• 대한상한금궤의학회지
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• 제12권1호
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• pp.183-198
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• 2020

Objective: The purpose of this study was to report improvement in patients with autism spectrum disorder (ASD) treated with herbal medication described in Shanghanlun. Methods: The patient was diagnosed with Lesser Yin disease based on the 315^th provision of Shanghanlun, and Baektonggajeodamjup-tang was used for treatment. The result was evaluated using the Korean-Childhood Autism Rating Scale (K-CARS). Results: The K-CARS score decreased from 32 to 15 after 7 months of treatment. Conclusions: Lesser Yin disease 315^th provision of Shanghanlun may be a provision describing ASD; in addition, Baektonggajeodamjup-tang may be an effective treatment for ASD.

• 대한한방소아과학회지
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• 제29권1호
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• pp.50-59
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• 2015

Objectives The purpose of this study is to report seven cases of autism spectrum disorder treated by oriental medicine. Methods Seven patients who are diagnosed with autism spectrum disorder were treated with herbal medicine (Kwakhyangjungkisanhapyukmijihwangtang-gamibang), and the effect was measured. Results After the treatment, cognitive skill, speech, motor function, communication skill, and the patients' general conditions have gotten better. Conclusions This study has shown that the oriental medical treatment for autism spectrum disorder was effective, but further studies are needed.

• 융복합기술연구소 논문집
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• 제1권2호
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• pp.1-5
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• 2011

It is known that as many as 15-20 in 10,000 children are diagnosed with autistic spectrum disorder. A framework of the treatment system for children with autism using affective computing technologies was proposed by Chung and Yoon. In this paper, a prototype for the framework is proposed. It consists of emotion stimulating module, multi-modal bio-signal sensing module, treatment module using virtual reality, and emotion recognition module. Primitive experiments on emotion recognition show the usefulness of the proposed system.

• Clinical and Experimental Pediatrics
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• 제62권11호
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• pp.405-409
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• 2019

A structured review study of drug interventions on sleep disorders in patients with autism spectrum disorders (ASD) has not been published to date. This systematic review aimed to investigate drug interventions for the treatment of sleep disorders in children with ASD. The Web of Science, PubMed, and Scopus databases were searched until March 2019. Study quality was assessed using the Delphi checklist. Due to the heterogeneity of the findings, a meta-analysis was not possible. Drug interventions for the treatment of sleep disorders in patients with ASD included melatonin, atomoxetine, and risperidone. Atomoxetine had no effect on sleep disorders in patients with ASD. A total of 10 studies were reviewed. Melatonin appears to be useful for the treatment of sleep problems in patients with ASD, but further studies are needed to determine the effects of other drugs.

• 대한한방소아과학회지
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• 제29권4호
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• pp.119-126
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• 2015

Objectives The purpose of this study is to investigate recent clinical studies on effect of acupuncture for Autism Spectrum Disorder in other countries. We have analyzed the studies on effect of acupuncture for Autism Spectrum Disorder within randomized controlled trail (RCT) for 6years (from 2010 to 2015). Methods The search database includes Medline, Embase, Cochrane library and CNKI (China National Knowledge Infrastructure). To narrow the search, the following key search terms were used: 'autism or ASD or Asperger's Syndrome or pervasive developmental disorder, acupuncture'. The search was limited to the publication date from 2010 to 2015. 7 control studies in Medlin, Embase, Cochrane library and 5 control studies in CNKI were selected for analysis. Results and Conclusions 1. The acupuncture and rehabiliation treatment is more effective than only acupuncture treatment. Especially, Retention of needling is helpful. 2. It is necessary to set up standard scale in assessment of ASD patients and serum arginine-vasopressin (AVP) can be substitution. 3. Head acupuncture and tongue acupuncture is effective for ASD.

• 대한감각통합치료학회지
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• 제17권1호
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• pp.30-42
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• 2019

목적 : 본 연구는 자해행동을 보이는 자폐스펙트럼장애의 비약물적 치료 중심으로 실시한 연구를 대상으로 체계적으로 분석하여 작업치료 임상현장에서 동일한 문제를 보이는 자폐스펙트럼장애 아동에게 적절한 서비스를 제공하기 위한 근거를 마련하고자 한다. 연구방법 : 전자데이터 베이스인 PubMed, Medline, DBpia, RISS, KISS, NDSL을 사용하여 2008년 10월부터 2018년 11월까지 국내외 학회지에 게재된 연구를 대상으로 검색하였다. 주요 용어는"(Autism OR Autism Spectrum Disorder) AND (Therapy OR Treatment OR Intervention) AND (Self Injurious Behavior)"으로 검색하였고, PICO형식과 근거수준을 사용해 분석하였다. 연구결과 : 총 12편의 논문이 선정되었고, 근거의 질적 수준은 대상연구 논문 12편 중 수준 IV와 수준 V가 가장 많았으며, 실험설계는 단일대상연구가 많았다. 중재의 종류는 행동치료가 가장 많았다. 분석결과 자폐스펙트럼장애의 자해행동은 행동치료와 뇌자극 및 조절기법, 행동치료와 병행한 감각통합치료로 자해행동을 감소시켰으며 통계적으로도 유의한 결과를 보였다. 결론 : 자해행동을 보이는 자폐스펙트럼 장애 아동에게 적용한 비약물적 중재에 대한 근거자료를 제시하였다. 앞으로 자폐스펙트럼 장애 아동의 자해행동에 대한 중재효과성을 증명하기 위하여 근거수준이 높은 연구 설계와 다양한 비약물적 중재간의 차이점을 밝히는 연구가 지속적으로 이루어져야 할 것이다.

• 대한한방소아과학회지
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• 제19권2호
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• pp.85-97
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• 2005

Objective : The purpose of this study is to assess the clinical effect of Yukmijihawangtang gamibang on autism. Methods : This clinical study was carried out with two atypical autistic children. We treated them with the herb medicine(Yukmijihawangtang gamibang) for several months and observed them once a month. And we checked the dregrees of autism with Korean-Autism Diagnostic Scale at June 29 and October 13. Results : Two cases's dregrees of autism were improved significantly. Autistic probability of case 1 was below the average at first test and very low at second test And case 2 was above the average at first test and very low at second test. And language was improved at last. Conclusion : Yukmijihawangtang gamibang was effective in the treatment of autism and more study about this disease is needed.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• 제20권1호
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• pp.39-43
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• 2009

We treated the persistent ruminative vomiting of a 13-year-old autistic boy by using a behavioral and psychopharmacological approach in a closed ward. Before the interventions, the patient had lost about 10kg of body weight due to very high-frequency ruminative vomiting. Together with psychopharmacological trials, the psychiatric treatment included a combination of a behavioral approach and food regulation that emphasized food restrictions, and we provided regular light meals. There was a considerable reduction of the ruminative vomiting and 2kg weight gain was achieved during the admission. These therapeutic gains were maintained at the 4-month follow-up assessment and the vomiting symptom reached a near-zero level and the weight loss were recovered by about 8kg. The issues related to the treatment approaches for ruminative vomiting with autism are discussed.

• 대한소아치과학회지
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• 제38권2호
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• pp.181-186
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• 2011

자폐는 사회적 상호작용의 장애, 의사소통의 장애, 행동, 관심 및 활동이 한정되고 반복적이며 상동적인 양상을 나타내는 것으로 정의 될 수 있다. 자폐아의 경우 치과 치료시 협조를 얻어내는 것이 용이하지 않으며 자폐의 심도나 환아의 협조도 구강 상태 및 전신상태 등을 고려하여 행동 수정법, 약물을 이용한 진정요법, 전신마취 등을 통해 보다 효율적인 치과치료를 시행할 수 있다. 치과치료에 협조가 가능한 경증의 행동장애 또는 중등도의 행동장애를 보이는 경우 일반적인 행동 수정법과 진정요법으로 치료가 가능할수 있다. 그러나 환아의 협조도가 매우 불량하고 많은 양의 치과치료가 필요한 경우 한 번의 전신마취를 통해 환자는 여러번의 내원으로 인한 비용, 시간, 불안감을 줄일 수 있다. 본 증례는 충치치료를 주소로 연세대학교 원주기독병원 소아치과에 내원한 자폐로 진단받은 환아에서 각각의 자폐 심도에 따른 행동 조절법을 적용한 치과치료를 시행하고 다소의 지견을 얻었기에 보고하고자 한다.

• Journal of Dental Anesthesia and Pain Medicine
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• 제17권2호
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• pp.157-161
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• 2017

In sedation via the submucosal route, the drug is administered through the maxillary buccal submucosa. It is time saving, effective, and safe. Patients with autism, a mental disorder, often find it hard to make relationships with other people. These patients display a strong resistance to dental treatment and sedation. This study reports a successful case of behavioral management during dental treatment, using sedation via the submucosal route. The patient was strongly resistant to sedation via the oral, intramuscular, and intravenous routes. The drug used was 9 mg (0.1 mg/kg) of midazolam. Through this case report, we reaffirm the significance of sedation via the submucosal route, and expect that it will be used more frequently for patients with autism, who display behaviors that are difficult to manage, patients with other disabilities, and children.