• 한국지진공학회논문집
• /
• 제2권1호
• /
• pp.1-10
• /
• 1998

동적 지반-구조물해석과정에는 수많은 불확실성 요소가 내재되어 있다. 이러한 요소는 입력운동의 정의, 지반-구조물시스템의 모델작성, 해석기법 등에 포함된다. 이 논문은 점탄성 층상지반상의 원자로건물의 지진응답에 대한 매개변수해석을 수행한 결과를 제시한 것이다. 많은 매개변수 중에 입력운동의 정의위치, 구조물의 묻힘정도, 상부토층의 두께와 지반의 강성을 선택하여 지진응답에 미치는 영향을 중점적으로 이 연구에서 다루었다. 해석방법은 진동수에 무관한 지반임피던스를 사용하는 부분구조법인 시간영역에서의 모드중첩법이다. 지반-구조물시스템의 모드감쇠값은 각 모드에 대해 변형에너지에 대한 소멸에너지의 비를 구하여 결정되었다. 이 연구결과로부터 부분구조법에 의한 지반-구조물상호작용해석법의 실용적 이용에 참고할 수 있는 지진응답에 미치는 각 파라메터의 민감도가 제시되었다.

• 지능정보연구
• /
• 제22권2호
• /
• pp.1-11
• /
• 2016

Entani and Tanaka(2007)는 불확실한 데이터를 처리하기에 적합한 구간 평가결과를 얻는 새로운 방법을 제시하였다. 무엇보다 그들의 방법은 구간 데이터를 정규화하여 redundant 데이터를 제거하는데 특징이 있다. 더 나가 정규화된 구간데이터를 활용하여 계층분석과정(AHP)에서 최종 구간 우선순위벡터를 도출한다. 이 논문에서는 구간 데이터의 정규화 목적을 달성하기 위해 구간 데이터의 꼭지점을 구하는 쉽고 간편한 휴리스틱 방법을 제시한다. 한편 간단한 검사법을 활용하여 정규화된 데이터를 활용하여 최종 구간 우선순위벡터를 도출하는 방법을 제시하고자 한다. 아울러 Entani and Tanaka(2007)가 제시한 대안간 지배관계 규명 방법을 확장한 지배관계 규명 방법을 제시하고자 한다.

• 한국산학기술학회논문지
• /
• 제20권10호
• /
• pp.486-492
• /
• 2019

함정설계 시에는 초기 운용요구 능력의 불확실성을 고려하여 무수히 많은 대안 중에서 최적의 무장시스템과 플랫폼의 제원을 선정하기 위해서는 시스템적인 접근 방법이 필수적이다. 미 해군은 초기단계 설계 시 최적 설계조합을 시행착오 없이 효율적으로 선정하기 위하여 집합기반 설계를 차기 공기부양정 초기단계 설계에 성공적으로 적용한 바 있다. 집합기반 설계를 적용하기 위해서는 설계조합에 필수적인 모델인 함정통합모델이 필수적이나 아쉽게 현재 실질적인 함정통합모델을 보유하고 있는 국가는 미국, 영국 정도의 극히 일부 국가이며 관련된 기술의 타국으로의 이전도 전혀 허용하지 않고 있다. 본 연구에서는 기존 함정설계 데이터의 벤치마킹을 통해서도 미국을 중심으로 선진화된 최신 설계기법인 집합기반설계가 가능할 수 있도록 유전자알고리즘과 의사결정 방법론인 TOPSIS를 통합한 우리나라의 여건과 역량을 고려한 한국형 집합기반 설계 프로세스를 구축하였으며 현재 연구 및 교육 목적으로 일반에 공개된 DDG-51급 통합함정모델을 이용하여 함정의 무장시스템 초기단계 설계 최적화에 적용하여 제안된 한국형 집합기반설계의 적용 가능성을 검증하였다.

• 산업경영시스템학회지
• /
• 제38권4호
• /
• pp.39-44
• /
• 2015

The VHTR (Very High Temperature gas-cooled nuclear Reactor) has been considered as a major heat source and the most safe generation IV type reactor for mass hydrogen production to prepare for the hydrogen economy era. The VHTR satisfies goals for the GIF (Generation IV International Forum) policy such as sustainablility, economics, reliability and proliferation resistance and physical protection, and safety. As a part of a VHTR economic analysis, we have studied the VHTR construction cost and operation and maintenance cost. However, it is somewhat difficult to expect the ripple effect on the whole industry due to the lack of information about Inter-industries relationship. In many case, the ripple effect are based on experts' knowledge or uncertain qualitative assumptions. As a result, we propose quantitative analysis techniques for ripple effects such as the production inducement effect, added value inducement effect, and employment inducement effect for VHTR 600MWt${\times}$4 modules construction and operation ripple effect based on NOAK (Nth Of A Kind). Because inducement effect values have been published annually, we predict inducement effect's relation function and estimated values including production inducement effect value, added value inducement effect value, and employment inducement effect value using time series and estimated values are verified with published inducement effects' value. This paper presents a new method for the ripple effect and preliminary ripple effect consequence using a time series analysis and inter-industry table. This ripple effect analysis techniques can be applied to effect expectation analysis as well as other type reactor's ripple effect analysis including VHTR for process heat.

• Smart Structures and Systems
• /
• 제19권1호
• /
• pp.39-46
• /
• 2017

Finite element model updating is very effective procedure to determine the uncertainty parameters in structural model and minimize the differences between experimentally and numerically identified dynamic characteristics. This procedure can be practiced with manual and automatic model updating procedures. The manual model updating involves manual changes of geometry and analyses parameters by trial and error, guided by engineering judgement. Besides, the automated updating is performed by constructing a series of loops based on optimization procedures. This paper addresses the ambient vibration based finite element model updating of long span reinforced concrete highway bridges using manual model updating procedure. Birecik Highway Bridge located on the $81^{st}km$ of Şanliurfa-Gaziantep state highway over Firat River in Turkey is selected as a case study. The structural carrier system of the bridge consists of two main parts: Arch and Beam Compartments. In this part of the paper, the arch compartment is investigated. Three dimensional finite element model of the arch compartment of the bridge is constructed using SAP2000 software to determine the dynamic characteristics, numerically. Operational Modal Analysis method is used to extract dynamic characteristics using Enhanced Frequency Domain Decomposition method. Numerically and experimentally identified dynamic characteristics are compared with each other and finite element model of the arch compartment of the bridge is updated manually by changing some uncertain parameters such as section properties, damages, boundary conditions and material properties to reduce the difference between the results. It is demonstrated that the ambient vibration measurements are enough to identify the most significant modes of long span highway bridges. Maximum differences between the natural frequencies are reduced averagely from %49.1 to %0.6 by model updating. Also, a good harmony is found between mode shapes after finite element model updating.

• Clinical and Experimental Pediatrics
• /
• 제64권10호
• /
• pp.531-537
• /
• 2021

Background: Multisystem inflammatory syndrome in children (MIS-C) is a new hyperinflammatory variant that evolved during the coronavirus disease 2019 pandemic. Although the precise pathophysiology of MIS-C is uncertain, it is thought to be due to immune dysregulation occurring after recovery from acute infection. Purpose: Our study aimed to analyze the clinical spectrum, laboratory parameters, imaging characteristics, treatment strategies, and short-term outcomes of children with a diagnosis of MIS-C. Methods: This retrospective and prospective observational study included children less than 16 years of age who were admitted to the pediatric unit of a tertiary care teaching hospital in south India between August 2020 to January 2021 with a diagnosis of MIS-C according to World Health Organization criteria. Results: Twenty-one children were included in the analysis; all had fever with variable combinations of other symptoms. The mean age was 6.9 years; 71.4% were male. Gastrointestinal (80.9%) and cardiovascular (80.9%) systems were the most commonly affected. The majority of children had elevated inflammatory markers, and 16 (76.2%) had echocardiographic abnormalities mimicking Kawasaki disease. Eleven children (52.4%) required intensive care admission, 3 (14.3%) required supplemental oxygen, and 4 (19%) required inotropes. Nine (42.9%) were treated with intravenous immunoglobulin alone, 6 (28.6%) with steroids alone, and 3 (14.3%) with steroids and immunoglobulin. The median hospital stay was 6 days; there were no fatalities. Overweight/obesity, elevated ferritin, and mucocutaneous involvement were significantly associated with a prolonged hospital stay (≥7 days). Sixteen children (76.2%) were followed up till now and all of them had no clinical concerns. Conclusion: MIS-C is an emerging disease with variable presentation. A high index of suspicion is necessary for its early identification and appropriate management. Further research is essential for developing optimal treatment strategies.

• Journal of Genetic Medicine
• /
• 제19권2호
• /
• pp.76-84
• /
• 2022

Purpose: Whole-exome sequencing (WES) has been a useful tool for novel gene discovery of various disease categories, further increasing the diagnostic yield. This study aimed to investigate the clinical utility of WES prospectively in undiagnosed genetic diseases. Materials and Methods: WES tests were performed on 110 patients (age range, 0-28 years) with suspected rare genetic diseases. WES tests were performed at a single reference laboratory and the variants reported were reviewed by clinical geneticists, pediatricians, neurologists, and laboratory physicians. Results: The patients' symptoms varied with abnormalities in the head or neck, including facial dysmorphism, being the most common, identified in 85.4% of patients, followed by abnormalities in the nervous system (83.6%). The average number of systems manifesting phenotypic abnormalities per patient was 3.9±1.7. The age at presentation was 2.1±2.7 years old (range, 0-15 years), and the age at WES testing was 6.7±5.3 years (range, 0-28 years). In total, WES test reported 100 pathogenic/likely pathogenic variants or variants of uncertain significance for 79 out of 110 probands (71.8%). Of the 79 patients with positive or inconclusive calls, 55 (50.0%) patients were determined to have good genotype-phenotype correlations after careful review. Further clinical reassessment and family member testing determined 45 (40.9%) patients to have been identified with a molecular diagnosis. Conclusion: This study showed a 40.9% diagnostic yield for WES test for a heterogeneous patient cohort with suspected rare genetic diseases. WES could be the feasible genetic test modality to overcome the diversity and complexity of rare disease diagnostics.

• 한국시뮬레이션학회논문지
• /
• 제32권3호
• /
• pp.67-74
• /
• 2023

반도체 제조라인(FAB)은 복잡하고 불확실한 운영환경에서 작동하는 대규모의 제조시스템 중 하나로 반도체 설비 운영을 담당하는 엔지니어들은 직관적이고 신속한 공정 스케줄링을 위해 가중치 기반 스케줄링을 널리 사용하고 있다. 가중치 기반 스케줄링에서 가중치 결정은 FAB 성능에 큰 영향을 미치므로 엔지니어들은 가중치 최적화를 위하여 시뮬레이션 기반 의사결정을 활용할 수 있다. 그러나 대규모 시뮬레이션은 많은 실험 비용을 요구하기 때문에 효과적인 의사결정을 위해서 신중한 실험설계가 요구된다. 본 연구에서는 적은 시뮬레이션 실행 내에서 효율적인 스케줄링을 도출하기 위해 세 가지 샘플링 대안(i.e., Optimal latin hypercube sampling(OLHS), Genetic algorithm(GA), and Decision tree based sequential search (DSS))에 대한 비교연구를 수행하였다. 시뮬레이션 실험을 통해 세 가지 대안이 단일 규칙보다 우수한 성능을 보였고, 그중 GA와 DSS가 최적화를 위한 효과적인 대안이 될 수 있음을 확인하였다.

• Korean Journal of Radiology
• /
• 제22권4호
• /
• pp.663-671
• /
• 2021

Objective: To determine the association of macrocalcification and rim calcification with malignancy and to stratify the malignancy risk of thyroid nodules with macrocalcification and rim calcification based on ultrasound (US) patterns. Materials and Methods: The study included a total of 3603 consecutive nodules (≥ 1 cm) with final diagnoses. The associations of macrocalcification and rim calcification with malignancy and malignancy risk of the nodules were assessed overall and in subgroups based on the US patterns of the nodules. The malignancy risk of the thyroid nodules was categorized as high (> 50%), intermediate (upper-intermediate: > 30%, ≤ 50%; lower-intermediate: > 10%, ≤ 30%), and low (≤ 10%). Results: Macrocalcification was independently associated with malignancy in all nodules and solid hypoechoic (SH) nodules (p < 0.001). Rim calcification was not associated with malignancy in all nodules (p = 0.802); however, it was independently associated with malignancy in partially cystic or isoechoic and hyperechoic (PCIH) nodules (p = 0.010). The malignancy risks of nodules with macrocalcification were classified as upper-intermediate and high in SH nodules, and as low and lower-intermediate in PCIH nodules based on suspicious US features. The malignancy risks of nodules with rim calcification were stratified as low and lower-intermediate based on suspicious US features. Conclusion: Macrocalcification increased the malignancy risk in all and SH nodules with or without suspicious US features, with low to high malignancy risks depending on the US patterns. Rim calcification increased the malignancy risk in PCIH nodules, with low and lower-intermediate malignancy risks based on suspicious US features. However, the role of rim calcification in risk stratification of thyroid nodules remains uncertain.

• 농촌계획
• /
• 제30권3호
• /
• pp.9-17
• /
• 2024

Agricultural reservoirs play a crucial role in rural areas, providing essential water resources for agriculture. However, collapses or overfilling of reservoirs can lead to significant damages to both property and lives. Unfortunately, the safety of agricultural reservoirs is often uncertain due to aging infrastructure and lack of comprehensive safety management systems. Additionally, the escalating severity of climate change exacerbates these risks, because of extreme weather events. This study proposes a business model for a flood damage management platform tailored to rural areas to predict downstream flooding caused by agricultural reservoirs and to integrate comprehensive reservoir safety management. It aims to predict more accurate downstream flood damage using improved methods based on previous studies. The proposed business model presents strategies for providing improved downstream flood damage prediction services, and identifies potential customers and service supply strategies for the flood damage management platform. Finally, it presents an economic analysis of the proposed business model and strategies for further revenue generation.