• 대한한방부인과학회지
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• 제29권2호
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• pp.113-120
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• 2016

Objectives: This study aims to report the effects of Korean medicine treatment by pattern identification and Sweet Bee Venom Pharmacopuncture on Chronic Relapsing Cystitis Methods: The patients was treated with Korean medicine by pattern identification and Sweet Bee Venom Pharmacopuncture at Qugu (CV2), Guanyuan (CV4). We evaluated treatment effects by changes of symptoms and urine analysis (UA) finding. Results: After treatments, the clinical symptoms such as painful urination, dysuria, frequent urination were improved and the state of urinalysis was improved. Conclusions: This clinical study suggests that Korean medicine treatment by pattern identification and Sweet Bee Venom Pharmacopuncture are significantly effective in treatment of a Chronic Relapsing Cystitis

• 한국임상수의학회지
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• 제7권1호
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• pp.407-414
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• 1990

This study was performed to evaluate the effects of doxapram after succinylcholine treatment. Succinylcholine was administered intravenously at a dose rate of 0.07 mg per kg of body weight and then ten minutes after the injection of succinylcholine doxapram was administered intravenously at a dose rate of 2 mg per kg of body weight. The results obtained were as follows : 1. Recovery time in dog given doxapram after succinylcholine treatment was shortened comparing with control group. 2. The changes in respiratory rate revealed a maximal increase immediately after the injection of doxapram. Thereafter respiratory rate gradually decreased, and revealed normal levels 20 minutes after the injection of doxapram. 3. The changes in heart rate revealed a maximal increase immediately after the injection of doxapram. Thereafter heart rate gradually decreased, but remained above the levels of control group. 4. Although arrhysthmias were observed after treatment of succinylcholine, these were disappeared after doxapram treatment. And there was no another change on electrocardiograms.

• Biomolecules & Therapeutics
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• 제9권4호
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• pp.244-248
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• 2001

This study was performed to investigate therapeutic effects of Carthami Semen, Paeoniae Raidx extracts and chitosan on the growth and differentiation of human periodontal ligament cell. We found that co-treatment of methanol extracts of Carthami Semen and chitosan significantly increased the growth of human periodontal ligament cell. However, the sigle treatment groups of the extracts showed only 20-30% of the growth increase. Alkaline phosphase activity, one of differentiation markers, was increased approximately 1.5- fold by co-treatment of methanol extract of Carthami Semen and chitosan and calcified nodule formation was also increased at the similar levels as the alkaline phosphatase. But the single treatment groups showed only 20-30% increases. These results suggest that Carthami Semen and chitosan co-treatment can be used efficiently for periodontium regeneration.

• 한국식품위생안전성학회지
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• 제10권4호
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• pp.249-254
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• 1995

In order to study the effects of Aloe vera Linne treatment on the clinical chemistry in patients with liver disease, seven patients were administered orally with 800~1, 600 mg of Aloe vera Linne four times day for six months. The high levels of serum AST, ALT, ALP, ${\gamma}$-GTP and total bilirubin in patients were significantly reduced by adminstration of Aloe vera L. The reduced serum albumin/globulin value was increased by Aloe vera L. treatment. But other blood parameters of clinical chemistry values were not affected by Aloe vera L. treatment. These data suggest that Aloe vera L. can be effective in treatment of the patients with liver disease.

• Korean Journal of Acupuncture
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• 제21권3호
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• pp.121-136
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• 2004

Objectives : The purpose of this study is to identify the clinical effects of auricular acupuncture in the treatment of dysmenorrhea. Methods : Auricular acupuncture treatments were prescribed to 29 dysmenorrhea patients 1 time a week for 13 weeks. Results : After the treatment, numerical index for the pain was obviously reduced 'tot' point 2.61. It means that pain index as the patient has difficulty in daily life was reduced to 2 grades enough to do ordinary experience. Conclusions : This study shows that auricular acupuncture treatment has remarkable effects on dysmenorrhea.

• 상하수도학회지
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• 제14권2호
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• pp.164-173
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• 2000

Fluoridation of drinking water to a level of about 0.8mg/l (below 1.5mg/l) for reducing the incidence of tooth decay is recommended. However, concerns about potential problems of unknown effects and overdosing hinders the fluoridation. This study describes the work performed to obtain information on the behavior of fluoride under various conditions in the process of water fluoridation. Effects of water treatment chemicals, water treatment unit, and water distribution on water fluoridation were investigated at both lab and an actual water treatment plant. Residual fluoride concentration was not affected by lime and chlorine dosage up to 20mg/l. Flocculation with PAC slightly decreased the residual fluoride concentration as PAC dosage increased. Average fluoride concentration of 0.87mg/l at an intake basin was decreased to 0.83mg/l by sedimentation, 0.81mg/l by dual media(sand+anthracite) filtration, and 0.79mg/l by granular activated carbon filtration in the water treatment plant.

• 한국표면공학회지
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• 제26권2호
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• pp.71-81
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• 1993

Thed effects of Ar or Oxygen RF plasma treatment on the adhesion behavior of Cr films to polyimide sub-strates have been investigated by using SEM, XRD, AES, and $90^{\circ}$peel test. By applying RF plasma treatment of the polyimide surface prior to metal deposition, the peel adhesion strength of Cu/Cr films sputtered onto the fully cured BPDA-PDA polyimide was highly increased from about 3g/mm to 90 ~ 100g/mm. Improved peel adhesion strength of Cr/polyimide interfaces due to RF plasma treatment was attributed to the contributions from surface cleaning, Cr-polyimide bonding at the interface, and force required for plastic deformation of the film. While the surface topology change of the polyimide caused by RF plasma treatment makes a little contri-bution to the improved adhesion.

• Macromolecular Research
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• 제11권5호
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• pp.387-392
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• 2003

The ablation effects of Ar-plasma treatment and alkali-decomposition behavior in NaOH solution of polyethylene terephthalate (PET) film were investigated. The modifications were evaluated by analysis of atomic force microscopy topographical changes, and by the measurement of decomposition yield in conjunction with heats of formation and electron densities of acyl carbon calculated by Parameterization Method 3 method. It has shown that the alkali-decomposition is hampered by plasma treatment and its decomposition yield is closely related with plasma treatment conditions such as exposure time to plasma. Plasma-treated PET films exhibited lower decomposition yield, compared to that of virgin PET. Increasing plasma exposure time contributes positively to decrease the decomposition yield. It has also shown that the topography of PET surface was affected by the base-promoted hydrolysis as well as Ar-plasma treatments. These behaviors are attributed to the decreased nucleophilicity of acyl carbon damaged by the ablation of Ar-plasma.

• 약학회지
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• 제57권1호
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• pp.18-23
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• 2013

The objective of this study is to evaluate the synergic effects of combined treatment with taurine and cisplatin in human breast cancer, MCF-7 cells. For this study, MCF-7 cells were treated with taurine (5, 10, and 20 mM) and cisplatin (0.5 ${\mu}M$) for 48 and 72 hrs. Co-treatment of cisplatin with taurine decreased cell proliferation more compared with cisplatin alone. Reduced cell proliferation was caused by apoptosis. Therefore we investigated the apoptotic cells. After treatment of cisplatin and taurine, apoptotic cells were slightly increased. Apoptosis-related proteins, cleaved caspases and cytochrome c were increased. The present study suggests that combination treatment of cisplatin with taurine enhance anticancer activity of cisplatin in MCF-7 cells.

• 대한약침학회지
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• 제5권1호
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• pp.7-26
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• 2002

Objective: The purpose of this study was to investigate acute and subacute toxicity and sarcoma-180 anti-cancer effects of herbal acupuncture with Carthami- Tinctorii fructus (CF) in mice and rats. Method: Balb/c mice were injected intraperitoneally with Carthami - Tinctorii fructus (CF) for $LD_{50}$ and acute toxicity test. Sprague Dawley rats were injected intraperitoneally with Carthami- Tinctorii fructus (CF) for subacute toxicity test. The Carthami- Tinctorii fructus herbal-acupuncture was injected on Chung-wan (CV12) of mice with Sarcoma-180 cancer cell line. Results: 1. $LD_{50}$ was uncountable as none of the subjects expired during the test. 2. In acute toxicity test, toxic symptoms were not detected, but the body weight of mice was increased in treatment Ⅰ, treatment Ⅱ groups, compared to the normal group.(p<0.05) 3. In acute toxicity test of serum biochemical values of mice, glucose was increased in treatment Ⅰ and treatment Ⅱ groups, total cholesterol was increased in treatment I group, GOT was decreased in treatment Ⅱ group, and GPT was decreased in treatment Ⅰ group, compared to the normal group.(p<0.05) 4. The clinical signs and the body weight of mice treated with 0.1 cc, 0.2cc Carthami- Tinctorii fructus (CF) were not affected during the subacute toxicity test. 5. In subacute toxicity test, treatment groups didn't show significant changes in complete blood count test (CBC) of rats, compared to the nonnal group.(p<0.05) 6. In subacute toxicity test of serum biochemical values of rats, uric acid was decreased in treatment Ⅰ and treatment Ⅱ groups, compared to the nonnal group, triglyceride was decreased in treatment I group, compared to the normal group, GOT and GPT were decreased in treatment I and treatment Ⅱ groups, and alkaline phosphatase was decreased in treatment Ⅰ and treatment Ⅱ groups, compared to the normal group.(p<0.05) 7. Median survival time was increased in all the treatment groups for Sarcoma-180 cancer cell treated with Carthmni- Tinctorii fructus (CF).(p<0.05) 8. Natural killer cell activity was significantly increased in all the treatment groups compared to the normal group.(p<0.05) 9. Interleukin-2 productivity was decreased in treatment Ⅰ and treatment Ⅱ groups.(p<0.05) Conclusion: According to the results, we can conclude herbal-acupuncture of Carthami-Tinctoriifructus (CF) caused negligible toxkity, and had anti-tumor effects in mice.