• Title/Summary/Keyword: Ultraviolet-C

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Diphlorethohydroxycarmalol Suppresses Ultraviolet B-Induced Matrix Metalloproteinases via Inhibition of JNK and ERK Signaling in Human Keratinocytes

  • Piao, Mei Jing;Kumara, Madduma Hewage Susara Ruwan;Kim, Ki Cheon;Kang, Kyoung Ah;Kang, Hee Kyoung;Lee, Nam Ho;Hyun, Jin Won
    • Biomolecules & Therapeutics
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    • v.23 no.6
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    • pp.557-563
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    • 2015
  • Skin aging is the most readily observable process involved in human aging. Ultraviolet B (UVB) radiation causes photo-oxidation via generation of reactive oxygen species (ROS), thereby damaging the nucleus and cytoplasm of skin cells and ultimately leading to cell death. Recent studies have shown that high levels of solar UVB irradiation induce the synthesis of matrix metalloproteinases (MMPs) in skin fibroblasts, causing photo-aging and tumor progression. The MMP family is involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes such as arthritis and metastasis. We investigated the effect of diphlorethohydroxycarmalol (DPHC) against damage induced by UVB radiation in human skin keratinocytes. In UVB-irradiated cells, DPHC significantly reduced expression of MMP mRNA and protein, as well as activation of MMPs. Furthermore, DPHC reduced phosphorylation of ERK and JNK, which act upstream of c-Fos and c-Jun, respectively; consequently, DPHC inhibited the expression of c-Fos and c-Jun, which are key components of activator protein-1 (AP-1, up-regulator of MMPs). Additionally, DPHC abolished the DNA-binding activity of AP-1, and thereby prevented AP-1-mediated transcriptional activation. These data demonstrate that by inactivating ERK and JNK, DPHC inhibits induction of MMPs triggered by UVB radiation.

Effect of Heat-Treated Temperature on Surface Crystal Structure and Catalytic Activity of ACF/ZnO Composite under Ultraviolet Irradiation and Ultrasonication

  • Zhang, Kan;Oh, Won-Chun
    • Journal of the Korean Ceramic Society
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    • v.47 no.2
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    • pp.136-141
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    • 2010
  • ACF/ZnO photocatalyst was synthesized by a sol-gel method using activated carbon fiber (ACF) and Zn $(NO_3)_2$ as precursors. Samples were characterized by Brunauer-Emmett-Teller measurements (BET), scanning electron microscope (SEM), X-ray diffraction (XRD), and energy dispersive X-ray (EDX). The XRD results showed that ACF/ZnO composites only included a hexagonal phase by heat-treated temperature at $400^{\circ}C$, $500^{\circ}C$, $600^{\circ}C$, and $700^{\circ}C$. The SEM analysis revealed that the ACF/ZnO composites did not exhibit any morphological changes of the catalyst surface according to the different heat-treated temperatures. The photocatalytic activity of the samples was tested for degradation of methylene blue (MB) solutions under ultraviolet (UV) light and ultrasonication respectively. The results showed that the photocatalytic activity of ACF/ZnO composites heat-treated at $500^{\circ}C$ was higher than other samples, which is ascribed to the fine distribution of ZnO particles on the surface of the ACF. In addition, an ultrasound of low power (50 W) was used as an irradiation source to successfully induce ACF/ZnO composites to perform sonocatalytic degradation of MB. Results indicated that the sonocatalytic method in the presence of ACF/ZnO composites is an advisable choice for the treatments of organic dyes.

raf Proto-oncogene is Involved in Ultraviolet Response in Drosophila

  • Ha, Hye-Yeong;Yu, Mi-Ae
    • Animal cells and systems
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    • v.1 no.4
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    • pp.637-640
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    • 1997
  • Raf-1, a cytoplasmic serine/threonine protein kinase, serves as a central intermediate in many signaling pathways in cell proliferation, differentiation, and development. In this study, we investigated that B-raf, Drosophila homolog of the human c-raf-1, is involved in ultraviolet (UV) responsive events by using hypomorphic mutant $D-raf^{c110}$ and Draf-lacZ transgenic fly. At first, effect of UV damage on the survival of wild-type and $D-raf^{C110}$ strains was examined. In terms of $1/LD_{50}$ value, the relative ratio of UV sensitivities of wild-type versus $D-raf^{C110}$ strain was 1 : 2.2. By using quantitative $\beta$-galactosidase activity analysis, transcriptional activity of the D-raf gene promoter was also examined in UV-irradiated Draf-lacZ transgenic larvae. UV irradiation increased the expression of lacZ reporter gene in Draf-lacZ transgenic fly. However, in $D-raf^{C110}$ strain the transcriptional activity of D-raf gene promoter by UV irradiation was extensively reduced. Results obtained in this study suggest that D-raf plays a role in UV response, leading to better survival of Drosophila to UV damage.

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Alignment Effect of Liquid Crystal on new organics thin film using Ultraviolet Exposure method (UV 조사법을 이용한 새로운 무기박막 표면에 액정 배향 효과)

  • Hwang, Jeoung-Yeon;Kang, Hyung-Ku;Choi, Sung-Ho;Oh, Byeong-Yun;Ham, Moon-Ho;Myoung, Jae-Min;Seo, Dae-Shik
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2005.05a
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    • pp.62-65
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    • 2005
  • We studied the nematic liquid crystal (NLC) alignment capability by the Ultraviolet (UV) alignment method on a-C:H thin-films, and investigated electro-optical performances of the UV aligned twisted nematic (TN)-liquid crystal display (LCD) with the UV exposure on a-C:H thin film surface. A good LC alignment by UV irradiation on a-C:H thin-film surfaces was achieved. Monodomain alignment of the UV aligned TN-LCD can be observed. The good electro-optical (EO) characteristics of the UV aligned TN-LCD was observed with oblique UV exposure on the a-C:H thin film surface for 1min.

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Photocatalytic Degradation of Organic Dyes using CdSe-Mn-C60 Nanocomposites

  • Jiulong Li;Jeong Won Ko;Weon Bae Ko
    • Elastomers and Composites
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    • v.57 no.4
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    • pp.181-187
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    • 2022
  • CdSe-Mn nanocomposites were synthesized using a microwave method with sodium sulfite (Na2SO3), selenium (Se), cadmium sulfate octahydrate (3CdSO4·8H2O), ammonia solution (NH3·H2O), and manganese (II) sulfate monohydrate (MnSO4·H2O). We obtained CdSe-Mn-C60 nanocomposites by calcining CdSe-Mn nanocomposites and fullerene (C60) in an electric furnace at 700 ℃ for 2 h. X-ray diffraction, Raman spectroscopy, and scanning electron microscopy were used to characterize the crystal structures, lattice vibrations, and surface morphologies of the products, respectively. The photocatalytic activities of the CdSe-Mn-C60 nanocomposites were investigated based on the photocatalytic degradations of organic dyes such as BG, MB, MO, and RhB under ultraviolet (UV) irradiation at 254 nm. UV-visible spectrophotometry was used to confirm the degradation process.

Photoisomerization of Polymer by Esterification Reaction between Poly vinyl alcohol and Azobenzene-containing Long Chain Fatty Acids (아조벤젠을 함유한 장쇄지방산과 폴리 비닐알코올간의 에스테르화 반응에 의한 폴리머의 광이성화 현상에 관한 연구)

  • Park, Keun-Ho
    • Journal of the Korean Applied Science and Technology
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    • v.11 no.1
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    • pp.53-60
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    • 1994
  • The Synthesis of azobenzene containing long chain fatty acid and poly vinyl alcohol by esterification reaction($C_{n}-Azo-PVA$) was optimized, starting from P-(P'-hydroxy phenyl azo)-benzoic acid and the product of reaction containing azobenzene chromophores was investigated by ultraviolet spectrophotometery in toluene solvent at room temperature. In addition, UV absorption spectra of Langmmuir Blodggett (LB) film deposited on quartz plate have been measured and the structure of these compounds were ascertained by means of Ultraviolet and FT-IR. Recrystallization of reaction product in the solvent results the experimental yield obtained about 22.27% P-(P'-octadecyloxy phenyl azo)-benzoic acid-poly vinyl alcohol. Long chain azobenzene derivative-poly vinyl alcohols are induced phtoisomerization by u, v, and visible light irradiation. The LB film of azobenzene containing long chain fatty acids($C_{18}-Azo-PVA$) are possible of being applied to functional molecular devices such as photomemory and light switching.

FUV Images and Physical Properties of the OES region

  • Jo, Young-Soo;Min, Kyung-Wook;Seon, Kwang-Il
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.1
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    • pp.69.2-69.2
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    • 2010
  • The far-ultraviolet (FUV) H2 and C IV emission images and spectra of Orion Eridanus Superbubble (OES) is hereby presented. The OES seems to consists of multiple phase through the detection of highly-ionized gas and pervasive neutral hydrogen. The former is traced by hot gas while the latter is traced by cold medium. A spectral image made with H2 fluorescent emission shows that the spatial distribution of hydrogen molecule is well correlated with the dust map. The model spectra was taken from a photodissociation region (PDR) radiation code which find a best suitable parameter such as hydrogen density, gas temperature and incident uv intensity of the radiation field. C IV emission is caused by intermediate temperature ISM about 10^4.5 K~10^6 K. Therefore we could get more clear evidence to reveal the structure of OES. Feature of spectra for the each sub region is also presented and discussed. The data were obtained with the Far-Ultraviolet Imaging Spectrograph (FIMS) and the whole data handling were followed by previous FIMS analysis.

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FUV Images and Physical Properties of the Orion-Eridanus Superbubble region

  • Ko, Young-Soo;Min, Kyoung-Wook;Seon, Kwang-Il
    • The Bulletin of The Korean Astronomical Society
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    • v.35 no.2
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    • pp.71.1-71.1
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    • 2010
  • The far-ultraviolet (FUV) C IV and H2 emission spectra of Orion-Eridanus Superbubble (OES) is hereby presented. The OES seems to consist of multiple phase through the detection of highly-ionized gas and pervasive neutral hydrogen. The former is traced by hot gas while the latter is traced by cold medium. A spectral image made with H2 fluorescent emission shows that the spatial distribution of hydrogen molecule is well correlated with the dust map. The model spectra was taken from a photodissociation region (PDR) radiation code which finds a best suitable parameter such as hydrogen density and intensity of the radiation field. C IV emission is caused by intermediate temperature ISM about 10^5 K. Therefore we could get more clear evidence to reveal the morphology of OES. In this process, the hydrogen density and gas temperature were also estimated. The data were obtained with the Far-Ultraviolet Imaging Spectrograph (FIMS) and the whole data handling were followed by previous FIMS analysis.

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The Photo-reproducibility and Stability of Long Chain Fatty Acid Containing Azobenzene (아조벤젠을 함유한 장쇄 지방산의 광재현성과 안정성에 관한 연구)

  • Par, Keun-Ho;Park, Tae-Gone
    • Journal of the Korean Applied Science and Technology
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    • v.12 no.1
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    • pp.109-114
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    • 1995
  • The Synthesis of long chain fatty acid containing azobenzene and $(C_{n}-Azo)$ was optimized, starting from p-(p'-hydroxy phenyl azo)-benzoic acid and the product of reaction containing azobenzene chromophores was investigated by ultraviolet spectrophotometery in chloroform solvent at the various temperature. In addition, Reversibility and stability of azo compounds have been measured by means of Ultraviolet and the structure of these compound were ascertained by means of FT-IR and NMR. Recrystallization of reaction product in the solvent results the experimental yield obtained about 62.93% p-(p'-octadecyloxy phenyl azo)-benzoic acid. Long chain azobenzene derivatives in chloroform solution are induced photoisomerization by u. v. and visible light irradiation. The solution of long chain fatty acids$(C_{n}-Azo)$ containing azobenzene are possible of being applied to functional molecular devices such as photomemory and light switching.

Extreme Ultraviolet Plasma and its Emission Characteristics Generated from the Plasma Focus in Accordance with Gas Pressure for Biological Applications

  • Kim, Jin Han;Lee, Jin Young;Kim, Sung Hee;Choi, Eun Ha
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.08a
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    • pp.178.2-178.2
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    • 2013
  • Conventional ultraviolets A,B,C are known to be very important factor of killing, changing surface properties of biological cells and materials. It is of great importance to investigate the influence of extreme ultraviolet (EUV) exposure on the biological cell. Here we have studied high density EUV plasma and its emission characteristics, which have been generated by plasma focus device with hypercycloidal pinch (HCP) electrode under various Ar gas pressures ranged from 30~500 mTorr in this experiment. We have also measured the plasma characteristics generated from the HCP plasma focus device such as electron temperature by the Boltzman plot, plasma density by the Stark broading method, discharge images by open-shuttered pin hole camera, and EUV emission signals by using the photodiode AXUV-100 Zr/C.

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