• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 1999.10a
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• pp.289-296
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• 1999

In order to develop and enhance our methodology of seismic design in the next generation thee is a need to analyze the environment chronicles and concept of the seismic design in foreign countries. For this purpose we have researched the cases of U.S.A and Europe. In this paper the emphasis was put on the european seismicity and seismic design practices for building structures. In this study the comparison of seismic design codes in some european countries regarding fundamental period and design base shears leads to the conclusion that there exists remarkable difference in the approaches. Particularly the base shears used in european countries give larger values than the one proposed by UBC 97. Though each european country has established similar seismic design code there are also still large difference in the level of construction technology and societal implementation of seismic codes.

• Development and Reproduction
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• v.12 no.3
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• pp.289-296
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• 2008

BPES (Blepharophimosis/Ptosis/Epicanthus inversus Syndrome) is an autosomal dominant disorder caused by mutations in FOXL2. Affected individuals have premature ovarian failure (POF) in addition to small palpebral fissures, drooping eyelids, and broad nasal bridge. FOXL2 is a member of the forkhead family transcription factors. In FOXL2-deficient ovaries, granulosa cell differentiation dose not progress, leading to arrest of folliculogenesis and oocytes atresia. Using yeast two-hybrid screening of rat ovarian cDNA library with FOXL2 as bait, we found that small ubiquitin-related modifier (SUMO)-conjugating E2 enzyme UBE2I protein interacted with FOXL2 protein. UBE2I also known as UBC9 is an essential protein for processing SUMO modification. Sumoylation is a form of post-translational modification involved in diverse signaling pathways including the regulation of transcriptional activities of many transcriptional factors. In the present study, we confirmed the protein-protein interaction between FOXL2 and UBE2I in human cells, 293T, by in vivo immunoprecipitation. In addition, we generated truncated FOXL2 mutants and identified the region of FOXL2 required for its association with UBE2I using yeast-two hybrid system. Therefore, the identification of UBE2I as an interacting protein of FOXL2 further suggests a presence of novel regulatory mechanism of FOXL2 by sumoylation.

• Journal of Internet Computing and Services
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• v.11 no.3
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• pp.87-103
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• 2010

In the study, we introduce the trend in domestic and foreign web accessibility, as well as the legal system that ensures web accessibility. Based on Korean Web Content Accessibility Guidelines (KWCAG)1.0, we investigated the web content accessibility of 80 tertiary health-care hospitals and general hospitals in Korea. We evaluated accessibility by combining accessibility-based criteria (ABC) with usability-based criteria (UBC). ABC was limited to an alternative text for Guideline 1, using a small number of frames and keyboard accessibility for Guideline 2. UBC checked the voice service (TTS), resizing text, providing multi-lingual websites, and disclosing web accessibility policy. KADO-WAH2.0 was used for representing the compliance rate. The evaluation result was a considerable improvement from previous results, even though the rate of compliance with web accessibility was generally insufficient. There was a significant difference between those medical centers which did and did not comply with web accessibility. Incidentally, many hospitals were found to have attempted to confront and come to terms with web accessibility. In future, the following factors are advisable for medical centers with publicity or public interest: they must employ active and aggressive promotion of establishment of independent accessibility guidelines to secure web accessibility, they should effect an improvement of the realization of web accessibility, there can be constant education and promotion, and there can be an institutional supplementation, as well as others.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.11
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• pp.37-43
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• 2020

The seismic reinforcement ratio of SOC facilities, such as domestic roads and railroads, is 96%. Out of approximately 7 million buildings as of 2016, only 0.51 million buildings with seismic performance were secured. Although the proportion of masonry structures is 38.8% of the total buildings, there is almost no seismic resistance, only 2.0%. To solve the problem in Korea, government-level seismic measures are being promoted, but the situation is insufficient. Overseas, the UBC research team in Vancouver, Canada, has developed and used EDCC to reinforce the seismic performance of masonry buildings. EDCC is a construction material that can secure concrete ductility capability by mixing fibers and secure deformation resistance of concrete through bridging action. It is necessary to examine various materials because EDCC is not used as a spray type of secure seismic reinforcement. In this study, as part of the research and development of spraying materials to improve the durability of masonry buildings, this study examined the spraying characteristics of fiber-reinforced mortar according to fiber use and the viscosity change according to the use of thickener. As a result, the working performance of the fiber-reinforced mortar for seismic reinforcement was improved when using 1% fiber and 1% thickener.

• Korean Journal of Medicinal Crop Science
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• v.11 no.5
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• pp.377-384
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• 2003

Genetic differences among nine land races of Korean ginseng (Panax ginseng C. A. Meyer) were examined using RAPD markers. Land races of Korean ginseng were collected from nine regions in Korea: Cheongwon, Guesan, Geumsan, Namwon, Pochun, Yangju, Yeoncheon, Yeongju. Out of 48 RAPD primers tested, 5 primers (OPA 7, OPA 13, URP 2, URP 3 and UBC 3) produced remarkable bands which showing polymorphisms among evaluated collections. Lower levels of genetic diversity were in detected same land races than among other land races. Genetic differences within and among land races indicate heterogeneity. These results indicate that cultivated ginseng in Korea is heterogeneous. Genetic similarity matrices of RAPD profiles were generated via coefficients of variation and the data were processed by the cluster analysis (UPGMA). When 90 collections were evaluated using selected 5 primers, those were clustered to 5 and 3 subgroups. These differences in genetic variation between land races of Korean ginseng implied the potential source for further breeding of Korean ginseng.

• Journal of the Earthquake Engineering Society of Korea
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• v.10 no.2 s.48
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• pp.39-50
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• 2006

Site response analyses were peformed based on equivalent linear technique using the shear wave velocity profiles of 162 sites collected around the Korean Peninsula. The she characteristics, particularly the shear wave velocities and the depth to bedrock, are compared to those in the western United States. The site coefficients of short period $(F_a)$ and the long period $(F_v)$ obtained from this study were significantly different compared to 1997 Uniform Building Code (1997 UBC). $F_a$ underestimated the motion in shot period ranges and $F_v$ overestimated the motion in mid period ranges in Korean seismic guideline. It is found that the existing Korean seismic design code were is required to be modified considering geological site conditions in Korea for the reliable estimation of sue amplification. Problems of the current seismic design code were dicussed in this paper and the development of site classification method and modification of desing response spectra were discussed in the companion papers(II-Development of Site Classification System and III-Modification of Dosing Response Specra).

• Journal of the Earthquake Engineering Society of Korea
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• v.3 no.1
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• pp.113-122
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• 1999

The importance of the vertical response of a structure was well recognized after the Hyogoken-Nanbu earthquake of Japan. However, most of the seismic design codes does not specified the site sail profiles, and the sail and foundations conditions were mostly neglected in the vertical seismic analyses of a structure. In this paper, the effects of foundation size, sail layer depth under the foundation, foundation embedment and pile foundation on the vertical seismic response spectra for both surface and embedded mat foundation were studied to investigate the effects of the soft soil layer on the vertical response of a structure excited with the vertical components of Taft and El Centro earthquakes, considering the sail profile types of $S_A,S_C,S_E$ in UBC-97, the medium and large size foundations, the soil layer depth under the foundation of 30 and 60m, the foundation embedment of 0 and 15m, and the precast reinforced concrete bearing piles installed in the soft soil deposit. According to the study results, the foundation size has a little effect on the vertical seismic response, However, the soil layer depth under the foundation of 60m has to be considered for the vertical seismic analysis of a structure as for the horizontal one. The embedded pile foundations as well as the surface ones built on the soft soil layer amplified the vertical seismic response of a structure very much.

• Horticultural Science & Technology
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• v.33 no.4
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• pp.598-604
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• 2015

This study was carried out to develop molecular techniques to allow the selection of zygotic seedlings in the early stage of the plant development. We identified 37 pollen-specific molecular markers from RAPD analysis and successfully used them for identification of the zygotic seedlings from various hybrid crosses. Three Satsuma mandarin cultivars ('Morita unshiu', 'Nangan 20' and 'Miyagawawase') were used as mother parents and seven cultivars ('Ponkan', 'Lee', 'Kinokuni', 'Shiranuhi', 'Tamnaneunbong', 'Shinyegam', and 'Sunburst' mandarins) served as pollen parents. PCR analysis showed that 2 primers could identify zygotic hybrid seedlings. Among them, an UBC-27 primer was used to identify the zygotic seedlings from hybrid crosses of "'Nangan 20' ${\times}$ 'Kinokuni'" mandarin, "'Nangan 20 ${\times}$ Ponkan'" mandarin and "'Miyagawawase ${\times}$ Sunburst'" tangerine. In total 29 out of 40 seedlings (73%), 9 out of 47 seedlings (19%), and 13 out of 45 (29%) were identified as zygotic seedlings, respectively. These results can show that the pollen-specific markers selected in this study can be used effectively for early identification of zygotic seedlings from Citrus hybrid crosses.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.5
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• pp.1039-1049
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• 2015

The inflow estimation at large multipurpose dam reservoir is carried out by considering the water balance among the discharge, the storage change during unit time interval obtained from the observed water level near dam structure and area-volume curve. This method can be ideal for level pool reservoir but include potential errors when the inflow is influenced by the water level slope due to backwater effects from upstream flood inflows and strong wind induced by typhoon. In addition, the other uncertainties arisen from the storage reduction due to sedimentation after the dam construction and water level noise due to mechanical vibration transmitted from the electric power generator. These uncertainties impedes the accurate hydraulic inflow measurement requiring exquisite hydrometric data arrangement for reservoir waterbody. In this study, the distributed hydrologic model using UBC-3P boundary setting was applied and its feasibility was evaluated. Finally, the modeling performance has been verified since the calculated determination coefficient has been in between 0.96 to 0.99 after comparing with observed peak inflow and total inflow at Namgang dam reservoir.

• Horticultural Science & Technology
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• v.31 no.6
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• pp.798-806
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• 2013

Precise, fast, and cost-effective identification of crop cultivars is essential for plant breeder's rights. Traditional methods for identification of persimmon cultivars are based on the evaluation of sets of morphological characteristics. However, it is difficult to distinguish closely related cultivars using only morphological traits. This study was conducted to develop DNA markers for identification of the 32 persimmon cultivars in Korea and Japan. A total of 309 randomly amplified polymorphic DNA (RAPD) markers were identified using 40 different random primers. Various number of polymorphic bands ranged from 4 (OPP-08) to 14 (UBC159) were detected with an average of 7.7. Resulting 57 RAPD fragments were selected, and their sequences were determined for developing sequence characterized amplified region (SCAR) markers. As a result, 15 of 57 RAPD fragments were successfully converted to SCAR markers. Single polymorphic bands of the same size as or smaller than the RAPD fragments were amplified depending on SCAR markers. Among these markers, a combination of eight SCAR markers (PS225_200, PSN05_420, PSF13_523, PSN11_540, PS372_567, PS485_569, PSP08_635, and PS631_735) provided sufficient polymorphisms to identify 32 persimmon cultivars. These newly developed markers will be a fast and reliable tool to identify persimmon cultivars.