• 제목/요약/키워드: Unknown Primary

검색결과 289건 처리시간 0.031초

뇌내출혈(ICH)환자의 비수술적 요법으로 치료한 1례(例)에 대한 증례보고(症例報告) (A Case Study about Treatment of soyangin Patient diagnosed as ICH without operated)

  • 박혜선;배영춘;주종천;김형순
    • 사상체질의학회지
    • /
    • 제14권2호
    • /
    • pp.106-114
    • /
    • 2002
  • The etiology of spontaneous intracerebral hematoma is aneurysmal rupture, arteriovenous malfomation, brain rumor, blood dyscrasia, cerebral infaction, cerebra inflammatory vascular disease, hypertension, and unknown causes. And the primary intracerebral hematoma is caused by unknown causes including hypertension. The clinical diagnosis of intracerebral hematoma, size, location, ventricular penetration, and evolution of brain parenchyme by hemorrhage are confirmed by CT scan. The authors have experienced 1 case of spontaneous intracerebral hematoma confirmed by CT scan. We have diagnosed the patient as Soyangin and treated by east integrated therapy. We classified this case as Soyangin-liyoiljung(少陽人裏熱證) and prescribed Yangkyuksanhwatang' Jihwangbaekhotang Hyungbangsabaeksan to the principle of Cheongyangsangsung(淸陽上升). In the result, we had the improvement of the symptoms. This report discribed the process and contents about the way the patient was cured.

  • PDF

초등학교 2·3학년 학생들의 자연수의 덧셈과 뺄셈에 대한 문제해결 능력 분석 (An Analysis on the Elementary 2nd·3rd Students' Problem Solving Ability in Addition and Subtraction Problems with Natural Numbers)

  • 정소윤;이대현
    • 한국수학교육학회지시리즈C:초등수학교육
    • /
    • 제19권2호
    • /
    • pp.127-142
    • /
    • 2016
  • 본 연구에서는 자연수의 덧셈과 뺄셈에서 식으로 된 문제와 의미론적 측면의 유형별 문장제에 대한 학생들의 문제해결 능력을 분석하였다. 이를 위해 초등학교 2학년과 3학년 학생들을 대상으로 본 연구에서 제작한 검사 도구를 활용하여 조사연구를 실시하였다. 연구 결과, 덧셈과 뺄셈식과 문장제 모두에서 결과를 모르는 경우의 정답률이 가장 높았으며, 변화량을 모르는 경우와 처음량을 모르는 경우 순으로 정답률에 차이를 보였다. 덧셈 문장제에서는 결과를 모르는 경우에 합병 상황에서 첨가 상황보다 다소 높은 정답률을 보였으나, 전체적으로는 큰 차이가 없었다. 또 뺄셈 문장제에서는 구잔 유형의 정답률이 구차나 등화 유형의 정답률보다 높았으며, 등화 상황과 구차 상황의 정답률은 큰 차이를 나타내지 않았다.

쇄골상부 림프절의 전이성 종양 - 125예에 대한 병리조직학적 분석 - (Metastatic Tumors in Supraclavicular Lymph Node - Pathologic Analysis of 125 Cases -)

  • 김동석;남혜주;최원희;이태숙
    • Journal of Yeungnam Medical Science
    • /
    • 제8권2호
    • /
    • pp.70-75
    • /
    • 1991
  • 저자들은 최근 8년 3개월동안 영남대학교 의과대학 병리학교실에서 진단된 쇄골상부 림프절의 전이성 종양 125예를 병리조직학적으로 분석하여 다음과 같은 결론을 얻었다. 1) 원발병소는 폐와 위가 각각 54예(43%), 28예(23%)로 가장 많았다. 2) 전이성 쇄골상부 림프절의 조직학적 유형은 선암종이 71예(57%)로 가장 많았고 그외 편평상피암종, 미분화암종, 소세포암종 등은 각각 15예(12%), 11예(9%), 9예(7%)로서 비슷한 비율을 보였다. 3) 조직학적 유형이 선암종일 경우 원발병소는 위가 27예(49%)로 가장 많았고 폐 19예(34%), 담도계 6예(11%) 순이었다. 4) 조직학적 유형이 편평상피암종, 미분화암종, 소세포암종 및 분화도가 불량하여 유형을 판별할 수 없는 암종의 원발병소는 폐가 가장 많았다. 5) 원발병소를 전혀 알 수 없었던 암종 14예의 조직학적 유형은 선암종이 12예(86%)로 가장 많았다.

  • PDF

대중매체 영향에 따른 일부 대학생의 식품안전 지식 조사 (Studies on Food Safety Knowledge of College Students according to Mass-Media Impact)

  • 최병범
    • 한국식품영양학회지
    • /
    • 제24권2호
    • /
    • pp.166-172
    • /
    • 2011
  • This study was conducted to assess food safety knowledge of college students according to mass-media reports. To accomplish this, a survey was conducted to investigate the reliability, of primary mass-media sources on Bovine Spongiform Encephalopathy(BSE) as well as the preferences of college students. The most common sources of media consumed by male and female students were terrestrial television(TV)(60%), the internet(21%), and newspapers(11%) and terrestrial TV(60%), newspapers (18%), and the internet(17%), respectively. The preferences for media of major and non-major students were terrestrial TV(64%), newspapers(17%), and the internet(14%) and terrestrial TV(51%), the internet(22%), and newspapers(19%), respectively. The reliability of media as viewed by male students were as follows: terrestrial TV(53%) and the internet(40%), whereas for female students, these values were terrestrial TV(55%) and the internet(37%). The reliability of media as viewed by major and non-major students was as follows: terrestrial TV(67%) and the internet(28%), and terrestrial TV(44%) and the internet(44%), respectively. In the case of male students, the primary sources for information regarding BSE were terrestrial TV(54%) and the internet(38%), whereas for female students, the primary sources were terrestrial TV(57%) and internet (37%). In the case of major students, the primary sources for information regarding BSE were terrestrial TV(52%) and the Internet(40%), and for non-major students, the internet(47%) and terrestrial TV(39%). Both male and female students were found to have less knowledge regarding prions, SRM(Specified Risk Materials), MM(methionine-methionine) type genes, and cow above 30 months associated with BSE compared to the other factors associated with this disease. The BSE-related knowledge held by major and non-major students was revealed unknown more than the majority of responses. Based on these results, greater effort should be made to provide meaningful information to improve the food-safety knowledge of college students according to mass-media.

일차성 사구체신염의 육미지황탕과 양약 병용요법에 대한 체계적 문헌고찰 및 메타분석 (The Effect of Combination Therapy of Yukmijihwang-tang and Western Medicine on Primary Glomerulonephritis: Systemic Review and Meta-analysis)

  • 허태영;김예슬;김경민
    • 대한한방내과학회지
    • /
    • 제44권1호
    • /
    • pp.12-34
    • /
    • 2023
  • Objective: This study was conducted to evaluate the effectiveness of the combination therapy of Yukmijihwang-tang and Western medicine on primary glomerulonephritis. Methods: We conducted a search using keywords, such as Yukmijihwang-tang and Liuwei Dihuang, in eight databases (CNKI, CiNii, Pubmed, Embase, Cochrane, Science On, OASIS, RISS). There was no limit to the publication period of the papers. A meta-analysis was conducted and classified according to the outcome measurements, such as the total effective rate (TER), serum creatinine (SCr), and blood urea nitrogen (BUN). Data analysis was performed using the RevMan 5.4.1 software, and Cochrane's risk of bias (ROB) was used to assess the quality of the papers. Results: A total of 12 randomized control trials were selected. The meta-analysis showed that the treatment group combining Yumijihwang-tang and Western medicine was more efficient than the control group using Western medicine alone (RR: 1.29, CI: 1.20 to 1.39 p=<0.00001). The treatment group also reduced the BUN (MD: -2.40, CI: -2.90 to -1.89, p<0.00001) and Scr (MD: -33.34, CI: -40.85 to -25.82, P<0.00001) more than the control group. Conclusion: This study suggests that the combination therapy of Yukmijihwang-tang with Western medicine is effective in treating primary glomerulonephritis. However, these findings should be interpreted cautiously due to the unknown or high risk of bias in the included trials.

Periprosthetic Occult Femoral Fracture: An Unknown Side Effect of Press-Fit Fixation in Primary Cementless Total Hip Arthroplasty

  • Ho Hyun Yun;Woo Seung Lee;Young Bin Shin;Tae Hyuck Yoon
    • Hip & pelvis
    • /
    • 제35권2호
    • /
    • pp.88-98
    • /
    • 2023
  • Purpose: The objectives of this study were to examine the prevalence and risk factors for development of periprosthetic occult femoral fractures during primary cementless total hip arthroplasty (THA) and to assess the clinical consequences of these fractures. Materials and Methods: A total of 199 hips were examined. Periprosthetic occult femoral fractures were defined as fractures not detected intraoperatively and on postoperative radiographs, but only observed on postoperative computed tomography (CT). Clinical, surgical, and radiographic analysis of variables was performed for identification of risk factors for periprosthetic occult femoral fractures. A comparison of stem subsidence, stem alignment, and thigh pain between the occult fracture group and the non-fracture group was also performed. Results: Periprosthetic occult femoral fractures were detected during the operation in 21 (10.6%) of 199 hips. Of eight hips with periprosthetic occult femoral fractures that were detected around the lesser trochanter, concurrent periprosthetic occult femoral fractures located at different levels were detected in six hips (75.0%). Only the female sex showed significant association with an increased risk of periprosthetic occult femoral fractures (odds ratio for males, 0.38; 95% confidence interval, 0.15-1.01; P=0.04). A significant difference in the incidence of thigh pain was observed between the occult fracture group and the non-fracture group (P<0.05). Conclusion: Occurrence of periprosthetic occult femoral fractures is relatively common during primary THA using tapered wedge stems. We recommend CT referral for female patients who report unexplained early postoperative thigh pain or developed periprosthetic intraoperative femoral fractures around the lesser trochanter during primary THA using tapered wedge stems.

다발성 폐종괴 및 기관지 점막으로 전이한 원발불명의 악성 흑색종 1예 (A Case of Unknown Primary Malignant Melanoma with Pulmonary and Endobronchial Metastasis)

  • 민영훈;김성욱;진희종;이태유;송헌호;이근석;이정애;박영이;현인규
    • Tuberculosis and Respiratory Diseases
    • /
    • 제53권2호
    • /
    • pp.196-201
    • /
    • 2002
  • 악성 흑색종은 멜라닌세포에서 발생하는 종양으로 전체 악성 종양의 3%를 차지하고, 피부, 안구, 피부주위점막에서 호발한다. 이들은 주로 피부, 림프절, 폐, 간, 골 등으로 전이되고 폐의 전이는 약 5~15%에서 일어난다. 그러나 기관지 점막으로의 전이는 흔하지 않다. 특히 기관지 및 폐장으로 전이된 원발불명의 악성 흑색종은 아직 보고된 예가 없다. 이에 저자들은 기침과 검은색 객담을 주소로 내원하였던 34세 남자환자에서 굴곡성 기관지 내시경 및 조직검사를 시행하여 vimentin, S-100 protein, HMB-45 염색에 양성을 보이는 양측 폐장 및 기관지점막으로 전이된 악성 흑색종을 경험하였기에 문헌고찰과 함께 보고하는 바이다.

Mucoperiosteal Flap Necrosis after Primary Palatoplasty in Patients with Cleft Palate

  • Rossell-Perry, Percy;Cotrina-Rabanal, Omar;Barrenechea-Tarazona, Luis;Vargas-Chanduvi, Roberto;Paredes-Aponte, Luis;Romero-Narvaez, Carolina
    • Archives of Plastic Surgery
    • /
    • 제44권3호
    • /
    • pp.217-222
    • /
    • 2017
  • Background The prevalence of flap necrosis after palatoplasty in patients with cleft palate. The prevalence of mucoperiosteal flap necrosis after palatoplasty remains unknown, and this complication is rare. This event is highly undesirable for both the patient and the surgeon. We present here a new scale to evaluate the degree of hypoplasia of the palate and identify patients with cleft palate at high risk for the development of this complication. Methods In this case series, a 20-year retrospective analysis (1994-2014) identified patients from our records (medical records and screening day registries) with nonsyndromic cleft palate who underwent operations at 3 centers. All of these patients underwent operations using 2-flap palatoplasty and also underwent a physical examination with photographs and documentation of the presence of palatal flap necrosis after primary palatoplasty. Results Palatal flap necrosis was observed in 4 cases out of 1,174 palatoplasties performed at these centers. The observed prevalence of palatal flap necrosis in these groups was 0.34%. Conclusions The prevalence of flap necrosis can be reduced by careful preoperative planning, and prevention is possible. The scale proposed here may help to prevent this complication; however, further studies are necessary to validate its utility.

흉골에 발생한 연골육종: 수술 치험 1례 (Chondrosarcoma of the Sternum - One Case Report -)

  • 정진용
    • Journal of Chest Surgery
    • /
    • 제24권8호
    • /
    • pp.802-806
    • /
    • 1991
  • Primary neoplasms of the ribs and sternum are rare. Most primary bony chest wall neoplasms are malignant, and chondrosarcoma is the most common malignancy in this location The etiology of chondrosarcoma is unknown. Definitive diagnosis of chondrosarcoma can only be made pathologically. The natural history of chest wall chondrosarcoma is one of slow growth and local recurrence. Most tumors of the sternum require wide resection and reconstruction procedures, with potentially serious postoperative problems. Advances in chest wall reconstruction primarily through refinement in muscle transposition and clarification of the functional anatomy and blood supply of trunk muscles, has resulted in a more aggressive resection of the these tumors . Recently we experienced a case with chondrosarcoma of the sternum. A 56 year-old man was admitted to our hospital due to painless, slowly enlarging mass at the left sternoclavicular junctional area. The chest radiograph strongly suggested an underlying cartilaginous neoplasm owing to the appearance of typical flocculent and curvilinear calcifications within the lesion. On CT of the chest, the tumor exhibited a scalloped or lobulated contour, hypodensity of the nonmineralized component in comparison to adjacent muscle, and characteristic stippled cartilaginous matrix mineralization, also typical for cartilaginous neoplasm. The patient underwent wide resection of the chest wall tumor include with a 2-3cm margin of normal tissue on all sides and the thoracic skeletal defect was reconstructed with polytetrafluoroethylene [Gore-Tex] soft-tissue patch. Soft tissue reconstructive procedure was done with the pectoralis major muscle transposition. The patient had an uneventful postoperative course and discharged without adjuvant treatment such as radiation and chemotherapy.

  • PDF

Odontogenic Ameloblast-Associated Protein (Odam) Plays Crucial Roles in Osteoclast Differentiation via Control of Actin Ring Formation

  • Lee, Hye-Kyung;Park, Joo-Cheol
    • Journal of Korean Dental Science
    • /
    • 제8권2호
    • /
    • pp.74-81
    • /
    • 2015
  • Purpose: In osteoclast differentiation, actin-rich membrane protrusions play a crucial role in cell adhesion. Odontogenic ameloblast-associated protein (Odam) contributes to cell adhesion by inducing actin rearrangement. Odam-mediated RhoA activity may play a significant role in multinucleation of osteoclasts. However, the precise function of Odam in osteoclast cell adhesion and differentiation remains largely unknown. Here, we identify a critical role for Odam in inducing osteoclast adhesion and differentiation. Materials and Methods: The expression of Odam in osteoclasts was evaluated by immunohistochemistry. Primary mouse bone marrow and RAW264.7 cells were used to test the cell adhesion and actin ring formation induced by Odam. Result: Odam was expressed in osteoclasts around alveolar bone. Odam transfection induced actin filament rearrangement and cell adhesion compared with the control or collagen groups. Overexpression of Odam promoted actin stress fiber remodeling and cell adhesion, resulting in increased osteoclast fusion. Conclusion: These results suggest that Odam expression in primary mouse osteoclasts and RAW264.7 cells promotes their adhesion, resulting in the induction of osteoclast differentiation.