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Isolation, Physico-chemical Properties, and Biological Activity of New Thiopeptide Antibiotics, Kimorexins

  • Yeo, Woon-Hyung;Kim, Si-Kwan;Kim, Sang-Seock;Yu, Seung-Hun
    • Journal of Microbiology and Biotechnology
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    • v.4 no.4
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    • pp.349-353
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    • 1994
  • An isolate 90-GT-302, identified as Kitasatosporia kimorexae, was found to produce antibiotics that induce mycelial swelling in Magnaporthe grisea, and Fusarium solani. The strain produced at least 5 antibiotics. Among them, the main active compound designated as kimorexin A was isolated and its physico-chemical properties and biological activities were examined, and as a result was found to be of the thiopeptide antibiotic. A comparison between the properties of kimorexin A and those of the known thiopeptide antibiotics led us to conclude that kimorexin A was a new thiopeptide polythiazolyl antibiotic. Kimorexin A showed a narrow antimicrobial spectrum against very limited genus of phytopathogenic fungi. It prevented host plants from infections of Rhizoctonia solani and absolute parasitic fungi, such as Sphaerotheca fuliginea and Puccinia recondita, almost completely at the treatment concentration of approximately 20 ppm.

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KVN/KaVA AGN WG report - Preparation of KVN/KaVA AGN Key Science

  • Sohn, Bong Won;Kino, Motoki
    • The Bulletin of The Korean Astronomical Society
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    • v.39 no.2
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    • pp.115-115
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    • 2014
  • First, We will briefly introduce early science results of AGN observations with KVN and KaVA. KaVA is the combined array of the Korean VLBI network (KVN) and VLBI Exploration of Radio Astronomy (VERA). These include KaVA monitoring of M87, Sgr A* and a few bright blazars and KVN Search for circular polarized Blazars. Furthermore, we will present our future plan of monitoring observation of Sgr A* and M87 with KaVA and Low Radio Power AGN multi frequency polarization survey with KVN. Because of the largeness of their centralsuper-massive black holes, we select them as top-priority sources of our key science program (KSP). The main science goals of the KaVA KSP are (1) mapping the velocity field of the M87 jet and testing magnetically-driven-jet paradigm, and (2) obtaining tightest constraints on physical properties of radio emitting region in Sgr A. High sensitivity achieved through simultaneous multifrequency phase referencing technique of KVN will allow us to explore Low Radio Power AGN cores which build majority of AGNs and therefore are important for undestanding the evolution of AGNs and of their hosts.

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A Study on the Rural Handicapped Old People House Remodeling to correspond with Physical and Mental Disabilities (신체적ㆍ정신적 장애에 대응한 농촌지역 노인주거의 개조방향에 관한 연구)

  • Kim, Jin-Won;Choi, Jang-Soon;Lee, Seung-Jun;Lee, Gwan-Gu;Yoon, Young-Hwal;Seo, Ok-Ha
    • Journal of the Korean Institute of Rural Architecture
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    • v.10 no.2
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    • pp.17-26
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    • 2008
  • There are many problems for the rural old peoples who to use the rural houses practically with physical and mental disabilities to make use of them because the rural houses have a tendency to look alike the urban houses. Today the rural old peoples are treated distantly by the boundary of national reserved power to make and activate their facilities, the shortness of their economically surplus power and the absence nationally social security system in spite of their physical and mental disabilities. So it is necessary for us to remodel symmetrically their rural houses to fit their physical and mental disabilities to spend comfortable living and to develop structure remodeling programs and space reorganization programs of the rural handicapped old peoples' houses to support independent life to correspond with their physical and mental disabilities.

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Anatomical variation of quadratus plantae in relation with flexor digitorum brevis

  • Punnapa Raviteja;Mrudula Chandrupatla;Ramoju Harshitha;Marni Sameer Chowdary
    • Anatomy and Cell Biology
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    • v.56 no.4
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    • pp.562-565
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    • 2023
  • The muscles of the sole have been traditionally categorized into four layers, but it is more practical to divide them into peripheral and central groups. The peripheral groups include medial and lateral groups. The central plantar muscles are more numerous and divided into superficial and deep layers. During routine dissection in the Department of Anatomy, All India Institute of Medical Sciences Bibinagar, Hyderabad, variations are been observed in the plantar intrinsic muscle in the left foot & right foot of a 53-year-old male cadaver. This is the first cadaveric report of a combination of discrepancies especially the inter-tendinous connection between quadratus plantae and flexor digitorum brevis. Similar observations in the literature were not found by us. It is important to identify and study these dissimilarities of muscles of the sole for surgeons, anatomists, radiologists and orthopaedics as these muscles and tendons are used in foot reconstructive procedures, and for the treatment of some congenital anomalies.

NEW CARDINAL FUNCTIONS RELATED TO ALMOST CLOSED SETS

  • Cho, Myung Hyun;Moon, Mi Ae;Kim, Junhui
    • Honam Mathematical Journal
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    • v.35 no.3
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    • pp.541-550
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    • 2013
  • In this paper, we strengthen the properties of approximation by points (AP) and weak approximation by points (WAP) considered by A. Pultr and A. Tozzi in 1993 to define ${\kappa}$-AP and ${\kappa}$-WAP for an infinite cardinal ${\kappa}$. We also strengthen the properties of radial and pseudoradial to define ${\kappa}$-radial and ${\kappa}$-pseudoradial for an infinite cardinal ${\kappa}$. These allow us to consider new cardinal functions related to almost closed sets; AP-number, WAP-number, radial number, and pseudoradial number. We study their properties and show the relationships between them. We also provide some examples around ${\kappa}$-AP and ${\kappa}$-WAP which are closely connected with ${\kappa}$-radial and ${\kappa}$-pseudoradial.

A Study on the High-Speed GaAs IC Logic Gates (고속 GaAs 집적논리 Gate 회로 연구)

  • 이형재;이대영
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.12 no.3
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    • pp.292-297
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    • 1987
  • High-speed GaAs IC Logic Gates being widely studied and developed in the develped countries were reanalysed and reexamined through SPICE simulations. And, furthermore, the detailed examinations of their characteristics such as operation characteristics and conditions, integration densities, service-ableness, and the limitation of both fabrication and application, give us a clue of the feasibility and application of them in the real integrated circuits. This paper will provide a reasonably good guide to set-up one of goals or future development of high-speed GaAs IC's being led by the goverment recently in our country.

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학교에서의 이산수학과 그 역할에 관한 연구

  • 한길준
    • Journal for History of Mathematics
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    • v.16 no.1
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    • pp.45-62
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    • 2003
  • The goals of a major reform effort are to enable us to educate informed citizens who are better able to function in our increasingly technological society. Discrete mathematics is an exciting and appropriate vehicle for working toward and achieving these goals. it is an excellent tool for improving reasoning and problem solving skills. Discrete mathematics has many practical applications that are useful for solving some of the problems of our society and that are meaningful to our students. Its problems make mathematics come alive for students, and help them see the relevance of mathematics th the real word. To build up the role of Discrete mathematics in the school, this study is to investigate various theories and curricula related to discrete mathematics, and to collect a great deal of valuable material that will help teachers introduce discrete mathematics in their classrooms. In conclusion. mathematics teachers will find the need and importance of why and how discrete mathematics can be introduced into their curricula by this study.

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A Study on the Operation Efficiency for Fisheries Cooperative Offices in the Capital and Surrounding Area (수도권 수산업 협동조합 영업점의 효율성 분석)

  • Jung, Jaeheon
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.36 no.1
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    • pp.17-23
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    • 2013
  • This study analyzed the efficiencies of Korean fisheries cooperative's 97 operation offices in the capital and surrounding area. We used the DEA model for checking the technical and scale efficiencies in the financial business of them. We divided the business into two parts, the productivity (efficiency for increasing deposit and loan) and profitability (efficiency for increasing the profit and reducing the risk from the loan). The results show that the additional profitability increase is very difficult because most of the offices have full technical efficiency for profitability. But additional analysis based on Slack-based Measure (SBM) DEA model shows that Kyung-Gi region can increase the profitability. SBM model analysis also gives us the possibility that customized policy can apply to each offices considering each factors affecting the productivity and profitability.

Analysing Archival Appraisal and Selection Decision : Theoretic Approach (기록 평가선별 결정 분석에 관한 연구)

  • Lee, Seung-Eok
    • The Korean Journal of Archival Studies
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    • no.12
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    • pp.37-80
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    • 2005
  • Archival appraisal has been a significant field and demanding task in thoughts and practice about modern archive, in particular, because of insufficiency of resources for the preservation in comparison with the large scale of recorded information. Appraising records does naturally go with the selecting and acquiring them. In the field of appraisal, however, comprehensive accountability on appraisal is much more important than selection and acquisition. The purpose of this study is the proposition of the theoretic approach to the analysis of the factors concerning the archival appraisal. For this purpose, I would try not the actual practice of the archival appraisal but theoretical categories of archival appraisal decision. The archival Characteristic, Value, and Context will be proposed as theoretical categories for the analysis of archival appraisal decision. Firstly, Characteristic category makes it clear to identify the reliable and authentic records, and then, Value provides us with elucidation about the appraisers' recognition of values. Lastly, Context explains the priority of selection throughout creating, using, interrelationship, and social meaning of archives.

Some aspects of the analyses of glass structures exposed to impact load

  • Grozdanic, Gabrijela;Galic, Mirela;Marovic, Pavao
    • Coupled systems mechanics
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    • v.10 no.6
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    • pp.475-490
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    • 2021
  • With glass becoming a structural material there is a whole new approach for loading and ensuring the safety of construction. Due to its brittle nature, it is necessary to predict all possible problems so that structural integrity would not be endangered. In this paper, different approaches to modelling the glass elements are presented with references to the advantages, disadvantages, and application of each of them. The intention is clear, there is a need to improve and simplify the design guidelines. Given the increasing use of glass in construction it is not practical to produce experimental tests each time when the verification is needed. Today, architecture is bringing us different types of structures and every project presents a new challenge for engineers. A practical and simple approach is crucial for progress and efficiency. In this paper, different approaches to modelling glass are presented with an emphasis on soft body impact.