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Assessment of Image Quality of Dual Energy 256 MDCT Technique Focused on keV Changes for MCA Stroke in Cerebral Angiography : Single Energy CT Standard Reference Mode (뇌혈관 조영 검사 시 중대뇌동맥 뇌졸중에 대한 keV 변화를 중심으로 이중 에너지 256 MDCT 기법의 영상의 질 평가 : 단일에너지 CT 표준방식)

  • Goo, Eun-Hoe
    • Journal of the Korean Society of Radiology
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    • v.13 no.7
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    • pp.961-968
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    • 2019
  • The purpose of this study was to evaluate the usefulness of cerebral angiography in each energy level by using dual energy technique in CT. Methods were performed on 15 DE images and SE images of CT angiography. For the analysis of images, mean value, standard deviation, SNR and CNR value were determined by setting ROI on MCA, brain parenchyma tissue, and back ground. As a result of concurrent visual evaluation with Likert 5 point scale, the clearest MCA image was confirmed at DE 40 keV and SE 120 kVp(p>0.05). The SNR value of the SE image was measured to be similar to the 40 keV energy level of the DE image. The low energy level image of 40 keV and 50 keV was measured with a high SNR and the contrast ratio was higher than that of the high energy image.

Electrical and Mechanical Noise Study of the 765kV Transmission Line (765kV 송전선로의 전기적 및 기계적 소음고찰)

  • Lee,
    • Journal of KSNVE
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    • v.6 no.1
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    • pp.89-95
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    • 1996
  • If the transmission line voltage is greater than 500kV, audible noise (AN) and hum noise (HN) due to corona discharges on the conductor would be an important design factor for the conductor selection of transmission line. Also there is an aeolian noise: wind noise(WN) from the tower and the conductor due to wind. This paper presents the results of a statistical analysis of audible noise, hum noise, aeolian noise of 6-480mm$^{2}$ conductor bundle in KEPRI 765kV Test Transmission Line which was constructed to develop 765kV double circuit AC transmission line for the first time in the world. The result of the analysis shows that 6-480mm$^{2}$ conductor bundle and tower satisfy configuration the audible noise design criterion of 50dB(A).

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Several Factors Affecting Mass Production of Microlepia strigosa (Thunb.) C. Presl Sporophytes (돌토끼고사리 포자체의 대량생산을 위한 몇 가지 요인)

  • Cho, Ju Sung;Lee, Cheol Hee
    • Horticultural Science & Technology
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    • v.35 no.1
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    • pp.46-58
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    • 2017
  • This study was conducted to investigate the optimal conditions for spore germination, prothallus propagation, sporophyte formation and seedling growth in Microlepia strigosa (Thunb.) C. Presl. Spore germination and prothallus development were promoted by low concentrations of Knop medium nutrient solution. The optimal medium for prothallus propagation and antheridium formation was 2X MS medium with 3% sucrose. The activated charcoal content of the medium did not affect prothallus proliferation. Among the various combinations of culture soil (bedding soil, peat moss, perlite and decomposed granite), a mixture of bedding soil, peat moss and decomposed granite at a ratio of 1 : 1 : 1 (v : v : v) had a positive effect on sporophyte formation. The most efficient conditions for promoting the growth of whole plants (sporophyte seedlings) were 50 - cell plug trays filled with a mixture of bedding soil and decomposed granite at a 2 : 1 (v : v) ratio.

Design of Data Communication System using LVTTL (LVTTL을 이용한 데이터 통신시스템 설계)

  • Kim, Soke-Hwan;Hur, Chang-Wu
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.15 no.3
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    • pp.639-644
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    • 2011
  • By the development of the information superhighway, the current data communication system can be exchanged data quickly and precisely between subscribers. In this paper, LVTTL(Low Voltage Transistor Transistor Logic), Using the fundamental one logic at several kinds of used in communication systems, the LVTTL transmission characteristics were measured by according to the change data transfer rate and the transmission line length. Because the transmission line length required on the current system is 30cm, We analysed LVTTL data transfer characteristics according to the transmission line length required on the current system. The amplitude level of LVTTL at 10Mbps is 3V and 50Mbps is 2.2V and 100Mbps is 2V and 125Mbps is 1.5V and 150Mbps is 1.4V. The length of transmission line 30cm was stable state up to 100Mbps data transfer rate.

A 1.8V 2-Gb/s SLVS Transmitter with 4-lane (4-lane을 가지는 1.8V 2-Gb/s SLVS 송신단)

  • Baek, Seung-Wuk;Jang, Young-Chan
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2013.10a
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    • pp.357-360
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    • 2013
  • A 1.8V 2-Gb/s scalable low voltage signaling (SLVS) transmitter (TX) is designed for mobile applications requiring high speed and low power consumption. It consists of 4-lane TX for data transmission, 1-lane TX for a source synchronous clocking, and a 8-phase clock generator. The proposed SLVS TX has the scaling voltage swing from 50 mV to 650 mV and supports a high speed (HS) mode and a low power (LP) mode. An output impedance calibration scheme for the SVLS TX is proposed to improve the signal integrity. The proposed SLVS TX is implemented by using a $0.18-{\mu}m$ 1-poly 6-metal CMOS with a 1.8V supply. The simulated data jitter of the implemented SLVS TX is about 8.04 ps at the data rate of 2-Gbps. The area and power consumption of the 1-lane of the proposed SLVS TX are $422{\times}474{\mu}m^2$ and 5.35 mW/Gb/s, respectively.

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Discovery of New Fusion Inhibitor Peptides against SARS-CoV-2 by Targeting the Spike S2 Subunit

  • Kandeel, Mahmoud;Yamamoto, Mizuki;Tani, Hideki;Kobayashi, Ayako;Gohda, Jin;Kawaguchi, Yasushi;Park, Byoung Kwon;Kwon, Hyung-Joo;Inoue, Jun-ichiro;Alkattan, Abdallah
    • Biomolecules & Therapeutics
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    • v.29 no.3
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    • pp.282-289
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    • 2021
  • A novel coronavirus, severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), caused a worldwide pandemic. Our aim in this study is to produce new fusion inhibitors against SARS-CoV-2, which can be the basis for developing new antiviral drugs. The fusion core comprising the heptad repeat domains (HR1 and HR2) of SARS-CoV-2 spike (S) were used to design the peptides. A total of twelve peptides were generated, comprising a short or truncated 24-mer (peptide #1), a long 36-mer peptide (peptide #2), and ten peptide #2 analogs. In contrast to SARS-CoV, SARS-CoV-2 S-mediated cell-cell fusion cannot be inhibited with a minimal length, 24-mer peptide. Peptide #2 demonstrated potent inhibition of SARS-CoV-2 S-mediated cell-cell fusion at 1 µM concentration. Three peptide #2 analogs showed IC50 values in the low micromolar range (4.7-9.8 µM). Peptide #2 inhibited the SARS-CoV-2 pseudovirus assay at IC50=1.49 µM. Given their potent inhibition of viral activity and safety and lack of cytotoxicity, these peptides provide an attractive avenue for the development of new prophylactic and therapeutic agents against SARS-CoV-2.

The Analysis of Retention Characteristic according to Remnant Polarization(Pr) and Saturated Polarization(Ps) in 3D NAND Flash Memory (3D NAND Flash Memory의 Remnant Polarization(Pr)과 Saturated Polarization(Ps)에 따른 Retention 특성 분석)

  • Lee, Jaewoo;Kang, Myounggon
    • Journal of IKEEE
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    • v.26 no.2
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    • pp.329-332
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    • 2022
  • In this paper, retention characteristics of lateral charge migration according to parameters of 3D NAND flash memory to which ferroelectric (HfO2) structure is applied and ∆Vth were analyzed. The larger the Ps, the greater maximum polarization possible in ferroelectric during Programming. Therefore, the initial Vth increases by about 1.04V difference at Ps 70µC/cm2 than at Ps 25µC/cm2. Also, electrons trapped after the Program operation causes lateral charge migration over time. Since ferroelectric maintains polarization without applying voltage to the gate after Programming, regardless of Ps value, polarization increases as Pr increases and the ∆Vth due to lateral charge migration becomes smaller by about 1.54V difference at Pr 50µC/cm2 than Pr 5µC/cm2.

Analysis of Insulation Breakdown Cause in 13.8 kV XLPE Cable (13.8 kV XLPE 케이블의 절연파괴 원인 분석)

  • Kim, Hee-Dong;Park, Yong-Hun;Park, Jae-Hyun;Kwon, Jae-Ho;Park, Deok-Hyun
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.1173-1174
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    • 2015
  • 내연 발전기(50 MW, 13.8 kV) 출력단자에서 차단기까지 연결된 13.8 kV XLPE(cross-linked polyethylene) 케이블에서 운전중에 절연파괴로 인해 지락이 발생하였다. XLPE 케이블의 건전성을 확인하기 위해 절연저항과 절연진단 시험을 수행하였다. 교류전압을 1~10 kV까지 증가하면서 XLPE 케이블의 유전정접 측정결과 A상과 C상은 0.1%로 일정하게 측정되었다. 반면에 B상의 유전정접은 1 kV에서 0.54%, 2 kV에서 0.68%, 3 kV에서 0.82%, 4 kV에서 1.12%로 증가하였다. 그리고 교류전압을 약 4.3 kV 인가 중에 진단장비가 차단되었다.

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Regulatory Action of $\beta-adrenergic$ Agonist and 8-bromocyclic AMP on Calcium Currents in the Unfertilized Mouse Eggs

  • Haan, Jae-Hee;Cheong, Seung-Jin;Kim, Yang-Mi;Park, Choon-Ok;Hong, Seong-Geun
    • The Korean Journal of Physiology
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    • v.27 no.2
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    • pp.175-183
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    • 1993
  • There are many report suggesting that influx and intracellular calcium concentration $([Ca^{2+}]_i)$ are related to cell signalling in various cells. However, it has not been reported that calcium channel activation is affected by the substances involved in signal transduction pathways in the mouse eggs. In this study, the effects of isoprenaline (ISP) and cyclic AMP on calcium influx through calcium channels were investigated to show their relationship with the signal transduction process in unfertilized mouse eggs. Using whole cell voltage clamp techniques, calcium currents, elicited by the depolarizing pulses of 300 ms duration (from -50 mV to 50 mV in 10 mV increments) from a holding potential of -80 mV, were recorded. The current-voltage (I-V) relation of calcium currents was shown to be bell-shaped; the current began to activate at -50 mV and reached its maximum $(-1.33{\pm}0.16\;nA:\;mean{\pm}S.E.,\;n=7)$ at -10 mV, then decayed at around 50 mV. Calcium currents were fully activated within $7\;ms{\sim}20\;ms$ and completely inactivated 200 ms after onset of the step pulse. ISP within the concentration ranges of $10^{-8}\;M{\sim}10^{-4}\;M$ dose-dependently increased the amplitude calcium current. The permeable cyclic AMP analogue,8-bromocyclic AMP, also increased its maximal amplitude by 46ft at $10^{-5}\;M$, while protein kinase inhibitor (PKI), which is known to inhibit 0.02 phosphorylating units of cyclic AMP-dependent protein kinase (PKA) per microgram decreased calcium currents. Currents recorded in the presence of PKI were resistant to increase by the application of $10^{-5}\;M$. Also, PKI inhibited the calcium current increase elicited by ISP treatment. These results suggest that $\beta-adrenergic$ regulation of the calcium channel is mediated by the cAMP-dependent protein kinase. This signal transduction pathway might play a role in regulating $[Ca^{2+}]_i$, level due to the increase of calcium influx in mouse eggs.

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Effects of the Different Substrates on the Plant Growth and Mineral Contents of Campanula takesimana in Water Culture (배지종류가 추식 수경재배 섬초롱꽃의 생장과 무기성분 함량에 미치는 영향)

  • Cho, Ja-Yong;Kim, Hong-Gi;Yang, Seung-Yul;Son, Dong-Mo;Jang, Hong-Gi;Heo, Buk-Gu;Kim, Chul-Soo
    • Journal of Bio-Environment Control
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    • v.16 no.3
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    • pp.228-232
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    • 2007
  • We have also clarified the effects of the different substrates; (perlite, peatmoss and granular rock-wool) on the plant growth and the mineral contents of Campanula takesimana until 70 days after transplanting. Overall plant growth in terms of plant height, stem diameter, number of leaves, root length, fresh and dry weight of shoot and root were increased in the order of that mixed perlite and peat moss (50 : 50, v/v)>peat moss (100%)>perlite (100%)>granular rock wool (100%). Mineral contents in plants were much more in the order of potassium $(15.38-43.91cmol^+/kg)$, calcium $(5.48-7.78cmol^+/kg)$, magnesium $(4.38-6.55cmol^+/kg)$ and sodium $(1.25-1.69cmol^+/kg)$. The higher mineral contents of plants were also most made in the mixed substrates of perlite and peat moss (50 : 50, v/v).