• Tuberculosis and Respiratory Diseases
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• v.42 no.6
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• pp.900-912
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• 1995

Background: Although graded exercise stress tests are widely used for the evaluation of cardiorespiratory performance, normal standards on respiratory gas exchange and ventilatory functions at maximal exercise in Koreans have not been well established. The purpose of this study is to provide reference values on these by sex and age, along with derivation of some of their prediction equations. Method: Symptom-limited maximal exercise test was carried out by Bruce protocol in 1,000 healthy adults consisting of 603 males and 397 females, aged 20~66 years. Among them VC, $FEV_1$ and MVV were also determined in 885 cases. All the subjects were members of a health center, excluding athletes. During the exercise, subjects were allowed to hold on to front hand rail of the treadmill for safety purpose. Results: The $VO_2\;max/m^2$, $VCO_2\;max/m^2$ and $V_E\;max/m^2$ were greater in males than in females and decreased with age. The RR max in men and women was similar but decreased slightly with age. The $V_T$ max was markedly greater in men but showed no significant changes with age in either gender. The mean of $V_T$ max/VC, $V_E$ max/MVV and BR revealed that there were considerable ventilatory reserves at maximal exercise even in older females. The regression equations of the cardinal parameters obtained using exercise time(ET, min), age(A, yr), height(Ht, cm), weight(W, kg), sex(S, 0=male; 1=female), VC(L), $FEV_1$(L) and $V_E$ max(L) as variables are as follows: $VO_2\;max/m^2$(L/min)=1.449+0.073 ET-0.007A+0.010W-0.006Ht-0.209S, $VCO_2\;max/m^2$(L/min)=1.672+0.063ET-0.008A+0.010W-0.005Ht-0.319S, VE max/$m^2$(L/min)=58.161+1.503ET-0.315A-9.871S or VE max/$m^2$(L/min)=47.873+6.548 $FEV_1$-5.715 S, and VT max(L)=1.497+0.223VC-0.493S. Conclusion: Respiratory gas exchange and ventilatory variables at maximal exercise were studied in 1,000 non-athletes by Bruce protocol. During exercise, the subjects were allowed to hold on to hand rail of the treadmill for safety purpose. We feel that our results would provide ideal target values for patients and healthy individuals to be achieved, since our study subjects were members of a health center whose physical fitness levels were presumably higher than ordinary population.

• Journal of Astronomy and Space Sciences
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• v.8 no.1
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• pp.99-113
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• 1991

We developed a software system called IODS(ISSA Orbit Determination System), which can predict the orbit of arbitary artificial satellite using the numerical method. For evaluating the orbit prediction accuracy of IODS, the orbital data predicted for the meteorological satellite NOAA-11 and the stationary satellite INTELSAT-V are intercompared with those tracked at the Central Bureau of Meterology and the Kum-San Satellite Communication Station. And the Perturbations affecting the orbit of these artificial satellites are quantitatively analyzed. The orbital variation and the eclipse phenomina due to the shadow are analyzed for a hypothetical geostationary satellite called KORSAT-1 which is assumed to be located in longitude $110^{circ}E$.

• The Bulletin of The Korean Astronomical Society
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• v.36 no.2
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• pp.97.1-97.1
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• 2011

In this study we have examined the probability of solar proton events (SPEs) and their peak fluxes depending on flare (flux, longitude and impulsive time) and CME parameters (linear speed, longitude, and angular width). For this we used the NOAA SPE list and their associated flare data from 1976 to 2006 and CME data from 1997 to 2006. We find that about 3.5% (1.9% for M-class and 21.3% for X-class) of the flares are associated with SPEs. It is also found that this fraction strongly depends on longitude; for example, the fraction for $30W^{\circ}$ < L < $90W^{\circ}$ is about three times larger than that for $30^{\circ}E$ < L < $90^{\circ}E$. The SPE probability with long duration (${\geq}$ 0.3 hours) is about 2 (X-class flare) to 7 (M-class flare) times larger than that for flares with short duration (< 0.3 hours). In case of halo CMEs with V ${\geq}$ 1500km/s, 36.1% are associated with SPEs but in case of partial halo CME ($120^{\circ}$ ${\leq}$ AW < $360^{\circ}$) with 400 km/s ${\leq}$ V < 1000 km/s, only 0.9% are associated with SPEs. The relationships between X-ray flare peak flux and SPE peak flux are strongly dependent on longitude and impulsive time. The relationships between CME speed and SPE peak flux depend on longitude as well as direction parameter. From this study, we suggest a new SPE forecast method with three-steps: (1) SPE occurrence probability prediction according to the probability tables depending on flare and CME parameters, (2) SPE flux prediction from the relationship between SPE flux and flare (or CME) parameters, and (3) SPE peak time.

• Journal of the Korean Society of Industry Convergence
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• v.7 no.1
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• pp.97-105
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• 2004

The Vapor-liquid equilibrium data for the binary system of 2-methyl-2-propanol-2-butanone are measured at subatmospheric pressure of 100, 200, 300, 400, 500, 600, 700 and 760 torr. This study shows that the relations between logarithmic values of relative valatility(log ${\alpha}$)and liquid phase composition(${\chi}$) in the above binary systems are expressed as a linear function. When the linear relationships of between logarithmic values of relative volatilities and liquid phase compositions in the binary systems of various pressure intersect at a point, this empirical equation can be applied to the systems of this kind. From these relations the vapor-liquid equilibrium data are estimated and compared with the measured values to be in a good agreement with in accuracy ${\pm}0.0021$ for the various pressure.

• International conference on construction engineering and project management
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• 2007.03a
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• pp.721-728
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• 2007

The prediction of quality characteristics during the design phase of a construction project was fragmented, because no particular method exists. One of the most important key responses is the total displacements (horizontal and vertical). A brainstorming session produces the quality parameters i.e. the control factors which here are identified as: the steel joint, the pile's length, the excavation depth and angle, the distance between the piles, the anchor stretch and length to name just some of the most engaging in the design. The purpose of this study is to optimise these parameters to minimize the total displacements following a methodology based on Taguchi method. For this reason, a 2-level, L₈ orthogonal array has been employed to organize the experimentation. Data is obtained from a real-life excavation project designed on the Plaxis v.8 CAE package. Taguchi analysis is performed in the statistical package Minitab.

• Journal of the Korean Chemical Society
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• v.60 no.4
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• pp.225-234
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• 2016

The activity of 34 sulfonamide derivatives has been estimated by means of multiple linear regression (MLR), artificial neural network (ANN), simulated annealing (SA) and genetic algorithm (GA) techniques. These models were also utilized to select the most efficient subsets of descriptors in a cross-validation procedure for non-linear -log (IC50) prediction. The results obtained using GA-ANN were compared with MLR-MLR, MLR-ANN, SA-ANN and GA-ANN approaches. A high predictive ability was observed for the MLR-MLR, MLR-ANN, SA-ANN and MLR-GA models, with root mean sum square errors (RMSE) of 0.3958, 0.1006, 0.0359, 0.0326 and 0.0282 in gas phase and 0.2871, 0.0475, 0.0268, 0.0376 and 0.0097 in solvent, respectively (N=34). The results obtained using the GA-ANN method indicated that the activity of derivatives of sulfonamides depends on different parameters including DP03, BID, AAC, RDF035v, JGI9, TIE, R7e+, BELM6 descriptors in gas phase and Mor 32u, ESpm03d, RDF070v, ATS8m, MATS2e and R4p, L1u and R3m in solvent. In conclusion, the comparison of the quality of the ANN with different MLR models showed that ANN has a better predictive ability.

• Journal of Korean Society of Environmental Engineers
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• v.30 no.9
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• pp.955-960
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• 2008

We investigated and estimated at the characteristics of decomposition and mineralization of benomyl using a design of experiment(DOE) based on the general factorial design in an E-beam process, and also the main factors(variables) with benomyl concentration(X$_1$) and E-beam irradiation(X$_2$) which consisted of 5 levels in each factor was set up to estimate the prediction model and the optimization conditions. At frist, the benomyl in all treatment combinations except 17 and 18 trials was almost degraded and the difference in the decomposition of benomyl in the 3 blocks was not significant(p > 0.05, one-way ANOVA). However, the % of benomyl mineralization was 46%(block 1), 36.7%(block 2) and 22%(block 3) and showed the significant difference of the % that between each block(p < 0.05). The linear regression equations of benomyl mineralization in each block were also estimated as followed; block 1(Y$_1$ = 0.024X$_1$ + 34.1(R$^2$ = 0.929)), block 2(Y$_2$ = 0.026X$_2$ + 23.1(R$^2$ = 0.976)) and block 3(Y$_3$ = 0.034X$_3$ + 6.2(R$^2$ = 0.98)). The normality of benomyl mineralization obtained from Anderson-Darling test in all treatment conditions was satisfied(p > 0.05). The results of prediction model and optimization point using the canonical analysis in order to obtain the optimal operation conditions were Y = 39.96 - 9.36X$_1$ + 0.03X$_2$ - 10.67X$_1{^2}$ - 0.001X$_2{^2}$ + 0.011X$_1$X$_2$(R$^2$ = 96.3%, Adjusted R$^2$ = 94.8%) and 57.3% at 0.55 mg/L and 950 Gy, respectively. A Microtox test using V. fischeri showed that the toxicity, expressed as the inhibition(%), was reduced almost completely after an E-beam irradiation, whereas the inhibition(%) for 0.5 mg/L, 1 mg/L and 1.5 mg/L was 10.25%, 20.14% and 26.2% in the initial reactions in the absence of an E-beam illumination.

• Applied Chemistry for Engineering
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• v.10 no.5
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• pp.677-681
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• 1999

For the binary cyclohexanol-cyclohexanone system the vapor-liquid equilibrium data, which are the necessary ones for the design of the distillation columns in separation process of volatile liquid-mixtures, are measured at subatmospheric pressure of 150, 300 and 500 mmHg. An empirical relation between logarithmic values of relative volatility(log $\alpha$) and liquid phase composition(x), which predicts the vapor-liquid equilibrium data, is obtained from above measured data of 150, 300 and 500 mmHg and the published ones of 30, 100, 200, 395 and 750 mmHg. The predicted data are compared with the measured and published ones to be in good agreement.

• Mass Spectrometry Letters
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• v.10 no.3
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• pp.93-101
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• 2019

Algorithms and software for predicting tandem mass spectra have been developed in recent years. In this work, we explore how distinct in silico $MS^2$ spectra are predicted for isomers, i.e. compounds having the same formula and similar molecular structures, to differentiate between them. We used the CFM-ID 2.0/3.0 predictor with regard to (a) test compounds, whose experimental mass spectra had been randomly sampled from the MassBank of North America (MoNA) collection, and to (b) the most widespread isomers of test compounds searched in the PubChem database. In the first validation test, in silico mass spectra constitute a reference library, and library searches are performed for test experimental spectra of "unknowns". The searches led to the true positive rate (TPR) of ($46-48{\pm}10$)%. In the second test, in silico and experimental spectra were interchanged and this resulted in a TPR of ($58{\pm}10$)%. There were no significant differences between results obtained with different metrics of spectral similarity and predictor versions. In a comparison of test compounds vs. their isomers, a statistically significant correlation between mass spectral data and structural features was observed. The TPR values obtained should be regarded as reasonable results for predicting tandem mass spectra of related chemical structures.

• Korean Chemical Engineering Research
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• v.55 no.5
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• pp.668-678
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• 2017

Intermolecular interactions were studied for binary mixtures of 2-propanol + cyclohexane, n-hexane, benzene, toluene, o-, m- and p-xylenes by measuring ultrasonic speeds (u) over the entire range of composition at 298.15 K and 308.15 K. From these results the deviation in ultrasonic speed was calculated. These results were fitted to the Redlich-Kister equation to derive the binary coefficients along with standard deviations between the experimental and calculated data. Acoustic parameters such as excess isentropic compressibility ($K_s^E$), intermolecular free length ($L_f$) and available volume ($V_a$) were also derived from ultrasonic speed data and Jacobson's free length theory. The ultrasonic speed data were correlated by Nomoto's relation, Van Dael's mixing relation, impedance dependence relation, and Schaaff's collision factor theory. Van Dael's relation gives the best prediction of u in the binary mixtures containing aliphatic hydrocarbons. The ultrasonic speed data and isentropic compressibility were further analyzed in terms of Jacobson's free length theory.