• Title/Summary/Keyword: UTD

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Antenatally detected urinary tract dilatation: a pediatric nephrologist's point of view

  • Hyung Eun Yim
    • Childhood Kidney Diseases
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    • v.28 no.1
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    • pp.1-7
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    • 2024
  • Antenatally diagnosed urinary tract dilatation (UTD), previously referred to as antenatal hydronephrosis, is the most commonly detected abnormality by prenatal ultrasonography. Several grading systems have been developed for the classification of antenatal UTD using prenatal and postnatal ultrasonography. UTD comprises a wide variety of congenital abnormalities of the kidney and urinary tract ranging from transient UTD to more significant abnormalities such as vesicoureteral reflux, ureteropelvic junction obstruction, ureterocele, ureterovesical junction obstruction, posterior urethral valves, and non-refluxing megaureter. Optimizing the evaluation of antenatally detected UTD is essential to recognize children with important disorders while avoiding excessive investigations. Conservative approach with close follow-up is increasingly accepted as an appropriate treatment option for patients with asymptomatic vesicoureteral reflux and ureteropelvic junction obstruction in recent years. However, predicting permanent kidney damage in an unselected group of children with antenatal UTD is still challenging. The management and follow-up of children with UTD should be individualized based on recommendations from a pediatric nephrologist, a pediatric urologist, or both. Future research directed at predicting long-term outcomes of children diagnosed with UTD from mild findings to severe disease is needed to refine management for those at higher risk of kidney disease progression.

UTD-Supplemented Mode-matching Method Analysis of High-Frequency Wave Coupling into Large Parallel Plate Waveguides (모스정합을 결합한 UTD에 의한 큰 평행도파관의 고주파간섭 해석)

  • 권도훈;선영식;명노훈
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.31A no.10
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    • pp.48-53
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    • 1994
  • The problem of a plane wave impinging upon a semi-infinite paralle-plate waveguide is investigated. The interior fields can be analyzed by converting the initial field into vaveguide modes. Kirchhoff approximation is usually made at the waveguide aperture in the literature. In this paper, a modified approximation is made using the Uniform Gemetrical Theory of Diffraction(UTD). Numerical results show excellent agreement between UTD-supplemented mode-matching solution and UTD solution.

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Multiple Effects of a Novel Epothilone Analog on Cellular Processes and Signaling Pathways Regulated by Rac1 GTPase in the Human Breast Cancer Cells

  • Zhang, Hong;An, Fan;Tang, Li;Qiu, Rongguo
    • The Korean Journal of Physiology and Pharmacology
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    • v.18 no.2
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    • pp.109-120
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    • 2014
  • The epothilones are a class of microtubule inhibitors that exhibit a strong antitumor activity. UTD2 is a novel epothilone analog generated by genetic manipulation of the polyketide biosynthetic gene cluster. This study investigated the effects of UTD2 on the actin cytoskeleton and its critical regulators, and the signaling pathways which are essential for cell motility, growth and survival in MCF-7 breast cancer cells. Results showed that UTD2 inhibited the cellular functions of actin cytoskeleton, such as wound-closure, migration and invasion, as well as adhesion. Our study further demonstrated that UTD2 suppressed Rac1 GTPase activation and reduced the activity of PAK1, which is a downstream effector of Rac1, while the activity of Cdc42 was not affected. Additionally, the phosphorylation of p38 and ERK were significantly inhibited, but the phosphorylation of JNK remained the same after UTD2 treatment. Moreover, UTD2 inhibited the activity and mRNA expression of MMP-2, which plays a key role in cell motility. UTD2 also reduced the phosphorylation of Akt, which is an important signaling kinase regulating the cell survival through Rac1. Furthermore, UTD2 interrupted the synergy between Rac1 and Raf in focus formation assays. Taken together, these results indicated that UTD2 exerted multiple effects on the actin cytoskeleton and signaling pathways associated with Rac1. This study provided novel insights into the molecular mechanism of the antineoplastic and antimetastatic activities of epothilones. Our findings also suggest that the signaling pathways regulated by Rac1 may be evaluated as biomarkers for the response to therapy in clinical trials of epothilones.

UTD Analysis of the Subreflector of an Offxet Dual Reflector Antenna Mounted on a Satellite (UTD를 이용한 위성 탑재용 옵셋 복반사판 안테나의 부반사판 해석)

  • 임규태;이상설
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.32A no.1
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    • pp.79-88
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    • 1995
  • A subreflector of an offset dual reflecor antenna system mounted on satelite is analyzed by Uniform Geometrical Theory of Diffraction(UTD). In order to get the total electric field at an observation point, the reflected field and the diffracted fields obtained by UTD are summed. The reflected point and the diffracted points which have to satisfy nonlinear equations are obtained by numerical methods. The numerical results show taht diffracted fields eliminate the discontinuity of reflected fields at the shadow boundary. To show the validity of our results, the field pattern of the symmetric hyperboloidal reflector is computed and compared with S. W. Lee et al.'s results. At various obsevation angles, radiation patterns of offset ellipsoidal subreflectors offseted by a circular corn and by an elliptic corn are obrained, repectivelly.

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Classification of Behavior of UTD Data using LSTM Technique (LSTM 기법을 적용한 UTD 데이터 행동 분류)

  • Jeung, Gyeo-wun;Ahn, Ji-min;Shin, Dong-in;Won, Geon;Park, Jong-bum
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2018.10a
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    • pp.477-479
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    • 2018
  • This study was carried out to utilize LSTM(Long Short-Term Memory) technique which is one kind of artificial neural network. Among the 27 types of motion data released by the UTD(University of Texas at Dallas), 3-axis acceleration and angular velocity data were applied to the basic LSTM and Deep Residual Bidir-LSTM techniques to classify the behavior.

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A Unified Time-domain Channel Estimator for OFDM based Ubiquitous Broadband Access (OFDM 기반의 유비쿼터스 광대역 접속을 위한 단일화 시간영역 채널 추정기)

  • Seo, Jeong-Wook;Kwak, Jae-Min;Kim, Dong-Ku
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.47 no.1
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    • pp.19-24
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    • 2010
  • This paper proposes a unified time-domain channel estimator (UTD-CE) for ubiquitous wireless broadband access based on orthogonal frequency division multiplexing (OFDM) systems. As a part of a software radio platform for ubiquitous services, the proposed UTD-CE can be exploited with the simply changeable parameters, pilot symbols and pilot subcarriers allocation, which are usually different according to the system specifications such as IEEE802.11x WiFI, IEEE802.16x WiMAX, DMB, Media FLO, DVB-H, etc. Given the pilot information, the channel frequency responses (CFRs) of data subcarriers will be analogously estimated by Wiener filtering and discrete Fourier transform (DFT)-based interpolation in the UTD-CE. Simulation results indicate that the proposed method significantly outperforms the conventional time-domain channel estimator when the pilot information is changed.

Electromagnetic scattering characteristics of a hyperbolic reflector antenna accounting for the UTD higher order diffraction (UTD 고차회절을 고려한 쌍곡면 반사판 아테나의 전자파 산란 특성)

  • 최재훈;이병우;이상설
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.33A no.5
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    • pp.85-93
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    • 1996
  • The far-zone scattered field patterns of a hyperbolic reflector antenna are analyzed by using uniform geometrical theory of diffraction(UTD). The main objective of this paper is to obtain the higher order diffraction contributions which provide the continuity over the shadow boundaries of the first order solution. to obtain the scattered magnetic field characteristics, the scattered field components of the secodn-order diffraction, diffraction-reflection, diffraction-reflection-diffraction terms are added to the result of the previous research. The results of the present research are compared to those of the first order solution and the method of moments. One can observe the improvemtn of the current approach over the first order solution. also, the results of the present method agree very well with those of the moment methods especially in the transition regions near the first order diffraction shadow boundaries.

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The Analysis of Scattering Characteristics of a Prime-focus Offset Parabolic Antenna with a Shaped Edge Structure (정형 모서리 구조를 갖는 옵\ulcornerV 파라볼릭 안테나의 산란 특성 해석)

  • 박대성;김형규;최재훈
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.10 no.3
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    • pp.412-418
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    • 1999
  • The scattering characteristics of a prime-focus offset-parabolic antenna are analyzed using UTD. First, ray tracing method is used to locate the shadow boundaries, and then UTD is utilized to evalute the far-zone scattered magnetic field pattern. The field components included in the UTD analysis are the reflected, edge diffracted and creeping waves. The effects of circular caps attached to both edges of a prime-focus offset-parabolic antenna are investigated by comparing the scattered magnetic field patterns with those of a knife edge parabolic reflector.

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Analysis of Corugated Surface Wave Antenna Using Hybrid MOM/UTD Method (하이브리드 MOM/UTD 방법을 이용한 주름진 표면파 안테나의 해석)

  • Kim, Joong-Pyo;Lee, Chang-Won;Son, Hyon
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.10 no.3
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    • pp.359-367
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    • 1999
  • The analysis of a surface wave antenna with the corrugated ground plane fed by a parallel-plate waveguide is considered. An equivalent theorem Is employed to subdivide the original problem into three regions for the simple analysis : one concerning the geometry inside the shorted parallel-plate(Internal region 1), one concerning the geometry of the corrugation(Internal region 2), and one concerning the geometry of the conducting wedge(External region). The hybrid method of moment(MOM)/uniform geometrical theory of diffraction(UTD) method is applied to analyze a corrugated surface wave antenna with the end-fire radiation. Our numerical results are very well matched with those of the previous experiment, better results are obtained when compared with those of the previous simple equivalent current approach. Also, we can obtain the parameters to design an effective end-fire corrugated surface wave antenna.

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User-Body Shadowing Analysis Technique in Ship Environment Based on the Uniform Geometrical Theory of Diffraction (균일 회절 이론을 이용한 선박 환경에서의 단말기 사용자 쉐도잉 분석 기법)

  • Kim, Chang-Hoe;Jung, Jae-Hoon;Lee, Seong Ro;Kim, Seong-Cheol
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.39C no.11
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    • pp.1209-1215
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    • 2014
  • The Uniform Geometrical Theory of Diffraction(UTD) is an effective technique to analyze the radio wave by ray-based calculation of the diffraction coefficient and the reflection coefficient. In this paper, user body shadowing based on the UTD is investigated when the user is close to the mobile device. Two cases are introduced. One is that the user is calling with the mobile attached to the ear(Head Model). The other is that the mobile is located about 15cm away from the user's chest(Chest Model) Radiation Model and Scattering Model are applied to these cases presenting which model is applicable.