• Proceedings of the Computational Structural Engineering Institute Conference
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• 1991.10a
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• pp.90-95
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• 1991

The Uniform Building Code (UBC) is the most widely used requirements for earthquake resistant design in the United States. In this paper, a mid-rise steel building is analyzed by applying 12 sets of actual strong-motion earthquake data that have been scaled to acne 2B levels. The simply extrapolated ground motion displacements are used for the dynamic loads. The results of dynamic analyses for a 10-story steel building are compared with the static and dynamic analysis requirements of UBC-88. It was found that computed lateral fortes using UBC-88 static procedure differed by about 60 percent depending on whether the natural period was computed using the UBC empirical method or the UBC recommended Rayleigh's method. The lateral fortes computed from the UBC response spectra were more than 10 times greater than those computed by UBC static procedures. The lateral forces obtained from both linear and nonlinear analyses using 1989 Loma Prieta ground mot ions compared very well with UBC response spectra results.

• The Korean Journal of Nuclear Medicine
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• v.35 no.3
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• pp.192-197
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• 2001

Purpose: Urinary cytology and cystoscopic exam are effective methods for diagnosis of transitional cell carcinoma(TCC). But the former shows drawbacks such as the need for a well-trained examiner, and wide imprecision related to the variability of microscopic exam; the latter is an invasive method. $UBC^{TM}$ test detects the epitope on specific cytokeratin fragments released from epithelium of bladder cancer by immunoradiometric assay. We compared $UBC^{TM}$ test with urinary cytology for diagnosis of TCC to evaluate the utility of $UBC^{TM}$ test. Materials and Methods: Eighty-four patients with hematuria were included in our study. $UBC^{TM}$ tests (IDL Biotech, Sweden) were assayed in mid-stream urine according to the ordinary assay protocol. Nineteen patients were confirmed as TCC by cystoscopic examination and underwent transurethral resection (Group A). Other patients had various benign urinary tract conditions (Group B). Samples were considered positive as the $UBC^{TM}$ concentration was greater than $12{\mu}g/L$. Results: $UBC^{TM}$ levels were significantly different between group A ($95.9{\pm}166.4\;{\mu}g/L$) and group B ($19.2{\pm}85.6{\mu}g/L$) (P<0.001). Sensitivity for diagnosis of TCC was 89.5% (17/19) in UBC test and 47.4% (9/19) in cytology (p<0.05). Specificity for diagnosis of TCC was 81.5% (53/65) in $UBC^{TM}$ test and 100% (65/65) in cytology. $UBC^{TM}$ test was significantly more sensitive in stage Ta, $T_1$ tumors (84.6 vs 38.5%, p<0.05) and in grade I (83.3% vs 16.7%, p<0.05) than cytology. $UBC^{TM}$ test showed a tendency to be more sensitive as the grade was higher (83.3% in Grade I, 90% in Grade II and 100% in Grade III). Conclusion: $UBC^{TM}$ test could be a useful method in distinguishing TCC from other benign genitourinary diseases. Moreover, $UBC^{TM}$ test could be an especially valuable marker for diagnosis of TCC in patients with early TCC of low grade TCC compared to urinary cytology. Therefore, mbined use of $UBC^{TM}$ test in association with cytology is helpful to overcome the limited sensitivity of cytology.

• Fashion, Industry and Education
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• v.15 no.2
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• pp.25-35
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• 2017

In this study, causal relationships of belief-attitude-purchase intention for unfamiliar-branded cosmetics (UBC) were tested based on the theory of reasoned action. Data of 249 consumers who have purchased UBC were submitted to the descriptive statistics, exploratory factor analysis, and regression analysis with SPSS. In results of exploratory analysis, three factors of beliefs on UBC were generated and titled as ingredients, publicity, and subsidiary features. In regression analysis results, ingredient factor affected attitude toward UBC while publicity and subsidiary features did not influence attitude toward UBC. It implies that consumers build their attitude toward brands focusing on ingredients that are core elements of cosmetic products. Attitude toward UBC solely influenced purchase intention while the effect of social acceptance on purchase intention was not found. In conclusion, consumers depend much on ingredients when they purchase UBC so brands newly launched or brands without reputations need to focus more on an excellence in ingredients and special functions of UBC to appeal to consumers when penetrating to the new market.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.40 no.10
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• pp.637-644
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• 2016

The purpose of this study is to understand the characteristics of unburned carbon (UBC) and NOx emissions for pulverized coal when air staging combustion is applied. A two-staged drop tube furnace capable of applying air staging combustion was designed and installed. The combustion of sub-bituminous (Tanito) has been investigated. UBC and the NOx concentration were measured under various temperatures and stoichiometric ratios in unstaged and staged combustion. As a result, UBC decreased and the NOx concentration increased with an increase in stoichiometric ratio and temperature. In particular, the NOx reduction mechanism was activated when the temperature in the fuel rich zone increased. Both UBC and the NOx concentration decreased as the temperature increased in the fuel rich zone. A high NOx reduction effect was obtained, compared to the UBC increase, when the air staging technique was applied.

• Interdisciplinary Bio Central
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• v.4 no.4
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• pp.13.1-13.6
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• 2012

The advanced glycation endproducts receptor (AGER) is a multiligand signal transduction receptor. One of its ligands, S100b molecules activates vascular smooth muscle cells and endothelial cells via its receptor, thus triggering activation of signaling cascades and generation of cytokines and proinflammatory molecules. Ubiquitin-conjugating enzyme Ubc9 is an E2 conjugating enzyme that transfers the activated small ubiquitin-related modifier to protein substrates, and thus it plays a critical role in SUR-Mylation-mediated cellular pathways. Previous studies have shown that both AGE-R and Ubc9 play roles in diverse cellular signaling pathways. However, until recently, little attention has been paid to interactions between AGE-R and Ubc9. In this study, sequence database searches allowed us to identify a potential interaction motif between AGE-R and Ubc9. The subsequent biochemical and molecular biological analysis suggested that there may be specificity in AGE-R and Ubc9 complex signaling in atherosclerosis and cancer cells in a cell-type specific manner. Although the determinant for specificity in AGE-R and Ubc9 complex signaling in cancer cells and atherosclerosis is yet to be determined, this study provides the basis to develop a specific therapeutic application of AGE-R, SURM (small ubiquitin-related modifier)-1, and Ubc9 complex activation pathways in atherosclerosis, diabetes, cancer and inflammatory diseases.

• Journal of the Earthquake Engineering Society of Korea
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• v.4 no.1
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• pp.63-76
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• 2000

구조물-지반 상호작용에서 알려진 것처럼 구조물 지진응답은 구조물하부 지반조거에 따라 영향을 받는데 UBC-97을 포함한 여러내진설계규준에서 지반사태 영향을 반영하고 있다 이 연구에서는 기초크기 기초밑 지반깊이, 입력지진 작용점 및 기초 근입깊이 등의 영향을 살펴보고 깊은 지반 위에 세워진 구조물의 평균응답스펙트럼을 UBC-97 탄성응답스펙트럼과 비교하기 위해 구조물-지반 상호작용을 고려한 지진해석을 가상 3차원 유한요소법과 부구조물법을 이용하여 1952년 Taft와 1940년 El Centro 지진기록을 주파수영역에서 수행하였다 연구결과에 의하면 기초크기는 구조물 응답에 별 영향이 없고 기초저면 지반깊이는 구조물체계의 고유주기와 최대가속도를 변경시켰다 또 입력지진의 합리적 작용점은 기초저면이라는 것이 확인되었으며 깊은 지반위에 놓인 기초의 근입은 저주기영역에서 구조물 응답을 상당히 줄어들게 하였다 한편 30m 깊은 지반위에 세워진 구조물의 평균가속도와 UBC-97 가속도를 비교한 결과 UBC-97 탄성응답스펙트럼에 의한 구조물 내진설계가 안전하지 못할 수도 있으므로 UBC-97 지진계수의 할증이 필요하다.

• BMB Reports
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• v.45 no.11
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• pp.641-646
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• 2012

It has been reported that ubiquitin-conjugating enzyme 9 (Ubc9), the unique enzyme2 in the sumoylation pathway, is up-regulated in many cancers. However, the expression and regulation of UBC9 in glioma remains unknown. In this study, we found that Ubc9 was up-regulated in glioma tissues and cell lines compared to a normal control. UBC9 knockdown by small interfering RNA (siRNA) affected cell proliferation and apoptosis in T98G cells. Further experiments revealed that microRNA (miR)-214 directly targeted the 3' untranslated region (UTR) of UBC9 and that there was an inverse relationship between the expression levels of miR-214 and UBC9 protein in glioma tissues and cells. miR-214 overexpression suppressed the endogenous UBC9 protein and affected T98G cell proliferation. These findings suggest that miR-214 reduction facilitates UBC9 expression and is involved in the regulation of glioma cell proliferation.

• Molecules and Cells
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• v.20 no.3
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• pp.446-451
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• 2005

Diap1 is an essential Drosophila cell death regulator that binds to caspases and inhibits their activity. Reaper, Grim and Hid each antagonize Diap1 by binding to its BIR domain, activating the caspases and eventually causing cell death. Reaper and Hid induce cell death in a Ring-dependent manner by stimulating Diap1 auto-ubiquitination and degradation. It was not clear that how Grim causes the ubiquitination and degradation of Diap1 in Grim-dependent cell death. We found that Grim stimulates poly-ubiquitination of Diap1 in the presence of UbcD1 and that it binds to UbcD1 in a GST pull-down assay, so presumably promoting Diap1 degradation. The possibility that dBruce is another E2 interacting with Diap1 was examined. The UBC domain of dBruce slightly stimulated poly-ubiquitination of Diap1 in Drosophila extracts but not in the reconstitution assay. However Grim did not stimulate Diap1 poly-ubiquitination in the presence of the UBC domain of dBruce. Taken together, these results suggest that Grim stimulates the poly-ubiquitination and presumably degradation of Diap1 in a novel way by binding to UbcD1 but not to the UBC domain of dBruce as an E2.

• The Journal of Engineering Geology
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• v.33 no.1
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• pp.151-167
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• 2023

This study compares the revised method in loose saturated sandy ground where the LNG storage tank will be installed with an evaluation method by one-dimensional effective stress analysis using the UBC3D-PLM model. Various laboratory and field tests were conducted to establish the parameters necessary for evaluation. The revised liquefaction evaluation method using the seismic response analysis result and N value from standard penetration testing evaluated the possibility of liquefaction as high, but assessment using effective stress analysis, which can consider various liquefaction resistance factors, found the site to be somewhat stable against liquefaction. One-dimensional finite element analysis using UBC3D-PLM modeling facilitated easier assessment of stability against liquefaction than the other methods and minimized the area required for reinforcement against liquefaction. In addition, it is expected that two-and three-dimensional numerical analysis considering the foundation of the LNG storage tank can identify the seismic design and behavior when liquefaction occurs.

• Journal of Information Processing Systems
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• v.6 no.3
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• pp.323-334
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• 2010

The broadcasting & telecommunication services in the future will be converged and be serviced on mobile devices. However, the current ICT infrastructure does not fully meet the future demand for those converged, realistic, intelligent, and personalized services. The Korean government is going to establish a high speed next generation network called UBcN (Ultra-Broadband Convergence Network) by 2013. The Korean government has announced a multi-year plan to establish an UBcN network and to discover and stimulate new converged services for an UBcN in January, 2009. The author of this paper has taken part in formulating development plans since the early stages of planning. In this paper, Korea's development plans for the next generation network and their development strategies are analyzed and discussed based on the author's experience. The paper also discusses the expected impacts of the plan for the future ICT industry, and the implications of government-driven development plans.