts focused on the tone shown in the sin one part was focused on the 'lover', and the other was on the 'life'. The summarise which I've researched is as followings. First, I've researched the sijo focused on the 'lover' They have the common things in having the presupposition of farewell to their 'lover'. But there were significant differences as followings. In the case of Yukdang, he expressed the passive tone based upon the despondency and the loss with the absence of his lover. Meanwhile, Manhae tended to reveal the resigned and negative tone based to his lyrical world. The contrasted tone in their poems is considered to have something to do with their realistic matters. There should also be several things to be discussed in the future.

• Archives of design research
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• v.21
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• pp.1-12
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• 1997

This research is that it could use a theory from a .cognitive science, making a hypothesis to explain the thingking steps of designing, adapting the problem solving of the design from knowledge of a cognitive science, to meet the possiblity which it can be developed the new way of the thinking. Design is a field where it needs a complexity with hi-brain activities. And cognitive science is a science which it study human brain activities. However, it is also quite possible to bo adaped over all design by linking with design and cognitive science. I explaned the ideation of the thinking steps on this study by the knowledge of cognitive science, to observe to be possible. I found out the new ways of possibilities from design thinking process. It is a result that I've been interpretated the design process and the thinking process out of the theory of knowledge structure.

• The Korean Journal of Food And Nutrition
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• v.32 no.5
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• pp.553-559
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• 2019

To investigate the effects of antioxidant activities and hair loss prevention of extracts from Platycodon grandiflorum, we've prepared chloroform (CF) and ethylacetate fractions (EA) extracted from P. grandiflorum. In the results of DPPH radical scavenging assay, the two fractions showed dose-dependent antioxidant activities. Furthermore, in the ABTS assay, the two fractions exhibited the inhibitory effect over 90% at 10, 50, 100, 200 mg/mL. To investigate the inflammation inhibitory effect, we used RAW264.7 cells, these extracts were inhibited inflammatory reaction by suppressing the production of nitric oxide (NO) and prostaglandin $E_2$ ($PGE_2$) in dose-dependent manner. In the assay of HaCaT cells' proliferation, the 24 hr treatment of the extracts significantly accelerarted cell proliferation in the range of concentrations used. The two fractions inhibited the proliferation of Malssezia furfur, the bacteria induce the dandruff. Finally, the CF could significantly inhibit the DHT production at 1, 10, 50, $100{\mu}g/mL$, but EA showed the inhibitory effect at the concentration over $50{\mu}g/mL$. The overall results of this study suggest that the chloroform (CF) and ethylacetate fractions (EA) from P. grandiflorum could be a useful raw material for the hair loss prevention products.

• Journal of Veterinary Clinics
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• v.34 no.3
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• pp.172-177
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• 2017

Fucoidan, a cell wall polysaccharide found in the brown seaweed, is reported to have broad-spectrum biological activities. The objectives of this study were to examine the effect of fucoidan on prostaglandin $E_2$ ($PGE_2$) and cyclooxygenase-2 (COX-2) expression in lipopolysaccharide (LPS)-stimulated porcine peripheral blood mononuclear cells (PBMCs) and to determine whether these effects are involved in Akt activation. The levels of $PGE_2$ production in the culture supernatants from PBMCs were determined by the enzyme-linked immunosorbent assay (ELISA) kit and the levels of COX-2 mRNA were measured by real time polymerase chain reaction (RT-PCR). Akt activity was determined by Western blot analysis. Fucoidan in LPS-$na{\ddot{i}ve}$ PBMCs has no effect on $PGE_2$ production and COX-2 mRNA expression. Furthermore, fucoidan does not affect Akt activation in LPS- $na{\ddot{i}ve}$ PBMCs. However, $PGE_2$ production and COX-2 mRNA expression on PBMCs were remarkably enhanced by LPS stimulation. Akt activity was also increased by LPS. Increasing effects of $PGE_2$ production and COX-2 mRNA expression in PBMCs induced by LPS were suppressed by addition of fucoidan. In addition, fucoidan reduced an increase in Akt activity in LPS-stimulated PBMCs. These results suggested that fucoidan exerts potent anti-inflammatory properties by suppression of $PGE_2$ production, COX-2 mRNA expression and Akt activation in LPS-stimulated PBMCs.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.34 no.6
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• pp.1937-1944
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• 2014

In recent years, common ducts have been installed and operated in the sidewalls of tunnels to prepare for emergencies in tunnel construction and maintenance. The installation of common ducts is done mainly by humans. Problems with cost increases are inherent in tunnel construction by humans due to the safety risks and the economic inefficiency of humans performing construction activities. Among the problems that arise are poor illumination due to the use of temporarily installed electricity, the risk of accidents due to the confined workspaces, and workers avoiding work tasks because of the poor environment in tunnel. Ideas for solving these problems were developed using a value engineering (VE) process, and mechanized construction was identified as a promising solution. To verify the effectiveness of mechanized construction of a common duct in tunnels, experimental construction work was carried out, and mechanized construction was proven to directly improve the constructability and economic efficiency of common duct construction. In addition, reducing human involvement in common duct construction in tunnels is expected to improve safety, and because of the continuous concrete placement technique used, the finish and appearance of the ductwork are improved.