• 한국수산과학회지
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• 제14권2호
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• pp.59-65
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• 1981

빛에 대한 어류의 행동을 조사하기 위하여, 볼낙Sebastes inermis과 두툽상어 Scyliorhinus torazame에 빛의 세기가 서로 다른 여섯 가지 백색인공광선으로 광자극을 주어, 그에 대한 반응을 주간과 야간으로 구분 조사한 결과는 다음과 같다. 1. 광자극에 대한 수조내의 구간별 분부는 두 어종이 모두 양단구간에 많이 모여 분부곡선은 대체로 U자형이 되었으나, 어종에 따라 그 형태의 차이가 심했다. 2. 볼낙은 어떤 수중조도 하에서도 광원으로부터 멀리 밀어진 곳에 많이 모이는 경향을 나타냈으며, 주야간에 비슷하였다. 두툽상어는 광원으로부터 멀리 떨어진 곳에 다소 많이 모였으나 구간별 분부차가 적었으며 주야간에 다소의 차가 있었다. 3. 집어율이 최대가 되는 수중조도(적정조도)는 볼낙이 주간에 16.61ux($10.6\sim24.5lux$), 야간에 0.7 lux($0.5\sim1.1lux$)로서 주간에 더 높았다. 두툽상어는 주간에 1.9 lux ($1.2\sim2.9lux$), 야간에 16.61ux ($10.6\sim24.5lux$)로서 야간에 더 높았다. 4. 조명시간에 따른 집어율은 볼낙의 경우 조명시간 중 집어율이 일정한 증감추세를 보이지 않고 불안정하게 변동했으며, 주간보다 야간에 그 변화가 컸다. 두툽상어는 조명시간 중 집어율이 거의 일정하였으며, 주야간의 차이가 뚜렷하지 않았다.

• 무역상무연구
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• 제77권
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• pp.239-258
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• 2018

The purpose of this study is to examine the legal standards of agreements on the origin of liability and the relevant laws in Korea, to suggest implications for custom authorities and traders wishing to benefit from preferential tariff via FTA, citing the excluded cases of related FTA preferences (court cases and administrative judgments). In order to examine the provisions related to supporting evidence of the origin of liability in FTA, we examined FTAs agreed between Korea and EU, EFTA, ASEAN, U.S., and India relevant to FTA Special Customs Act, court cases and administrative judgements. If verifying the origin to protect the fair trade order impedes to promote utilizing FTA, solutions will need to be suggested. If FTA preference is exempted due to verifying the origin by the import customs authorities, the importer shall pay the income tax calculated in accordance with the general tax rate. This is because the certificate of origin confirmed during verification process is different from the actual origin. In most agreements, the exporter (the producer) shall issue the certificate of origin and since the importer has no other option than obtaining the certificate of origin from the exporter, it may face consequences such as declined credibility from the custom authorities in addition to being disqualified for FTA preferential, if the certificate of origin received from the exporter has flaws. On the other hand, the exporter cannot help but being punished by the customs authorities due to issuing defective origin certificates, but it doesn't have conventionary liabilities for damages incurred to the importer. As a result, importers are forced to pursue legal proceedings to claim damages to exporters or to give up FTA preference. As FTA is increasingly utilized, the number and amount of origin verification in Korea has continuously been increasing while administrative judgements indicates other FTA exporters doesn't seem to gain any support in utilizing FTA like Korea does. It has been 8 years since full-scale supports in FTA launched and now is the time to introduce more efficient and intensive FTA support system In this regard, it is desirable to conduct comprehensive verification on export Next, an institutions that assures FTA-based exports should be established in order to compensate the importer's damages that may occur from disqualified certificate of origin issued by the exporter.

• 대한의생명과학회지
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• 제12권3호
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• pp.153-160
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• 2006

Human colon cancer is the second most fatal disease among a variety of cancers to cause cancer death in U.S.A. and its incidence rate is currently increased in Korea. Recently, many studies have been being progressed on the efficacy of diverse combination treatments. But results of these studies in vitro were not similar those in vivo. This study compared the anticancer reactions between each use of arsenic trioxide and taxol against human colon cancer HT-29 cell line and combined use of two drugs. And these results compared with the results of HT-29 spheroid cells having similar characteristics to the solid tumor in vivo. The spheroid of HT-29 cells was formed by using a multicellular spheroid system and the result was observed through electron microscopy. In vitro cytotoxicity of each use of arsenic trioxide and taxol was evaluated in HT-29 monolayer cells. The $IC_{50}$ value for arsenic trioxide was to be $33{\mu}M$ and taxol was to be 18nM. The result treated with the combination of taxol and arsenic trioxide decreased the cytotoxicity on the HT-29 monolayer cells. The spheroid cells represented higher resistance against drugs than the monolayer cells. I demonstrated DNA fragmentation after incubation with concentrations more than $10{\mu}M$ arsenic trioxide and 100nM taxol for 48h, on the monolayer cells. But the results of HT-29 cell line treated with the combination of taxol and arsenic trioxide was the same as the outcome of control samples that were not treated with any drug. And I don't demonstrated DNA fragmentation on the spheroid cells. These results suggest that apoptosis was not induced in the use of the combination can be thought as that arsenic trioxide might work as an antagonist to inhibit a taxol mechanism to induce apoptosis. And the spheroid cells represented higher resistance against drugs than the monolayer cells.

• Toxicological Research
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• 제15권1호
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• pp.79-87
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• 1999

To know the stress response and antioxidative effect of sulfur containing compounds, we observed the expression of the stress protein (heat shock protein; inducible protein) from mouse tissues and evaluated the protective effects to hydroxyl radical in mouse brain cell culture. Cysteine, methionine or sodium sulfide was fed by oral administration of 1 ml/per 6hr/three times with 1 mM, 2mM or 3mM to mouse, respectively. After that, the stress proteins were extracted from mouse tissues and analyzed the features of expression. The stress proteins by sulfur containing compounds were showed different aspects in the kinds and concentrations of their compounds, and in the tissues of mouse. In the liver, the stress proteins were appeared at different time on the concentration of sulfur containing compounds and had less than 20 KDa as small molecules. In general, the molecular weights of stress protein in liver, the stress proteins were appeared at different time on the concentration of sulfur containing compounds and had less than 20 KDa as small molecules. In general, the molecular weights of stress protein in the spleen were evaluated from 32KDa to 50KDA, and the induced times were relatively late at high concentration of cysteine, early at low concentration of methionine or sodium sulfide. The stress proteins in mouse muscle were detected mostly between 24hr after treatment of sulfur containing compounds. Their molecular weights were 15~24KDa. In the antioxidative effects of sulfur containing compounds to hydroxyl radical, cell viabilities were measured by 63.2% at 10 $\mu\textrm{M}$, 65.5% at 50 $\mu\textrm{M}$, 68.6% at 100 $\mu\textrm{M}$, 78.3% at 150 $\mu\textrm{M}$, or 83.0% at 200 $\mu\textrm{M}$ of cysteine, respectively. At addition of methionine, the cell viabilities were assessed as 58.1% at 10 $\mu\textrm{M}$, 62.8% at 50 $\mu\textrm{M}$, 75.7% at 100 $\mu\textrm{M}$, 78.6% at 150 $\mu\textrm{M}$, and 79.2% at 200 $\mu\textrm{M}$ after 4hrs exposure with 20mU/ml glucose oxidase (GO) system, while the numbers of live cells to hydroxyl radicals in treatment of sodium sulfide were showed 48.6% at 10 $\mu\textrm{M}$, 54.8% at 100 $\mu\textrm{M}$, 51.8% at 150 $\mu\textrm{M}$, and 51.6% at 200 $\mu\textrm{M}$ in the neuronal cells. In the inhibitory effects on the proliferation of tumor cells, percentages of dead cells of the CT-26 or HeLa cell were generally less than 30% even 48hr after addition of sulfur containing compounds. Conclusively, the results of these experiments indicate that stress protein by sulfur containing compounds can be used as physiological indicator for animal nutrition and for environment, and also that cysteine and methionine can play critical roles as an antioxidant.

• 생태와환경
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• 제34권3호통권95호
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• pp.206-214
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• 2001

1998년부터 2000년까지 겨울 결빙기를 제외한 청초호의 수질 및 영양상태의 판정결과 부영양화가 심각한 것으로 조사되었다. 투명도는 0.4${\sim}$1.3 m로 비교적 낮은 값을 보였으며, COD농포는 전 조사지점에서 $3.0{\pm}1.0\;mgO_2/L$이었다. 염분은 $29.3{\pm}5.5\;ppt$로 매우 높았으며, 수심 약 0.5${\sim}$l.5 m에서 염분에 의한 화학성층(chemocline)이 형성되어 심층에 산소공급이 제한되었다. 또한 표층보다 심층수의 수온이 높은 수온역전현상이 관찰되기도 하였다. 표층수의 총인은 0.048${\sim}$0.253 mgP/L, 총질소는 0.9${\sim}$2.4 mgN/L의 범위로 나타났으며, 청초호에서의 TN/TP 비는 대체적으로 20 이하로 질소가 수중 생물의 성장과 생성에 제한 요소로 작용할수도 있음을 시사하였다. 그러나 일반적으로 인과 질소의 농도가 높게 유지되어 총질소와 총인의 비로서 제한 요소를 파악하는 것은 무리가 따르는 것으로 판단된다. 유입수가 유입되는 정점 1보다는 해수의 영향이 많은 연안으로 갈수록 점차 TN/TP비가 감소하여 해수의 영향이 클수록 인함량에 대한 질소함량비가 상대적으로 감소하는 것으로 사료된다. 조사기간 식물플랑크톤의 경우는 연중 녹조류인 Microspora sp.가 우점하였으며, 식물플랑크톤에의한 Chl. a값은 매년 감소하는 반면 부유물질의 농도는 점차 증가하여 무기현탁물의 부유물질에 대한 기여도가 점차 증가하고 있음을 알 수 있다. 청초호의 엽록소 a농도는 각 정점 평균 $14.0{\pm}25.0\;mg/m^3$으로 나타나 U.S.EPA 기준으로 볼 때 부영양호로 분류되며, 여름 성장기엽록소 a, 투명도,및 총인의 평균치를 이용한 부영양화도지수 (TSI)도 평균 59${\sim}$77로 부영양 상태로 나타났다.

• Membrane and Water Treatment
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• 제6권5호
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• pp.365-378
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• 2015

Herein, the preparation of anion exchange membrane (AEM) from brominated poly(2,6-dimethyl 1,6-phenylene oxide) BPPO and dimethylaniline (DMA) by phase-inversion process is reported. Anion exchange membranes (AEMs) are prepared by varying the DMA contents. Prepared AEMs show high thermal stability, water uptake (WR) around 202% to 226%, dimensional change ratios of 1.5% to 2.6% and ion exchange capacities (IECs) of 0.34 mmol/g to 0.82 mmol/g with contact angle of $59.18^{\circ}$ to $65.15^{\circ}$. These membranes are porous in nature as confirmed by SEM observation. The porous property of membranes are important as it could reduce the resistance of transportation of ions across the membranes. They have been used in diffusion dialysis (DD) process for recovery of hydrochloric acid (HCl) from the mixture of HCl and ferrous chloride ($FeCl_2$). Presence of $-N+(CH_3)_2C_6H_5Br^-$ as a functional group in membrane matrix facilitates its applications in DD process. The dialysis coefficients of hydrochloric acid ($U_H$) of the membranes are in range of 0.0016 m/h to 0.14 m/h and the separation factors (S) are in range of 2.09 to 7.32 in the $HCl/FeCl_2$ system at room temperature. The porous membrane structure and presence of amine functional group are responsible for the mechanism of diffusion dialysis (DD).

• Asian Pacific Journal of Cancer Prevention
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• 제17권3호
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• pp.1293-1297
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• 2016

Cholangiocarcinoma (CCA) is a serious problem in Thailand, particularly in the northeastern and northern regions. Database of population at risk are need required for monitoring, surveillance, home health care, and home visit. Therefore, this study aimed to develop a geographic information system (GIS) database and Google map of the population at risk of CCA in Mueang Yang district, Nakhon Ratchasima province, northeastern Thailand during June to October 2015. Populations at risk were screened using the Korat CCA verbal screening test (KCVST). Software included Microsoft Excel, ArcGIS, and Google Maps. The secondary data included the point of villages, sub-district boundaries, district boundaries, point of hospital in Mueang Yang district, used for created the spatial databese. The populations at risk for CCA and opisthorchiasis were used to create an arttribute database. Data were tranfered to WGS84 UTM ZONE 48. After the conversion, all of the data were imported into Google Earth using online web pages www.earthpoint.us. Some 222 from a 4,800 population at risk for CCA constituted a high risk group. Geo-visual display available at following www.google.com/maps/d/u/0/edit?mid=zPxtcHv_iDLo.kvPpxl5mAs90&hl=th. Geo-visual display 5 layers including: layer 1, village location and number of the population at risk for CCA; layer 2, sub-district health promotion hospital in Mueang Yang district and number of opisthorchiasis; layer 3, sub-district district and the number of population at risk for CCA; layer 4, district hospital and the number of population at risk for CCA and number of opisthorchiasis; and layer 5, district and the number of population at risk for CCA and number of opisthorchiasis. This GIS database and Google map production process is suitable for further monitoring, surveillance, and home health care for CCA sufferers.

• 디지털콘텐츠학회 논문지
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• 제13권3호
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• pp.393-399
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• 2012

학생들이 다른 언어를 배우고 익히도록 동기부여를 하기 위해 기발한 독창성과 새로운 기술을 필요로 할 것이다. 멀티미디어를 이용하면 수업과 과제를 모든 학생들에게 흥미롭게 해줄 것 이다. 그들에게 관심이 있는 스마트 폰의 사용과, 노트북과 무선 인터넷의 사용으로 학생들은 그들의 언어 기술을 실제로 어디에서나 공부할 수 있을 것 이다. 예를들어 팟캐스트, 인터넷망을 통해 다양한 콘텐츠를 제공하는 서비스 Podcasts 도구 방법 등을 통해 ESL(English as a Second Language) 학습이 매우 용이하게 되었다. 즉 이러한 멀티미디어 tools를 이용한 외국어 듣기 연습 서비스 등 다양한 교수 학습방법 개발이 필요하다. 효율적인 영어 교육을 위한 도입된 이러한 여러 멀티미디어 기기의 사용은 여러 가지 독특한 장점을 가지고 있다. 본 연구에서 영어 교육을 최대화하기 위해 멀티미디어의 특징과 그 활용에 대해 연구하고자 한다. 디지털교과서 및 영어 수업을 위한 멀티미디어 콘텐츠 도구 활용, 인터넷 방송은 물론 원격화상 수업, 사이버 학습 등 1:1 영상 교육을 이용한 유비쿼터스 학습 환경을 제시하고자 한다. 더 나아가 최첨단 u-러닝 기기의 체험을 통해 미래 교육 변화를 조망하고 또한 다양한 수업기기와 변화된 수업시스템 모델을 통해 영어 교육의 새로운 방향을 제시하고자 한다.

• 자원환경지질
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• 제30권1호
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• pp.35-49
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• 1997

The coal formation of the Deokpyeong area are interbedded along metapelites of the Ogcheon Supergroup, which are composed mainly of graphite, quartz, muscovite and associated with small amounts of biotite, chlorite, pyrite and barite. The ratios of $SiO_2/Al_2O_3$, $Al_2O_3/Na_2O$ and $K_2O/Na_2O$ of the coaly metapelite are variable and wide range from 1.80 to 10.21, from 27.8 to 388.8 and from 7.6 to 61.8, respectively. These coal formation were deposited in basin of marine environments, and the REE of these rocks are not influenced with metamorphism and hydrothermal alterations on the basis of $Al_2O_3$ versus La, La against Ce, the ratios of La/Ce (0.19 to 0.99) and Th/U (0.02 to 4.75). These rocks also show much variation in $La_N/Yb_N$ (1.19 to 22.89), Th/Yb (0.14 to 21.43) and La/Th (0.44 to 13.67), and their origin is explained by derivation from a mixture of sedimentary and igneous rocks. The wide range in trace and REE element characteristics as Co/Th (0.12 to 2.78), La/Sc (0.33 to 10.18), Sc/Th (0.57 to 5.73), V/Ni (8 to 2347), Cr/V (0.02 to 0.67) and Ni/Co (1.56 to 32.95) of these coaly metapelites argues for inefficient mixing of the various source lithologies during sedimentation. Deep to pale green barium-vanadium muscovites (vanadium-oellacherite) have been found in this coal formations. Modes of occurrence and grain size of muscovite are heterogeneous, but most of the barium and vanadium-bearing muscovites occur along the boundaries between graphite and quartz grains, ranging from 200 to $350{\mu}m$ in length and from 40 to $60{\mu}m$ in width. Results of X-ray diffraction data of the minerals characterized to be monoclinic system with $a=5.249{\AA}$, $b=8.939{\AA}$, $c=20.924{\AA}$ and ${\beta}=95.894^{\circ}$. Representative chemical formula of the muscovite was $(Na_{0.09}K_{1.44}Ba_{0.46})(Al_{2.75}Ti_{0.07}V_{0.56}Fe_{0.08}Mg_{0.50})(Si_{6.12}Al_{1.88})O_{22}$. The V possibly substitute octahedral Al, and the Ba is coupled substitution of $K^+Si^{4+}=Ba^{2+}Na^+Ca^{2+}$, which compositional ranges of V and Ba are from 0.42 to 0.69 and from 0.34 to 0.56 based on $O_{22}$, respectively. Formation mechanism of the barium-vanadium muscovites in the coaly metapelite is shown that the formed by high pressure and temperature from regional metamorphism origanated during diagenesis at the interface between a basinal brine and organic matter.

• 자원환경지질
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• 제40권1호
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• pp.67-85
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• 2007

제주도 동남부의 전기비저항 구조 및 지하수 분포 형태를 조사하기 위해 제주도 중산간에서 남동방향으로 해안 지역을 횡단하는 두 측선에 대해 인공송신원 자기지전류탐사를 수행하였다. 측점들이 위치한 지질학적 상황을 고려하여 세 종류의 일차원 역산 기법을 도입하였고, 해석의 신뢰성 향상을 위해 각 역산 결과를 비교, 분석하였다. 이 과정으로부터 도출된 제주 동남부의 개략적인 전기비저항 구조는 고비저항-저비저항-보다 저비저항을 갖는 3층 구조였다. 역산 결과와 측점 부근의 심부 시추 자료의 비교를 통해 제주도 동남부의 각 층별 암상이 개략적으로 추정되었다: 지질학적 층서의 관점에서 제 1층과 2층은 두께 100-250m의 현무암층에, 제 3층은 서귀포층 및 U층에 대응하는데, 서귀포층의 두께는 조사심도가 충분히 깊지 않고 서귀포층과 U층의 전기비저항 차이가 작기 때문에 추정할 수 없었다. 그러나 주대수층과 밀접하게 관련 있는 서귀포층은 제주도 동남부 지역의 경우 중산간 지역부터 해안 지역까지 뚜렷한 공간적 연속성을 보여주었다.