• Annals of Coloproctology
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• v.34 no.6
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• pp.312-316
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• 2018

Purpose: Anemia is associated with poor treatment results for a variety of cancers. The effect of low hemoglobin levels on long-term outcomes after the treatment of patients with an anal squamous cell carcinoma (SCC) remains unclear. For that reason, this study aimed to investigate the effect of anemia on treatment outcomes following chemoradiation for an anal SCC. Methods: This was a retrospective study of all patients who underwent curative treatment for an anal SCC between 2009 and 2015 at 2 trusts in the United Kingdom. Data were collated from prospectively collected cancer databases and were cross-checked with operating-room records and records in the hospitals' patient management systems. Results: We identified 103 patients with a median age of 63 years (range, 36-84 years). The median overall survival was 39 months (range, 9-90 months), and the disease-free survival was 36 months (range, 2-90 months). During the follow-up period, 16.5% patients died and 13.6% patients developed recurrence. Twenty-two people were anemic prior to treatment, with a female preponderance (20 of 22). No differences in disease-free survival (P = 0.74) and overall survival (P = 0.12) were noted between patients with anemia and those with normal hemoglobin levels. On regression the analysis, the combination of anemia, the presence of a defunctioning colostomy, lymph-node involvement and higher tumor stage correlated with poor overall survival. Conclusion: In this study, anemia did not influence disease-free survival or overall survival. We suggest that the interaction between anemia and survival is more complex than previously demonstrated and potentially reliant on other coexisting factors.

• Membrane Journal
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• v.4 no.1
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• pp.1-8
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• 1994

There are growing needs to produce relatively high purity(99.0% or higher) oxygen at low cost. For small scale production, both pressure swing adsorption(PSA) and membrane process are competitive and less expensive or more convenient than well known cryogenic fractionation technology. A continuous membrane column(CMC) combined with a PSA oxygen generator can be employed to produce high purity oxygen continuously. The oxygen enriched gas generated by a PSA unit, with a concentration of 93~94%, is fed to the CMC that consism of three modules of poly(imide) hollow fibers. Several experiments were conducted by varying parameters, such as feed flow rate, transmembrane pressure drop, stage cut, and feed location in order to obtain a high oxygen concentration above 99.0%. A two-series unit mode was also employed with CMC operation to optimize the given membrane area.

• Journal of Korean Association for Spatial Structures
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• v.3 no.4 s.10
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• pp.77-84
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• 2003

Tensegrity systems are stable structures which are reticulated spatial structures composed of compressive straight members, struts and cables. But there are some difficulties concerning surface stability, surface formation and construction method. One of the ways to solve this problem reasonably is combination of tesile members and rigid members. This structure is a type of flexible strutural system which is unstable initially because the cable material has little initial rigidity. Therefore tensegrity structure need to be introduced to the Initial stress for the self-equilibrated system having stable state. The rigidification of tensegrity systems is related to selfstress states which can be achieved only when geometrical and mechanical requirements are simultaneously satisfied. In this paper, for the stabilization of tesnsegrity structure it is proposed the modified self-equilibrated equation and the range of the various geometrical parameter about unit system. And we generate the model of double layed single curvature arch using the new squew quadruplex unit system.

• Journal of the Korean Chemical Society
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• v.19 no.5
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• pp.304-316
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• 1975

A formal theory to explain the Stark effect in molecular exciton states is developed using the second-quantization formalism. In this theory not only the Stark effect but also the Davydov effect are explicitly taken into consideration since the observed spectral splitting in the UV spectra for molecular crystals with two or more molecules per unit cell may be the result of combination of the above two effects. Especially for molecular crystals containing two molecules in a unit cell the splitting is shown to be hyperbolically dependent upon the strength of an externally applied, uniform electric field, from which informations regarding the excited state dipole moments of a single molecule may be obtained.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2015.11a
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• pp.53-54
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• 2015

As the result of uniaxial compression strength test on the CLMS mixing BFS and SS with BFS 4000, it required to determine the desired strength through increasing unit quantity of cement in mixing process because of dramatic strength deterioration of strength according to increasing replacing rate. In this study's result, regardless of differences in fine aggregates used, in order to get uniaxial compression strength in the scope exceeding criteria of minimum strength for applying to the field, the most reasonable combination was to mix replacing BFS with fineness of 6000 in 30%. For the CLMS mixing BFS and SS, in order to improve flow ability by securing quantity of minimum unit and to repress bleeding rate with securing uniaxial compress strength considering the field applicability, regardless of differences in fine aggregates used, to mix BFS over 6000 in 30% was most effective.

• Smart Structures and Systems
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• v.20 no.3
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• pp.263-272
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• 2017

This paper presents the time response of a mixed vibration system with the viscous damping and the hysteretic damping. There are two ways to derive the time response of such a vibration system. One is an analytical method, using the contour integral of complex functions to compute the inverse Fourier transforms. The other is an approximate method in which the analytic functions derived by Hilbert transform are expressed in the state space representation, and only the effective eigenvalues are used to efficiently compute the transient response. The unit impulse responses of the two methods are compared and the change in the damping properties which depend on the viscous and hysteretic damping values is investigated. The results showed that the damping properties of a mixed damping vibration system do not present themselves as a linear combination of damping properties.

• KIEAE Journal
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• v.4 no.3
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• pp.45-52
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• 2004

The purpose of this research was to identify the structural characteristics of open housing typologically and systematically. The main method of this study was content analysis and literature review on open housing. This study found that the typological analysis on terminology and the details of the constituents concerning structural patterns in open housing indicated that the main approaches were classified into three criteria such as 'Organization Element', 'Construction Element', and 'Equipment Element'. Organization Element was classified into 'Main Dwelling Unit Area and its Form', 'Room Organization Method', 'Relationship with the Main Dwelling Unit's External Constituents', and 'Combination Method of Support and Infill'. Construction Element was classified into 'Method of Structure' and 'Structural Element Technology'. Equipment Element was classified into 'Method of Using Duct' and 'Wet Zone Method'. The attributes were determined based on these classifications. The results of this study can be used to construct an evaluation tool and further to develop a framework in understanding open housing. Technical research should be conducted on the variables that affect the flexibility of space.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.4
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• pp.1871-1877
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• 2014

Enhancing of radioresponsiveness of tumors by using radiosensitizers is a promising approach to increase the efficacy of radiation therapy. Recently, the ethanolic extract of the medicinal plant, Derris scandens Benth has been identified as a potent radiosensitizer of human colon cancer HT29 cells. However, cell death mechanisms underlying radiosensitization activity of D scandens extract have not been identified. Here, we show that treatment of HT-29 cells with D scandens extract in combination with gamma irradiation synergistically sensitizes HT-29 cells to cell lethality by apoptosis and mitotic catastrophe. Furthermore, the extract was found to decrease Erk1/2 activation. These findings suggest that D scandens extract mediates radiosensitization via at least two distinct modes of cell death and silences pro-survival signaling in HT-29 cells.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 1992.04a
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• pp.127-132
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• 1992

To relize the future intelligent robot the development of a special-purpose processor for a coordinate transformation is evidently challenging task. In this case the complexity of a hardware architecture strongly depends on the adopted algorithm. In this paper we have used an inverse kinemetics algorithm based on incremental unit computation method. This method considers the 3-axis articulated robot as the combination of two types of a 2-axis robot: polar robot and 2-axis planar articulated one. For each robot incremental units in the joint and Cartesian spaces are defined. With this approach the calculation of the inverse Jacobian matrix can be realized through a simple combinational logic gate. Futhermore, the incremental computation of the DDA integrator can be used to solve the direct kinematics. We have also designed a hardware architecture to implement the proposed algorithm. The architecture consists of serveral simple unitsl. The operative unit comprises several basic operators and simple data path with a small bit-length. The hardware architecture is realized byusing the EPLD. For the straight-line motion of the KAIST arm we have obtained maximum end effector's speed of 12.6 m/sec by adopting system clock of 8 MHz.

• Archives of Plastic Surgery
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• v.39 no.3
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• pp.184-189
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• 2012

Keloid disease is a fibroproliferative dermal tumor with an unknown etiology that occurs after a skin injury in genetically susceptible individuals. Increased familial aggregation, a higher prevalence in certain races, parallelism in identical twins, and alteration in gene expression all favor a remarkable genetic contribution to keloid pathology. It seems that the environment triggers the disease in genetically susceptible individuals. Several genes have been implicated in the etiology of keloid disease, but no single gene mutation has thus far been found to be responsible. Therefore, a combination of methods such as association, gene-gene interaction, epigenetics, linkage, gene expression, and protein analysis should be applied to determine keloid etiology.