• Korean Journal of Ecology and Environment
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• v.38 no.3 s.113
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• pp.352-360
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• 2005

Acheilognathus signifer is distributed widely in high density in the Naechon-stream. The order of this-stream was 2 ${\sim}$ 4 and the water width is wide but the depth is relatively shallow and the sinuosity is 1.83, which indicates a meandering stream. The water width/stream width ratio is 1.59, which suggests moderate entrenchment. Naechon-stream was classed as B type by Rosgen (1995). The natural habitat of A. signifer is a slow flow velocity pool, like a backwater pool, which is made up of piled up boulders that restricts the flow of water. The stream bed is made up of boulders and sands that enable the spawning host to inhabit. A. signifer selects a microhabitat where the boulders furnish hiding places. The Habitat of A. signifer is strongly affected by the existence or not there of U. douglasiae sinuolatus. After hatching from the mussel, A. signifer inhabits the surface of the water. It then moves to the low layer once it acquires swimming ability. While A. signifer inhabits the river in summer, A. signifer moves to the deeper layers in winter, where there are the refuge like rocks and boulders. In spring A. signifer moves from the deep water to the river line where the mussels reside.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.9
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• pp.3785-3792
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• 2015

The CCAAT/enhancer-binding protein-alpha (CEBPA) is a transcriptional factor that plays a crucial role in the control of proliferation and differentiation of myeloid precursors. This gene was recognized as the target of genetic alterations and were associated with clinical complexity among AML. We here analyze the frequency and types of CEBPA mutations and polymorphisms in a de novo AML patients from South India and tried to find out associations of these variations with different clinical parameters and the prognostic significance in AML. Study was carried out in 248 de novo AML patients, cytogenetic analysis was performed from the bone marrow samples and was karyotyped. PCR-SSCP analysis and sequencing was performed for the detection of CEBPA gene variations. All the statistical analysis was performed using SPSS 17 (statistical package for social sciences) software. Pearson Chi-square test, Mann-Whitney U test, Kaplan-Meier survival analysis and log rank tests were performed. CEBPA mutations were detected in 18% and CEBPA polymorphisms were detected in 18.9% of AML cases studied. Most of the mutations occured at the C terminal region. Polymorphisms were detected in both N and C terminal region. with most common being, c.584_589dup ACCCGC and c.690G>T. A significant association was not observed for the mutation and polymorphism with respect to clinical and laboratory parameters. Survival advantage was observed for the mutated cases compared to non mutated cases, especially for the normal karyotype groups. Polymorphisms has no effect on the survival pattern of AML patients. CEBPA mutation and polymorphisms were observed with similar frequency and was identified in all the FAB subtypes as well as in cytogenetic risk groups in our study population, but CEBPA mutations alone confer a prognostic value for NK AML patients.

• Journal of the Institute of Electronics Engineers of Korea SP
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• v.44 no.4 s.316
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• pp.17-25
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• 2007

Multilevel inkjet printer employs multiple ink droplets with variable dot size and/or different concentrations intended to preserve high fidelity color reproduction and the appearance of continuous tone. A variety of research efforts on multitoning techniques has progressed toward better image quality. However, banding artifacts appear due to the same dot distributions near the printable output levels. This results in discontinuity and visually unpleasing output, especially at the smooth tone transition region. In this paper, to reduce the banding artifacts, a multitoning method to arrange ink distribution by controlling the blending proportion of adjacent output pixels based on an improved threshold scaling function is proposed. Ink distributions across the banding regions are changed according to two factors of the threshold scaling function because these factors handle the blending point of adjacent output pixel. Therefore, 8 observers, subjectively investigated ink distributions around the printable output levels for a set of the improved threshold scaling function. For a threshold scaling function with the specific factor values, we can achieve smoother visual transition. In the experiment, the proposed method showed a reduction of banding artifacts in both u-ay and color image and represented better Performance of color reproduction.

• Journal of Sensor Science and Technology
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• v.1 no.1
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• pp.59-66
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• 1992

To develop the highly sensitive TLD radiation sensors, $BaSO_{4}$ : Eu-PTFE TLDs are fabricated by polymerizing the PTFE(polytetrafluoroethylene) with $BaSO_{4}$ : Eu TL phosphors. The $BaSO_{4}$ : Eu TL phosphors having the highest sensitivity of $X/{\gamma}$-rays are obtained by sintering at $1000^{\circ}C$ in $N_{2}$ atmosphere a mixture of $BaSO_{4}$ powder with 1mol% Eu($Eu_{2}O_{3}$), 6mol% $NH_{4}Cl$ and 5mol% $(NH_{4})_{2}SO_{4}$ which were co-precipitated in dilute sulfuric acid and then dried. The activation energy, frequency factor and kinetic order of $BaSO_{4}$ : Eu TL phosphor are 1.17eV, $3.6{\times}10^{11}/sec$ and 1.25, respectively. And the spectral peak of $BaSO_{4}$ : Eu is about 425nm. The optimum TL Phosphor content and thickness of the $BaSO_{4}$ : Eu-PTFE TLD are 40wt% and $105.7mg/cm^{2}$. The optimum polymerization temperature and time for fabrication of $BaSO_{4}$ : Eu-PTFE TLDs are $380^{\circ}C$ and 2 hours in air, respectively. The linear dose range to ${\gamma}$ rays is 0.01-20Gy and fading rate is about 10%/60hours.

• Journal of environmental and Sanitary engineering
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• v.19 no.4 s.54
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• pp.9-18
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• 2004

In this study, the observation data for the yellow sandy dust phenomena from the year 1999 to 2003 at background sites in Korea were collected at Global Atmospheric Observatory at An-Myeon island and its temporal variation were analyzed. The chemical characteristics of the fine particles were also analyzed in order to evaluate sources of the yellow sandy dust particles. The results showed that the monthly average mass concentration of the fine particles was the highest in springtime and the lowest in summertime in general. The magnitude of its variation was also the highest in March in which the occurrence of yellow sandy dust was the most frequent and thus the number of samples was the largest, while the lowest in June through September. The yearly variation of ion components contributions to the total mass concentration of the fine particles was slowly decreasing, showing that $63\%$ in 1999, $59\%$ in 2000 and $56\%$ in 2003. The most prevalent ion components in the fine particles were found to be $NO_3$ and $SO_4^{2-}$, which are known to be source materials of acidic precipitation, and $NH_4^+$, a neutralizing material of the acid precipitation. Relative proportion of metal components in the fine particles was calculated as $14\%$ in average, and their concentrations are in an order of Fe > Al > Na > Ca > Zn > Pb > Cu > Mn > Ni > Cd > Cr > Co > U. The results indicated that main sources of the metals was soil-originated Fe, Al, Ca, and Mg, and the contribution of anthropogenic air Pollution-originated Zn, Pb, Cu, Mn were also high and keep slightly increasing. Statistical analysis showed that the chemical components could be divided into soil-originated group of Mg, Al, Ca, Fe, and Mn and air pollution-originated group of $NO_3$, Zn, Pb, and they are occupying more than $60\%$of all the components in the dusty sand. The results explain that An-Myeon island is more influenced by soil-originated source than ocean-originated one and also the influencing strength of anthropogenic poilution-originated source is less than $50\%$ of that of soil-originated sources. Compared to non-yellow sandy period, the yellow sandy dust period showed that the amounts of soil-originated $Mg^{2+}$ and $Ca^{2+}$ and ocean-originated $Na^+$ and $Cl^-$ were increased to more than double and the metals of Mg, Al, Ca, Fe were also highly increased, while micro metal components such as Pb, Cd, Zn, which have a tendency of concentrating in air, were either decreased or maintained at nearly constant level. In the period of yellow sandy dust, a strong positive correlation was observed between water soluble ions and between metals in terms of its concentration, respectively. Factor analysis showed that the first group being comprised of about $43\%$ of the total inorganic components was affected by soil and they are ions of $Na^+,\;Mg^{2+}\;and\;Ca^{2+}$ and metals of Na, Fe, Mn and Ni. The result also showed that the metals of Mg and Cr were classified as second group and they were also highly affected by soil sources.

• Korean Security Journal
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• no.1
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• pp.283-319
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• 1997

Our society witnesses the rapid progress in the areas of politics, economy, society and culture in the process of national modernization since 1960s, which in turn as a reverse function gets to contract a societic pathology, totally lowering the security level of citizens' lives owing to various violent crimes like hostage commotions and murders with rifles and deadly weapons. what is the main reason for that? That may be partly because the chief police force concentrates on the current situation resulting in the vacuum of the public peace. However, the main reason is that the police fall short of man-power and equipments even if the whole police power were put to use in preventing and quelling the crimes. That is true not only of Korea but also of the advanced countries like the U.S.A., England and Japan. We realize that these advanced countries have higher level of security in every individual's life and property than Korea because their progress of the private guard systems can fill in a vacuum of the shortage of the police power, Therefore, we should without delay internationalize our private guard systems expecting the widely opening of the guard service markets in the age of Uruguay Round. To do this, we need to change our ideas for fostering the policy of the private guard from passive defense ideas into positive aggressive ones. Our police should urgently set up a plan to pursue the orientation of vision that we should dispatch our private guards overseas before foreign guards rush into our markets. Accordingly it goes without saying that the private guard group should distinguish their services from the public services initiating their own theory and strategy of private guard services and also readjust themselves between the public duties and the private services with the study of minimizing the reverse function of the private guard systems. The history criminal justice has always shown that the criminal system progressed at the initiative of the civil factor in case its demand and supply do not make both ends meet. Nevertheless, in the process the power of the government never weakens, rather it is built up in general. In conclusion, the necessity of the build-up of the private guard services must duly be acknowledged by the police as well as by the business which has its unique sphere within the criminal justice instead of as the suplemtary services of the simple the police power on the long-term basis. The purpose of the private guard services can be largely classified into the two categories; first it means the function to prevent the crimes against the citizens and secondly to enhance the national interest as an increasing mammoth business with a worldly competition capacity. The police has an absolute responsibility that they should protect the modem public in general from feeling the crisis of the personal threat, tension, anxiety and nervousness. In short, if we develop the complete private guard system to guarantee the societic atmosphere for all citizens, keep the public peace, and protect all citizens' lives and properties, we will sure enjoy a beautiful land, a wholesome society and a happy life in goodharmony of law and order.

• The Korean Journal of Emergency Medical Services
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• v.13 no.2
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• pp.99-108
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• 2009

Purpose : The purpose of this study is to offer basic data in arranging the improved working environment to Emergency Medical Technicians, by analyzing the influence of job satisfaction in Emergency Medical Technician within hospital upon organizational commitment. Method : This study was carried out targeting 203 Emergency Medical Technicians who are working at hospitals in B Metropolitan City, U Metropolitan City, D Metropolitan City, an d G Province. The data collection was performed from April 1, 2009 to June 10. The statistical processing was used a program of SPSS WIN 12.0 Version. The statistical significance was set to p<.05. Results : 1. In the descriptive statistics of the job satisfaction and the organizational commitment. the whole average for job satisfaction was 3.06 points. The whole average for organizational commitment was 3.05 points. 2. In the difference between job satisfaction and organizational commitment, the group for job satisfaction was indicated to be statistically significant in job-choice motive(F=2.710, p<.05) and turnover propensity(t=.662, p<.001). The group for organizational commitment was indicated to be statistically significant in working department(F=2.871, p<.05), job-choice motive(F=2.944, p<.05), turnover propensity(t=.903, p<.001), and turnover reason(F=3.415, p<.01). 3. In the correlation between job satisfaction and organizational commitment, the job satisfaction showed positive correlation(r=.736, p<.01) with organizational commitment. 4. As for the influence of job-satisfaction factor upon organizational commitment, salary(${\beta}$=.162, t=2.739, p<.01), autonomy(${\beta}$=.372, t=4.633, p<.001), working environment(${\beta}$=.139, t=1.968, p<.05), and organizational needs(${\beta}$=.172, t=2.291, p<.05) were indicated to have significant effect on organizational commitment. Conclusion : The institutional arrangement is considered to be likely to be necessarily made highly for improving social image and enhancing salary and working environment so that Emergency Medical Technician within hospital can be enhanced job satisfaction and organizational commitment.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.10
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• pp.6115-6120
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• 2013

Introduction: Some non-small cell lung cancer (NSCLC) tumor cells are insensitive to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) -based therapy. This study was conducted to examine the effect of embelin on the sensitivity of the A549 NSCLC cell line to TRAIL receptor2 (TRAILR2) monoclonal antibodies and to investigate the potential mechanisms. Materials and Methods: A549 cells were treated with embelin, TRAILR2 mAb or a combination of both. Cell viability was measured using ATPlite assay and apoptosis rates were determined by flow cytometry with AnnexinV-FITC and propidium iodide staining, with the expression levels of proteins analyzed by Western blotting. Results: The cell survival rate of separate treatments with 100 ng/ml TRAILR2 antibody or 25 uM embelin were $81.5{\pm}1.57%$ and $61.7{\pm}2.84%$, respectively. Their combined use markedly decreased cell viability in A549 cells to $28.1{\pm}1.97%$ (P<0.05). The general caspase inhibitor Z-VAD-FMK could inhibit the embelin-enhanced sensitivity of A549 cells to TRAILR2 mAb ($75.97{\pm}3.17%$)(P<0.05). Both flow cytometry and cell morphological analysis showed that embelin was able to increase TRAIL-induced apoptosis in A549 cells. Combined treatment with embelin and TRAILR2 mAb augmented the activation of initiator caspases and effector caspase. In addition, A549 cells showed increasing levels of TRAILR2 protein and decreasing levels of Bcl-2, survivin and c-FLIP following the treatment with embelin+TRAILR2 mAb. Conclusions: Embelin could enhance TRAIL-induced apoptosis in A549 cells. The synergistic effect of the combination treatment might be due to modulation of multiple components in the TRAIL receptor-mediated apoptotic signaling pathway, including TRAILR2, XIAP, survivin, Bcl-2 and c-FLIP.

• Geomechanics and Engineering
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• v.14 no.1
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• pp.99-105
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• 2018

Soils are generally classified as fine-grained or coarse-grained depending on the percentage content of the primary constituents. In reality, soils are actually made up of mixed and composite constituents. Soils primarily classified as fine-grained, still consists of a range of coarse particles as secondary constituents in between 0% to 50%. A laboratory scale model test was conducted to investigate the influence of coarse particles on the physical (e.g., density, water content, and void ratio) and mechanical (e.g., quick undrained shear strength) properties of primarily classified fine-grained cohesive soils. Pure kaolinite clay and sand-mixed kaolinite soil (e.g., sand content: 10%, 20%, and 30%) having various water contents (60%, 65%, and 70%) were preconsolidated at different stress levels (0, 13, 17.5, 22 kPa). The quick undrained shear strength properties were determined using the conventional Static Cone Penetration Test (SCPT) method and the new Fall Cone Test (FCT) method. The corresponding void ratios and densities with respect to the quick undrained shear strength were also observed. Correlations of the physical properties and quick undrained shear strengths derived from the SCPT and FCT were also established. Comparison of results showed a significant relationship between the two methods. From the results of FCT and SCPT, there is a decreasing trend of quick undrained shear strength, strength increase ratio ($S_u/P_o$), and void ratio (e) as the sand content is increased. The quick undrained shear strength generally decreases with increased water content. For the same water content, increasing the sand content resulted to a decrease in quick undrained shear strength due to reduced adhesion, and also, resulted to an increase in density. Similarly, it is observed that the change in density is distinctively noticeable at sand content greater than 20%. However, for sand content lower than 10%, there is minimal change in density with respect to water content. In general, the results showed a decrease in quick undrained shear strength for soils with higher amounts of sand content. Therefore, as the soil adhesion is reduced, the cone penetration resistances of the FCT and SCPT reflects internal friction and density of sand in the total shear strength.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.2
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• pp.999-1003
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• 2014

Objective: To validate the relationship between MACC1 and 6-phosphofructo-2-kinase/fructose 2, 6 bisphosphatase (PFKFB2) expression as well as its clinicopathological features and prognostic significance in hepatocellular carcinoma. Methods: By using immunohistochemistry, we investigated the MACC1 and PFKFB2 protein expression in 60 pairs of hepatocellular carcinoma and corresponding non-tumor tissues. Using the Mann-Whitney U test, the Chi-square test, Kaplan-Meier survival analysis, Cox proportional hazard regression analysis and Spearman analysis, we studied the relationship between MACC1 and PFKFB2 protein expression and postoperative overall survival (OS) of the HCC patients. Results: MACC1 and PFKFB2 positive staining rates were significantly higher in hepatocellular carcinoma than in the corresponding nontumor tissues (P=0.012 and 0.04, respectively). The clinicopathological features evaluation revealed that positive expression of MACC1 was associated with a high Edmondson classification (P=0.007) and advanced TNM stage (P=0.027). Similar findings were evident for PFKFB2 expression (P=0.002 and P=0.027). MACC1 and PFKFB2 positive expression was associated with a lower OS rate (P=0.004 and 0.03, respectively). Kaplan-Meier survival and Cox proportional hazard regression analyses revealed MACC1 positive expression to be a prognostic factor for postoperative OS, but PFKFB was not. Conclusion: Highly expressed MACC1 and PFKFB2 protein were associated with TNM stage, Edmondson-Steier classification and overall survival. MACC1 may affect tumor metabolism partly through expression and phophorylation of PFKFB2.