• 대한본초학회지
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• 제37권6호
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• pp.53-59
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• 2022

Objectives : Cleanser is the most basic tools used in daily skin care. I made a cold process soap using Castanea crenata inner shell (CCIS). I'd like to study the effect of face wash using CCIS cold process (CP) soap on the skin. Methods : The same water and towel were used at the same place in order to examine the skin change state immediately before and after washing face. The skin test was performed before and after 10 minutes washing the face in order to remove these external environmental factors, such as lifestyle, alcohol, tobacco, and stress etc. As a control group, the cases of washing with water and foam cleanser (F/C), which is a popular commercial product, were set. Three cases were compared and analyzed. Results : In the case of water washing, there was a significant decrease in oil (U-zone) but that was not good effect. In the case of F/C and CCIS washing, there were significant decrease in oil (T-zone), pores and pigmentation, but the significance was bigger in CCIS washing. In the case of pores, there was a significant decrease in all three cases. Conclusion : In the case of F/C and CCIS washing, it showed the effect of reducing T-zone oil, pores and pigmentation. But the significance was greater in CCIS case than in F/C case. CCIS cp soap is considered as a form of face wash that is suitable for skin care.

• 대한본초학회지
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• 제38권2호
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• pp.9-16
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• 2023

Objectives : Many people use natural soap instead of commercially available bar type general soap for skin care. They tend to prefer cp (cold process) type soaps that go through a sufficient maturation process in formulation. The purpose of this study was to investigate the efficacy of PCPS (placenta cp soap). Methods : The researcher selected 36 subjects, 28 as the experimental group and 8 as the control group. I asked participants to wash their face twice a day in the morning and evening, and the period was set for 6 weeks. The researcher had the people who were selected as the control group use a commercially available foam cleanser, meanwhile the experimental group use PCPS. They performed a skin test before the start of the test, and the change status was continuously investigated after 2 weeks, 4 weeks, and 6 weeks after using the soap. Results : In the case of U zone oil and pores, there was a significant decrease and in the case of skin tone, there was a significant increase in the group of using PCPS. In T zone oil change, there was no significant effect in both the experimental group and the control group. Conclusion : In the case of PCPS, it is recommended to use it in the effect of reducing the size of pores and increasing skin tone, but it can reduce u-zone oil content.

• 대한한의학회지
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• 제44권2호
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• pp.34-44
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• 2023

Objectives: The purpose of this research was to find out the efficacy of Castanea crenata Inner Shell (CCIS) distilled herbal medicine on the skin by comparing the difference effect between only simple distilled water and the CCIS distilled herbal medicine application after MTS (microneedle therapy system) treatment. Methods: The present author performed once a week and total 4 times of MTS treatment. The treatment time took about 5~10 minutes and the depth of the needle was adjusted according to the participant's skin condition. In the control group, simple distilled water was applied after MTS and in the experimental group, CCIS distilled herbal medicine was applied. One week after each treatment, the change of skin condition was measured. Two weeks after the end of the clinical trial, the skin condition was checked again. Results: In the case of the test group, there was a significant decrease in pore size and there was a significant increase in U-zone oil, skin tone and elasticity. The test group using distilled herbal medicine showed a significant effect on facial skin compared to the control group using only simple distilled water. Conclusion: Distilled herbal medicine showed an effective action on facial skin. In the case of CCIS distilled herbal medicine, it was found to have a significant effect on U-zone oil content, skin tone, pores, and skin elasticity.

• 대한본초학회지
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• 제38권2호
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• pp.35-41
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• 2023

Objectives : Washing face is the first step in skin beauty and health. I wanted to study the cleansing effect by using Placenta cp (cold process) soap. The skin condition is greatly influenced by the external environment such as lifestyle, drinking, smoking, and stress etc. I tried to measure the skin change state without environmental factors. Methods : In order to examine the effect before and after washing face under the same conditions, the same water and towel were used in the same place. The skin test was performed before and 10 minutes after washing. As a control group, a case of washing with water and foam cleanser. I compared and analyzed three cases: water washing, F/C (foam cleanser) washing, and Placenta cp soap washing. Results : In the case of water washing, it was significantly reduced in pores and increased in facial temperature. In the case of F/C washing, the facial temperature was significantly increased, but the decrease in moisture. In the case of washing with Placenta cp soap, significant reductions in T-zone and U-zone oil content, reduction in pore size, and increase in facial skin temperature were observed. Conclusion : In the case of Placenta cp soap, it is thought to be suitable for oily skin type, because of significant decrease in T-zone and U-zone oil content. It is thought to have the effect of increasing blood circulation in the facial skin and to reduce pores for oily skin types.

• 패션비즈니스
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• 제25권4호
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• pp.1-13
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• 2021

As interest in skin care increases, this study aims to contribute to the development of the beauty self-care market by providing basic data through the measurement of the oil and moisture skin condition of women in their 20s and 30s. The study was conducted from November 27, 2020 to January 31, 2021, with 20 women in their 20s and 30s divided into 4 groups, A~D, by age, 5 per group. Skin measurements were taken four times at 4 hour intervals at 0H, 4H, 8H, and 12H based on the first measurement that was taken within 30 minutes after waking up, and the oil and moisture indices were observed over time. As a result, both T and U zones showed significant differences in moisture levels over time, with no difference between groups for both T and U zones. Moisture decreased the most between 0H to 4H, and moisture changed the least between 4H to 8H. Changes in moisture increased the similar at 0H and 12H. The oil condition changed more irregularly compared to moisture over time, but all groups showed lower oil content in the U-zone compared to the T-zone. Overall, the facial oil and moisture conditions of women in their 20s and 30s changed over time, indicating that the skin changes in real time. The fact that the skin data, which was measured in the primary activity living environment, can be used as basic research data in the beauty self-care market is meaningful.

• 디지털융복합연구
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• 제15권6호
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• pp.545-550
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• 2017

본 연구는 무농약 재배 Pleurotus eringii 추출물을 함유한 화장품의 효능을 평가하여 새로운 천연 화장품 원료를 개발 하고자 실험을 진행하였다. Pleurotus eringii 는 우리나라 경상남도에서 무농약으로 재배된 2016년산을 구입하여 건조한 후 80% EeOH로 상온에서 추출하였다. 추출물의 항산화활성은 DPPH assay와 ROS assay로 평가하여 우수한 효능을 확인하였고, 추출물 5%를 함유한 크림팩을 제조하여 수분, 유분, pH, 색소의 항목을 평가한 결과 T-zone부위의 유, 수분 항목에서 통계적으로 유의미한 차이를 보였으며, U-zone 유분변화, pH, 색소 등의 항목에서는 통계적으로 유의한 차이가 없었다. 그러나 실험군의 피부변화가 대조군에 비해 모든 항목에서 우수한 효능을 보여 Pleurotus eringii 추출물의 화장품 원료로서의 효능을 확인 할 수 있었고, 향 후 농도별, 추출조건 및 재배조건을 고려한다면 더욱 향상된 화장품 소재로서의 가능성을 평가 받을 수 있을 것으로 판단된다.

• 대한한의학회지
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• 제40권2호
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• pp.133-141
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• 2019

Objectives: The condition of the skin is greatly influenced by seasonal changes. We wanted to know the seasonal change of skin condition and to find out the difference in the efficacy of Seoshiokyongsan (SSOOS) CP soap in spring and autumn. We are to help people who use soap to make a wise choice in choosing a cleanser according to the season. Methods: To investigate the seasonal skin condition, this experiment was conducted to examine the skin condition of spring and autumn in 20 students at A university. To compare the seasonal efficacy of Seosiokyongsan (SSOOS) CP soap, we had skin test 10 students in spring and autumn. We made herbal fermented soaps using SSOOS and distributed them to experiment participants. We let them wash their face in the morning and evening for 6 weeks using herbal fermented soap. Prior to the experiment, their skin condition was checked and assessed using A-ONE Smart One-Click Automatic Facial Diagnosis System three times at 3-week intervals. After the experiment, the changes of skin were measured and analyzed through facial analysis test. Results: In spring and autumn, the oil of T zone and U zone was significantly less and the water content was significantly higher in autumn than in spring. In the case of using the SSOOS CP soap, water content increased and oil content decreased in spring, oil content and elasticity increased in autumn. Conclusion: There is a difference in the skin condition according to the season and SSOOS CP soap showed difference in efficacy in spring and autumn. So we should pay attention to seasonal soap selection.

• 한국항공운항학회지
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• 제19권3호
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• pp.43-53
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• 2011

It is well known some Foreign aircraft used to fly INCHEON FIR(Flight Information Region), especially the island of IEODO without a flight plan, even though foreign aircraft is subject to submitting a flight plan to Flight Information Center(FIC) before its flight. IEODO is a sunken rock 4.6m beneath the sea level, 149km away from Marado. Facing the Yangtze river's sea entrance horizontally and military zones of Korea and China vertically, IEODO is a very important place for national security of North East Asia because it is located at the boundary between China East Sea and Yellow Sea of South Korea. Moreover, JDZ(the 7th mine lot) is just 77NM from IEODO, which possesses natural gas eight times bigger than the gulf region and oil 4.5 times bigger than that of the U.S. In addition, INCHEON FIR, managed by MLTM(Air Traffic Control Center) and Japanese Self-Defense Force's JADIZ(Japanese Air Defense Identification Zone) are overlapping on IEODO whose air space is very complex. This paper focuses on air space, FIR, ADIZ(Air Defense Identification Zone) and related airspace system and suggests strategic implications of how to prevent foreign aircraft from invading INCHEON FIR without permission and of how to utilize the airspace efficiently.

• Journal of Microbiology and Biotechnology
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• 제10권6호
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• pp.764-769
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• 2000

The lipase gene(lip) from Bacillus stearothermophilus was recombined in vitro by utilizing the DNA shuffling technique. After four rounds of shuffling, transformation, and screening based on the initial rate of clear zone formation on a tricaprylin plate, a clone (M10) was isolated, the cell extract of which showed about 2.8-fold increased lipase activity. The DNA sequence of the mutant lipase gene (m10) showed 3 base changes, resulting in two cryptic mutations and one amino acid substitution: S113($AGC{\rightarrow}AGT$), L252 ($TTG{\rightarrow}TTA$), and G275E ($GGA{\rightarrow}GAA$). SDS-PAGE analysis revealed that the increased enzyme activity observed in M10 was partly caused by high expression of the m10 lipase gene. The amount of the expressed G275E lipase was estimated to comprise as much as 41% of the total soluble proteins of the cell. The maximum velocity ($V_{max}$) of the purified mutant enzyme for the hydrolysis of olive oil was measured to be 3,200 U/mg, which was 10% higher than that of the parental (WT) lipase (2,900 U/mg). Its optimum temperature for the hydrolysis of olive oil was $68^{\circ}C$ and it showed a typical $Ca^{2+}$-dependent thermostability, properties fo which were the same as those of the WT lipase. However, the mutant enzyme exhibited a high enantiospecificity towards (S)-naproxen compared with the WT lipase. In addition, it showed increased hydrolytic activity towards triolein, tricaprin, tricaprylin, and tricaproin.

• 대한본초학회지
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• 제34권6호
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• pp.125-130
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• 2019

Objective : We have reported the effects of Seosiokyongsan (SSOOS) cp soap on increasing skin moisture, decreasing pore size, and reducing acne symptoms on previous studies. But in the case of SSOOS soap, many soap bases were used in the making process. So we could not determine whether the above test results were the effect of soap bases or SSOOS herb medicine. Therefore, We conducted this clinical test to find out the effect of SSOOS itself. Methods : We made two kinds of soap. One type was made of cp soap using only soap bases and gave them to 10 subjects. The other type was cp soap made by adding SSOOS to the soap base and gave them to 25 subjects. The other 10 subjects did not limit the soap. Subjects were asked to wash their face with soap in the morning and evening for six weeks. The test was conducted three times and the results were compared and analyzed. Results : In the test group using the SSOOS soap, the oil in the U zone was significantly decreased and the moisture was significantly increased compared to other two control groups. Pores size and pigmentation were decreased but not significant. There was a significant increase in moisture in the soap base group, but that was a slight increase compared to SSOOS soap. There was no significant results in the without soap control group. Conclusion : SSOOS soap was found to have a significant effect on facial skin as cleansing products.