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A comparison of the effects of dexamethasone-pharmacopuncture and dexamethasone-oral administration based on traditional Korean medicine theory on anaphylactic reaction in mice

  • Kim, Jaehak;Kang, Doyoung;Kang, Minsu;Kang, Bora;Kang, Eun Byeol;Kang, Jinseok;Go, YaeJin;Ko, Wheehyoung;Kwak, JaeYoung;Ku, Hyunjung;Gwon, Seo Yeon;Gi, Yumi;Kim, Gayeon;Kim, GyeongMuk;Kim, Kyunghoon;Kim, Kyuri;Kim, Dong Hyun;Kim, MinWoo;Kim, Min Chae;Kim, Seongho;Kim, Seyoon;Kim, Shilla;Kim, ShinHyung;Kim, Young-Jun;Kim, JongHyeon
    • CELLMED
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    • v.3 no.3
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    • pp.24.1-24.5
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    • 2013

  • Pharmacopuncture, or herbal acupuncture, is a new form of therapy derived from combinations of two traditional therapeutic methods, herbal medicine and acupuncture therapy. To compare the efficacy between dexamethasone-pharmacopuncture (DP) and dexamethasone-oral administration (DO), the effect of DP was investigated in murine models. Anti-anaphylactic effects of dexamethasone treatments were investigated in compound 48/80-induced systemic anaphylactic reaction, ear swelling response, and passive cutaneous anaphylaxis (PCA). DP treatment significantly inhibited the compound 48/80-induced systemic anaphylactic reaction, ear swelling response, and PCA. The effects between DP and DO were on a similar level. These results indicate that DP can be used as an alternative method for DO in case of emergency.

  • https://doi.org/10.5667/tang.2013.0017 인용 PDF KSCI