• Journal of Microbiology
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• v.45 no.5
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• pp.441-446
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• 2007

HIV-1 coreceptor usage and phenotype mainly determined by V3 loop are associated with the disease progression of AIDS. Predicting HIV-1 coreceptor usage and phenotype facilitates the monitoring of R5-to-X4 switch and treatment decision-making. In this study, we employed random forest to predict HIV-1 biological phenotype, based on 37 random features of V3 loop. In comparison with PSSM method, our RF predictor obtained higher prediction accuracy (95.1% for coreceptor usage and 92.1% for phenotype), especially for non-B non-C HIV-l subtypes (96.6% for coreceptor usage and 95.3% for phenotype). The net charge, polarity of V3 loop and five V3 sites are seven most important features for predicting HIV-1 coreceptor usage or phenotype. Among these features, V3 polarity and four V3 sites (22, 12, 18 and 13) are first reported to have high contribution to HIV-1 biological phenotype prediction.

• Proceedings of the KIPE Conference
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• 2001.10a
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• pp.466-469
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• 2001

In this paper, closed loop V/f control of induction motor has been implemented by the estimated speed. Closed loop V/f control improve the performance of induction motor drive system at low speed compared to open loop V/f control. However, closed loop V/f control need speed sensor. By using the estimated speed, closed loop V/f control is possible without speed sensor. Rotor speed is calculated from the difference between synchronous frequency and slip angular frequency. 3-phase voltage reference is obtained from synchronous frequency. And the PWM technique using space vector PWM is applied in this scheme. In the space vector PWM, effective time of 3-phase voltage reference is used to simplify the calculation of effective voltage time. This scheme is simple to implement and one chip microprocessor was used in experimental system.

• Animal cells and systems
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• v.12 no.3
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• pp.137-141
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• 2008

Molecular cloning revealed the three isoforms($Ca_v3.1,\;Ca_v3.2,\;and\;Ca_v3.3$) of the T-type calcium channel subfamily. Expression studies exhibited their distinctive electrophysiological and pharmacological properties, accounting for diverse properties of T-type calcium channel currents previously characterized from isolated cells. However, electrophysiological properties of ion channels have shown to be more diversified by their splice variants. We here searched splice variants of rat $Ca_v3.1$ T-type channel by reverse-transcription-polymerase chain reaction(RT-PCR) to further explore diversity of $Ca_v3.1$. Interestingly, analyses of cloned RT-PCR products displayed that there were at least four splicing variants of rat $Ca_v3.1$ in the loop connecting repeats III and IV. Southern blot analyses indicated that the predominantly detected variant in brain was $Ca_v3.1a$(492 bp), which were rarely detected in most of peripheral tissues. Other two variants($Ca_v3.1c$, 546 bp; $Ca_v3.1d$, 525 bp) were detected in most of the tissues examined. The smallest isoform($Ca_v3.1b$, 471 bp) was rarely detected all the tissues. Electrophysiological characterization of the splicing variants indicated that the splice variants differ in inactivation kinetics and the voltage dependence of activation and inactivation as well.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.21 no.4
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• pp.80-87
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• 2007

This paper will suggest that the 1 cross orthogonal loop type sensor improves on the orthogonal loop form sensor-head, which is available a calibration of the linear birefringence, when a fiber optic current sensor was composed. An output characteristics of the 1 cross orthogonal loop form, a general closed loop form, the orthogonal loop form are compared by the IEC(International Electrotechnical Commission) 60044-8 standard, and the state of polarization is compared with three forms. As a result, when the closed loop form was changed to the orthogonal loop form, retardation decreased 15.3[%]. When the closed loop form was changed to the 1 cross orthogonal loop type, the retardation decreased 33.8[%]. As a result of the Faraday Effect measurement, the 1 cross orthogonal loop form has the highest output characteristic and the lowest error ratio. It met the 0.5 class of the IEC 60044-8 standard. Thus, in application of the 1cross orthogonal loop form, the possibility to develop high reliability fiber optic current sensors that have a high output and stable error ratio rises is increased.

• Proceedings of the KIPE Conference
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• 2000.07a
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• pp.485-488
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• 2000

In this paper dynamic analyses and control design of a step-down switched-capacitor dc-dc converter are presented. Open-loop dynamics of the converter are analyzed using the stage-space averaging technique. A systmatic control design method that offers excellent closed-loop performance for the converter is proposed, The analysis results and dynamic performance of the converter are verified using 18 W experimental converter that delivers a 5V/3.5V output from a 11-16V input source.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.15 no.2
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• pp.89-94
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• 2022

In this paper, a discrete-time loop filter(DLF) phase-locked loop with a Frequency Fluctuation Converting Circuit(FFCC) has been proposed. Discrete-time loop filter can improve spur characteristic by connecting the charge pump and voltage oscillator discretely unlike a conventional continuous-time loop filter. The proposed PLL is designed to operate stably by the internal negative feedback loop including the SSC acting as a negative feedback to the discrete-time loop filter of the external negative feedback loop. In addition, the phase noise is further improved by reducing the magnitude of the loop filter output voltage variation through the FFCC. Therefore, the magnitude of jitter has been reduced by 1/3 compared to the conventional structure. The proposed phase locked loop has been simulated with Hspice using the 1.8V 180nm CMOS process.

• Journal of Electrical Engineering and Technology
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• v.3 no.4
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• pp.559-565
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• 2008

This study designed a new type of loop antenna that is able to detect partial discharges based on microstrip line technology. In the diagnosis of power cables, partial discharge signals are generally produced at a frequency range less than 100MHz because high frequency PD signals are lost along a propagation path in such cables. The new type of loop antenna sensor has been studied using simulation software known as CST microwave studio version 5.0. In partial discharge measurement experiments, a commercial HFCT sensor was used as a reference sensor. Several experiments were made over HFCT and loop antenna sensors for detecting partial discharges on 22.9kV MV XLPE cable. In this study, we showed the loop antenna designed in this study that can be applied as a commercial HFCT sensor.

• The Journal of Korean Society of Virology
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• v.26 no.2
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• pp.251-258
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• 1996

The V3 loop, a hypervariable domain of envelope glycoprotein, has an essential role in viral infectivity and has a major epitope for type-specific neutralizing antibody. In order to investigate genetic diversity of V3 region of gp120 of human immunodeficiency virus type 1 (HIV-1) isolated from Korean patients, DNA sequences encoding the C2 to V3 region were amplified by nested polymerase chain reaction (PCR) from uncultured peripheral blood mononuclear cells obtained from 15 HIV-1 seropositive patients and nucleotide sequences were determined. All nucleotide sequences from fifteen patients were compared with 8 distinctive subtypes (A-H) and another subtype O. Phylogenetic analysis was carried out with PHYLIP ver 3.5 (Dnapars) program. Of the 15 isolates, 14 HIV-1 subjects were clustered with subtype B, while one was clustered with subtype C. Intra-subtype B distance at the nucleotide and deduced amino acid level were maximum 17.7% and 37.0%, respectively. Intra-patient distance at the nucleotide and deduced amino acid level were maximum 7.3% and 17.8%, respectively. Analysis of the nucleotide sequences revealed that Korean types have relatively well conserved sequences. These findings could be useful for assessing the source of infection and developing an AIDS vaccine.

• Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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• 2001.07a
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• pp.58-61
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• 2001

Metal-insulator-semiconductor (MIS) C-V properties with high dielectric AIN thin films showed no hysteresis and good interface properties. The dielectric constant of the AIN film calculated from the capacitance at the accumulation region in the capacitance-voltage(C-V) characteristics was about 8. The C-V characteristics of MFIS capacitor showed a hysteresis loop due to the ferroelectric nature of the LiNbO$_3$ thin films. Typical dielectric constant value of LiNbO$_3$ film of MFIS device was about 23. The memory window width was about 1.2V at the gate voltage of $\pm$5 V ranges. Typical gate leakage current density of the MFIS structure was the order of 10$^{-9}$ A/cm$^2$ at the range of within $\pm$500 kV/cm. The ferroelectric capacitors showed no polarization degradation up to about 10$^{11}$ switching cycles when subjected to symmetric bipolar voltage pulse(peak-to-peak 8V, 50% duty cycle) in the 500kHz.

• Journal of the Korean Ceramic Society
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• v.15 no.2
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• pp.79-84
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• 1978

$Zn_{0.105}Co_{0.025}Li_{0.435-1/2x}Ni_x Fe_{2.435-1/2x-y }Mn_y O_4$ 조성의 메모리코어 특성과 $Nb_2O_5$ 및 $V_2O_5$의 소량 첨가가 square-loop성질에 주는 영향을 연구하였다. 위의 조성에서 닉켈의 양 x는 0에서 0.15까지, 그리고 망간의 양 y는 0.05에서 0.25까지 변화시켰다. $Nb_2O_5$와 $V_2O_5$의 양은 각각 위의 화학식에 대하여 0.005에서 0.015까지 변화시켰다. 실험결과에 의하면 $Mn^{+3}$를 octahedral자리에 첨가하였을 때에는 잡음이 감소되었고 메모리코어 squareness와 보자련의 온도계수가 증가하였다. 닉켈을 첨가하였을 때에는 메모리코어의 squareness와 잡음이 증가하였다. $Nb_2O_5$를 소량 첨가하였을 때에는 square-loop성질이 개선되었음에 비하여 $V_2O_5$를 소량 첨가하였을 때에는 square-loop성질이 나빠졌다.