• Journal of Ginseng Research
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• v.44 no.2
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• pp.215-221
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• 2020

Background: Panax ginseng has been used for a variety of medical purposes in eastern countries for more than two thousand years. From the extensive experiences accumulated in its long medication use history and the substantial strong evidence in modern research studies, we know that ginseng has various pharmacological activities, such as antitumor, antidiabetic, antioxidant, and cardiovascular system-protective effects. The active chemical constituents of ginseng, ginsenosides, are rich in structural diversity and exhibit a wide range of biological activities. Methods: Ginsenoside constituents from P. ginseng flower buds were isolated and purified by various chromatographic methods, and their structures were identified by spectroscopic analysis and comparison with the reported data. The 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H- tetrazolium bromide method was used to test their cytotoxic effects on three human cancer cell lines. Results: Six ginsenosides, namely 6'-malonyl formyl ginsenoside F₁ (1), 3β-acetoxyl ginsenoside F₁ (2), ginsenoside Rh₂₄ (6), ginsenoside Rh₂₅ (7), 7β-hydroxyl ginsenoside Rd (8) and ginsenoside Rh₂₆ (10) were isolated and elucidated as new compounds, together with four known compounds (3-5 and 9). In addition, the cytotoxicity of these isolated compounds was shown as half inhibitory concentration values, a tentative structure-activity relationship was also discussed based on the results of our bioassay. Conclusion: The study of chemical constituents was useful for the quality control of P. ginseng flower buds. The study on antitumor activities showed that new Compound 1 exhibited moderate cytotoxic activities against HL-60, MGC80-3 and Hep-G2 with half inhibitory concentration values of 16.74, 29.51 and 20.48 μM, respectively.

• Animal cells and systems
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• v.15 no.1
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• pp.37-43
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• 2011

The Korean freshwater crayfish, Cambaroides similis, has recently suffered from range reduction and habitat degradation caused by environmental changes and water pollution. For the conservation and restoration of this species, it is necessary to understand the current population structures of Korean C. similis using estimation of their genetic variation. In this study, eight micro satellite loci were developed and characterized from 49 individuals collected from four locations: one population from Mt. Bukhan (BH) and three populations from Mt. Gwanak (GA) in Seoul, Korea. As a result, the number of alleles per locus ranged from 2 to 12. The observed heterozygosities and expected heterozygosities ranged from 0.000 to 0.833 and from 0.125 to 0.943, respectively, and the former values were significantly lower than the latter ones expected under the Hardy-Weinberg equilibrium. No significant linkage disequilibrium was revealed between any of the locus pairs after Bonferroni correction. From the pairwise Fst results over all samples, higher differentiation between GA-BH population pairs (mean 0.1789) was observed than between GA population pairs (mean 0.0454). This was also supported by Mantel's test showing that the genetic distances of these crayfish populations were significantly correlated with geographic distances. This result may show the regional differentiation caused by restricted gene flow between northern (BH) and southern (GA) populations within Seoul. These micro satellite markers have the potential for use in analyses of the genetic diversity and population structure of C. similis species, with implications for its conservation and management plans.

• Journal of Microbiology
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• v.42 no.2
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• pp.152-155
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• 2004

Pseudomonas sp. K82 has been reported to be an aniline-assimilating soil bacterium. However, this strain can use not only aniline as a sole carbon and energy source, but can also utilize benzoate, p-hydroxybenzoate, and aniline analogues. The strain accomplishes this metabolic diversity by using dif-ferent aerobic pathways. Pseudomonas sp. K82, when cultured in p-hydroxybenzoate, showed extradiol cleavage activity of protocatechuate. In accordance with those findings, our study attempted the puri-fication of protocatechuate 4,5-dioxygenase (PCD 4,5). However the purified PCD 4,5 was found to be very unstable during purification. After Q-sepharose chromatography was performed, the crude enzyme activity was augmented by a factor of approximately 4.7. From the Q-sepharose fraction which exhibited PCD 4,5 activity, two subunits of PCD4,5 (${\alpha}$ subunit and ${\beta}$ subunit) were identified using the N-terminal amino acid sequences of 15 amino acid residues. These subunits were found to have more than 90％ sequence homology with PmdA and PmdB of Comamonas testosteroni. The molecular weight of the native enzyme was estimated to be approximately 54 kDa, suggesting that PCD4,5 exists as a het-erodimer (${\alpha}$$_1$${\beta}$$_1$). PCD 4,5 exhibits stringent substrate specificity for protocatechuate and its optimal activity occurs at pH 9 and 15 $^{\circ}C$. PCR amplification of these two subunits of PCD4,5 revealed that the ${\alpha}$ subunit and ${\beta}$ subunit occurred in tandem. Our results suggest that Pseudomonas sp. K82 induced PCD 4,5 for the purpose of p-hydroxybenzoate degradation.

• Convergence Security Journal
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• v.9 no.4
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• pp.21-27
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• 2009

In the environment of development of network bandwidth and intrusion technology there is limit to the pattern analysis of all massed packets through the existing pattern matching method by the intrusion detection system. To detect the packets efficiently when they are received fragmented, it has been presented the matching method only the pattern of packets consisting with the operation system such as Esnort. Pattern matching performance is improved through the use of NMAP, the basic mechanism od Esnort, by scanning the operation system of the same network system and appling pattern match selectively scanned information and the same operation system as the received packets. However, it can be appeared the case of disregarding the receivied packets depending on the diversity of the kind of operation systems and recognition mistake of operation system of nmap. In this paper, we present and verify the improved intrusion detection system shortening the pattern matching time by the creation of hashy table through the pattern hash of intrusion detection system independently with the users system environment .in the state of flux.

• Journal of the Korea Fashion and Costume Design Association
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• v.10 no.2
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• pp.69-78
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• 2008

The purpose of this study is to develop a plan that adopts a fairly tale motif, which is familiar to children, to traditional Korean costume design factors for the development of practical Korean costume enterprises, which lead the Korean costume industry in its existence. Literary research and previous research methods had been used in this study. After comparing traditional Korean costume factors with practical Korean costume factors through literary research, we examined children's Korean costumes and ordinary children costumes. The results of this study are the following: First, the result of literary research, which used traditional Korean costume as motif of practical Korean costume and adopted model factors that the developed motif had used, shows that the design factors of practical Korean Costumes have changed from traditional to modern, seeking practicability and convenience over appearance. Second, practical Korean costumes are suitable when fairy tale illustration is applied to children with curiosity and warm emotions, and towards children, who spend much time on activity during growth. Third, making use of CAD system, which is different from practical Korean costume based on traditional patterns and single color, and using various pint pattern with many stories for the design of practical Korean costumes, and applying diversity to the market of practical Korean costumes, this study provides new design motif from, which people can feel more familiar to practical Korean costumes.

• Journal of Society of Preventive Korean Medicine
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• v.18 no.3
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• pp.57-67
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• 2014

Objective : This study aimed to compare the patients' satisfactions with local Korean Medicine(KM) clinics and networked KM clinics, and to find out which factors had an effect on it. Method : Six local KM clinics and six networked KM clinics were selected, and patients' questionnaires on the satisfaction with KM clinic use were administered using exit poll method. The questionnaires were developed to measure satisfactions with facility, doctor and staffs, and services. 240 patients completed the questionnaires, and the data were statistically analyzed. Results : There was more diversity in patients' diseases among networked KM clinics users, however, treatments provided were not differentiated clinically between two types of KM clinics. Patients' satisfaction scores for local KM clinics were significantly higher than those for networked KM clinics in the aspects of doctors/staffs (9.35 vs 8.92, p<.01) and services (8.76 vs 8.42, p<.05). 90.0% of local KM clinic users expressed their willingness to recommend the clinics they used to others, while 75.0% of networked KM clinics users did. For both the local and networked clinics, 'KM doctors' kindness', and 'process and waiting time' were statistical factors affecting patients' satisfaction. Conclusion : The patients' satisfactions with general KM clinics were higher than those with networked KM clinics. Networked KM clinics need to develop services to meet the diverse medical demands which were created by them selves.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.2
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• pp.195-203
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• 2018

With the explosion of SNS(social network services) users, the social commerce market has emerged as a new consumer market, and will continue to grow in recent years. Despite the market environment, however, studies are lacking as to the causes of frustration that are hurting social commerce activation. This study is based on the 'Hezbollah' 2 Factor Theory and is a study of social commerce users' satisfaction and frustration factors. For this purpose, social commerce site characteristics and user characteristics were first derived from interviews and literature reviews to confirm their relationship to satisfaction and dissatisfied products. The results showed that the price discount rate, diversity, regional infrastructure, and e-commerce familiarity resulted in the impact on the definition of satisfaction, while the price discount rate, interoperability and innovation resulted in the definition of unsatisfactory goods. It also showed that satisfaction affects the definition of intended use. In particular, the price discount rate was found to be the only factor affecting the definition of unsatisfactory as well as affecting the definition of satisfaction.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.29 no.6
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• pp.1327-1337
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• 2019

With the growth of the IoT market, malware security threats are steadily increasing for devices that use the linux architecture. However, except for the major malware causing serious security damage such as Mirai, there is no related technology or research of security community about linux malware. In addition, the diversity of devices, vendors, and architectures in the IoT environment is further intensifying, and the difficulty in handling linux malware is also increasing. Therefore, in this paper, we propose an analysis system based on ELF which is the main format of linux architecture, and a binary based analysis system considering IoT environment. The ELF-based analysis system can be pre-classified for a large number of malicious codes at a relatively high speed and a relatively low-speed binary-based analysis system can classify all the data that are not preprocessed. These two processes are supposed to complement each other and effectively classify linux-based malware.

• Journal of the Korean Institute of Landscape Architecture
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• v.23 no.3
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• pp.167-176
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• 1995

The purpose of this study is to suggest objective basic data for park management proposal through the quantitative analysis of users' behaviors and satisfaction for the actual conditions of management in Moaksan provincial park. For this, users' behaviors and socio-ecnomic characteristics have been analyzed. Specifically, it attempts to investigate users' anticipation and degree of satisfaction applied Expectancy Theory by Likert scale. And users' satisfaction for the actual conditions of management had been analyzed by using the multiple regression. Results of this study can be summarized as follows ; From the aspect of utilization reality, the male usage was silighty higher than female usage, and the usage rate reality, the male usage was slighty higher than female usage, and the usage rate among the young and students such as university students also appeared slightly higher than the norm. Due to the fact, subject park had been provincial park, bus usage was predominant, and users' visit park 1 or 2 times a year. Generally, the value of users' post occupancy evaluation were higher than those of anticipated, and Use in night and facilities were lower. A sense of the season, dense of forest, beauty of skyline and a perspective view appeared as main explicatory variables having positive effects on the satisfaction level for the landscape. Amount of plant and shade were positive variables on the satisfaction and users' had dissatisfaction with trial damage. According to the multiple regression analysis, the major variables to the satisfaction for the actual condition of vegetation management were diversity, recovery of artificial injury.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.2A
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• pp.147-154
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• 2009

Antenna grouping algorithm is hybrid of beamforming and spatial multiplexing. In antenna grouping system, we partition $N_t$ transmit antennas into $N_r$ groups and use beamforming in a group, spatial multiplexing between groups. We can transmit $N_r$ data streams in the $N_t{\times}N_r$ antenna grouping system. With antenna grouping, we can achieve diversity gain through beamforming, and high spectral efficiency through spatial multiplexing. But if channel is ill-conditioned or there are some correlations between antennas, the performance of antenna grouping is seriously degraded and in that case, beamforming is the best transmit strategy. By selecting the antenna grouping mode when channel is well-conditioned and by selecting the beamforming mode when channel is ill-conditioned, we can prevent serious fluctuation of BER performance caused by varying channel condition and achieve the best BER performance. In this paper, we investigate mode selection algorithm which can select antenna grouping mode or beamforming mode. we also propose a simple mode selection criterion.