• ALGAE
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• 제36권4호
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• pp.333-340
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• 2021

Phylotranscriptomics is the study of phylogenetic relationships among taxa based on their DNA sequences derived from transcriptomes. Because of the relatively low cost of transcriptome sequencing compared with genome sequencing and the fact that phylotranscriptomics is almost as reliable as phylogenomics, the phylotranscriptomic analysis has recently emerged as the preferred method for studying evolutionary biology. However, it is challenging to perform transcriptomic and phylogenetic analyses together without programming expertise. This study presents a protocol for phylotranscriptomic analysis to aid marine biologists unfamiliar with UNIX command-line interface and bioinformatics tools. Here, we used transcriptomes to reconstruct a molecular phylogeny of dinoflagellate protists, a diverse and globally abundant group of marine plankton organisms whose large and complex genomic sequences have impeded conventional phylogenic analysis based on genomic data. We hope that our proposed protocol may serve as practical and helpful information for the training and education of novice phycologists.

• Journal of Oral Medicine and Pain
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• 제47권2호
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• pp.107-108
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• 2022

Artificial intelligence (AI) refers to the use of machines to mimic intelligent human behavior. It involves interactions with humans in clinical settings, and augmented intelligence is considered as a cognitive extension of AI. The importance of AI in healthcare and medicine has been emphasized in recent studies. Machine learning models, such as genetic algorithms, artificial neural networks (ANNs), and fuzzy logic, can learn and examine data to execute various functions. Among them, ANN is the most popular model for diagnosis based on image data. AI is rapidly becoming an adjunct to healthcare professionals and is expected to be human-independent in the near future. The introduction of AI to the diagnosis and treatment of oral diseases worldwide remains in the preliminary stage. AI-based or assisted diagnosis and decision-making will increase the accuracy of the diagnosis and render treatment more precise and personalized. Therefore, dental professionals must actively initiate and lead the development of AI, even if they are unfamiliar with it.

• Journal of Chest Surgery
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• 제55권4호
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• pp.319-324
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• 2022

Although organ transplants have become quite common, combined heart-lung transplantation (CHLTx) is unfamiliar at most institutions. While the remarkable rate of development in treatment options, such as drugs and mechanical circulatory support, have reduced the need for CHLTx, it remains the sole treatment option for a subset of patients with end-stage cardiopulmonary failure. For many cardiothoracic surgeons, CHLTx is not technically new or difficult, but it does pose challenges due to its low frequency and relative complexity. Thus, this review aims to describe the CHLTx technique in technical detail using the existing literature.

• Genomics & Informatics
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• 제20권1호
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• pp.13.1-13.4
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• 2022

A major issue in the use of immune checkpoint inhibitors is their lack of efficacy in many patients. Previous studies have reported that the T cell inflamed signature can help predict the response to immunotherapy. Thus, many studies have investigated mechanisms of immunotherapy resistance by defining the tumor microenvironment based on T cell inflamed and non-T cell inflamed subsets. Although methods of calculating T cell inflamed subsets have been developed, valid screening tools for distinguishing T cell inflamed from non-T cell inflamed subsets using gene expression data are still needed, since general researchers who are unfamiliar with the details of the equations can experience difficulties using extant scoring formulas to conduct analyses. Thus, we introduce TcellInflamedDetector, an R package for distinguishing T cell inflamed from non-T cell inflamed samples using cancer gene expression data via bulk RNA sequencing.

• 항공우주의학회지
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• 제30권1호
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• pp.30-33
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• 2020

The Republic of Korea is rapidly entering an aging society. With the aging of society, the overseas travel of the elderly is increasing rapidly. According to the Korea Tourism Organization, the number of overseas tourists aged 61 or older last year exceeded 2.5 million, of which over 80 were over 200,000. Age is no longer a limiting factor for traveling abroad, but traveling to unfamiliar places is certainly a challenge. Old people may experience a variety of problems, so special care should be taken. In particular, the aircraft cabin environment is different from the ground, so elderly travelers with respiratory or heart disease require special attention. In this paper, we want to know the precautions and how to prepare for the safe air travel for the elderly.

• Journal of Information Technology Applications and Management
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• 제28권6호
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• pp.133-143
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• 2021

Unity's Cinemachine, one of the game production technologies, can produce 3D images. However, since Cinemachine is a game production tool, video creators may find it difficult because the work process of Cinemachine is unfamiliar and complicated. However, it is necessary to learn new technologies for the future of video contents that will be advanced in the future. In order to understand Chinemachine as a video producer, I would like to embody the scene of the movie. We are going to produce a storyboard scene for storytelling in Cinemachine. We defined the workflow of Unity Cinemachine while directing the scene by creating a story, and also checked the advantages and cautions. I hope it will be an opportunity to enjoy using Unity Cinemachine, which is constantly evolving.

• Journal of Trauma and Injury
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• 제36권3호
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• pp.290-294
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• 2023

Generally, patients with severe burst fractures, instability, or neurological deficits require surgical treatment. In most cases, circumferential reconstruction is performed. Surgical methods for three-column reconstruction include anterior, lateral, and posterior approaches. In cases involving an anterior or lateral approach, collaboration with general or thoracic surgeons may be necessary because the adjacent anatomical structures are unfamiliar to spinal surgeons. Risks include vascular or lumbar plexus injuries and cage displacement, and in most cases, additional posterior fusion surgery is required. However, the posterior approach is the most common and anatomically familiar approach for surgeons performing spinal surgery. We present a case in which three-column reconstruction was performed using only the posterior approach to treat a patient with a severe lumbar burst fracture.

• 아시아태평양코퍼스연구
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• 제4권2호
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• pp.57-74
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• 2023

Having a firm grasp of technical terms is essential for learners of Japanese for Specific Purposes (JSP). This research aims to analyze Japanese nursing care vocabulary based on objective corpus-based frequency and subjectively rated word familiarity. For this purpose, we constructed a text corpus centered on the National Examination for Certified Care Workers to extract nursing care keywords. The Log-Likelihood Ratio (LLR) was used as the statistical criterion for keyword identification, giving a list of 300 keywords as target words for a further word recognition survey. The survey involved 115 participants of whom 51 were certified care workers (CW group) and 64 were individuals from the general public (GP group). These participants rated the familiarity of the target keywords through crowdsourcing. Given the limited sample size, Bayesian linear mixed models were utilized to determine word familiarity rates. Our study conducted a comparative analysis of word familiarity between the CW group and the GP group, revealing key terms that are crucial for professionals but potentially unfamiliar to the general public. By focusing on these terms, instructors can bridge the knowledge gap more efficiently.

• International Journal of Internet, Broadcasting and Communication
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• 제15권4호
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• pp.100-106
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• 2023

Bundling has become a general promotion strategy in mobile shopping context. Previous research on bundling has mostly focused on bundle frame or price frame. Even though consumers are searching and purchasing the product in mobile channels, little research has investigated the effects of bundling in mobile shopping. The objectives of this study is to examine how different product image of bundle affects consumer's perception and purchase intention differently, and how brand familiarity moderate this influence. A sample of 140 subjects participated in a within-subjects experiment. A bundling composed of two different product image (a single product vs. bundled products) was evaluated by individuals. Brand familiarity (familiar brand vs. unfamiliar brand) were manipulated to test a set of hypotheses. We found that the effectiveness of bundling does not depend on the type of product image and brand familiarity. The findings of our study provide some implications for researchers and marketers. Although there have been studies on the effects of bundle framing on consumer behavior, we suggest new insights regarding bundling based on product image and mobile shopping context.

• Journal of Chest Surgery
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• 제56권6호
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• pp.456-459
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• 2023

Penetrating chest trauma may result in significant intracardiac injury. A traumatic ventricular septal defect is a rare complication that requires surgical management, particularly if heart failure ensues. We report a case of delayed repair of an outlet-type ventricular septal defect and perforation of the aortic and pulmonary valve leaflets following a stab wound. This report highlights diagnostic and surgical considerations and also presents an opportunity to review the conotruncal anatomy, which may be relatively unfamiliar to many adult cardiac surgeons.