• Asian Pacific Journal of Cancer Prevention
• /
• v.16 no.18
• /
• pp.8235-8238
• /
• 2016

Background: Lung cancer is one of the most common types of cancer causing high morbidity and mortality worldwide. An increasing incidence of lung cancer has been observed in India. Objectives:To evaluate the clinicpathological profile and haematological abnormalities associated with lung cancer in Bangalore, India. Materials and Methods: This prospective study was carried out over a period of 2 years. A total of 96 newly diagnosed and histopathologically confirmed cases of lung cancer were included in the study. Results: Our lung cancer cases had a male to female ratio of 3:1. Distribution of age varied from 40 to 90 years, with a major contribution in the age group between 61 and 80 years (55.2%). Smoking was the commonest risk factor found in 69.7% of patients. The most frequent symptom was cough (86.4%) followed by loss of weight and appetite (65.6%) and dyspnea (64.5%). The most common radiological presentation was a mass lesion (55%). The most common histopathological type was squamous cell carcinoma (47.9%), followed by adenocarcinoma (28.1%) and small cell carcinoma (12.5%). Distant metastasis at presentation was seen in 53.1% patients. Among the haematological abnormalities, anaemia was seen in 61.4% of patients, leucocytosis in 36.4%, thrombocytosis in 14.5% and eosinophilia in 19.7% of patients. Haematological abnormalities were more commonly seen in non small cell lung cancer. Conclusions: Squamous cell carcinoma was found to be the most common histopathological type and smoking still remains the major risk factor for lung cancer. Haematological abnormalities are frequently observed in lung cancer patients, anaemia being the commonest of all.

• The Journal of the Korea Contents Association
• /
• v.15 no.4
• /
• pp.277-290
• /
• 2015

The main purpose of study is to identify relevance between nature and types of risk factors that delinquent teenagers are exposed and types of methodologies implemented to prevent committing school violence, domestic violence, and suicide or to help recovering from violent activities and suicide attempts. The results show that school dropout has much relevance in risk factors such as probation, lawbreaking, smoking, drinking, runaway, domestic violence victim, and suicidal attempt. Risk rate of school dropout for those teenagers who smoke and drink in the period of runaway is 2.76 times higher than those teenagers who do not smoke or drink. More specifically, drinking increases more risk of school dropout than smoking. Contribution of this study is to identify empirical evidence that calls for comprehensive risk management for delinquent teenagers encompassing home, school, and community rather than focusing on risk itself.

• Korean Journal of Community Nutrition
• /
• v.2 no.4
• /
• pp.539-546
• /
• 1997

This study was designed to investigate factors related to recovery from cerebrovascular accidents(CVA). Medical charts of 100 CVA patients(40 males and 60 females) who had been treated at Bul-Guang hospital in Teagu from June to December 1994 were reviewed to assess their recovery from CVA. Not only types of CVA, blood pressure and serum cholesterol and triglyceride were factors affecting recovery from CVA, but also smoking and drinking status and food preference seemed to be important factors. The percentages of recovered patients were higher in the order of cerebral thrombosis(83.3$\%$), subarachnoid hemorrhage(57.1$\%$), cerebral embolism(50.0$\%$), and cerebral hemorrhage(26.7$\%$). Recovery rates of patients with serum cholesterol below 200mg/dl, 200-239mg/dl, over 240mg/dl were 81.8$\%$, 66.6$\%$, and 16.6$\%$ respectively. Recovery rates of patients with serum triglyceride below 160mg/dl, 160-209mg/dl, and oover 210mg/dl were 84.6%, 72.8$\%$, and 35.7$\%$ respectively. Patients with standard weight recovered better than those with overweight or obesity. Recovery rates of underweight, standard weight, overweight and obesity patients were 73.3$\%$, 85.7$\%$, 45.8$\%$, and 31.6$\%$ respectively. Smoking and drinking seemed to be important factors which inhibited recovery from CVA. Patients preferring spiced foods were recovered better than those preferring salty or pungent foods. (Korean J Community Nutrition 2(4) : 539-546, 1997)

• The Korean Journal of Applied Statistics
• /
• v.27 no.1
• /
• pp.21-30
• /
• 2014

Ordinary survival analysis cannot be applied when a significant fraction of patients may be cured. A cure rate model is the combination of cure fraction and survival model and can be applied to several types of cancer. In this article, the cure rate model is considered in the interval censored data with a cluster effect. A shared frailty model is introduced to characterize the cluster effect and an EM algorithm is used to estimate parameters. A simulation study is done to evaluate the performance of estimates. The proposed approach is applied to the smoking cessation study in which the event of interest is a smoking relapse. Several covariates (including intensive care) are evaluated to be effective for both the occurrence of relapse and the smoke quitting duration.

• Membrane and Water Treatment
• /
• v.5 no.1
• /
• pp.31-40
• /
• 2014

Papermaking tobacco sheet is an important reclaimed process for cigarette making. Traditionally, the pressure driven membrane was often used to isolate the effective compounds from the tobacco sheet extract. However, this method is difficult to remove small ionic compounds. Besides, membrane fouling is a major problem for effective use of these pressure driven membrane technologies. In this study, the electrodialysis process is used to removal the chloride ions and nitrate ions, thus the smoking quality of papermaking tobacco sheet extract can get improved. Three types of electrolytes ($Na_2SO_4$, NaCl and HCl) are chosen to prevent the generation of precipitation. The results indicate that 0.1mol/L HCl at current density of $30mA/cm^2$ is the optimal condition for the electrodialysis process. The removal rates of the Cland $NO{_3}^-$ in tobacco sheet extract are 97% and 98.4%, respectively. The electrodialysis process cost was estimated to be 0.11$/L. Naturally, electrodialysis is not only technological feasible, environmental-friendly and economical-attractive for tobacco extract treatment.

• Asian Pacific Journal of Cancer Prevention
• /
• v.13 no.9
• /
• pp.4639-4643
• /
• 2012

The burden of lung cancer in terms of mortality is the highest among all types of cancers globally. The present study aimed to evaluate lifestyle related habits, clinico-pathological profile and treatment details of lung cancer patients who were registered at Malabar Cancer Centre (MCC), Kerala, during the calendar year 2010. A retrospective evaluation was made from medical records to gather data from 281 registered lung cancer cases in 241 males and 40 females, with a male to female ratio of 6.03: 1. Approximately 89% of the cases were above 50 years of age. Among males about 91% of the cases were smokers and 62% of them had a chronic smoking habit. Adenocarcinomas, squamous cell carcinomas, non-small cell carcinomas and small cell cancers accounted for 10.7, 13.9, 17.0 and 5.7% respectively. Out of 281 cases around 67% were diagnosed with distant metastasis and the remainder had regional lymph node involvement. However, no statistically significant difference was observed for secondary site of tumor according to gender. As majority of the cases reported at MCC were in an advanced stage of the disease, histology of the secondary site from supraclavicular lymph nodes or liver was taken for diagnosis. Initiation of population based screening for early detection of cancer, and primary and secondary prevention strategies for reducing the prevalence of tobacco consumption are high priorities to reduce the lung cancer burden in Kerala.

• Korean Journal of Health Education and Promotion
• /
• v.3 no.1
• /
• pp.83-98
• /
• 2001

Although periodic health examination has been one of the most common practices of preventive medicine, its effect on modification of risk behavior has been seldom assessed. Thus, this study attempted to demonstrate the influence of a health examination on modification of cardiovascular disease related health risk behaviors such as smoking, physical inactivity, and obesity. Data of 893 adults were derived from two types of a popular and highly acclaimed health examination program. With a conceptual model constructed using Persuasive Communication variables, McNemar tests examined Source-Outcome association, hypothesizing that different health examination programs would yield different levels of behavior change in smoking, physical inactivity, and obesity. No significant behavior change was found in any of the two health examination programs. Instead, previously established Receiver-Outcome relationship was reconfirmed by logistic regression modeling where gender was the most prominent predictor of all three behaviors. Men were more likely to be current smokers (OR=0.029), exercisers (OR=2.629), and obese (OR=0.237). The importance of followups after health examination is highly stressed as well as that of gender-specific health education strategies. This study recommends applying the social-ecological approaches in health examination, which emphasizes the support and collaboration at individual, family, organizations, community, and policy level to improve health. Long term and qualitative evaluation of health examination may provide more foundation for increasing the effectiveness of health education and communication in health examinations.

• Journal of Preventive Medicine and Public Health
• /
• v.46 no.4
• /
• pp.165-172
• /
• 2013

A noncommunicable disease (NCD) is a medical condition or disease that is by definition non-infectious and non-transmissible among people. Currently, NCDs are the leading causes of death and disease burden worldwide. The four main types of NCDs, including cardiovascular disease, cancer, chronic lung disease, and diabetes, result in more than 30 million deaths annually. To reduce the burden of NCDs on global health, current public health actions stress the importance of preventing, detecting, and correcting modifiable risk factors; controlling major modifiable risk factors has been shown to effectively reduce NCD mortality. The World Health Organization's World Health Report 2002 identified tobacco use, alcohol consumption, overweight, physical inactivity, high blood pressure, and high cholesterol as the most important risk factors for NCDs. Accordingly, the present report set out to review the prevalence and trends of these modifiable risk factors in the Korean population. Over the past few decades, we observed significant risk factor modifications of improved blood pressure control and decreased smoking rate. However, hypertension and cigarette smoking remained the most contributable factors of NCDs in the Korean population. Moreover, other major modifiable risk factors show no improvement or even worsened. The current status and trends in major modifiable risk factors reinforce the importance of prevention, detection, and treatment of risk factors in reducing the burden of NCDs on individuals and society.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.31 no.4
• /
• pp.169-176
• /
• 2020

Exploring the risk factors of adolescent suicide is important for effective suicide prevention. This study explored the clustering of adolescent suicides based on six risk factors: mental disorder, broken family, depression, anxiety, previous suicide attempts, and deviant behaviors. Using 173 student suicide reports obtained from the Ministry of Education, we evaluated the associations between suicide and variables related to mental disorders; dysfunctional family life; depression and anxiety; previous suicide attempts; deviant behaviors such as drinking and smoking; and school life characteristics, including attendance and discipline, problems within the past year, and incidents prior to suicide. In addition, reports of warning signs just before suicide were included in the analysis. The two-stage cluster analysis classified the students into three clusters: the silent type (cluster 1; 48.55%), in which no risk factors were observed; environmental-risk type (cluster 2: 24.28%), which featured a high frequency of broken households, deviant behaviors such as smoking/drinking and running away from home; and depressive type (cluster 3: 27.17%), which featured a high frequency of mental health problems such as depression, anxiety, and suicide attempts. Identifying the sub-types of adolescent suicide may help to inform tailored suicide prevention and intervention strategies in school.

• Korean Journal of Health Education and Promotion
• /
• v.6 no.1
• /
• pp.66-74
• /
• 1989

The purpose of this study was to determine appropriate training content and methods for a health educational program for rural people by analysing data collected through a structured interview survey with the rural people of Kangwha county in June, 1987, The variables analyzed for the educational content were the diseases of greatest concern and the most urgent health problems, and for the educational methods, the health educator, place of education and types of educational media were analyzed. The results are as follows: 1. The disease of greatest concerned was gastroenteritis(22.6%), followed by diabetes(13.7%), and hepatitis (10.2%). The respondents with old age and less education were more concerned with arthritis, and those with higher education were more concerned with diabetes. 2. The most urgent health problem was agricultural chemical poisoning(46%), followed by smoking(12.8%), and the lack of balance between meals and nutrition(8.8%). The people with less education and with higher income were less concerned with agricultural chemical poisoning and smoking. 3. Of the respondents, 77.4% wanted to be educated by physicians and the village auditorium was the most preferred place of education. Education in a lecture format was desired by 36.3% of respondents. Personal counselling was more preferred by old and less educated people, and people with higher education preferred printed matters.