• 제목/요약/키워드: US aid

검색결과 114건 처리시간 0.025초

Comparative co-expression analysis of RNA-Seq transcriptome revealing key genes, miRNA and transcription factor in distinct metabolic pathways in diabetic nerve, eye, and kidney disease

  • Asmy, Veerankutty Subaida Shafna;Natarajan, Jeyakumar
    • Genomics & Informatics
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    • 제20권3호
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    • pp.26.1-26.19
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    • 2022
  • Diabetes and its related complications are associated with long term damage and failure of various organ systems. The microvascular complications of diabetes considered in this study are diabetic retinopathy, diabetic neuropathy, and diabetic nephropathy. The aim is to identify the weighted co-expressed and differentially expressed genes (DEGs), major pathways, and their miRNA, transcription factors (TFs) and drugs interacting in all the three conditions. The primary goal is to identify vital DEGs in all the three conditions. The overlapped five genes (AKT1, NFKB1, MAPK3, PDPK1, and TNF) from the DEGs and the co-expressed genes were defined as key genes, which differentially expressed in all the three cases. Then the protein-protein interaction network and gene set linkage analysis (GSLA) of key genes was performed. GSLA, gene ontology, and pathway enrichment analysis of the key genes elucidates nine major pathways in diabetes. Subsequently, we constructed the miRNA-gene and transcription factor-gene regulatory network of the five gene of interest in the nine major pathways were studied. hsa-mir-34a-5p, a major miRNA that interacted with all the five genes. RELA, FOXO3, PDX1, and SREBF1 were the TFs interacting with the major five gene of interest. Finally, drug-gene interaction network elucidates five potential drugs to treat the genes of interest. This research reveals biomarker genes, miRNA, TFs, and therapeutic drugs in the key signaling pathways, which may help us, understand the processes of all three secondary microvascular problems and aid in disease detection and management.

A Review on Advanced Methodologies to Identify the Breast Cancer Classification using the Deep Learning Techniques

  • Bandaru, Satish Babu;Babu, G. Rama Mohan
    • International Journal of Computer Science & Network Security
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    • 제22권4호
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    • pp.420-426
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    • 2022
  • Breast cancer is among the cancers that may be healed as the disease diagnosed at early times before it is distributed through all the areas of the body. The Automatic Analysis of Diagnostic Tests (AAT) is an automated assistance for physicians that can deliver reliable findings to analyze the critically endangered diseases. Deep learning, a family of machine learning methods, has grown at an astonishing pace in recent years. It is used to search and render diagnoses in fields from banking to medicine to machine learning. We attempt to create a deep learning algorithm that can reliably diagnose the breast cancer in the mammogram. We want the algorithm to identify it as cancer, or this image is not cancer, allowing use of a full testing dataset of either strong clinical annotations in training data or the cancer status only, in which a few images of either cancers or noncancer were annotated. Even with this technique, the photographs would be annotated with the condition; an optional portion of the annotated image will then act as the mark. The final stage of the suggested system doesn't need any based labels to be accessible during model training. Furthermore, the results of the review process suggest that deep learning approaches have surpassed the extent of the level of state-of-of-the-the-the-art in tumor identification, feature extraction, and classification. in these three ways, the paper explains why learning algorithms were applied: train the network from scratch, transplanting certain deep learning concepts and constraints into a network, and (another way) reducing the amount of parameters in the trained nets, are two functions that help expand the scope of the networks. Researchers in economically developing countries have applied deep learning imaging devices to cancer detection; on the other hand, cancer chances have gone through the roof in Africa. Convolutional Neural Network (CNN) is a sort of deep learning that can aid you with a variety of other activities, such as speech recognition, image recognition, and classification. To accomplish this goal in this article, we will use CNN to categorize and identify breast cancer photographs from the available databases from the US Centers for Disease Control and Prevention.

산욕 초기 입원치료를 받은 산모들의 한방 치료 만족도 조사 (A Study about the Satisfaction of Oriental Medical Postpartum Care)

  • 박지영;박정경;박가영;김태희
    • 대한한방부인과학회지
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    • 제22권4호
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    • pp.173-186
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    • 2009
  • Purpose: 1. To analyze the satisfaction and cognition of postpartum care and to aid the spread of oriental medicine in postpartum care. 2. Get a basic guideline of O.M.D's postpartum care. Methods: We studied the satisfaction and cognition of postpartum care with questionnaire from January 2009 to August 2009, who was treated in ○○ Oriental Medical Postpartum care center during 2 weeks. 61 puerperants answered us. Results: 1. In choosing Postpartum care center, puerperants concerned about new born infants' care(50.8%) and treatment for discomfort after delivery(27.86%). 2. 22 puerperants(36.6%) had a positive view in folk remedy for postpartum care and 34 puerperants(55.73%) thought it would be good to eliminate edema and loose weight. 3. Most of puerperants(80.32%) chose oriental medical postpartum care because they wanted to receive oriental medical treatment. 4. 5 puerperants(8.19%) were very satisfied with oriental medical postpartum care than other type of postparum care which they experienced at first delivery. 47(77.04%) were satisfied, 2(3.27%) were unsatisfied and no one was very satisfied. 5. To the questionnaire about the effect of strength recovery, lochia excretion, edema limination, increasing amount of breastmilk, reducing arthralgia, about 36.8% puerperants showed positive view. 6. The positive view about Acupuncture, cupping, moxibustion, herbal treatment was, respectively, 90.16%, 49.18%, 73.77%, 86.88%. Conclusion: Puerperants were satisfied with oriental medical postpartum care and had positive cognition in oriental medical treatment. There is much capability for extension of oriental medicine in postpartum care. So continuous concern, systemic development and publicity about oriental medical postpartum care are required.

Application of a Semi-Physical Tropical Cyclone Rainfall Model in South Korea to estimate Tropical Cyclone Rainfall Risk

  • Alcantara, Angelika L.;Ahn, Kuk-Hyun
    • 한국수자원학회:학술대회논문집
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    • 한국수자원학회 2022년도 학술발표회
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    • pp.152-152
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    • 2022
  • Only employing historical data limits the estimation of the full distribution of probable Tropical Cyclone (TC) risk due to the insufficiency of samples. Addressing this limitation, this study introduces a semi-physical TC rainfall model that produces spatially and temporally resolved TC rainfall data to improve TC risk assessments. The model combines a statistical-based track model based on the Markov renewal process to produce synthetic TC tracks, with a physics-based model that considers the interaction between TC and the atmospheric environment to estimate TC rainfall. The simulated data from the combined model are then fitted to a probability distribution function to compute the spatially heterogeneous risk brought by landfalling TCs. The methodology is employed in South Korea as a case study to be able to implement a country-scale-based vulnerability inspection from damaging TC impacts. Results show that the proposed model can produce TC tracks that do not only follow the spatial distribution of past TCs but also reveal new paths that could be utilized to consider events outside of what has been historically observed. The model is also found to be suitable for properly estimating the total rainfall induced by landfalling TCs across various points of interest within the study area. The simulated TC rainfall data enable us to reliably estimate extreme rainfall from higher return periods that are often overlooked when only the historical data is employed. In addition, the model can properly describe the distribution of rainfall extremes that show a heterogeneous pattern throughout the study area and that vary per return period. Overall, results show that the proposed approach can be a valuable tool in providing sufficient TC rainfall samples that could be an aid in improving TC risk assessment.

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A Review on Detection of COVID-19 Cases from Medical Images Using Machine Learning-Based Approach

  • Noof Al-dieef;Shabana Habib
    • International Journal of Computer Science & Network Security
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    • 제24권3호
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    • pp.59-70
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    • 2024
  • Background: The COVID-19 pandemic (the form of coronaviruses) developed at the end of 2019 and spread rapidly to almost every corner of the world. It has infected around 25,334,339 of the world population by the end of September 1, 2020 [1] . It has been spreading ever since, and the peak specific to every country has been rising and falling and does not seem to be over yet. Currently, the conventional RT-PCR testing is required to detect COVID-19, but the alternative method for data archiving purposes is certainly another choice for public departments to make. Researchers are trying to use medical images such as X-ray and Computed Tomography (CT) to easily diagnose the virus with the aid of Artificial Intelligence (AI)-based software. Method: This review paper provides an investigation of a newly emerging machine-learning method used to detect COVID-19 from X-ray images instead of using other methods of tests performed by medical experts. The facilities of computer vision enable us to develop an automated model that has clinical abilities of early detection of the disease. We have explored the researchers' focus on the modalities, images of datasets for use by the machine learning methods, and output metrics used to test the research in this field. Finally, the paper concludes by referring to the key problems posed by identifying COVID-19 using machine learning and future work studies. Result: This review's findings can be useful for public and private sectors to utilize the X-ray images and deployment of resources before the pandemic can reach its peaks, enabling the healthcare system with cushion time to bear the impact of the unfavorable circumstances of the pandemic is sure to cause

Assessment of Occupational Health Risks for Maintenance Work in Fabrication Facilities: Brief Review and Recommendations

  • Dong-Uk Park;Kyung Ehi Zoh;Eun Kyo Jeong;Dong-Hee Koh;Kyong-Hui Lee;Naroo Lee;Kwonchul Ha
    • Safety and Health at Work
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    • 제15권1호
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    • pp.87-95
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    • 2024
  • Background: This study focuses on assessing occupational risk for the health hazards encountered during maintenance works (MW) in semiconductor fabrication (FAB) facilities. Objectives: The objectives of this study include: 1) identifying the primary health hazards during MW in semiconductor FAB facilities; 2) reviewing the methods used in evaluating the likelihood and severity of health hazards through occupational health risk assessment (OHRA); and 3) suggesting variables for the categorization of likelihood of exposures to health hazards and the severity of health effects associated with MW in FAB facilities. Methods: A literature review was undertaken on OHRA methodology and health hazards resulting from MW in FAB facilities. Based on this review, approaches for categorizing the exposure to health hazards and the severity of health effects related to MW were recommended. Results: Maintenance workers in FAB facilities face exposure to hazards such as debris, machinery entanglement, and airborne particles laden with various chemical components. The level of engineering and administrative control measures is suggested to assess the likelihood of simultaneous chemical and dust exposure. Qualitative key factors for mixed exposure estimation during MW include the presence of safe operational protocols, the use of air-jet machines, the presence and effectiveness of local exhaust ventilation system, chamber post-purge and cooling, and proper respirator use. Using the risk (R) and hazard (H) codes of the Globally Harmonized System alongside carcinogenic, mutagenic, or reprotoxic classifications aid in categorizing health effect severity for OHRA. Conclusion: Further research is needed to apply our proposed variables in OHRA for MW in FAB facilities and subsequently validate the findings.

향약구급방(鄕藥救急方)에 대(對)한 고증(考證) (A research on Hyang-Yack-Ku-Keup-Bang(鄕藥救急方) (Restoration and Medico-Historic Investigation))

  • 신영일
    • 한국한의학연구원논문집
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    • 제2권1호
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    • pp.71-83
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    • 1996
  • Hyang-Yack-Ku-Keup-Bang(鄕藥救急方) is our own, medical work written about the middle of the time of Korea Dynasty. I restored and researched this book because it needed to be illuminated about its medico-historic value and then I came to some conclusions as follows. 1. Hyang-Yack-Ku-Keup-Bang was published in Dae-jang-do-kam(大藏都監) of Kanghaw island(江華島) about the middle of Korea Dynasty. Choi Ja-ha(崔自河) republished it on original publication ground in Euiheung(義興) of Kyungsang-Province(慶尙道) in July, Taejong's(太宗) 17th year of Chosen Dynasty (A.D.1417) and this book was published again in Chungcheng Province(忠淸道) in Sejong's(世宗) 9th year(A.D.1427). The book published in Taejong's days was in the possession of books department of Kung-nae-cheng(宮內廳) in Japan and was the oldest medical book of existing ones. 2. Bang-Jung-Hyang-Yack-Mock-Cho-Bu(方中鄕藥目草部) of this book was originally intended to be adjusted in each division with the title of Bang-Jung-Hyang-Yack-Mock(方中鄕藥目). But Herb part(草部) only followed editing progress of Jeung-Lew-Bon-Cho(證類本草), the rest is not divided into each part and is together arranged at the below of Herb part with the title of Bang-Jung-Hyang-Yack-Mock-Cho-Bu. The Korean inscriptions on some drugstuffs in this book are different between Native Name(鄕名) of three volumes of provisions and general-spoken(俗云) of Bang-Jung-Hyang-Yack-Mock-Cho-Bu. In this, it is estimated that the publishing time and editor of tile volume of provisions and Bang-Jung-Hyang-Yack-Mock-Cho-Bu are different. I think Choi Ja-ha compiled this behind three volumes of provisions when he published. 3. This book picked some prescriptions which consisted of obtainable drugs with ease in Korea in the books of Chell-Keum-Yo-Bang(千金要方), Oi-Dae-Bi-Yo(外臺秘要), Tae-Peong-Sung-Hye-Bang(太平聖惠方), Ju-Hu-Bang(?後方), Kyung-Hum-Yang- Bang(經驗良方) Bo-Je-Bon-Sa-Bang(普濟本事方) Bi-Ye-Baik-Yo-Bang(備預百要方) and so on and got together our own prescriptions. On the whole Bi-Ye-Baik-Yo-Bang was a chief referrence book, On this, other books referred to and corrected. 4. In provisions quoted from Hyang-Yack-Jip-Sung-Bang(鄕藥集成方), there are seven provisions; leg-paralysis part, coughing part, headache part, obstetrics part, etc. don't show in this book. This is why Choi Ja-ha published only certain texts on Dae-jang-do-kam edition his own posession. So we can think the existing edition has a little misses compared with original edition. 5. This book recorded only names of drugstuffs in animal drug department like fowls, crab, goldbug, earthworm, etc. and didn't tell us ways of taking those. This is effect of Buddhist culture on medicine. This is efforts to practice 'Don't murder';one of Five Prohibition of Buddhism. 6. Beacause this book was published at the time, when our originative medicine would be set forth. This followed the Chinese ways in Theory, Treatment, Prescription and used 'Hyang Yack' in Medication out of theory of Korean medicine, which was a transitional form. So this is all important material which tell us aspects of development of 'Hyang Yack' the middle of Korea Dynasty.and this is also the beginning of originative, medical works like Dong-Eui-Bo-Kam(東醫寶鑑), Dong-Eui-Su-Bo-Won(東醫壽世保元). 7. There are few contents based on 'Byen-Jeung-Lon-Chi(辨證論治)'in this book. So we can see this book is not for doctors who study medical thoughts but for general public who suffer from diseases resulted from war. Because this book was written for a first-aid treatmeant, this is an index of medical service for the people those days. And this is also an useful datum for first-aid medicine or military medicine in these modern days. 8. Nowadays, parts of learned world of Korean medicine disregard essential theories and want to explain Korean medicine only by the theories or the methods of Western medicine. Moreover they don't adopt Chinese and Japanese theorys & thoughts about Oriental medicine in our own style and just view in there level. What was worse, there is a growing tendency for them to indulge in a trimming policy of scholarship and to take others' ideas. I think these trends to ignore our own medical thoughts involving growth of 'Hyang Yack' in the middle of Korea Dynasty, Dong-Eui-Bo-Kam and Dong-Eui-Su-Se-Bo-Won. So we, as researchers of Korean medicine, must get out of this tendency, and take over brilliant tradition and try to develop originative Korean medicine.

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미·중 무역 분쟁 관련 환구시보(環球時報) 사설 비교를 통한 비판적 담화분석 - 「용타항미원조적의지타대미무역전(用打抗美援朝的意志打對美貿易戰)」 중심으로 - (A Critical Discourse Analysis Through Comparisons Between Editorials of The Global Times, Huánqiú Shíbào on the 2018 United States-China Trade War)

  • 최태훈
    • 비교문화연구
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    • 제52권
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    • pp.165-194
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    • 2018
  • 본 연구는 환구시보 4월 7일 "용타항미원조적의지타대미무역전(用打抗美援朝的意志打對美貿易戰)" 사설에 대하여 비판적 담화분석의 접근법을 활용하여 텍스트 기술, 상호텍스트성, 사회문화적 수행 설명으로 구분하여 분석하였다. 본 사설은 '전쟁(戰爭)'과 관련된 어휘와 프레임을 집중적으로 사용하고 있다. 첫째, "무역전(貿易戰)"과 "항미원조(抗美援朝)"는 은유와 전쟁프레임을 보여주는 예이다. 둘째, "전략(戰略)"은 미국과 중국에 각각 부정적, 긍정적으로 사용되고 있다. 셋째, 다양한 전쟁 용어가 사용되었다. 넷째, '인유법(引喩法)'을 살펴보면, 전쟁관련 표현이 보인다. 본 사설의 상호텍스트성에서 두 가지 결과를 얻을 수 있었다. 첫째, 환구시보가 '대등한 보복'을 줄곧 사용하고 있다. 이유는 자신의 반격을 정당화하고, 그런 중국이 하는 전쟁은 '자위적 차원의 반격전(自衛反擊戰)'이 되도록 포장해주기 위함이다. 둘째, '싸우기는 싫은데, 싸움이 두렵지는 않다'라는 표현이 여러 사설에서 반복되었다. 그 이유는 다음과 같다. (1) 인민의 결집을 호소. (2) 공포심을 일으켜, 그들이 결집해야만 하는 이유를 암암리에 부여. (3) "두렵지 않다"를 통해 중국은 체면을 차리고, 미국에게는 "싸우기 싫다"는 '싸인'을 보내기 위함이다. 맥락상 같은 논지가 약 3개월(2018.03.23.-06.17)의 시간차를 두고 9개 사설에서 비슷한 표현으로 보이는 것은 상호텍스트성의 예라 할 것이다. 본 사설의 사회문화적 수행은 중국 정부의 패권 이데올로기를 전파함에 있다. 첫째, 핵심 국책사업 '중국제조(中國製造)2025'는 절대 포기할 수 없음을 분명히 밝힌 것이다. 둘째, 사설은 "항미원조(抗美援朝)"를 소명하여 미국을 비난 협박하고, 민심의 이반을 다독이며 결집을 호소, 시진핑 정부에 힘을 실어 주고자 하는 의도이다. 셋째, 중국은 미국과의 협상의 여지를 열어두고자 하고 있다.

한국수산업의 해외진출전략에 관한 연구 (Foreign Entry Strategies for Korean Fishery Firms)

  • 김회천
    • 수산경영론집
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    • 제15권1호
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    • pp.131-153
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    • 1984
  • Fishery resources are still abundant compared with other resources and the possibility of exploitation is probably great. The Korean fishery industry has grown remarkably since 1957, and Korea is ranked as one of the major fishery countries. Its of fishery products reached the 9th in the world and the value of exports was 5th in 1982. But recently a growth rate has slowed down, due to the enlargement of territorial seas by the declaration of the 200 mile, Exclusive Economic Zone, the tendency to develop fishery resources strate-gically in international bargaining, the change in function of the international organizations, the expansion of regulated waters, the illegal arrest of our fishing boats, the rapid rise in oil prices, and the fall in fish prices, the development of fishery resources as a symbol of nationalism, the fishing boats decreptitude, the rise of crew wages, regulations on fishing methods, fish species, fishing season, size of fish, and mesh size, fishing quotas and the demand of excessive fishing royalties. Besides the the obligation of coastal countries, employing crews of their host countries is also an example of the change in the international environment which causes the aggravation of foreign profit of fishing firms. To ameliorate the situation, our Korean fishery firms must prepare efficient plans and study systematically to internationalize themselves because such existing methods as conventional fishing entry and licence fishing entry are likely to be unable to cope with international environmental change. Thus, after the systematic analysis of the problem, some new combined alternatives might be proposed. These are some of the new schemes to support this plan showing the orientation of our national policy: 1. Most of the coastal states, to cope with rapid international environmental change and to survive in the new era of ocean order, have rationalized their higher governmental structure concerning the fishery industries. And the coastal countries which are the objectives of our expecting entry, demand excessive economic and technical aid, limit the number of fishing boats’entry and the use of our foreign fishing bases, and regulate the membership of the international fishery commissions. Especially, most of the coastal or island countries are recently independent states, which are poorer in national budget, depend largely on fishing royalties and licence entry fees as their main resources of national finance. 2. Alternatives to our entry to deep sea fishing, as internationalization strategies, are by direct foreign investment method. About 30 firms have already invested approximately US $ 8 million in 9 coastal countries. Areas of investment comprise the southern part of the Atlantic Ocean, the Moroccan sea and five other sea areas. Trawling, tuna purse seining and five other fields are covered by the investment. Joint-venture is the most prominent method of this direct investment. If we consider the number of entry firms, the host countries, the number of seas available and the size of investment, this method of cooperation is perhaps insufficient so far. Our fishery firms suffer from a weakness in international competitive ability, an insufficiency of information, of short funds, incompetency in the market, the unfriendliness of host coastal countries, the incapability of partners in joint-ventures and the political instability of the host countries. To enlarge our foreign fishing grounds, we are to actively adopt the direct investment entry method and to diversity our collaboraboration with partner countries. Consequently, besides proper fishing, we might utilize forward integration strategies, including the processing fied. a. The enterprise emigration method is likely to be successful in Argentina. It includes the development of Argentinian fishing grounds which are still not exploited in spite of abundant resources. Besides, Arentina could also be developed as a base for the exploitation of the krill resources and for further entries into collaboration with other Latin American countries. b. The co-business contract fishing method works in American territorial seas where American fishermen sell their fishery products to our factory ships at sea. This method contributes greatly to obtaining more fishing quotas and in innovation bottom fishing operation. Therefore we may apply this method to other countres to diffuse our foreign fishing entry. c. The new fishing ground development method was begun in 1957 by tuna long-line experimental fishing in the Indian Ocean. It has five fields, trawling, skipjack pole fishing and shrimp trawling, and so on. Recently, Korean fisheries were successful in the development of the Antarctic Ocean krill and tuna purse seining. 3. The acceleration of the internationalization of deep sea fishing; a. Intense information exchange activities and commission participation are likely to be continues as our contributions to the international fishery organizations. We should try to enter international fishery commissions in which we are not so far participating. And we have to reform adequately to meet the changes of the function of the international commissions. With our partner countries, we ought to conclude bilateral fishery agreements, thus enlarging our collaboration. b. Our government should offer economic and technical aids to host countries to facilitate our firms’fishery entry and activities. c. To accelerate technical innovation, our fishery firms must invest greater amount in technical innovation, at the same time be more discriminatory in importing exogeneous fishery technologies. As for fishing methods; expanded use of multi-purpose fishing boats and introduction of automation should be encuraged to prevent seasonal fluctuations in fishery outputs. d. The government should increases financial and tax aid to Korean firms in order to elevate already weak financial structure of Korean fishery firms. e. Finally, the government ought to revise foreign exchange regulations being applied to deep sea fishery firms. Furthermore, dutes levied on foreign purchaed equipments and supplies used by our deep sea fishing boats thould be reduced or exempted. when the fish caught by Korean partner of joint-venture firms is sold at the home port, pusan, import duty should be exempted.

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최적설계 시스템을 이용한 부품에 대한 형상설계 방법론 (Methodology of Shape Design for Component Using Optimal Design System)

  • 이준성;조성규
    • 한국산학기술학회논문지
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    • 제19권1호
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    • pp.672-679
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    • 2018
  • 본 논문은 최적설계 시스템을 이용한 형상설계 방법론에 대해 설명하고 있으며, 일반적으로 3차원 해석은 설계를 위해 반드시 필요하다. 퍼지지식처리 수법과 계산기하학적 기법에 바탕을 둔 자동화된 유한요소 메쉬 생성 기법은 상용화된 유한요소해석코드와 솔리드모델러와 함께 시스템에 결합되어 있다. 또한, 다층형 신경망의 도움과 함께 개발된 시스템은 다차원 설계변수 공간에 존재하는 여러 만족하는 설계해인 디자인윈도우를 얻을 수 있게 해준다. 개발된 최적화 설계 시스템 사용된 부품을 평가하는데 성공적으로 적용하였다. 사이드 하우징 브라켓을 현장에서 사용되어지는 굴삭기의 힘과 유압브레이커의 작용하는 응력을 응력 게이지로 사이드 하우징 브라켓의 크랙 발생부위에 부착하여 최대응력이 얼마나 걸리는지를 측정하였다. 적용하는 대상을 현장에서와 동일한 조건하에서 최대응력이 허용응력보다 같거나 적게 하고, 기존형상 유지, 재질은 SM490, 중량 최소화 안전계수는 3으로 하여, 최대응력 값에 대한 해석을 수행하였다. 구조가 비교적 간단한 36톤용 사이드 하우징 브라켓을 최적화하였지만, 다른 클래스의(톤수 별) 사이드 하우징 브라켓 적용 시 품질향상에 크게 기여하리라 생각된다.