• Journal of the Korean Wood Science and Technology
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• v.41 no.2
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• pp.149-157
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• 2013

The octopus type oligo-hydroxypropylene glycol ${\beta}$-D-glucopyranosides were successfully synthesized in this studies: the sterospecific compound of allyl 2, 3, 4, 6-tetra-O-acetyl-${\beta}$-D-glucopyranosides (1) was deacetylated with NaOMe in MeOH lead to allyl-${\beta}$-D-glucopyranoside (2) which was perallylated and followed by hydroboration and subsequent oxidation afforded (3-hydroxy-propyl) 2, 3, 4, 6-tetraO(3-hydroxy-propyl)-${\beta}$-D-glucopyranoside (4). As a result, not only allylpropylene glycol ${\beta}$-D-glucopyranosides (5, 7, and 9) but also hydroxypropylene glycol ${\beta}$-D-glucopyranosides (6, 8, and 10) were synthesized by repeated sequential perallylation followed by hydroboration/oxidation.

• Tuberculosis and Respiratory Diseases
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• v.86 no.3
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• pp.166-175
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• 2023

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. The lower airways contain a rich and diverse microbiome, which may play a significant regulatory role in both health and disease. In COPD, the microbiome becomes perturbed, causing dysbiosis. Increased representation of members in the Proteobacteria phylum and certain members in the Firmicutes phylum has been associated with increased risk of exacerbations and mortality. Therapies such as inhaled corticosteroids and azithromycin may modulate the airway microbiome or its metabolites in patients with COPD. This paper provides an up-to-date overview of the airway microbiome and its importance in the pathophysiology of COPD and as potential therapeutic target in the future.

• Tuberculosis and Respiratory Diseases
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• v.87 no.3
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• pp.252-260
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• 2024

Chronic obstructive pulmonary disease (COPD) affects close to 400 million people worldwide and is the 3rd leading cause of mortality. It is a heterogeneous disorder with multiple endophenotypes, each driven by specific molecular networks and processes. Therapeutic discovery in COPD has lagged behind other disease areas owing to a lack of understanding of its pathobiology and scarcity of biomarkers to guide therapies. Single cell RNA sequencing (scRNA-seq) is a powerful new tool to identify important cellular and molecular networks that play a crucial role in disease pathogenesis. This paper provides an overview of the scRNA-seq technology and its application in COPD and the lessons learned to date from scRNA-seq experiments in COPD.

• International Journal of Precision Engineering and Manufacturing
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• v.7 no.3
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• pp.8-13
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• 2006

Plunge milling process is used for machining hole and is widely used in aerospace, automobile, and die/mold industries. The cutter is fed in the direction of spindle axis which has the highest structural rigidity. The kinematics of plunge milling differs from the traditional turning and milling in aspect of tool engagement and chip generation. This paper proposes the mechanistic cutting force model for plunge milling. Uncut chip thickness is calculated using the present cutter edge position and the previous cutter edge position. Instantaneous cutting force coefficients, which depend only on instantaneous uncut chip thickness, are derived based on the mechanistic approach. The developed cutting force model is verified through comparison of the predicted and the measured cutting forces.

• ALGAE
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• v.17 no.1
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• pp.33-39
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• 2002

Mechanisms of competition between two canopy algae and an understory alga were investigated by a field manipulative experiment using artificial thalli. The study was carried out in the upper intertidal zone at Nudibranch Point in Vancouver Island, British Columbia, Canada, where two fucoids, Fucus gardneri and Pelvetiopsis limitata, and a turf red alga, Mazzaella cornucopiae, were dominant in the algal community. The experiment was designed to test three hypotheses, shading, whiplash, and allelopathy, imposed by potential fucoid effects on M. cornucopiae. Only the shading effect was significant, indicating that adult fucoid thalli reduced. M. cornucopiae biomass underneath the fucoids. Results indicated that reversal of competitive dominance existed between F. gardneri and M. cornucopiae depending on the life history stage of the competitors. By including the turf alga's effects on the fucoids, the well-balanced and non-hierarchical interaction networks among the major macroalgae support the high likelihood of species coexistence in the community.

• Proceedings of The Korean Society of Health Promotion Conference
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• 2001.09a
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• pp.81-89
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• 2001

Canada has a rich history in the theory and development of the field of health promotion. Over 25 years ago, in 1974, the Canadian government produced the first government policy document that identified health promotion as a national strategy. The document, which came from the national Health Minister, was entitled A New Perspective on the Health of Canadians (Lalonde, 1974).

• Journal of Fisheries and Marine Sciences Education
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• v.24 no.6
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• pp.950-962
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• 2012

인류의 해양에 대한 의존도가 점차 높아지면서 해양과 인류의 관계를 이해하고 이를 통해 해양의 지속가능성을 유지하기 위한 해양교육은 외국뿐만 아니라 국내에서도 더욱 활발하게 진행되어 가는 추세이다. 북미의 경우 해양교육의 증가에 비례하여 해양교육에 대한 연구도 양적으로 급격히 증가하였음은 물론이고 그 방법 또한 매우 다양하게 이루어지고 있다. 연구란 연구자가 가진 패러다임, 존재론, 인식론을 기반으로 이루어지므로 이에 대해 개략적으로 고찰한 뒤 양적, 질적, 혼합 방법론이 지닌 장점과 제한점을 논의한다. 해양교육과 관련된 북미의 연구논문들(1980년~ 2011년)을 대상으로 연구자들이 사용한 다양한 연구방법 및 디자인을 연구사례와 함께 소개하여 한국에서의 해양교육 연구 설계를 위한 참고자료를 제공한다.

• Journal of the Daesoon Academy of Sciences
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• v.16
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• pp.241-263
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• 2003

조선 시대 중기에 한국은 도교의 내단에 흥미가 고조되는 것을 체험했고, 16~17세기 중에 많은 유교 학자들이 받아들인 호흡법과 심신 수련은 이미 초기 중국에서 고안된 심신 수련자의 신체에서 나오는 기의 순환과 양·질을 강화하는 것이었다. 그러나 18~19세기의 한국인들은 이러한 양생법에 대해서 흥미를 잃게 되지만, 20세기의 지난 반세기 동안에 내단을 이채롭게 다시 부흥시킨 것이다. 여러 가지 새로운 조직체들이 단전호흡과 도인체조를 서울과 다른 도시에서 증진 시키고 있다. 국선도가 1970년에 처음으로 시행되었고 이것은 1984년 새로운 내단으로 되기까지 대중들의 호응을 받지 못했다. 그러나 이러한 심신수련이 새 조직인 단(丹)세계에 의해서 멀리 번창되어 나갔으며 이 조직의 지도자인 이 승훈에 의해서 흥미롭게 다시 소생되었다. 단 세계는 한국에서 무려 360개가 넘는 선원이 있으며 수련자들에 의해서 유럽과 북미에서도 선원이 시작되었다. 이것은 근본적으로 중국의 도교 보다는 고조선 시대 단군에 의해서 고안된 것이라고 말한다. 단 세계는 도교적 양생법 수련보다 한국의 전통적인 것에 대한 자부심을 가지고 장려되고 있다.

• Korean Journal of Plant Taxonomy
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• v.51 no.1
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• pp.1-9
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• 2021

Symplocarpus koreanus (Araceae; Orontioideae) from Korea is described as new. Symplocarpus koreanus has long been considered to be conspecific with S. renifolius in Japan, but phylogenetic, morphological, and cytological data indicate its taxonomic distinction. Compared to S. renifolius, S. koreanus has a much smaller spathe and more spherical spadix with fewer, smaller flowers. Previous phylogenetic studies also suggested that S. koreanus is more closely related to nonthermogenic S. nipponicus than to S. renifolius in Japan. Like its nonthermogenic sister species, S. nipponicus, in Korea and Japan, S. koreanus is diploid (2n = 2x = 30), while S. renifolius in Japan is tetraploid (2n = 4x = 60). A detailed species description, geographical distribution, major morphological differences between the species and a dichotomous key to the species in eastern Asia are provided.

• Journal of Microbiology
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• v.43 no.5
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• pp.383-390
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• 2005

The diversity of the denitrifying bacterial populations in Daejeon Sewage Treatment Plant was examined using a culture-dependent approach. Of the three hundred and seventy six bacterial colonies selected randomly from agar plates, thirty-nine strains that showed denitrifying activity were selected and subjected to further analysis. According to the morphological and biochemical properties, the thirty nine isolates were divided into seven groups. This grouping was supported by an unweighted pair group method, using an arithmetic mean (UPGMA) analysis with fatty acid profiles. Restriction pattern analysis of 16S rDNA with four endonucleases (AluI, BstUI, MspI and RsaI) again revealed seven distinct groups, consistent with those defined from the morphological and biochemical properties and fatty acid profiles. Through the phylogenetic analysis using the 16S rDNA partial sequences, the main denitrifying microbial populations were found to be members of the phylum, Proteobacteria; in particular, classes Gammaproteobacteria (Aeromonas, Klebsiella and Enterobacter) and Betaproteobacteria (Acidovorax, Burkholderia and Comamonas), with Firmicutes, represented by Bacillus, also comprised a major group.