• Title/Summary/Keyword: Treatment efficacy

Search Result 4,333, Processing Time 0.029 seconds

The Effect of Microteaching on Self Efficacy and Speech Anxiety for Student Health Educators (마이크로티칭이 예비보건교육사의 자기효능감 및 발표불안에 미치는 효과)

  • Kwon, Myung-Soon;Cho, Hae-Ryun
    • Journal of Korean Public Health Nursing
    • /
    • v.26 no.1
    • /
    • pp.91-100
    • /
    • 2012
  • Purpose: The purpose of this study was to examine the effects of microteaching for student health educators. Methods: Subjects included 43 students in the nursing department of "H" university. In order to measure the degree of self-efficacy and speech anxiety at pre-treatment and post-treatment, subjects in the experimental group underwent training in microteaching. Results: No significant difference of variance in self-efficacy and speech anxiety was observed between subjects in the experimental group and those in the control group. However, self-confidence, a sub-domain of self-efficacy, showed a significant increase from pretest to post-test. In addition, speech anxiety measured during the post-test showed improvement, when compared with that of the pretest. Conclusion: Findings of this study provide preliminary evidence that microteaching may result in improved speech behavior.

Comprehensive Analysis of Temozolomide Treatment for Patients with Glioma

  • Yang, Wen-Bing;Xing, Bian-Zhi;Liang, Hua
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.19
    • /
    • pp.8405-8408
    • /
    • 2014
  • Background: This analysis was conducted to evaluate the efficacy and safety of temozolomide based chemotherapy in treating patients with glioma. Methods: Clinical studies evaluating the efficacy and safety of temozolomide based regimens for patients with glioma were identified using a predefined search strategy. Pooled response rates (RRs) were calculated. Results: In temozolomide based regimens, 5 clinical studies including 152 patients with advanced glioma were considered eligible for inclusion. Four clinical studies included temozolomide. Systematic analysis suggested that, in all patients, pooled CR was 21% (32/152), and PR was 21% (32/152). Grade 3/4 toxicity included neutropenia, thrombocytopenia, and anemia. No grade 3 or 4 renal or liver toxicity was observed. No treatment related death occurred with temozolomide based treatment. Conclusion: This systematic analysis suggests that temozolomide based regimens are associated with mild response rate and acceptable toxicity for treatment of glioma patients.

Evaluation of Different Bed Disinfectants against the Spread of Common Diseases in Silkworm, Bombyx mori L.

  • Irfan Illahi;S. D. Sharma;K. Chrasekharan;B. Nataraju;M. Balavenkatasubbaiah;T. Selvakumar;V. Thiagarajan;S. B. Dandin
    • International Journal of Industrial Entomology and Biomaterials
    • /
    • v.6 no.2
    • /
    • pp.191-196
    • /
    • 2003
  • Silkworm body and rearing seat disinfection is an integral part of effective silkworm rearing as it prevents the spread of various diseases through secondary contamination in the rearing bed. Many bed disinfectants are recommended by various research institutes in India. In the present study, eight bed disinfectants viz., Vijetha, Labex, Resham Jyothi, Sanjeevini, Suraksha, Reshamkeet Oushadh, Dithane M45 and Captan recommended by various Sericultural Research Institutions in the country against the spread of common diseases of silkworm were tested to determine their comparative efficacy. For the study, all the treatment batches were introduced with fixed number of specific diseased larvae so as to maintain a constant source of pathogen in the bed and then followed by treatment with respective bed disinfectants. Percent mortality/infection due to each disease was recorded to determine efficacy of bed disinfectant treatment against respective disease. The results show that all the bed disinfectants tested have considerable efficacy against the spread of various diseases in the rearing bed. However, Vijetha was distinctly superior in its efficacy against all four major diseases of silkworm. The study emphasize the role of bed disinfectants in silkworm rearing and the fact that they should be judiciously selected based on the efficacy of the bed disinfectant and the type of disease prevalent in a particular season and area.

Effects of Abstinence Self-efficacy and Social Support on Relapse Risk in Community-dwelling Adults with Alcohol Use Disorder (지역사회에 있는 알코올 사용 장애자의 금주 자기효능감, 사회적 지지가 재발 위험성에 미치는 영향)

  • Kim, Mi Hye;Hyun, Myung Sun
    • Journal of Korean Academic Society of Home Health Care Nursing
    • /
    • v.29 no.2
    • /
    • pp.194-203
    • /
    • 2022
  • Purpose: This study investigated the factors influencing the risk of relapse in community-dwelling adults with alcohol use disorder. Methods: This study included 122 community-dwelling individuals with alcohol use disorder who were receiving outpatient treatment at a mental health treatment hospital or were enrolled in a treatment program at the Community Addition Management Center in Gyeonggi Province. Data were collected using self-administered questionnaires from July to August 2020. Data were analyzed using descriptive statistics, independent t-test, one-way ANOVA, Pearson's correlation coefficient, and multiple regression analysis using SPSS 25.0. Results: Abstinence self-efficacy (𝛽=-.56, p<.001), social support (𝛽=-.35, p=.009), female sex (𝛽=11.29, p=.015), and a family history of alcoholism (𝛽=9.41, p=.026) were significant predictors of relapse risk, accounting for 56% of the variance (F=12.68, p<.001). Conclusion: The findings of this study suggest that abstinence self-efficacy and social support are pivotal in reducing risk of relapse in individuals with alcohol use disorder. Therefore, relevant and effective interventions focusing on enhancing abstinence self-efficacy and social support are required.

The Effects of Medical Students' Self-Directed Learning Ability, Self-regulated Learning, and Communication Ability on Self-Efficacy in Performing Medical Treatment (의과대학생의 자기주도학습능력, 자기조절학습, 의사소통능력이 진료수행 자기효능감에 미치는 영향)

  • Nam Joo Je;Ji-Won Yoon;Jeong Seok Hwa
    • The Journal of the Convergence on Culture Technology
    • /
    • v.10 no.3
    • /
    • pp.267-278
    • /
    • 2024
  • This study was a descriptive research study targeting medical students to determine the impact of self-directed learning ability, self-regulated learning, and communication ability on self-efficacy in performing medical treatment. This study randomly selected medical students from Region J, located in Province G, as the approximate population, and a total of 125 copies were finally analyzed. Descriptive statistics were analyzed using t-test, ANOVA, correlation, and multiple regression analysis using IBM SPSS/25. Self-efficacy in performing medical treatment was related to self-directed learning ability (r=.61, p<.001), self-regulated learning (r=.50, p<.001), and communication ability (r=.33, p<.001). There was a positive correlation with all of them. As a result of analyzing the variables that affect the subject's self-efficacy in performing medical treatment using hierarchical multiple regression, self-directed learning ability was found to be the factor that best predicts self-efficacy in performing medical treatment, followed by self-regulated learning and communication ability. The total explanatory power was 46.6%. Acquiring specialized knowledge and becoming a doctor after graduation through clinical practice and acquiring the basic clinical practice skills necessary to successfully perform one's duties are important tasks that medical students must accomplish. Therefore, in order to improve medical students' self-efficacy in performing medical treatment, the importance of improving health care, major satisfaction, and life satisfaction must be recognized and managed. In addition, efforts to develop programs and improve systematic systems that can improve self-directed learning, self-regulated learning, and communication skills should also be supported.

Pharmacopuncture for Cervicogenic Dizziness

  • Kim, Yunna;Cho, Seung-Hun
    • Journal of Pharmacopuncture
    • /
    • v.21 no.4
    • /
    • pp.241-248
    • /
    • 2018
  • Objectives: Pharmacopuncture is a treatment that medicinal fluid including herbal extract is injected in body under qi/flavor theory and meridian theories. There are a number of studies investigating the efficacy of pharmacopuncture for cervicogenic dizziness but its usage differs in each study. This study aimed to review previous studies of pharmacopuncture treatment for cervicogenic dizziness to navigate the direction of improvement. Methods: Literature review was conducted on studies aimed at pharmacopuncture for cervicogenic dizziness. The randomized controlled studies which assessed the efficacy of pharmacopuncture on cervicogenic dizziness were selected. The studies were searched in Pubmed, RISS, OASIS and CNKI. After selecting eligible studies, the authors read the articles and summarized the points those are necessary in pharmacopuncture treatment for cervicogenic dizziness. Results: Twenty seven studies and 2,709 participants were included. The diverse solutions were used and the most popular were Salvia miltiorrhiza, Angelica gigas, a compound in Gastrodia elata, Panax notoginseng saponins. Some studies investigated the efficacy of conventional medical compounds (lidocaine, vitamin B, dexamethasone) injected in acupoints. Adopting acupoints and combining with body acupuncture have shown the tendency to enhance the cure rate. Pharmacopuncture could improve the efficacy of conventional treatment for cervicogenic dizziness. Conclusion: As the solution and injection method varies, principles of pharmacopuncture for dizziness should be investigated.

Clinical Observation and Prognostic Analysis of Pemetrexed plus Platinum as First-line Treatment in Patients with Advanced Non-small Cell Lung Cancer

  • Wang, Ji-Ying;Cai, Yong
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.14 no.11
    • /
    • pp.6267-6271
    • /
    • 2013
  • Objective: To determine clinical efficacy, safety and prognostic factors of pemetrexed plus platinum as first-line treatment in patients with advanced non-small cell lung cancer (NSCLC). Materials and Methods: Clinical characteristics, short-term efficacy, survival and adverse reactions of 47 advanced non-squamous NSCLC patients who had received pemetrexed plus platinum as first-line treatment in Shanghai Pulmonary Hospital from January 2009 to June 2011 were retrospectively analyzed. The Chi-squared test was applied to statistically analyze the overall response rate (ORR), disease control rate (DCR) and toxicity reactions in both groups, while survival data wereanalyzed by Kaplan-Meier and logrank methods, and the COX proportional hazards model was adopted for a series of multi-factor analyses. Results: Only two patients were lost to follow-up. The ORR, DCR, medium progression-free survival time (PFS) and medium overall survival (OS) were 31.9%, 74.5%, 5 months and 15.2 months, while 1- and 2-year survival rates were 63.8% (30/47) and 19.2% (9/47), respectively. Single-factor analysis showed that tumor pathological patterns and efficacy were in association with medium PFS (P<0.05), whereas tumor pathological patterns, smoking history and efficacy were closely connected with medium OS (P<0.05). Multi-factor analyses demonstrated that pathological patterns and efficacy were independent factors influencing OS (P<0.05). The rate of toxicity reactions in degree III/IV was low, including hematologic toxicity marked by decline in white blood cell count and decrease in the platelet count (PLT), and non-hematologic toxicity manifested by gastrointestinal reactions, such as nausea and vomiting. Conclusions: Pemetrexed plus platinum as first-line treatment has excellent efficacy and slight adverse reactions with favorable drug-tolerance in patients with advanced non-squamous NSCLC.

Effects of Electrical Stimulation Therapy on Chronic Knee Pain, Exercise Self-Efficacy, and Quality of Life in Korean Elderly Women (전기 자극이 여성 노인의 만성 무릎통증, 운동자기효능 및 삶의 질에 미치는 효과)

  • Sok, So Hyune
    • Korean Journal of Adult Nursing
    • /
    • v.19 no.3
    • /
    • pp.508-516
    • /
    • 2007
  • Purpose: This study was to examine the effects of electric stimulation therapy on chronic knee pain, exercise self-efficacy, and quality of life in Korean elderly women. Methods: The design was an unequivalent control pretest-posttest study. Samples were total of 60 (experimental: 30, control: 30) elderly women with healthy cognitive and communication abilities aged 65 years old and above. The experimental treatment involved was the electric stimulation of both thigh quadriceps muscles for 15 minutes per treatment, 3times per a week, for a total of 12 weeks. Measurements taken were S-F MPQ and AIMS for chronic knee pain, exercise self-efficacy measurement for exercise self-efficacy, and S-F 36 scale for quality of life. Data were analyzed using SPSS PC+ 12. Results: Chronic knee pain according to the Short-Form McGill Pain Questionnaire (t=43.563, p=.000) and Arthritis Impact Measurement Scale (t=31.364, p=.000) were significantly decreased in the experimental group by the application of electrical stimulation therapy. Exercise self-efficacy (t=107.116, p=.000) and quality of life (t=76.429, p=.000) were significantly increased in the experimental group by the application of electrical stimulation therapy. Conclusion: Electrical stimulation therapy could be a more effective primary nursing intervention in decreasing chronic knee pain, and on increasing exercise self-efficacy and quality of life for Korean elderly women.

  • PDF

Effects of Club Obesity Management Program for Obese Children on Body Composition, Self Efficacy, and Health Promotion (동아리활동 비만관리 프로그램이 비만아동의 신체조성, 자기효능, 건강증진행위에 미치는 효과)

  • Nam, Soung Mi
    • Journal of Korean Public Health Nursing
    • /
    • v.27 no.3
    • /
    • pp.619-632
    • /
    • 2013
  • Purpose: The purpose of this study was to develop an obesity management program for obese children and examine its effects on body composition, self-efficacy, and health promotion. The obesity management program was based on a KAP & HBM mixed model and consisted of health education and group playing exercises. Method: This study was implemented at one elementary school in K city for a total of 12 weeks. The study subjects were a single group, and their body composition, self-efficacy, and health promotion were assessed at both pre-treatment and post-treatment. Data were analyzed by Wilcoxon Signed Rank Test using SPSS WIN 20.0. Result: After the program, the average height of subjects increased by 0.9cm (p=.001), whereas BMI decreased by $0.64kg/m^2$ (p=.003), obesity index decreased by 3.79% (p=.003), and body fat decreased by 1.34% (p=.002). There were significant effects on diet self-efficacy (p=.027), exercise self-efficacy (p<.001), and health promotion (p=.001). Conclusion: This obesity management program reduced the degree of obesity and improved self-efficacy and health promotion. Therefore, the obesity management program is an effective intervention method for elementary-aged obese children.

Efficacy of proton pump inhibitors and H2 blocker in the treatment of symptomatic gastroesophageal reflux disease in infants

  • Azizollahi, Hamid Reza;Rafeey, Mandana
    • Clinical and Experimental Pediatrics
    • /
    • v.59 no.5
    • /
    • pp.226-230
    • /
    • 2016
  • Purpose: Gastroesophageal reflux disease (GERD) occurs in pediatric patients when reflux of gastric contents presents with troublesome symptoms. The present study compared the effects of omeprazole and ranitidine for the treatment of symptomatic GERD in infants of 2-12 months. Methods: This study was a clinical randomized double-blind trial and parallel-group comparison of omeprazole and ranitidine performed at Children Training Hospital in Tabriz, Iran. Patients received a standard treatment for 2 weeks. After 2 weeks, the patients with persistent symptoms were enrolled in this randomized study. Results: We enrolled 76 patients in the present study and excluded 16 patients. Thirty patients each were included in group A (ranitidine) and in group B (omeprazole). GERD symptom score for groups A and B was $47.17{\pm}5.62$ and $51.93{\pm}5.42$, respectively, with a P value of 0.54, before the treatment and $2.47{\pm}0.58$ and $2.43{\pm}1.15$, respectively, after the treatment (P=0.98). No statistically significant differences were found between ranitidine and omeprazole in their efficacy for the treatment of GERD. Conclusion: The safety and efficacy of ranitidine and omeprazole have been demonstrated in infants. Both groups of infants showed a statistically significant decrease in the score of clinical variables after the treatment.