• 건축역사연구
• /
• 제15권5호
• /
• pp.41-56
• /
• 2006

Signal fire was a communication system which deliver urgent news by smoke and light. It informed the condition of the border to the central government and the military base rapidly. This research was to analyze the border signal-fire which is the main facility of military protective duty for safety of sea side in chosun dynasty. The results of this research were described separately as follows. 1. The border signal-fire has three types of facility layout, The majority was one-site, near two-site, separate type. The majority was near two-site type. 2. Plan configuration of signal-fire stand which is separated with circle, oval, round-rectangular and rectangular type roughly was constructed with circle type generally. Four types of signal-fire stand was observed in southern and western sea side impartially. However, in eastern side, circle type of signal-fire stand was mainly found. Therefore, regional characteristics could be considered partially. 3. The height of signal-fire stand was about 8~10m. The diameter of combustion chamber on the signal-fire stand was 2~3m in circle type, and the dimension of rectangular type was about $1.9{\times}1.9{\sim}3.2{\times}3.0m$. 4. Building base that protect ground moisture and infilteration of rainfall was found in 10 border singal-fire, the height of it was about 0.3m~2.5m.

• 한국통신학회논문지
• /
• 제12권2호
• /
• pp.139-147
• /
• 1987

본 논문에서는 디지털回路의 단일 고착형 결함(single stuck-at-type fault)에 대한 信號的 信賴度(signal reliability)를 計定하는 방법을 보였다. 디지털 회로에 있어 신호적 신뢰도라 함은 회로내부에 결함이 존재한다고 할지라도 올바른 출력을 내는 確率을 의미한다. 신호적 신뢰도를 계정함에 있어서 단일 고착형 결함에 대한 결함 모델과 알고리즘을 보이고 또한 복잡하고 규모가 큰 회로에 적용할 수 있는 컴퓨터 프로그램도 구성하였다.

• 말소리와 음성과학
• /
• 제3권3호
• /
• pp.99-108
• /
• 2011

The perturbation parameters like jitter, shimmer, and signal-to-noise ratio (SNR) are largely estimated in the particular segment from the subjective or whole portion of the given pathological voice signal although there are many possible regions to be able to analyze the voice signals. In this paper, the pathological voice signals were classified as type 1, 2, 3, or 4 according to narrow band spectrogram and the value differences of the perturbation parameters extracted in the subjective and entire portion tended to be getting bigger as from type 1 to type 4 signals. Therefore, sample selection method based on moving window to analyze type 2 and 3 signals as well as type 1 signals is proposed. Although type 3 signals cannot be analyzed using the perturbation analysis, the type 3 signals by selecting out the samples in which error count is less than 10 through moving window were analyzed. At present, there is no method to be able to analyze the type 4 signals. Future research will endeavor to determine the best way to evaluate such voices.

• Journal of Life Science
• /
• 제11권2호
• /
• pp.94-98
• /
• 2001

Type I signal peptidase cleaves the signal sequence from the amino terminus of membrane and secreted proteins afters these protein insert across the membrane. This enzyme serves as a potential target for the development of novel antibacterial agents due to its unique physiological and biochemical properties. Despite considerable research, the signal peptidase assay still remains improvement to provide further understanding of the mechanism and high-throughput inhibitor screening of this enzyme. In this paper, three known signal peptidase assays are tested with an E. coli D276A mutant signal peptidase to distinguish the sensitivity of each assays. In vitro assay using the procoat synthesized by in vitro transcription translation shows that the D276A signal peptidase I was inactive while in vivo processing of pro-OmpA expressed in the temperature-sensitive E. coli strain IT41 as well as in vitro assay using pro-OmpA nuclease A substrate show that D276A signal peptidase I has activity like wild-type signal peptidase. These results suggest that in vitro assay using the pro-OmpA nuclease A and in vivo pro-OmpA processing assay are more sensitive monitors than in vitro assay using the pro-coat. In conculsion, caution should be used when interpreting the in vitro results using the procoat.

• 말소리와 음성과학
• /
• 제6권3호
• /
• pp.63-72
• /
• 2014

The current study assessed the utility of acoustic analyses the most commonly used in routine clinical voice assessment including perturbation, nonlinear dynamic analysis, and Spectral/Cepstrum analysis based on signal typing of dysphonic voices and investigated their applicability of clinical acoustic analysis methods. A total of 70 dysphonic voice samples were classified with signal typing using narrowband spectrogram. Traditional parameters of %jitter, %shimmer, and signal-to-noise ratio were calculated for the signals using TF32 and correlation dimension(D2) of nonlinear dynamic parameter and spectral/cepstral measures including mean CPP, CPP_sd, CPPf0, CPPf0_sd, L/H ratio, and L/H ratio_sd were also calculated with ADSV(Analysis of Dysphonia in Speech and VoiceTM). Auditory perceptual analysis was performed by two blinded speech-language pathologists with GRBAS. The results showed that nearly periodic Type 1 signals were all functional dysphonia and Type 4 signals were comprised of neurogenic and organic voice disorders. Only Type 1 voice signals were reliable for perturbation analysis in this study. Significant signal typing-related differences were found in all acoustic and auditory-perceptual measures. SNR, CPP, L/H ratio values for Type 4 were significantly lower than those of other voice signals and significant higher %jitter, %shimmer were observed in Type 4 voice signals(p<.001). Additionally, with increase of signal type, D2 values significantly increased and more complex and nonlinear patterns were represented. Nevertheless, voice signals with highly noise component associated with breathiness were not able to obtain D2. In particular, CPP, was highly sensitive with voice quality 'G', 'R', 'B' than any other acoustic measures. Thus, Spectral and cepstral analyses may be applied for more severe dysphonic voices such as Type 4 signals and CPP can be more accurate and predictive acoustic marker in measuring voice quality and severity in dysphonia.

• 한국미생물·생명공학회지
• /
• 제31권2호
• /
• pp.140-144
• /
• 2003

신호펩디드 가수분해는 모든 생물에 필수적인 단백질로 N-말단에 신호서열을 가진 단백질들의 신호서열을 잘라내는 효소로 serine과 lysine을 활성부위로 하는 특이한 dyad serine 효소류로 알려져있다. 최근에 신호펩디드 가수분해효소의 특성으로 새로운 항생제 이용 가능성 때문에 그 활성 메카니즘의 연구가 중요시되고 있다. 본 연구는 E. coli 신호펩디드 효소가 serine/lysine/aspartic acid로 하는 전형적인 triad serine 효소류의 메카니즘을 갖는다는 가정하에 Type Ⅰ 신호펩디드류의 하나인 E. coli에서 aspartic acid 99을 alanine으로 치환하여 효소의 enzymatic activity를 조사하였다. 그 결과 D99잔기는 E. coli Type Ⅰ 신호펩디드 효소의 활성메카니즘에 직접적으로 관여한다기보다는 그 효소를 구조적으로 안정화하는데 중요한 역할을 할 가능성이 있는 것으로 암시되어진다.

• Imaging Science in Dentistry
• /
• 제31권2호
• /
• pp.93-99
• /
• 2001

Purpose: To analyze the possible association between magnetic resonance imaging signal intensity of temporomandibular joint disk and posterior attachment, and the type and extent of disk displacement, disk configuration, effusion and clinical signs in patients with internal derangement. Materials and Methods: Magnetic resonance images of the 132 temporomandibular joints of 66 patients with temporomandibular joint displacement were analyzed. The clinical findings were obtained by retrospective review of the patients' records. The type and extent of disk displacement, disk configuration and effusion were evaluated on the proton density MR images. The signal intensity from the anterior band, posterior band and posterior attachment were measured on MR images. The associations between the type and extent of disk displacement, disk configuration, effusion and clinical signs and the MR signal intensity of disk and posterior attachment were statistically analyzed by student's t-test. Results: Of 132 joints, 87 (65.9%) showed anterior disk displacement with reduction (ADR) and 45 (34.1%) showed anterior disk displacement without reduction (ADnR). The signals from posterior attachments were lower in joints with ADnR than those of ADR (p<0.05). The results showed statistically significant (p<0.05) association between the type and extent of disk displacement and disk configuration, and decreased signal intensity of posterior attachment. There were no statistical associations between pain, noise and limited mouth opening, and signal intensity of disk and posterior attachment. Conclusions: The average signal from posterior attachment was lower in joints with ADnR than that of ADR. The type and extent of disk displacement and disk configuration appeared to be correlated with the signal intensity from posterior attachment.

• 미생물학회지
• /
• 제36권4호
• /
• pp.254-258
• /
• 2000

소장의 상피세포내로 세균 세포가 들어가는 과정(invasion)은 Salmonella의 감염에서 중요한 단계이다. invasion은 Salmonella type III 분비장치에 의해 분비되는 단백질들에 의해 유도된다. type III 분비단백질들은 특이하게, 일반적인 분비단백질들이 가지는 N-말단 분비 신호 펩타이드를 가지고 있지 않는 것을 알려져 있다. Yersinia에서의 최근 연구에서 type III 분비장치에 의해 인지되는 분비신호는 분비 단백질을 암호화하는 mRNA의 5'말단부의가 형성하는 2차 구조에 있을 것이라는 보고가 있다. 본 연구에서는 Salmonella type III 분비장치의 분비신호를 조사하기 위해 type III 분비단백질중 하나인 sopE를 택하여 ompR과의 translational fusion을 만들었다. translational fusion을 위해 사용된 sopE DNA절편은 프로모터와 시작 콘돈으로부터 10, 15 코돈을 포함하는 절편이다. Immunoblot으로 확인한 결과, OmpR을 포함하는 fusion 단백질이 형질전환 Salmonella 세포로부터 분비되었다. 이러한 결과는 Salmonella의 type III 분비신호가 분비단백질을 암호화하는 mRNA의 5'말단에 위치할 가능성을 제시하고 있다. 또한, 이러한 분비신호를 활용하여 유용한 외래 단백질을 세균 세포 내에서 효과적으로 생산, 분비할 수 있는 secretion vector의 원형을 개발하였다.

• 건축역사연구
• /
• 제17권2호
• /
• pp.47-66
• /
• 2008

This research was to analyze the border signal-fire which is the main facility of military protective duty for safety of sea side in chosun dynasty. The results of this research were described separately as follows. 1. Five types of site plan of signal-fire were observed, which is circle, half-circle, oval, round-rectangular. The majorities were circle type in eastern area. 2. Plan configuration of signal-fire stand which is separated with circle, rectangular type roughly was constructed with circle type generally. The height of signal-fire stand was about $2{\sim}3m$. The diameter of signal-fire stand was $8{\sim}10m$. Building base that protect ground moisture and infilteration of rainfall was found in 9 border singal-fire, the height of it was about $0.3m{\sim}2.5m$. 3. Trench was mainly circle type and average width was $3{\sim}4m$. However the depth was almost observed as 1m, originally, it was estimated it has more depth. 4. The height of protective wall remained until present was about 1m, the depth was about average 2.5m. 5. The storage of border signal-fire has rectangular dimension, several types of $1.8{\times}1.2m{\sim}5.7{\times}4.4m$, square(間) of $1{\times}1{\sim}2{\times}1$. The building material was stone and located below or near the signal-fire stand.

• 한국통신학회논문지
• /
• 제32권1C호
• /
• pp.59-66
• /
• 2007

본 논문에서는 ISO/IEC 18000-6 Type-B RFID 시스템에서 태그 응답신호, 즉 리더 수신신호에서 허용오차 (Tolerance)와 잡음이 미치는 영향에 대해서 알아보고, 이에 대한 영향을 최소화하는 방법을 제안한다. 제안된 방법은 오버 샘플링된 수신 신호를 가지고 가변천이검출윈도우를 이용하여 허용오차에 의한 영향을 제거하고 비트가 천이되는 위치를 검출하며, 이전의 비트 천이에서 현재 비트 천이까지의 윈도우 내 수신 신호를 평균하여 잡음의 효과를 줄인다. 제안된 방법을 적용하여 자체 제작한 리더에서 성능 테스트한 결과를 상용리더와의 비교 실험결과로 제시한다.