Dementia and Neurocognitive Disorders (대한치매학회지)

Korean Dementia Association (대한치매학회)
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Comparing Neurofilament Light Chain Levels in Serum and Plasma

  • Hyuk Sung Kwon (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Hyesun Lee (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Young Seo Kim (Department of Neurology, Hanyang University College of Medicine) ;
  • Hojin Choi (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Kyu-Yong Lee (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Young Joo Lee (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Eun-Hye Lee (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Mina Hwang (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Hyunhee Park (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine) ;
  • Seong-Ho Koh (Department of Neurology, Hanyang University Guri Hospital, Hanyang University College of Medicine)
  • Received : 2023.03.22
  • Accepted : 2023.05.01
  • Published : 2023.07.31
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References

  1. Khalil M, Teunissen CE, Otto M, Piehl F, Sormani MP, Gattringer T, et al. Neurofilaments as biomarkers in neurological disorders. Nat Rev Neurol 2018;14:577-589. https://doi.org/10.1038/s41582-018-0058-z
  2. Park SA, Jang YJ, Kim MK, Lee SM, Moon SY. Promising blood biomarkers for clinical use in Alzheimer's disease: a focused update. J Clin Neurol 2022;18:401-409. https://doi.org/10.3988/jcn.2022.18.4.401
  3. Forgrave LM, Ma M, Best JR, DeMarco ML. The diagnostic performance of neurofilament light chain in CSF and blood for Alzheimer's disease, frontotemporal dementia, and amyotrophic lateral sclerosis: a systematic review and meta-analysis. Alzheimers Dement (Amst) 2019;11:730-743. https://doi.org/10.1016/j.dadm.2019.08.009
  4. Mattsson N, Andreasson U, Zetterberg H, Blennow K; Alzheimer's Disease Neuroimaging Initiative. Association of plasma neurofilament light with neurodegeneration in patients with Alzheimer disease. JAMA Neurol 2017;74:557-566. https://doi.org/10.1001/jamaneurol.2016.6117
  5. Lee EH, Kwon HS, Koh SH, Choi SH, Jin JH, Jeong JH, et al. Serum neurofilament light chain level as a predictor of cognitive stage transition. Alzheimers Res Ther 2022;14:6.
  6. Altmann P, Ponleitner M, Rommer PS, Haslacher H, Mucher P, Leutmezer F, et al. Seven day preanalytical stability of serum and plasma neurofilament light chain. Sci Rep 2021;11:11034.
  7. Hviid CV, Knudsen CS, Parkner T. Reference interval and preanalytical properties of serum neurofilament light chain in Scandinavian adults. Scand J Clin Lab Invest 2020;80:291-295. https://doi.org/10.1080/00365513.2020.1730434
  8. Syed YY, Deeks E. [(18)F]Florbetaben: a review in β-amyloid PET imaging in cognitive impairment. CNS Drugs 2015;29:605-613.
  9. Harp CT, Hendricks R, Fischer SK, Brumm J, Herman AH. Neurofilament light chain (NfL) levels in CSF, serum, and plasma of healthy donors using the Quanterix NfL Advantage KitTM (P1.9-032). Neurology 2019;92:P1.9-032.