• Journal of The Korean Society of Integrative Medicine
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• v.1 no.3
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• pp.51-62
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• 2013

PURPOSE : This study of 20 healthy male subjects by applying various scapular stabilization exercise to compared Serratus anterior and lower trapezius is change in ultrasound images. METHOD : Thirty healthy subjects voluntarily participated in this study. Ultrasound imaging was recorded from the increasing the activity of Serratus anterior(SA) and Lower trapezius(LT) muscles using Push-up plus, Wall slide, Scapular plane shoulder elevation with resistance exercise. Thickness changes in the Serratus anterior(SA) and lower trapezius(LT) muscles between the relaxed and contracted states in the each exercises. To identify statistical significance, one-way ANOVA with repeated measures was used with the significance level of .05. RESULT : The results of this study were as follows : 1) There were statistically significant difference in thickness changes in the Serratus anterior(SA) and lower trapezius(LT) muscles between the relaxed and contracted states in the each exercises. 2) The Scapular plane shoulder elevation with resistance is more effective to Strengthening in the scapular stabilization muscles than Push up-plus and Wall slide. CONCLUSION : The Scapular plane shoulder elevation with resistance may be used to effectively that patient with various shoulder pain.

• JSTS:Journal of Semiconductor Technology and Science
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• v.14 no.5
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• pp.579-587
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• 2014

This paper presents a variable gain amplifier (VGA) for an analog front-end (AFE) of ultrasound medical imaging. This VGA has a closed-loop topology and shows a 37-dB-linear characteristic with a single-stage amplifier. It consists of an op-amp, a non-binary-weighted capacitor array, and a gain-control block. This non-binary-weighted capacitor array reduces the required number of capacitors and the complexity of the gain-control block. The VGA has been fabricated in a 0.35-mm CMOS process. This work gives the largest gain range of 37 dB per stage, the largest P1 dB of 9.5 dBm at the 3.3-V among the recent VGA circuits available in the literature. The voltage gain is controlled in the range of [-10, 27] dB in a linear-in-dB scale with 16 steps by a 4-bit digital code. The VGA has a bandpass characteristic with a passband of [20 kHz, 8 MHz].

• Journal of Biomedical Engineering Research
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• v.30 no.1
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• pp.79-88
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• 2009

A harmonic quadrature demodulation method to extract the second harmonic component from focused ultrasound signals after a single transmit-receive event is proposed. In the proposed method, the focused ultrasound signal is converted into baseband inphase and quadrature components by multiplying with sine and cosine signals both having twice the center frequency of the transmitted signal and filtering the two modulated signals. The quadrature component is then passed through a Hilbert filter to be added to the inphase component, which leaves only the envelope of the second harmonic component. A novel phase estimation technique is employed in the proposed method to avoid the phase mismatch between the focused signal and the two modulating signals. The proposed method is verified through both theoretical analysis and computer simulations. It is shown that compared to the pulse inversion scheme the proposed method provides almost the same results for stationary targets and significantly improved harmonic to fundamental ratio for moving targets.

• Journal of the Korean Society for Precision Engineering
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• v.28 no.9
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• pp.1103-1109
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• 2011

This research quantitatively confirmed an acoustical anisotropy that exists in a pure titanium plate from the signal of ultrasonic flow detection and suggested a new way to evaluate the acoustical anisotropy by inputting acquired characteristic of ultrasound signal into the neutral network. Using the fact with the suggested method that the characteristic of ultrasound signal is shown differently depending on the pure titanium plate's rolling direction, the neural network was constructed by extracting the characteristic that can decide each direction of $0^{\circ}$, $45^{\circ}$, and $90^{\circ}$ with waveform analysis program. As a result of inputting the characteristic of ultrasound signal acquired from a random rolling direction into the neural network that was built like this, it showed a pattern recognition rate higher than 95% on directions of $0^{\circ}$, $45^{\circ}$, $90^{\circ}$.

• Journal of Pharmaceutical Investigation
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• v.37 no.3
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• pp.131-135
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• 2007

A previous report recently demonstrated that ultrasound-induced hyperthermia (USHT:0.4 watts (W)/$cm^2$ at $41^{\circ}C$) could increase cellular uptake of P-glycoprotein (P-gp) substrates in P-gp expressing cancer cell lines. Since P-gp plays a major role in limiting drug permeability in the multi-drug resistant (MDR) cells, studies were conducted to elucidate the mechanism of USHT on cellular accumulation of P-gp and non-P-gp substrate in MDR cells. To accomplish this aim, we studied the effects of USHT on the accumulation of P-gp substrate, R123 and non-P-gp substrate, antipyrine in MDR cells. We demonstrated that USHT increased permeability of hydrophobic molecules (R123 and $[^{14}C]$-antipyrine). The enhanced permeability is reversible and size-dependent as USHT produces a much larger effect on cellular accumulation of $[^{14}C]$-antipyrine (MW 188) than that of R123 (MW 380.8). These results suggest that USHT could affect MDR cells more sensitive than BBMECs. Also, the present results point to the potential use of USHT to increase cellular uptake of P-gp recognized substrates, mainly anti-cancer agents into cancer cells.

• Journal of radiological science and technology
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• v.39 no.2
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• pp.157-161
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• 2016

The purpose of this study is that in measures the acoustic propagate characteristics and temperature sensitivity of ultrasound tissue mimicking phantom(TM phantom). TM phantom manufacture according to the International Electronical Committee(IEC) guidelines for acoustic propagate characteristics of soft tissue. TM phantom was observed to have the image brightness and the image depth penetration decreases changes convergence which was the subject of ultrasound image characteristics in accordance with an external temperature that the change is reduced in temperature below $22^{\circ}C$. This study provide a basis t o create another TM Phantom and TM Phantom has been determined that it is appropriate for use in more than $22^{\circ}C$.

• Nuclear Engineering and Technology
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• v.42 no.5
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• pp.546-551
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• 2010

The objective of this research is to estimate the crack location and size of a carbon steel pipe by using a laser ultrasound guided wave for the wall thinning evaluation of an elbow. The wall thinning of the carbon steel pipe is one of the most serious problems in nuclear power plants, especially the wall thinning of the carbon steel elbow caused by Flow-Accelerated Corrosion (FAC). Therefore, a non-destructive inspection method of elbow is essential for the nuclear power plants to operate safely. The specimens used in this study were carbon steel elbows, which represented the main elements of real nuclear power plants. The shape of the wall thinning was an oval with a width of 120mm, a length of 80mm, and a depth of 5mm. The L(0,1) and L(0,2) modes variation of the ultrasound guided wave signal is obtained from the response of the laser generation/air-coupled detection ultrasonic hybrid system represent the characteristics of the defect. The trends of these characteristics and signal processing were used to estimate the size and location of wall thinning.

• Transactions of the Society of Information Storage Systems
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• v.9 no.1
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• pp.17-21
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• 2013

Optical coherence tomography (OCT) allows non-invasive, cross-sectional optical imaging of biological tissue with high spatial resolution and acquisition speed. In principle, it is analogous to ultrasound imaging, but uses near-infrared light instead of ultrasound, measuring the time-delay of back-scattered light from within biological tissue. Compared to ultrasound imaging, it exhibits superior spatial resolution (1~10 um) and high sensitivity. Therefore, OCT has been applied to a wide range of applications such as cellular imaging, ophthalmology and cardiology. Here, we describe a novel application of OCT technology in visualizing microneedles embedded in tissue that is developed to deliver drugs into the dermis without the injection mark in the human skin. Detailed three-dimensional structural images of microneedles and biological tissues were obtained. Examining structural modification of microneedles and tissues during insertion process would enable to evaluate performance of various types of microneedles in situ.

• Journal of radiological science and technology
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• v.45 no.4
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• pp.341-346
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• 2022

The color overlay pattern of thyroid shear wave elastography applied in this study distinguishes benign and malignant nodules based on the optimal cut-off value of 74.2 kPa. From august 2021 to september 2021, thyroid ultrasound and elastography were performed on 57 patients with thyroid lesions using an ultrasound device RS85 prestige (Samsung Medison, Korea) and a 2-14 MHz linear transducer. In addition, the results of classification by K-TIRADS for each thyroid nodule and the results of classification by color overlay pattern according to the kPa value of acoustic ultrasound were compared and analyzed. In the color overlay pattern, the results classified as 40 people from dark blue to light blue and 17 people from green to red were similar to the K-TIRADS category results, which were classified as 42 benign and 15 malignant. Between blue and light blue, benign, and between green and red, malignant. If the shear wave elastography method is applied before the fine-needle aspiration cytology of the thyroid nodule is performed, the differential diagnosis of thyroid tissue from benign and malignant can be predicted in advance, and it will help to reduce unnecessary invasive tests.

• Clinical Endoscopy
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• v.57 no.4
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• pp.434-445
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• 2024

Pancreatic cystic lesions (PCLs) have increased in prevalence due to the increased usage and advancements in cross-sectional abdominal imaging. Current diagnostic techniques cannot distinguish between PCLs requiring surgery, close surveillance, or expectant management. This has increased the morbidity and healthcare costs from inappropriately aggressive and conservative management strategies. Endoscopic ultrasound (EUS) needle-based confocal laser endomicroscopy (nCLE) allows for microscopic examination and delineation of the surface epithelium of PCLs. Landmark studies have identified characteristics distinguishing various types of PCLs, confirmed the high diagnostic yield of EUS-nCLE (especially for PCLs with an equivocal diagnosis), and shown that EUS-nCLE helps to change management and reduce healthcare costs. Refining procedure technique and reducing procedure length have improved the safety of EUS-nCLE. The utilization of artificial intelligence and its combination with other EUS-based advanced diagnostic techniques would further improve the results of EUS-based PCL diagnosis. A structured training program and device improvements to allow more complete mapping of the pancreas cyst epithelium will be crucial for the widespread adoption of this promising technology.