• Asian Pacific Journal of Cancer Prevention
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• 제15권15호
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• pp.6131-6136
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• 2014

Objective: Epidemiology studies have reported conflicting results between glutathione S-transferase Mu-1 (GSTM1), glutathione S-transferase theta-1 (GSTT1) and glutathione S-transferase pi-1 (GSTP1) and ovarian cancer (OC) susceptibility. In this study, an updated meta-analysis was applied to determine whether the deletion of GSTM1, GSTT1 and GSTP1 has an influence on OC susceptibility. Methods: A published literature search was performed through PubMed, Embase, Cochrane Library, and Science Citation Index Expanded database for articles published in English. Pooled odds ratios (ORs) and 95% confidence intervals (95%CIs) were calculated using random or fixed effects models. Heterogeneity between studies was assessed using the Cochrane Q test and $I^2$ statistics. Sub-group analysis was conducted to explore the sources of heterogeneity. Sensitivity analysis was employed to evaluate the respective influence of each study on the overall estimate. Results: In total, 10 published studies were included in the final analysis. The combined analysis revealed that there was no significant association between GSTM1 null genotype and OC risk (OR=1.01, 95%CI: 0.91-1.12). Additionally, there was no significant association between GSTT1 genetic polymorphisms and OC risk (OR=0.98, 95% CI: 0.85-1.13). Similalry, no significant associations were found concerning the GSTP1 rs1695 locus and OC risk. Meanwhile, subgroup analysis did not show a significant increase in eligible studies with low heterogeneity. However, sensitivity analysis, publication bias and cumulative analysis demonstrated the reliability and stability of the current meta-analysis. Conclusions: These findings suggest that GSTs genetic polymorphisms may not contribute to OC susceptibility. Large epidemiological studies with the combination of GSTM1 null, GSTT1 null and GSTP1 Ile105Val polymorphisms and more specific histological subtypes of OC are needed to prove our findings.

• Asian Pacific Journal of Cancer Prevention
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• 제15권2호
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• pp.847-853
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• 2014

There is a lot of debate on the relationship between vitamin D receptor polymorphisms and risk of breast cancer. Herein, we quantitatively analyzed the published case-control studies on this relationship by meta-analysis, performing a bibliographic search from Pubmed and CNKI up to July 31, 2013. The included case-control studies for Fok1, Bsm1, Taq1, Apa1, Cdx2 and Poly-A were 16, 19, 20, 10, 4, 6, respectively. Crude and adjusted odd ratios and 95% confidence intervals were calculated to present and compare the strength of any associations. The results of combined analyses indicated that Fok1, Bsm1, Apa1, Cdx2 and Poly-A were not significantly associated with the risk of breast cancer. In contrast, the tt genotype of Taq1 was a modest risk factor for breast cancer development (tt vs. TT: OR = 1.21, 95% CI: 1.01-1.44). To further confirm the above results, adjusted effects for the six polymorphisms were pooled based on adjusted ORs reported in the original studies. Adjusted ORs of Fok1, Apa1, Cdx2 and Poly-A were similar to the crude ORs. However, Bsm1 and Taq1 showed inconsistent results. For Bsm1, OR for BB vs. bb was 0.85, 95% CI: 0.74-0.98; for Taq1, OR for tt vs. TT was 1.03, 95% CI: 0.92-1.15, and not associated with risk. Subgroup analyses for crude ORs showed some association between Bsm1, Taq1 and breast cancer in Caucasians only, but for adjusted ORs, no associations were found. This meta-analysis suggests that the roles that Fok1, Apa1, Cdx2 and Poly-A polymorphisms play in breast cancer risk are negligible, with Bsm1 and Taq1 as possible exceptions. To be conservative, we still assumed that they may play a modest role in determining breast cancer risk. Further studies are needed to validate our findings.

• 정보처리학회논문지D
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• 제11D권4호
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• pp.783-798
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• 2004

제한된 무선통신 대역폭 및 불완전한 무선통신 인프라, 이동 단말기의 배터리 용량 등과 같은 이동 컴퓨팅 환경의 고유한 특성으로 인해 이동 단말기에서 실행되는 e-비즈니스 응용은 잦은 접속단절에 직면하게 된다. 또한 고가의 무선통신 비용이나 잦은 무선 통신으로 인해 급격하게 소모되는 이동 단말기 전력을 절약하기 위해 자발적인 접속단절 상태에서 동작하기도 한다. 본 연구에서는 데이터비축을 이용하여 대부분 접속 단절 상태에서 이동 단말기에서 자치적으로 이동 트랜잭션을 처리하면서도 데이터 중복과 네트워크 분할로 인해 발생가능한 일관성 문제를 효율적으로 해결할 수 있는 분할 동기화 이동 트랜잭션 모델을 제안한다. 분할 동기화 이동 트랜잭션 모델은 이동 트랜잭션을 컴포넌트 단위로 분할한 후, 서버에서의 사용 가능성과 충돌 가능성을 고려하여 컴포넌트 트랜잭션들로 동기화 우선순위를 할당하고 우선순위가 높은 컴포넌트 트랜잭션들부터 동기화를 우선 실시하여 부분 결과를 공개한다. 결과적으로 이동 클라이언트에서 변경한 데이터에 대한 서버에서의 가용성을 높이고, 중요도가 낮은 부분은 이동 단말기의 제한된 자원 및 무선 대역폭과 고가의 통신 요금 등을 고려하여 서버에 늦게 반영함으로써 무선 대역폭 및 컴퓨팅 자원의 활용도를 극대화시키는 효과를 기대할 수 있다.

• 한국측량학회지
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• 제39권6호
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• pp.469-476
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• 2021

지하공간통합지도는 지반침하 예방을 목적으로 2015년 4월 구축 기본계획을 수립하고 올해까지 전국 시급 지자체 구축 완료를 앞두고 있다. 지하공간통합지도의 활용을 위해 2018년 9월부터 지하안전영향평가 전문기관 대상의 종이도면 제공, 2019년 5월부터 지하정보 활용시스템을 통한 지자체 담당자 대상의 서비스 등이 이루어지고 있다. 그러나 갱신없이 구축 당시의 정보만으로 활용이 이루어지고 있어 최신성·정확성을 확보하지 못한 상태로 정보의 활용성 및 신뢰성이 떨어지고 있다. 이에 본 연구에서는 지하공간통합지도의 핵심구성요소인 지하구조물(지하철, 지하상가, 지하보도, 지하차도, 지하주차장, 공동구)을 대상으로 「지하안전관리에 관한 특별법」 제42조제2항에 따른 준공도면 제출을 위한 표준 서식을 설계하여 지하공간통합지도 갱신체계 구축의 초석을 다지고자 하였다. 그 결과 3차원 지하구조물 자동갱신을 위한 준공도서 제출 표준을 마련하였으며, 자동가공정보에 대한 위치정확도 검증 결과 직선구간에서는 오차가 발생하지 않았으나 곡선 구간에서는 허용오차 내에서 오차가 발생함을 확인하였다. 표준 서식을 기반으로 자동 갱신된 지하구조물 데이터에 대한 검증을 통해 신뢰성을 확보하고 향후, 지하공간통합지도의 활용성 향상을 도모하고자 한다.

• The Journal of Asian Finance, Economics and Business
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• 제7권12호
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• pp.583-591
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• 2020

Employability has recently become the first target of the national higher education. Its model has been updated to catch the new trend of Industry 4.0. This paper aims at analyzing and ranking the determinants of undergraduate employability, focusing on business and economics majors in Ho Chi Minh City, Vietnam. In-depth interviews with content analysis have been primarily conducted to reach an agreement on a key group of factors: human capital, social capital, and identity. The Stochastic Fractal Search Algorithm (SFSA) is then applied to rank the sub-factors. Human capital is composed of three major elements: attitude, skill, and knowledge. Social capital is approached at both structural and cognitive aspects with three typical types: bonding, bridging, and linking. The analysis has confirmed the change of priority in employability determinants. Human capital is still a driver but the priority of attitude has been confirmed in the contemporary context. Then, social capital with the important order of linking, bridging, and bonding is emphasized. Skill, knowledge, and identity share the least weight in the model. It is noted that identity is newly proposed in the model but a certain role has been found. The findings are crucial for education strategies to enhance university graduate employability.

• 산업경영시스템학회지
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• 제42권4호
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• pp.194-202
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• 2019

Reliability analysis of the components frequently starts with the data that manufacturer provides. If enough failure data are collected from the field operations, the reliability should be recomputed and updated on the basis of the field failure data. However, when the failure time record for a component contains only a few observations, all statistical methodologies are limited. In this case, where the failure records for multiple number of identical components are available, a valid alternative is combining all the data from each component into one data set with enough sample size and utilizing the useful information in the censored data. The ROK Navy has been operating multiple Patrol Killer Guided missiles (PKGs) for several years. The Korea Multi-Function Control Console (KMFCC) is one of key components in PKG combat system. The maintenance record for the KMFCC contains less than ten failure observations and a censored datum. This paper proposes a Bayesian approach with a Dirichlet mixture model to estimate failure time density for KMFCC. Trends test for each component record indicated that null hypothesis, that failure occurrence is renewal process, is not rejected. Since the KMFCCs have been functioning under different operating environment, the failure time distribution may be a composition of a number of unknown distributions, i.e. a mixture distribution, rather than a single distribution. The Dirichlet mixture model was coded as probabilistic programming in Python using PyMC3. Then Markov Chain Monte Carlo (MCMC) sampling technique employed in PyMC3 probabilistically estimated the parameters' posterior distribution through the Dirichlet mixture model. The simulation results revealed that the mixture models provide superior fits to the combined data set over single models.

• 농업과학연구
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• 제46권4호
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• pp.1007-1018
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• 2019

In the present study, according to morphological observations followed by recent circumscriptions, we have classified the Korean taxa of the family Linderniaceae into Scrophulariaceae sensu lato has been considered in several works, though the taxa have remained undefined because identification work was mostly done according to vegetative morphological features, such as the leaf shape, leaf margins, and leaf venation. The taxa of Linderniaceae are mostly considered to be weeds and, for correct identification, it is necessary to clarify their taxonomic characteristics. Morphological studies were carried out using samples collected in the field. Micro-morphological observations of the vegetative and floral parts were also performed using light microscopy (LM) and scanning electron microscopy (SEM). We concluded that important characteristics are reproductive morphologies viz. calyx, stamen structure, capsule shape, calyx ratio with capsule, inflorescence morphology, and seed morphology. As a result, we formulated taxa descriptions and provided a key of the genera of Linderniaceae in Korea. Lindernia crustacea (L.) F. Muell. is transferred to Torenia crustacea (L.) Cham. & Schltdl. Lindernia micrantha D. Don and L. angustifolia (Benth.) Wettstein are a synonym of Vandellia micrantha (D. Don) Eb. Fisch., Schäferh. & Kai Müll. Lindernia attenuata Muhl. and L. dubia var. major (Pursh) Pennell are a synonym of Lindernia dubia (L.). Lindernia verbenifolia (Colsm.) Pennell is a synonym of Bonnaya antipoda Druce. Our study reports the presence of four genera: Bonnaya, Lindernia, Torenia, and Vandellia, comprising six taxa under the family Linderniaceae in Korea.

• Smart Structures and Systems
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• 제26권5호
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• pp.559-573
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• 2020

One of the powerful data management tools is Building Information Modeling (BIM) which operates through obtaining, recalling, sharing, sorting and sorting data and supplying a digital environment of them. Employing SHM, a BIM in monitoring systems, would be an efficient method to address their data management problems and consequently optimize the economic aspects of buildings. The recording of SHM data is an effective way for engineers, facility managers and owners which make the BIM dynamic through the provision of updated information regarding the occurring state and health of different sections of the building. On the other hand, digital transformation is a continuous challenge in construction. In a cloud-based BIM platform, environmental and localization data are integrated which shape the Internet-of-Things (IoT) method. In order to improve work productivity, living comfort, and entertainment, the IoT has been growingly utilized in several products (such as wearables, smart homes). However, investigations confronting the integration of these two technologies (BIM and IoT) remain inadequate and solely focus upon the automatic transmission of sensor information to BIM models. Therefore, in this composition, the use of BIM based on SHM and IOT is reviewed and the economic application is considered.

• Archives of Plastic Surgery
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• 제40권1호
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• pp.52-56
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• 2013

Background Measuring grip and pinch strength is an important part of hand injury evaluation. Currently, there are no standardized values of normal grip and pinch strength among the Korean population, and lack of such data prevents objective evaluation of post-surgical recovery in strength. This study was designed to establish the normal values of grip and pinch strength among the healthy Korean population and to identify any dependent variables affecting grip and pinch strength. Methods A cross-sectional study was carried out. The inclusion criterion was being a healthy Korean person without a previous history of hand trauma. The grip strength was measured using a Jamar dynamometer. Pulp and key pinch strength were measured with a hydraulic pinch gauge. Intra-individual and inter-individual variations in these variables were analyzed in a standardized statistical manner. Results There were a total of 336 healthy participants between 13 and 77 years of age. As would be expected in any given population, the mean grip and pinch strength was greater in the right hand than the left. Male participants (137) showed mean strengths greater than female participants (199) when adjusted for age. Among the male participants, anthropometric variables correlated positively with grip strength, but no such correlations were identifiable in female participants in a statistically significant way. Conclusions Objective measurements of hand strength are an important component of hand injury evaluation, and population-specific normative data are essential for clinical and research purposes. This study reports updated normative hand strengths of the South Korean population in the 21st century.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권8호
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• pp.2894-2909
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• 2015

As the number of mobile devices such as smart phones and tablets explodes, the need for new services or applications is also rapidly increasing. Smart class application is one of the emerging applications, in which most of contents are distributed to all members of a class simultaneously. It is highly required to select relay nodes to cover shadow area of radio as well as extend coverage, but existing algorithms in a smart class environment suffer from high control packet overhead and delay for exchanging topology information among all pairs of nodes to select relay nodes. In addition, the relay selection procedure should be repeated in order to adapt to the dynamic topology changes caused by link status changes or device's movement. This paper proposes the learning based relay selection algorithm to overcome aforementioned problems. The key idea is that every node keeps track of its relay quality in a fully distributed manner, where RQI (Relay Quality Indicator) is newly defined to measure both the ability of receiving packets from content source and the ability of successfully relaying them to successors. The RQI of each node is updated whenever it receives or relays broadcast packet, and the node having the higher RQI is selected as a relay node in a distributed and run-time manner. Thus, the proposed algorithm not only removes the overhead for obtaining prior knowledge to select relay nodes, but also provides the adaptability to the dynamic topology changes. The network simulation and experimental results prove that the proposed algorithm provides efficient and reliable content distribution to all members in a smart class as well adaptability against network dynamics.