• Title/Summary/Keyword: U6

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Utility of Serum and Urine uPAR Levels for Diagnosis of Breast Cancer

  • Soydinc, Hilal Oguz;Duranyildiz, Derya;Guney, Nese;Derin, Duygu;Yasasever, Vildan
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.6
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    • pp.2887-2889
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    • 2012
  • Malignant tumors have a capacity to degrade the extracellular matrix by controlled proteolysis. One system involved in these processes is the urokinase-type plasminogen activator (uPA) system. uPAR levels are elevated in tumors from several types of cancer. Our study was planned to investigate serum and urine levels of uPAR in breast cancer patients (n=180) and healthy controls (n=60) by ELISA. Serum (p<0.001) and urine (p<0.001) uPAR values in the patients were both significantly elevated. High serum and urine levels of uPAR can be used as diagnostic tools in lymph node positive patients.

MULTIPLICITY OF NONTRIVIAL SOLUTIONS TO PERTURBED SCHRÖDINGER SYSTEM WITH MAGNETIC FIELDS

  • Zhang, Huixing;Liu, Wenbin
    • Bulletin of the Korean Mathematical Society
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    • v.49 no.6
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    • pp.1311-1326
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    • 2012
  • We are concerned with the multiplicity of semiclassical solutions of the following Schr$\ddot{o}$dinger system involving critical nonlinearity and magnetic fields $$\{-({\varepsilon}{\nabla}+iA(x))^2u+V(x)u=H_u(u,v)+K(x)|u|^{2*-2}u,\;x{\in}\mathbb{R}^N,\\-({\varepsilon}{\nabla}+iB(x))^2v+V(x)v=H_v(u,v)+K(x)|v|^{2*-2}v,\;x{\in}\mathbb{R}^N,$$ where $2^*=2N/(N-2)$ is the Sobolev critical exponent and $i$ is the imaginary unit. Under proper conditions, we prove the existence and multiplicity of the nontrivial solutions to the perturbed system.

Girder Section of Continuous Bridges Spliced by Partial Post-Tensioning (부분 포스트텐션닝 방법에 의해 연속화된 교량의 주형단면)

  • 이환우;곽효경;송영용
    • Journal of the Korea Concrete Institute
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    • v.12 no.6
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    • pp.43-50
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    • 2000
  • In this paper, a new splicing method was applied to design the girder section of bridges with the span length of 25m, 30m, 35m, 40m and 45m. A U-type precast prestressed section was also determined for each bridge. Additionally, the sectional area, beam depth and Guyon's efficiency factor of the spliced U-type sections in each span were analyzed in comparison with the present I-type PSC bridges. As a result, in spite of an increase of 31%∼50% in the sectional areas compared with the I-type precast girders, the spliced U-type the beam depth of the spliced U-type girder was designed as 2,050 mm compared with the I-type precast girder of 2,600mm in a 40m span bridge. The sectional efficiency factors of the spliced U-type sections were analyzed as 0.76∼0.99. It shows that the spliced U-type sections ar of a superior structural efficiency in contrast to the average sectional efficiency factor of 0.66 value in the I-type girders.

Introduction of U.S. Professional Engineer System and Examination (미국의 기술사 제도와 시험 소개)

  • Ku, Pon-chun
    • Journal of the Korean Professional Engineers Association
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    • v.41 no.6
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    • pp.45-48
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    • 2008
  • Exam administration agreement was signed by the Korean Professional Engineers Association (KPEA) and the National Council of Examiners for Engineering and Surveying (NCEES) at the 2nd National Convention of Professional Engineers on 6 September 2008. Korean engineers can take U.S. Professional Engineer examination under proctor of KPEA in Korea from next April. It helps to broaden for Korean young engineers to have a chance to work and to be recognized as a professional engineer in the U.S. This is a brief introduction of U.S. Professional Engineer system and examination.

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The Pilot Study of the Hepatotoxicity of Aconiti Radix Lateralis Preparata Contained Herbal Medicine in 6 Cases (부자를 포함한 한약처방이 간효소치에 미치는 영향 -임상 6예를 중심으로)

  • 구본수;김태경;한진안;문상관;김영석
    • The Journal of Korean Medicine
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    • v.23 no.1
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    • pp.177-182
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    • 2002
  • It is considered that herbal medicine may also have hepatotoxicity and Aconiti Radix Lateralis Preparata is thought to be the most poisonous. We investigated the changes of aspartate aminotransferase (AST), alanine aminotransferase (ALT) and ${\gamma}-glutamyltranspeptidase{\;}({\gamma}-GT$)$ in 6 cases administrated herbal medicine containing Aconiti Radix Lateralis Preparata and tried to evaluate its influence on liver enzymes. Before administration, the mean values of AST and ALT were $30.5{\pm}12.4${\;}U/L{\;}and{\;}30.7{\pm}22.5{\;}U/L$. After administration, those of AST, ALT and ${\gamma}-GT{\;}were{\;}25.7{\pm}8.7 {\;}U/L,{\;}28{\pm}14.8{\;}U/L{\;}and{\;}34.3{\pm}19.4{\;}U/L$ respectively. Therefore, it is indirectly assured that herbal medicine containing Aconiti Radix Lateralis Preparata didn't influence liver enzymes such as AST, ALT, ${\gamma}-GT$.

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Perinatal and Postnatal Study of LBD-001, a Recombinant Human Interferon $\gamma$, in Rats

  • Cho, Sung-Ig;Lee, Eun-Bang
    • Toxicological Research
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    • v.13 no.1_2
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    • pp.175-182
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    • 1997
  • LBD-001, a recombinant human interferon $\gamma$ produced by genetically engineered yeast as a host system, was intravenously administered to pregnant female rats (Sprague-Dawley) from day 17 of gestation to day 21 of lactation at dose levels.of $0.35 \times 10^6$, $0.69 \times 10^6$, and $1.38 \times 10^6$ I.U./kg/day. In vasopressin-treated group, vasopressin (5 I.U./kg/day) was intravenously injected only for 5 days of perinatal period. (1) No signicant changes by the treatment of LBD-001 were observed in the body weights, food and water consumption, feeding and nurshing behaviors, and the weights of main organs of mother rats. In vasopressin-treated group, no significant changes were observed except the decrease in the food consumption on day 18 of gestation and one case of abnormal offspring with bleeding spots on the skin. (2) No significant changes in the body weights, survival rates, locomotor activity, emotional development. and the motor coordination of offsprings (F1) by the treatment of LBD-001 were observed except the fact that increase of ambulation in the female offsprings of LBD-001 ($0.69 \times 10^6$ or $1.38 \times 10^6$ I.U./kg/day)-treated groups and the increase of rearing in the males of LBD-($1.38 \times 10^6$ I.U./kg/day)-treated group, and the increase of the weight of liver and ovaries in the female offsprings in the LBD-001 ($1.38 \times 10^6$ I.U./kg/day)-treated group were observed. Altogether, the results show that LBD-001 at the dose of $1.38 \times 10^6$ I.U./kg/day or less does not significantly affect the mother rats and their offsprings (F1) except the minor influences when treated during the perinatal and postnatal period.

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Thermal Design and On-Orbit Thermal Analysis of 6U Nano-Satellite High Resolution Video and Image (HiREV) (6U급 초소형 위성 HiREV(High Resolution Video and Image)의 광학 카메라의 열 설계 및 궤도 열 해석)

  • Han-Seop Shin;Hae-Dong Kim
    • Journal of Space Technology and Applications
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    • v.3 no.3
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    • pp.257-279
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    • 2023
  • Korea Aerospace Research Institute has developed 6U Nano-Satellite high resolution video and image (HiREV) for the purpose of developing core technology for deep space exploration. The 6U HiREV Nano-Satellite has a mission of high-resolution image and video for earth observation, and the thermal pointing error between the lens and the camera module can occur due to the high temperature in camera module on mission mode. The thermal pointing error has a large effect on the resolution, so thermal design should solve it because the HiREV optical camera is developed based on commercial products that are the industrial level. So, when it operates in space, the thermal design is needed, because it has the best performance at room temperature. In this paper, three passive thermal designs were performed for the camera mission payload, and the thermal design was proved to be effective by performing on-orbit thermal analysis.

Effects of Undaria Pinnatifida on Serum and Liver Lipids in Rats (미역첨가급식(添加給食)이 흰쥐의 간(肝) 및 혈청(血淸)의 지질농도(脂質濃度)에 미치는 영향(影響))

  • Hahn, Jai-Kum;Koh, Jin-Bog
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.15 no.4
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    • pp.17-23
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    • 1986
  • This study was designed to observe the effect of Undaria Pinnatifida (U. P.) Powder on serum and liver lipids concentration in rats. Adult male rats of Sprague-Dawley strain were divided into four diet groups: one control diet and the other three diets in which U.P. powder was mixed with the control diet at the rate of 1%, 2% and 3% respectively. The results of the above observation were as follows : Serum and liver total lipids in 3% U.P. group were lower an those in control group at the 6th week. There was no difference in serum and liver total cholesterol among the diet groups. Serum HDL-cholesterol and HDL-cholesterol per total cholesterol ratio in 3% U.P. group were higher than those in control group at the 3rd and 6th week. Serum triglyceride in 3% U.P. group was significantly lower than that in control group at the 3rd week. Serum phospholipid in 1% U.P. and 3% U.P. group was significantly lower than that in control group at the 3rd week, but there was no difference among them at the 6th week.

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Screening of Fibrinolytic Activities from Cultured Mushrooms (인공재배 버섯의 혈전분해효소 활성검색)

  • Choi, Han-Seok;Kim, Myung-Kon;Park, Hyo-Suk;Kim, Jae-Sung;Shen, Ming-Hva;Kim, Sung-Jun
    • Korean Journal of Food Science and Technology
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    • v.37 no.6
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    • pp.1039-1041
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    • 2005
  • Fibrinolytic activities of cultured medium and mycelium from 13 selected culturable mushrooms ranged 0.00-0.16 U and 0.00-0.48 U, respectively. Dry cell weight of Armillaria mellea was 6.50g/100mL, 1.9-5.0 fold higher than other tested mushrooms. Among artificially cultured mushroom fruiting bodies tested, fibrinolytic activity was lowest in Hericium erinaceus (0.17 U) and highest in Pleurotus ferulea (0.94 U).

Relationship of the U-Factor and Chemical Structure with Applied Metal and Polymer Material Assembly in Curtain Wall Frame

  • Park, Tongso
    • Korean Journal of Materials Research
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    • v.31 no.8
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    • pp.450-457
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    • 2021
  • From measured thermal conductivity and modeling by simulation, this study suggests that U-factors are highly related to materials used between steel and polymer. The objective and prospective point of this study are to relate the relationship between the U-factor and the thermal conductivity of the materials used. For the characterization, EDX, SEM, a thermal conductive meter, and computer simulation utility are used to analyze the elemental, surface structural properties, and U-factor with a simulation of the used material between steel and polymer. This study set out to divide the curtain wall system that makes up the envelope into an aluminum frame section and entrance frame section and interpret their thermal performance with U-factors. Based on the U-factor thermal analysis results, the target curtain wall system is divided into fix and vent types. The glass is 24 mm double glazing (6 mm common glass +12 mm Argon +6 mm Low E). The same U-factor of 1.45 W/m2·K is applied. The interpretation results show that the U-factor and total U-value of the aluminum frame section are 1.449 and 2.343 W/m2·K, respectively. Meanwhile, those of the entrance frame section are 1.449 and 2.