• Korean Journal of Veterinary Research
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• v.51 no.4
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• pp.253-257
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• 2011

Amikacin is a semisynthetic derivative of kanamycin and primarily active against aerobic Gram-negative-pathogens with limited activity against Gram-positive bacteria. Meager study was reported on pharmacokinetic data on multi-days administration of amikacin. Hence, pharmacokinetics study was done in five clinically healthy goats (n = 5), after intravenous bolus injection of amikacin sulfate at the dose rate of 10 mg/kg body weight daily for three consecutive days. The amikacin concentrations in plasma and pharmacokinetics-parameters were analyzed by using microbiological assay technique and noncompartmental open-model, respectively. The mean peak plasma concentrations (Mean ${\pm}$ SD) of amikacin at time zero ($Cp^{0}$) was $114.19{\pm}20.78$ and $128.67{\pm}14.37{\mu}g/mL$, on day 1st and 3rd, respectively. The mean elimination half-life ($t_{1/2}ke$) was $1.00{\pm}0.28h$ on day 1st and $1.22{\pm}0.29h$ on day 3rd. Mean of area under concentration-time curve ($AUC_{0{\rightarrow}{\infty}}$) was $158.26{\pm}60.10$ and $159.70{\pm}22.74{\mu}g.h/mL$, on day 1st and 3rd respectively. The total body clearance ($Cl_{B}$) and volume of distribution at steady state (Vdss) on day 1st and 3rd were $Cl_{B}=0.07{\pm}0.02$ and $0.06{\pm}0.01L/h.kg$ and $Vdss=0.10{\pm}0.03$ and $0.11{\pm}0.05L/kg$, respectively. No-significant difference was noted in both drug-plasma concentration and pharmacokinetics-parameters, respectively. Amikacin concentration in plasma was found higher up-to 4 h and 6 h onward on down-ward trends favour to reduce toxicity. Which also support the pharmacokinetic-pharmacodynamic way of dosing of aminoglycosides and hence, amikacin may be administered 10 mg/kg intravenously daily to treat principally Gram-negative pathogens and limitedly Gram-positive-pathogens.

• Journal of Wetlands Research
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• v.17 no.3
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• pp.251-263
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• 2015

This study suggested a novel approach of estimating the optimal probability density function (OPDF) of the annual maximum rainfall time series (AMRT) combining the L-moment ratio diagram and the geographical information system. This study also reported several interesting geographical characteristics of the AMRT in Korea. To achieve this purpose, this study determined the OPDF of the AMRT with the duration of 1-, 3-, 6-, 12-, and 24-hours using the method of L-moment ratio diagram for each of the 67 rain gages in Korea. Then, a map with the Thiessen polygons of the 67 rain gages colored differently according the different type of the OPDF, was produced to analyze the spatial trend of the OPDF. In addition, this study produced the color maps which show the fitness of a given probability density function to represent the AMRT. The study found that (1) both L-skewness and L-kurtosis of the AMRT have clear geographical trends, which means that the extreme rainfall events are highly influenced by geography; (2) the impact of the altitude on these two rainfall statistics is greater for the mountaneous region than for the non-mountaneous region. In the mountaneous region, the areas with higher altitude are more likely to experience the less-frequent and strong rainfall events than the areas with lower altitude; (3) The most representative OPDFs of Korea except for the Southern edge are Generalized Extreme Value distribution and the Generalized Logistic distribution. The AMRT of southern edge of Korea was best represented by the Generalized Pareto distribution.

• Clean Technology
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• v.21 no.3
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• pp.141-152
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• 2015

As environmental issues are emerging, bio-plastic suppliers in leading countries have been foreseeing the strong needs for environment-friendly materials such as eco-packing materials due to increased attention and regulation on recycle. To catch up with the demand, various types of bio-plastics based on natural feedstocks were developed and released on a market. These bio-plastic products drew the great attention even in domestic industries. At present, international oil price fluctuation and heavy charge on waste raise the unit cost of production and disposal expense of conventional plastic materials. These conditions make bio-plastic an alternative, because it is not restrained by oil prices and problem in the disposal. It is also expected that bio-plastic will be applied to various types of products including containers, industrial supplies, disposables, and medical supplies. However, the bio-plastic is still in its infancy, thus more research and understanding should be followed to put it to application. Bio-plastic is considered as environment-friendly material with high potential which has the advantages of production and disposal.

• Archives of design research
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• v.13 no.4
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• pp.163-174
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• 2000

issued in the U.S is a magazine specialized in graphic design, which has a totally different style from commercial magazines such as show case. The main motive why Rudy VanderLans, the publisher, first issued this magazine in the early 1980s is his assertion that there is no design paradigm of universial concept in the aspect of viaual communication design. Also, it started from his recognition that a medium for letting a new generation's show their liberal thinking and experimental expressions. This study looks at theologies and assertions on new graphic concept, which is called the New Wave of graphic design by classifying the plans of into form and contents, and analyzes its specialty in design. Also, this study examines the overall trends of non-Grid editorial design since the modern style. By doing so, I could have a general look at the progressive traits and their futuristic directions that become to have a shorter life cycle with the advent of the 21st century's information era, high-tech media and the change of production environment by digital technology.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.29 no.2
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• pp.133-139
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• 2011

Estimation of biomass carbon stock is an important research for estimation of public benefit of forest. Previous studies about biomass carbon stock estimation have limitations, which come from the used deterministic models. The most serious problem of deterministic models is that deterministic models do not provide any explanation about the relevant effects of errors. In this study, the effects of location errors were analyzed in order to estimation of biomass carbon stock of Danyang area using Monte Carlo simulation method. More specifically, the k-Nearest Neighbor(kNN) algorithm was used for basic estimation. In this procedure, random and systematic errors were added on the location of Sample plot, and effects on estimation error were analyzed by checking the changes of RMSE. As a result of random error simulation, mean RMSE of estimation was increased from 24.8 tonC/ha to 26 tonC/ha when 0.5~1 pixel location errors were added. However, mean RMSE was converged after the location errors were added 0.8 pixel, because of characteristic of study site. In case of the systematic error simulation, any significant trends of RMSE were not detected in the test data.

• Cartoon and Animation Studies
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• s.17
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• pp.83-95
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• 2009

As an exploratory research on China's animation, this study aims to enhance an understanding of the trends and characteristics of China's animation through examining its history and to forecast its future development trajectory. From its founding to recent period, China tried to maintain Communist political system through imbuing national identity to its people through management and supervision of media products under direct government's leadership in combination with ideological education. Such policy was also implemented in animation, major audience of which is children. With regard to the introduction of the policy and its influence, five historical phases could be identified as follows. During the first phase, from the founding of the Republic until the Cultural Revolution, national culture was introduced to China's animation. The second phase, which corresponds with the Cultural Revolution period, marks the decline of national culture. National culture was reemphasized during the third phase that follows the Cultural Revolution, which led to the nomination of the 'China school,' followed by the fourth phase, during which China's animation suffered the second decline due to the spread of TVs and foreign animation imports. Reintroduction of national culture on China's animation in the context of rapid industrialization process before and after 2000 characterizes the recent phase. It can be expected that although there could be some change in methods and forms, China's animation, which introduced national culture from its inception and maintained remarkable resilience following the period of decline, will continuously stress the its own national cultural identity.

• The Journal of the Korea Contents Association
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• v.18 no.10
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• pp.320-334
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• 2018

The purpose of this study is to analyze research trends in international development and cooperation on education and to suggest directions for the Korean teachers and teacher education to achieve 'Sustainable Development Goals (SDGs).' The examination of 8 databases resulted in the identification of 2,945 studies, and 6 of these references met the inclusion criteria for systemic review. Major findings revealed that pre- and in-service teachers recognized the necessity of international development education but had a low degree of teacher efficacy. The teachers who participated in ODA education programs have experienced difficulties due to insufficient understanding of local sites and role performance. Then, a couple of studies of mathematics and early childhood education compared the Korean national curriculum and education system with developing countries'. Lastly, it is important to have a sustainable system which promotes all teachers, including retired ones, in global development and cooperation on education. For the successful achievement of SDGs, Korean teachers should develop their expertise, a deep understanding of partner countries, and stable quality education for the underprivileged.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.4
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• pp.664-673
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• 2018

The industrial control system (ICS) has operated as a closed network in the past, but it has recently been linked to information and communications services and has been causing damage due to cyber attacks. As a countermeasure, the Information Communication Infrastructure Protection Act was enacted, but it cannot be applied to various real control environments because there is only a one-way policy-from a control network to a business network. In addition, IEC62443 defines an industrial control system reference model as an international standard, and suggests an area security model using a firewall. However, there is a limit to linking an industrial control network, operating as a closed network, to an external network only through a firewall. In this paper, we analyze the security model and research trends of the industrial control system at home and abroad, and propose an industrial control system security model that can be applied to the actual interworking environments of various domestic industrial control networks. Also, we analyze the security of firewalls, industrial firewalls, network connection equipment, and one-way transmission systems. Through a domestic case and policy comparison, it is confirmed that security is improved. In the era of the fourth industrial revolution, the proposed security model can be applied to security management measures for various industrial control fields, such as smart factories, smart cars, and smart plants.

• Journal of Digital Convergence
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• v.16 no.2
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• pp.305-312
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• 2018

There is a general consensus that Baekjeing means Butcher after the Joseon Dynasty. In the Goryeo Dynasty, the title of "Baekjeong" was named as a general farmer's name, "Hwacheok" and "Jaecheok" from the north, but it changed its name to Shin Baekjeong by nationalization policy in the early Joseon Dynasty. They were multicultural Ancestors who worked for jobs which people despised. The purpose of this study is to examine the background and trends of how these were stripped of their identity and to present a direction for deciding on the policy of multiculturalism which is the subject of our society today. Based on the researches of historical researchers, the study examines the multicultural dynamics of old period and observes the present phenomenon by interpreting the statistics of the related institutions of the government. We realized that the reason for the liberation of the Baekjeong has a various causes and its causes are similar to the phenomenon of today 's multicultural society, so that the depth research on each factor will be added to form a desirable policy base for multiculturalism in our country.

• Journal of the Korean Crystal Growth and Crystal Technology
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• v.22 no.5
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• pp.233-240
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• 2012

White LEDs (light-emitting diodes) are promising new-generation light sources which can replace conventional lamps due to their high reliability, low energy consumption and eco-friendly effects. This paper briefly reviews recent progress of oxy/nitride host phosphor and quantum dot materials with broad excitation band characteristics for phosphor-converted white LEDs. Among oxy/nitride host materials, $M_2Si_5N_8$ : $Eu^{2+}$, $MAlSiN_3$ : $Eu^{2+}$ M-SiON (M = Ca, Sr, Ba), ${\alpha}/{\beta}$-SiAlON : $Eu^{2+}$ are excellent phosphors for white LED using blue-emitting chip. They have very broad excitation bands in the range of 440~460 nm and exhibit emission from green to red. In this paper, In this review we focus on recent developments in the crystal structure, luminescence and applications of the oxy/nitride phosphors for white LEDs. In addition, the application prospects and current trends of research and development of quantum dot phosphors are also discussed.