• Radiation Oncology Journal
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• 제2권1호
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• pp.21-23
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• 1984

Temperature homogeniety and stationary temperature is the most important thermometric considerations for the clinical use of hyperthermia. A thermal mapping was done in a phantom with thermocouple during hyperthermia which was induced by 1.0MHz,$0.7\~0.8watts/cm^2$ ultrasound and unfocused 2.5cm-diameter transducer. The results were as follows 1. Effective heating range$(42.5^{|circ}C\pm0.5^{\circ}C)$ were obtained 3cm in width and 4cm in depth from surface of phantom and temperature distribution was relatively uniform. 2. There was little heating effect more than 2cm away from transducer axis and more than 5cm in depth. 3. There was hot spots(more than $43^{\circ}C$) in $2.0\pm0.5cm$ depth from transducer along tranducer axis.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1998년도 추계학술대회
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• pp.74-75
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• 1998

The present study employs weak shock theory and bio-heat transfer function to predict the temperature rise due to nonlinear propagation of high amplitude ultrasound. The theory shows that, for the focused ultrasound which is assumed to have an gaussian beam profile and has the focal intensity of $1000W/cm^2$, the temperature rise of liver tissue exposed for 1 second to the energy lost during nonlinear propagation goes up to about $30^{\circ}C$. This indicate that it is necessary to consider the nonlinear propagation induced heating enhancement when setting exposure condition of high intensity focused ultrasound used for cancer thermotherapy.

• 국제학술발표논문집
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• The 9th International Conference on Construction Engineering and Project Management
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• pp.295-303
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• 2022

Residential heating systems in South Korea are largely based on the use of ondol pipelines. Heat is transferred to the floor by passing hot water through a metal or plastic pipe buried within the concrete of the floor. Consequently, it is difficult to clean the inside of these pipes after installation. Over time, foreign substances such as scale accumulate in the pipe when the ondol heating method is used for an extended period. Therefore, in the past, pipes were cleaned by removing foreign substances attached to the inside surfaces of the pipes using high-pressure water or by disassembling the pipes and removing foreign substances with chemical agents. Recently, a method for removing foreign substances through the cavitation effect of ultrasound has been proposed. This idea might lead to the development of new technologies for cleaning pipe interiors. Consequently, this study investigated the use of ultrasound to clean pipes embedded in concrete. In this study, devices that generated ultrasonic waves with various frequencies and directions were prepared. After preparing arbitrarily contaminated pipes, the appropriate frequency, output strength, and output direction for each foreign substance were determined through repeated experiments. The results of this experiment could provide important information for future methods of cleaning the interior of ondol piping systems.

• 한국환경과학회지
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• 제27권9호
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• pp.763-770
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• 2018

Bioremediation in situ is heavily dependent on the oxygenic environment which would privide the dwelling microorganism with sufficient oxygen. The situation could be easily resolved with supply of an Oxygen Releasing Compound (ORC). In this paper we prepared that sort of material out of oyster shell powder (mostly calcium carbonate) that prevails every shore areas of the country. We used two different oxidizing methods in the first step of the whole manufacturing process-conventional heating in a furnace and an ultrasound generator to obtain calcium oxide. Then that calcium oxide was further oxidized into calcium peroxide which may release oxygen under a moisturized condition. The oxygen releasing experiments were run to test the performance of our products, and to determine the gas kinetics during the experiments. Interestingly, calcium peroxide derived from ultrasound treatment was much more energy-effective as ORC than that from furnace heating although the heat derived process was better than that of ultrasound in terms of oxygen content and its releasing rate. We also found that most of the data collected from the gas releasing experiments fairly supported an ordinary $1^{st}$ order kinetics to oxygen concentration, which shaped a sharp discharge of oxygen at the very early moment of each test.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2009년도 제38회 동계학술대회 초록집
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• pp.289-289
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• 2010

정상 세포로부터 암과 같은 종양세포를 제거하는 방법으로 암세포가 사멸되는 임계온도 보다 높게 악성조직에 열을 가하는 방법이 연구되어지고 있다 [1]. 전류가 흐를 수 있는 4개의 전기탐침을 종양조직에 삽입하여 국부적으로 열을 발생시키는 발열요법으로 암을 치료하는 연구가 고려되고 있다. 발열요법은 1960년대에 시작하여 우리나라에서는 1985년 연세 암센터에서 capacitive type의 RF heating 또는 전자파에 의한 국소가온법과 방사선치료와 병용으로 이용되고 있다. 주로 이용되는 방법은 Radio frequency heating, Microwave heating, ultrasound heating을 들수 있다. 라디오주파수는 보통 300 MHz 이하의 주파수를 가리킨다. 본 연구에서는 교류파 대신에 직류전원에 의해 열을 발생하는 경우에 관한 연구이다. 전극에 의해 형성되는 전기장에 대한 방정식은 전도매질에서의 DC 응용모드이고, 조직 내에서의 직류 전류에 의해 발생되는 온도 분포를 모델링하는 bioheat 방정식과 연계된 문제이다. 전기장에 의해 발생되는 열의 근원은 resistive heat 또는 Joule 열이다. 본 연구에서는 교류 전류에 의한 RF heating 대신 단순한 모델의 경우로 직류 전류에 의한 열 발생에 관한 이론적 연구를 수행하였다. 종양 조직 내에 삽입된 전극에 22V를 인가하면 60초 이내에 $80^{\circ}C$까지 급속히 증가 된 후, 서서히 $90^{\circ}C$에 까지 도달한다. 4 개의 전극에 대칭적인 전위가 인가 된 경우 $50^{\circ}C$ 이상의 온도 분포를 암 조직의 모양과 유사하게 분포하게 하여 효과적인 치료를 수행 할 수 있는 조건을 제시한다.

• 한국방사선학회논문지
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• 제9권7호
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• pp.523-528
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• 2015

본 연구에서는 단일 초음파 조사와 두 개의 저강도 초음파의 중첩 조사 시 발생하는 가열 특성을 평가하였다. 비교결과 단일 조사 조건보다 중첩 조사에서 보다 우수한 온열 효과를 보였으며 최대 상승 온도도 120-150% 증가하는 것을 확인할 수 있었다. 초음파 조사에 의한 가열 개시 시간이 중첩 조사에서 짧아지며, 최대 가열 온도까지 소요되는 시간 역시 짧아짐을 확인할 수 있었다. 초음파 조사 강도가 커지면 매질의 표면 손상을 유발하는데, 저강도 중첩조사의 경우 표면의 손상없이 동일한 온도 상승 효과를 확인할 수 있었다. 본 연구의 결과를 통하여 초음파 치료 시 적용 강도를 줄일 수 있을 것으로 생각되었으며, 저강도 초음파를 사용함으로써 보다 안전하고 효율적인 초음파 치료가 가능할 것으로 판단된다.

• 센서학회지
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• 제18권5호
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• pp.377-384
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• 2009

The ultrasonic hyperthermia for oncology has been developed and studied. The HIFU(high intensity focused ultrasound) is the most recent method to treat the tumor by using ultrasound. In this study, an insertion-type transducer for treating a prostate cancer, which can focus the ultrasonic beam mechanically and electrically, was designed and developed. The developed transducer was composed of three arrays, and each array has 32 elements. For the purpose of the mechanical focusing, both side arrays are slanted to the center array by $15^{\circ}$. With this structure, NFL(near field length) was set up as 30 mm. The PZT-4 and two matching layers were used, and the backing layer was excepted to prevent energy losses. The acoustic field analysis and the heating test were performed to evaluate the performance of developed transducer. The shape of an acoustic field, peak pressure, and acoustic pressure distribution were compared with numerical simulation. The NFL was 32 mm, the beam width was 5 mm, focal area was $40\;mm^2$, and peak pressure was 5.5 MPa. With heating by using developed transducer, the temperature increased up to $33^{\circ}C$ at focal zone. As a result of this study, the usefulness of suggested transducer for prostate cancer hyperthermia was confirmed by the acoustic field analysis and the heating test with TMM(tissue mimicking) phantom.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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• pp.297.2-297.2
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• 2016

Photoacoustic generation of ultrasound is an effective approach for development of high-frequency and high-amplitude ultrasound transmitters. This requires an efficient energy converter from optical input to acoustic output. For such photoacoustic conversion, various light-absorbing materials have been used such as metallic coating, dye-doped polymer composite, and nanostructure composite. These transmitters absorb laser pulses with 5-10 ns widths for generation of tens-of-MHz frequency ultrasound. The short optical pulse leads to rapid heating of the irradiated region and therefore fast thermal expansion before significant heat diffusion occurs to the surrounding. In this purpose, nanocomposite thin films containing gold nanoparticles, carbon nanotubes (CNTs), or carbon nanofibers have been recently proposed for high optical absorption, efficient thermoacosutic transfer, and mechanical robustness. These properties are necessary to produce a high-amplitude ultrasonic output under a low-energy optical input. Here, we investigate carbon nanotube (CNT)-polydimethylsiloxane (PDMS) composite transmitters and their nanostructure-originated characteristics enabling extraordinary energy conversion. We explain a thermoelastic energy conversion mechanism within the nanocomposite and examine nanostructures by using a scanning electron microscopy. Then, we measure laser-induced damage threshold of the transmitters against pulsed laser ablation. Particularly, laser-induced damage threshold has been largely overlooked so far in the development of photoacoustic transmitters. Higher damage threshold means that transmitters can withstand optical irradiation with higher laser energy and produce higher pressure output proportional to such optical input. We discuss an optimal design of CNT-PDMS composite transmitter for high-amplitude pressure generation (e.g. focused ultrasound transmitter) useful for therapeutic applications. It is fabricated using a focal structure (spherically concave substrate) that is coated with a CNT-PDMS composite layer. We also introduce some application examples of the high-amplitude focused transmitter based on the CNT-PDMS composite film.

• 식품과학과 산업
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• 제53권3호
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• pp.277-283
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• 2020

식품의 보존성 및 안전성 증대를 위해 살균이 필수적이다. 일반적으로 가열 살균 기술이 가장 많이 사용되고 있으나, 공정 중 식품의 품질 저하를 막기 위한 살균 기술로 신공정 기술을 활용한 비가열 살균 기술의 중요성이 대두되고 있다. 그 중에서도 초음파 기술은 특유의 캐비테이션 현상으로 미생물의 파괴가 촉진되어 살균 효과를 내는 것으로 알려져 있다. 초음파 기술 단독으로는 사멸 효과가 낮으며, 다양한 공정기술과 함께 적용하여 사멸 효과를 극대화할 수 있는 기술 개발을 위한 연구가 활발히 진행되고 있다. 초음파와 함께 처리할 수 있는 공정으로는 가열, 고압, 화학적 처리 등 전통적인 살균 방법 뿐 아니라 자외선 조사, PEF 등 신공정 기술이 있다. 초음파 기술을 적용한 다른 공정과 달리 살균 기술은 아직 실험실 수준에 머물러 있어 산업적 적용을 위한 장치의 개발, 최적 공정 확립 등 추가 연구가 필요하다.

• 제어로봇시스템학회논문지
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• 제13권3호
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• pp.218-223
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• 2007

The dissipation of high-power ultrasonic energy at the faces of the defect causes an increase in temperature. It is resulted from localized selective heating in the vicinity of cracks because of the friction effect. In this paper the measurement of size and direction of crack using UET(Ultrasound Excitation Thermography) is described. The ultrasonic pulse energy is injected into the sample in one side. The hot spot, which is a small area around the crack tip and heated up highly, is observed. The hot spot, which is estimated as the starting point of the crack, is seen in the nearest position from the ultrasonic excitation point. Another ultrasonic pulse energy is injected into the sample in the opposite side. The hot spot, the ending point of the crack, is seen in the closest distance from the injection point also. From the calculation of the coordinates of both the first hot spot and the second hot spot observed, the size and slope of the crack is estimated. In the experiment of STS fatigue crack specimen(thickness 14mm), the size and the direction of the crack was measured.