• Communications for Statistical Applications and Methods
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• v.31 no.5
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• pp.571-584
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• 2024

To identify differentially expressed genes (DEGs), researchers use a testing method for each gene. However, microarray data are often characterized by large dimensionality and a small sample size, which lead to problems such as reduced analytical power and increased number of tests. Therefore, we propose a clustering method. In this method, genes with similar expression patterns are clustered, and tests are conducted for each cluster. This method increased the sample size for each test and reduced the number of tests. In this case, we used a nonparametric permutation test in the proposed method because independence between samples cannot be assumed if there is a relationship between genes. We compared the accuracy of the proposed method with that of conventional methods. In the simulations, each method was applied to the data generated under a positive correlation between genes, and the area under the curve, power, and type-one error were calculated. The results show that the proposed method outperforms the conventional method in all cases under the simulated conditions. We also found that when independence between samples cannot be assumed, the non-parametric permutation test controls the type-one error better than the t-test.

• The Journal of Korean Physical Therapy
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• v.14 no.1
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• pp.75-88
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• 2002

The purpose of this study was to investigate the influence of anterior, posterior, and lateral pelvic tilt exercise upon the gait characteristics of patients with hemiplegia including their gait velocity, cadence, stride length, step length of the non affected side, step length of the affected side, foot angle of the non affected side, foot angle of the affected side, base of support, and so on. The subject of this study was 24 men and women patients with hemiplegia. The patients, the subject of this study, were classified into 12 patients of treatment group applying pelvic tilt exercise using visual feedback and 12 patients of control group applying general pelvic tilt exercise, and then analyzed their gait before and after exercise. Temporal distance gait analysis (Boening, 1977) was used to analyze their gait, and ink foot-print was applied as on of measurement methods. To find out meaningful difference between control group and treatment group, this study carried out independent sample t-test for each item by utilizing SPSS/Win 10.0, compared changes in control group's and treatment group's gait characteristics before and after exercise as percentage, and applied paired t-test to conduct before-after test in same group. Statistical significance level was ${\alpha}$ < 0.05. The results of this study were as follows. As a result of independent sample t-test for control group's and treatment group's gait characteristics after exercise, it was not statistically significant so there was no meaningful difference between two groups. However, it was statistically significant in the change rate(%) of gait characteristics, and treatment group's patients with hemiplegia had been highly changed in gait characteristics in comparison with control group. From the above-mentioned results, could find that pelvic tilt exercise using visual feedback for patients with hemiplegia was effective to improve their gait ability and it could increase the ability in comparison with general pelvic tilt exercise. In the future, studies on the effect of pelvic tilt exercise using visual feedback shall be continued based on more quantitative methods.

• Journal of East-West Nursing Research
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• v.19 no.2
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• pp.104-113
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• 2013

Purpose: Due to the academic demands from a theory and practice-based educational program, nursing students often experience psychological burdens. The purpose of this study was to investigate the effect of mindfulness meditation programs on nursing students' perceived stress, depression, and self-efficacy. Methods: A quasi-experimental study with a non-equivalent control group pretest-posttest design was used. Participants were recruited from two nursing colleges. The sample consisted of an intervention group (n=29) that participated in a mindfulness meditation program and a control group (n=30). The experimental group participated in the program for 120 minutes a week for a total of 8 sessions. The data were collected prior and after the intervention using self-administered questionnaires. Data were analyzed using descriptive statistics, $X^2$-test, Fisher's exact probability test, and the t-test. Results: After the application of the mindfulness meditation program, the experimental group showed a significant difference in perceived stress(t=-10.33, p<.001), depression (t=-2.17, p=.035), and self-efficacy (t=2.57, p=.013) scores. However, there was no significant differrence in the control group. Conclusion: These findings provide a supportive evidence of mindfulness meditation program as a behavioral intervention to reduce stress, depression and increase self-efficacy among nursing students.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.4
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• pp.205-217
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• 2011

Objectives: This study was conducted to identify the effects of the Daoyin and corrective exercise program on musculoskeletal pain among acute sprain patients due to traffic accidents. Methods: This study was carried out on the 35 patients who had been treated on musculoskeletal pain due to traffic accidents and was performed from March 1 to June 31, 2011 in the department of oriental rehabilitation medicine, Dun-San oriental hospital attached Dae-Jeon university. And we divided those 35 patients into 2 groups; sample group took treated with the Daoyin and corrective exercise program control group took common treatment only. All of the subjects were examined en visual analogue scale(VAS), state-trait anxiety inventory(STAI) score and presence of treatment after hospital discharge. The data was collected before and after the treatment, after hospital discharge. SPSS ver. 12.0 for Windows was used fer data analysis, and the analysis, and the general characteristics were demonstrated by frequency number and two-independent sample t-test. The effects of the Daoyin and corrective exercise program were analyzed by matched pair t-test and analysis of covariance. Results: On the VAS score, there was significant difference between before and after treatment, and before and after hospital discharge. And on the VAS scores, sample group mowed higher significant change of VAS than control group. And on the STAI score, there was significant difference between before and after treatment. But it did not show statistical significance between sample and control group. Conclusions: The Daoyin and corrective exercise program is an effective treatment fer musculoskeletal pain among acute sprain patients due to traffic accidents.

• Phonetics and Speech Sciences
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• v.3 no.3
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• pp.149-155
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• 2011

The purpose of the present study was to identify the differences in GRBAS scales between vocal sample types (sustained vowels and connected speech) for specific laryngeal conditions (vocal nodules, vocal polyps and vocal paralysis) and the relations between GRBAS scale and Shimmer value in each vocal sample type. In this study, the total of 60 voice samples of 30 patients (10 vocal nodules, 10 vocal polyps, 10 vocal paralysis) were examined and MDVP (Multi-dimensional Voice Program) was used to analyze Shimmer value. Three listeners rated two types of samples which were sorted randomly based on GRBAS scale. Three-way ANOVA, one-way ANOVA and paired t-test were used. The outcome of this study was as follow. 1) GRBAS scales varied in vocal sample types. Listeners tended to assess voices as better quality when they listened connected speech rather than sustained vowels. 2) G score of GRBAS and Shimmer were positively correlated with statistical significance. This results show that 1) vocal specialists should consider the sample types in evaluating the severity of voice problem and 2) G score could be a simple and clear method.

• Journal of Convergence for Information Technology
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• v.11 no.10
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• pp.68-73
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• 2021

This study was to identify the effects of using Gratitude Diary Writing on self-esteem and internal-external locus of control to adolescent. A randomized controlled experimental design was used. There were 20 participants in the experimental group, and 19 in the control group. Data were analyzed using Chi-square test, Fisher's exact test, t-test. The results of self-esteem(t=5.142, p=<.001) and internal-external locus of control(t=5.821 p=<.001)l showed statistically significant differences between the two groups. Using thank journal writing is effective in improving adolescents self-esteem and internal-external locus of control. If the gratitude diary writing effect of gratitude is verified by selecting a wide sample, it is expected that it will be helpful for generalize activities.

• The Korean Journal of Rehabilitation Nursing
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• v.15 no.1
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• pp.63-71
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• 2012

Purpose: The purpose of this study was to determine the effects of a fall prevention program on gait ability, one leg standing-right, one leg standing-left, fear of falling, fall efficacy, and depression in the elderly. Methods: A fall prevention program was consisted of fall preventing exercise with laughter therapy. Quasi-experimental design with one group pre- and post-test was used. Twenty-two elderly were participated in this study from a community health center located in a rural area, South Korea. SPSS/WIN 18.0 was used for descriptive analysis and paired t-test. Results: After 12 weeks with a fall prevention program, gait ability (t=3.44, p=.002), one leg standing-right (t=-3.73, p=.001), one leg standing-left (t=-4.17, p<.001) and fear of falling (t=2.12, p=.046) in the elderly were significantly improved. Conclusion: A fall prevention program was effective on physical and psychological functions. This study suggested that control groups and a larger sample should be included in order to validate the effects of a fall prevention program for the elderly. Key Words: Elderly, Fall prevention program, Physical functions, Psychological

• Journal of Korean Academy of Nursing
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• v.34 no.3
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• pp.525-533
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• 2004

Purpose: The purpose of this study was to develop a program promoting adjustment to hospital life and determining its effectiveness for school aged children. Method: The sample group consisted of 76 hospitalized children in 2 University Hospitals located in Busan. The experimental group was given the program on admission and feedback was obtained on the 3rd day and again 24 hours later. Data was analyzed using t-test and ANOVA in the SPSS program package. Result: There were significant differences, in information(t=4.235, p=0.000) and coping effort criteria (t=2.922, p=0.005) between the experimental and control groups. There was a non-significant difference in attitude criteria between the two groups(t=1.009, p=0.316). Conclusion: It was found that the adjustment promoting program for hospital life for school aged children was effective, but not enough to promote self-esteem. The program, based on a learning theory, was improved and shown to be an effective and strong method to promote adjustment of school-aged children.

• Genomics & Informatics
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• v.2 no.4
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• pp.180-183
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• 2004

Comparative Statistic Module(CSM) provides more reliable list of significant genes to genomics researchers by offering the commonly selected genes and a method of choice by calculating the rank of each statistical test based on the average ranking of common genes across the five statistical methods, i.e. t-test, Kruskal-Wallis (Wilcoxon signed rank) test, SAM, two sample multiple test, and Empirical Bayesian test. This statistical analysis module is implemented in Perl, and R languages.

• Journal of Convergence for Information Technology
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• v.10 no.11
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• pp.224-231
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• 2020

This study was conducted to develop a group counseling program to solve the problem of maladjustment of military personnel and to verify the effectiveness of the program. The 12 session CBT and ACT program for military soldiers experiencing emotional and behavioral problems was developed and the effectiveness was verified by conducting a program once a week for soldiers in the army units based in South Chungcheong Province. Adult Self Report scale(ASR) was implemented for pre-post test and analysis, and descriptive statistical analysis, cross-analysis, paired sample t-test, and independent sample t-test were performed to analyze the results. The results indicated are as follows: First, the preliminary homogeneity test between groups showed that the two groups had homogeneous demographic characteristics and the characteristics of the variables. Second, as a result of the pre-post test verification, both CBT and ACT groups showed significant changes in problem behavior totals, internalizations, and externalizations. Third, there was no difference between the pre-post-examination of the CBT group and the ACT group. This study is meaningful in that it was involved in the maladjustment problem within the military unit, and compared the effectiveness between the two theories, and proposed the study of control groups and further studies on more diverse and diverse subjects that were not implemented under the circumstances of the unit.