• Asian-Australasian Journal of Animal Sciences
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• 제20권9호
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• pp.1402-1406
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• 2007

Thirty pregnant heifers (Jersey, Holstein Friesian and Hariana) were divided into three groups (10 animals/group) according to their stage of pregnancy viz. seven-month (181-210 days) pregnancy (SMP), eight-month (211-240 days) pregnancy (EMP) and nine-month (241-280 days) pregnancy (NMP) group. Time spent in various feeding activities (eating fodder, eating concentrate, standing rumination, sitting rumination and drinking) by each animal in the three pregnant groups was recorded in four different sessions (each session of 24 h per week). The time spent eating concentrate, eating fodder, standing rumination, sitting rumination and drinking was 61.4, 271.3, 84.6, 367.6 and 10.6 min/day, respectively in the SMP group; 52.7, 289.5, 103.3, 345.8 and 9.2 min/day, respectively in the EMP group and 65.0, 277.7, 138.1, 291.0 and 9.8 min/day, respectively in the NMP group. The animals in the EMP group spent significantly (p<0.01) more time on eating fodder and concentrate compared to the animals in SMP and NMP groups. The pregnant heifers preferred rumination in standing posture in comparison to sitting posture. The time spent on standing rumination was significantly higher in the NMP group whereas the time spent on sitting rumination was significantly lower in this group. Except for the sitting rumination activity, all the other activities were predominant in daytime compared to night time; the diurnal variation was significant (p<0.01) for all the activities.

• Journal of Genetic Medicine
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• 제2권1호
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• pp.7-10
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• 1998

The present report describes a case that showed a normal fetal karyotype in an antenatal genetic study but an abnormal placental karyotype of 46,XX,r (15) on postnatal examination. The pregnancy was complicated by fetal nuchal translucency in the first trimester and intrauterine growth restriction in the second and third trimesters. A 1780 gm female baby was born after 40 weeks of gestation, but died of respiratory distress and sepsis on the 10th day of life. Our case was unique in that the placental chromosomal aberration was a structural abnormality instead of a numerical aberration that is seen in most reported cases of confined placental mosaicism.

• 대한의생명과학회지
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• 제14권4호
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• pp.233-238
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• 2008

Gestational diabetes mellitus (GDM) is a common complication during pregnancy and one of the main causes of adverse fetal-maternal outcomes. However, the pathogenesis of GDM has not been clearly stated. Adiponectin, an adipose tissue-derived plasma protein, is involved in regulation of insulin resistance and glucose hemostasis, and thus is a key modulator of insulin action and glucose metabolism. In this study, we investigated to compare serum adiponectin levels in pregnant women with diabetes, pregnant women who are without diabetes, and non-pregnant women, and to evaluate relationship between serum adiponectin. levels and metabolic parameters. Forty-one pregnant women with diabetes, fifty-nine pregnant women without diabetes and forty non-pregnancy women were recruited. Adiponectin levels were significantly lower in pregnant women with diabetes when compared to non-pregnant women and pregnant women without diabetes. Pregnant women without diabetes at second trimester had lower adiponectin levels compared to non-pregnant women. Adiponectin was negatively correlated with BMI, fasting insulin, HOMA-IR, total cholesterol, and triglyceride. In conclusion, this study confirmed that the decreased level of adiponectin precedes the onset of abnormal glucose level during pregnancy and also normal pregnant women had lower adiponectin levels compared to non-pregnant women. This knowledge may help to identify strategies for lowering the occurrence of GDM in women who are at high risk of developing the disorder.

• Journal of Nutrition and Health
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• 제34권8호
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• pp.929-935
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• 2001

The purpose of this study was to investigate the effects of regular maternal exercise on maternal nutrients intake and pregnancy outcome. The number of subjects were 567 pregnant women at local general hospital in Daegu. General characteristics data and 24- hour food recalls were collected by trained interviewer. Structured interview and medical record review were carried out at first prenatal and delivery visit(included age, delivery history, height, pre-pregnancy weight, and pregnancy outcome etc). Regular exercise performance was surveyed at third trimester and 31.4% of subjects exercised regularly Overall weight gains during pregnancy were 13.9 $\pm$ 3.8kg and 14.7 $\pm$ 4.7kg in the exercise and sedentary group, respectively. The type of exercise was mainly strolling and light aerobic exercise. Usually firstpara subjects exercised more regularly than multipara subjects. There is no significant difference between regular exercise and severity of morning sickness. Weight gain during pregnancy was not relate to regular exercise. Though there is not statistically significant, the nutrients intakes were higher in regular exercise group than in sedentary group. We concluded regular exercise during pregnancy neither influenced pregnancy weight gain, severity of morning sickness nor baby birth weight but it could affect the nutritional and health statues of mother.

• Journal of Korean Neurosurgical Society
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• 제45권1호
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• pp.39-42
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• 2009

We report a supratentorial primitive neuroectodermal tumor (sPNET) in 17-year-old primipara in the second trimester her pregnancy. Magnetic resonance imaging revealed a left frontoparietal mass with solid and cystic component. Gross-total resection was achieved via a left frontoparietal craniotomy. It was decided to suspend the radiotherapy and chemotherapy until the 30 weeks of gestation. But, a sudden uncal herniation was developed due to the reccurrence of the tumor and bleeding into the tumor at the 25 weeks of gestation and the patient died after urgent decompressive surgery. sPNETs is an extremely rare brain tumor in pregnancy and only two cases were reported in the literature to date. There is no universally agreed treatment protocol for sPNETs during pregnancy and a multidisciplinary approach is required in treatment. In the present study, the clinical, histopathological features and therapeutical difficulties of sPNETs diagnosed during pregnancy was discussed with the literature review.

• Toxicological Research
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• 제20권3호
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• pp.187-193
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• 2004

This study aimed to determine the association of maternal oxidative stress and adverse pregnancy outcome with serum vitamin C concentration and a myeloperoxidase (MPO) genetic polymorphism during pregnancy. We investigated 450 pregnant women who visited Ewha Womans University Hospital for prenatal care during gestational weeks 24～28. During the second trimester, we measured serum vitamin C levels and urinary 8-hydroxyde-2'-deoxyguanosine (8-OHdG) and malondialdehyde (MDA) as an oxidative stress biomarker. We determined the presence of a maternal MPO polymorphism (G-to-A substitution at nucleotide 463) using a PCR-RFLP assay. We compared the level of oxidative stress and birth weight with the vitamin C concentration and the presence of the MPO polymorphism. The mean level of maternal oxidative stress tended to be higher and the birth weight lower for MPO type A/A than for types A/G and G/G. Vitamin C levels above the 75 percentiles were associated with reduced concentrations of urinary MDA and 8-OHdG but increased birth weight. Our data demonstrate that oxidative stress and neonatal birth weight are associated with the MPO genetic polymorphism, with the association modified by the maternal vita-min C levels.

• 대한지역사회영양학회지
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• 제3권1호
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• pp.53-61
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• 1998

This study was designed to estimate mean daily iron intake and its bioavailabi- lity and to assess nutrition knowledge for 144 pregnant women in the last trimester. Serum ferritin concentration was analyzed to estimate their iron stores. Dietary intakes of iron(heme iron and nonheme iron), the amounts of MPF(meat, poultry and fish) and ascorbic acid were assessed by modified 24-hr recall method. The food frequency questionnaire was used to assess subjects usual food consumption patterns. The mean value of serum ferritin was $21.3\pm{15.2ng/ml}$ and 26.4% of the pregnant women had a serum ferritin level <12ng/ml(i.e. depleted iron stores). The mean daily intake of total orin in the pregnant women was 56.5%(17.0mg) of RDA and heme iron intake was 0.94mg which was 5.5% of total iron intake. Total absorbable iron calculated by the method of Monsen was 2.41mg and bioavailability of dietary iron was 2.41%. Food frequency test score of meats group was positively correlated(r=0.443) with the bioaavailability of dietary iron. The mean score on the nutrition knowledge test of subjects was 12.76(out of a possible 20 points). These results indicate that the nutritional iron status may be improved by increasing either the amount of iron in the diet or its availability.

• 한국동물생명공학회지
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• 제34권4호
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• pp.318-321
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• 2019

Recent studies showed that tight junctions (TJs) integrity and assembly are required for blastocyst development in mouse and pig models. However, the biological functions of TJs associated with embryo implantation and maintenance of pregnancy were not investigated yet. To examine whether disrupted TJs affect further embryo development, we employed RNAi approach and inhibitor treatment. The embryos were injected with Cxadr (Coxsackievirus and adenovirus receptor) siRNA for knock down (KD) and treated with Adam10 (A Disintegrin and Metalloproteinase specific inhibitor 10; GI254023X; SI). We compared blastocyst development and paracellular sealing assay using FITC dextran uptake between control and KD or SI embryos. Finally, we transferred control and Cxadr KD or Adam 10 SI treated blastocyst to uteri of recipients. Cxadr KD and Adam 10 SI showed lower blastocyst development and more permeable to FITC-dextran. Moreover, we observed that half of KD and inhibited embryos failed to maintain pregnancies after the second trimester. Our findings suggested that TJs integrity is required for the maintenance of pregnancy and can be used as a selective marker for the successful application of assisted reproduction technologies.

• 여성건강간호학회지
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• 제11권3호
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• pp.225-231
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• 2005

Purpose: This study was done to compare prenatal education programs for anxiety and labor efficacy in third trimester women. Method: The subjects were 95 primigravida who attended a prenatal education program at H and B hospital in Kyounggi province and a health center in Chungbuk province and in the Incheon metropolitan area. Data was collected using a structured questionnaire, and trait and state anxiety, and labor efficacy were measured. The data was analyzed by frequency, mean, and paired t-test. Result: In this study, there was a high level of anxiety in the primigravida. After the program, only state anxiety was decreased significantly at the attendants of the health center. Labor efficacy was a little increased, but this was not significant. Anxiety was increased and labor efficacy was decreased in the attendant of a private hospital. Conclusion: These education programs were not so effective to decrease anxiety and to increase labor efficacy. For on effective program to increase labor efficacy, it is necessary to standardize prenatal education program content and to revise it to decrease state anxiety closer to delivery. It is necessary to discover why these programs were not effective.

• 여성건강간호학회지
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• 제10권1호
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• pp.8-14
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• 2004

Purpose: The purpose of this study was to look into back pain, pain disability, labour pain, and related areas of pain experienced by postpartum women. Method: A survey about pain including a Visual Analogue Scale (VAS), Oswestry pain disability, and pain drawing was used in a descriptive research method on 98 women 2-3 days after delivery. Result: 57.1% of those surveyed reported experiencing back pain before pregnancy. 75.5% reported experiencing back pain during pregnancy. The average starting time of back pain for pregnant women was 2.9 months into pregnancy. 48.8% reported the most severe back pain in the last trimester of pregnancy, while most women complained of left and right pubic pain and lumbar area pain during pregnancy. Statistical relations were calculated and menstrual symptoms (F=5.938, p=0.004), back pain prior to pregnancy (F=4.714, p=0.000), back pain during pregnancy (F=-3.429, p=0.001), and back pain disability prior to pregnancy (F=-1.994). Conclusion: There is a relation in postpartum women's back pain between back pain prior to pregnancy and back pain during pregnancy. Pelvic examinations early in pregnancy can determine if back pain will change for the worse or relapse. Therefore, the application of a pain relieving nursing intervention is needed.