• Title/Summary/Keyword: Triple-helix

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Multidisciplinary Team Research as an Innovation Engine in Knowledge-Based Transition Economies and Implication for Asian Countries -From the Perspective of the Science of Team Science

  • Lee, Yong-Gil
    • Journal of Contemporary Eastern Asia
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    • v.12 no.1
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    • pp.49-63
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    • 2013
  • This work identifies the key factors influencing the success of multidisciplinary, interdisciplinary, and trans-disciplinary R&D projects in transition economies by integrating knowledge management, organizational, inter/intra-collaboration (open-innovation), and leadership perspectives, while also addressing the perspective of the science of team science, which is an integrative approach to R&D. This is followed by providing the major sub-constructs of team science and policy implications to better facilitate multidisciplinary, interdisciplinary, and transdisciplinary R&D projects in knowledge-based transition economies.

Assessing Losers Consent in Mixed Systems: Public Perceptions of Taiwan’s 2008 Legislative Yuan Election

  • Rich, Timothy S.
    • Journal of Contemporary Eastern Asia
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    • v.15 no.1
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    • pp.4-16
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    • 2016
  • A large literature identifies perceptual differences between citizens that support winning parties versus losing parties. These analyses fail to capture the complexity of mixed member legislative systems where one can be a winner or loser at both the national and district level. This paper proposes a two-level framework for the analysis of mixed system. An analysis of Taiwan’s first election under a mixed system provides evidence that both support for a national winner and district level winner produce boosts in positive perceptions of the electoral system. National success appears to be a larger motivator of perceptions.

The Korean State and Candlelight Democracy: Paradigms and Evolution

  • Bedeski, Robert
    • Journal of Contemporary Eastern Asia
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    • v.16 no.2
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    • pp.82-92
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    • 2017
  • The Korean state evolved as a distinct entity in a region of major power convergence and conflict. All states, as human constructions, seek sovereignty and life security of their subjects/citizens, and are rotted in organic society. In the Republic of Korea, constitutional order has provided a framework for political action and a succession of regimes - authoritarianism, military dictatorship, and constitutional democracy. Since 1960 two paradigms have undergone a cycle of growth and decline, and a third, since the 2016 candlelight demonstrations in Gwanghwamun, may be the beginnning of a third generation paradigm - populist constitutionalism.

Segmenting Chinese Texts into Words for Semantic Network Analysis

  • Danowski, James A.
    • Journal of Contemporary Eastern Asia
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    • v.16 no.2
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    • pp.110-144
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    • 2017
  • Unlike most languages, written Chinese has no spaces between words. Word segmentation must be performed before semantic network analysis can be conducted. This paper describes how to perform Chinese word segmentation using the Stanford Natural Language Processing group's Stanford Word Segmenter v. 3.8.0, released in June 2017.

Japan's "Last Hope": Myanmar as an arena for Sino-Japanese competition, coordination and global standardization

  • Zappa, Marco
    • Journal of Contemporary Eastern Asia
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    • v.20 no.2
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    • pp.278-297
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    • 2021
  • Despite competing strategical interests over Southeast Asia that have emerged in the last decade, with the launch of wide scope geopolitical strategies Chinese and Japanese initiatives have been characterized by a certain degree of implicit coordination, particularly in offering support to the Myanmar state's territorializing strategies for economic development. The case of the Thilawa Special Economic Zones (SEZ) is exemplary, as it was a Japan-led project which became a model and benchmark example for similar development initiatives supported by the People's Republic of China.

Online Information Sources of Coronavirus Using Webometric Big Data (코로나19 사태와 온라인 정보의 다양성 연구 - 빅데이터를 활용한 글로벌 접근법)

  • Park, Han Woo;Kim, Ji-Eun;Zhu, Yu-Peng
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.21 no.11
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    • pp.728-739
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    • 2020
  • Using webometric big data, this study examines the diversity of online information sources about the novel coronavirus causing the COVID-19 pandemic. Specifically, it focuses on some 28 countries where confirmed coronavirus cases occurred in February 2020. In the results, the online visibility of Australia, Canada, and Italy was the highest, based on their producing the most relevant information. There was a statistically significant correlation between the hit counts per country and the frequency of visiting the domains that act as information channels. Interestingly, Japan, China, and Singapore, which had a large number of confirmed cases at that time, were providing web data related to the novel coronavirus. Online sources were classified using an N-tuple helix model. The results showed that government agencies were the largest supplier of coronavirus information in cyberspace. Furthermore, the two-mode network technique revealed that media companies, university hospitals, and public healthcare centers had taken a positive attitude towards online circulation of coronavirus research and epidemic prevention information. However, semantic network analysis showed that health, school, home, and public had high centrality values. This means that people were concerned not only about personal prevention rules caused by the coronavirus outbreak, but also about response plans caused by life inconveniences and operational obstacles.

Effect of Substituted Residue 139 and 258 on Structural Changes of Mutant Tryptophan Synthase Pro96→Leu α-Subunit (트립토판 중합효소 α 소단위 잔기 치환체 Pro96→Leu의 구조 변화에 영향을 미치는 139 및 258 잔기의 치환 효과)

  • Lee, Joo-Youn;Jeong, Jae-Kap;Shin, Hae-Ja;Lim, Woon-Ki
    • Journal of Life Science
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    • v.12 no.4
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    • pp.464-468
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    • 2002
  • Enzymatic activities and fluorescence spectroscopic properties of the double mutant proteins P96L/F139W, P96L/F258W and a triple mutant protein P96L/F139W/F258W of tryptophan synthase $\alpha$ subunit from Escherichia coli was examined to study tertiary and local structure changes around the tryptophan residues. The enzymatic activities of P96l./F139W and P96L/F258W were similar, but P96L/F139W/F258W had lower activity, as compared to wild type. The fluorescence intensities of double mutant, P96L/F139W and P96L/F258W, were decreased but that of a triple mutant, P96L/F139W/F258W, was increased when compared to wild type. The sum of the maximum fluorescence intensity (fluorescence intensity at the λ$_{max}$) for the double mutant proteins was not equal to the intensity seen in the triple mutant protein. The enzymatic activity and fluorescence data indicate that the replacement of Pro$^{96}$ longrightarrowLeu might affect on the stability of helix 8 and the loop located between strand 4 and helix4. The result suggests that the tertiary structure of triple mutant (P96L/F139W/F258W), being different from wild type, might have more compact residual structure at the vicinity of 139 and 258.8.

Study of Macrophage Activation and Structural Characteristics of Purified Polysaccharides from the Fruiting Body of Hericium erinaceus

  • Lee, Jong-Seok;Min, Kyoung-Min;Cho, Jae-Youl;Hong, Eock-Kee
    • Journal of Microbiology and Biotechnology
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    • v.19 no.9
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    • pp.951-959
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    • 2009
  • Most, if not all, Basidiomycetes mushrooms have biologically active polysaccharides showing potent antitumor activity with immunomodulating properties. These polysaccharides have various chemical compositions and belong primarily to the $\beta$-glucan group. In this study, the crude water-soluble polysaccharide HEF-P, which was obtained from the fruiting body of Hericium erinaceus by hot water extraction and ethanol precipitation, was fractionated by DEAE-cellulose and Sepharose CL-6B column chromatographies. This process resulted in four polysaccharide fractions, named HEF-NP Fr I, HEF-NP Fr II, HEF-AP Fr I, and HEF-AP Fr II. Of these fractions, HEF-AP Fr II was able to upregulate the functional events mediated by activated macrophages, such as production of nitric oxide and expression ofcytokines (IL-1${\beta}$ and TNF-${\alpha}$). The molecular mass of HEF-AP Fr II was estimated by gel filtration to be 13 kDa. Its structural characteristics were investigated by a combination of chemical and instrumental analyses, including methylation, reductive cleavage, acetylation, Fourier transform infrared spectroscopy (FT-IR), and gas chromatography-mass spectrometry (GC-MS). Results indicate that HEF-AP Fr II is a low-molecular-mass polysaccharide with a laminarin-like triple helix conformation of a ${\beta}$-1,3-branched-${\beta}$-1,6-glucan.